DE3861484D1 - Indanamin-derivate als antiarrhythmische mittel. - Google Patents

Indanamin-derivate als antiarrhythmische mittel.

Info

Publication number
DE3861484D1
DE3861484D1 DE8888302600T DE3861484T DE3861484D1 DE 3861484 D1 DE3861484 D1 DE 3861484D1 DE 8888302600 T DE8888302600 T DE 8888302600T DE 3861484 T DE3861484 T DE 3861484T DE 3861484 D1 DE3861484 D1 DE 3861484D1
Authority
DE
Germany
Prior art keywords
arrhythmic agent
alkyl
compounds
indanamine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8888302600T
Other languages
English (en)
Inventor
Peter Edward Dr Cross
John Edmund Dr Arrowsmith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Application granted granted Critical
Publication of DE3861484D1 publication Critical patent/DE3861484D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/02—Monoamides of sulfuric acids or esters thereof, e.g. sulfamic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
DE8888302600T 1987-03-25 1988-03-24 Indanamin-derivate als antiarrhythmische mittel. Expired - Lifetime DE3861484D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878707123A GB8707123D0 (en) 1987-03-25 1987-03-25 Antiarrhythmic agents

Publications (1)

Publication Number Publication Date
DE3861484D1 true DE3861484D1 (de) 1991-02-14

Family

ID=10614609

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888302600T Expired - Lifetime DE3861484D1 (de) 1987-03-25 1988-03-24 Indanamin-derivate als antiarrhythmische mittel.

Country Status (12)

Country Link
US (1) US5006561A (de)
EP (1) EP0286278B1 (de)
JP (1) JPS63264556A (de)
AT (1) ATE59842T1 (de)
AU (1) AU593739B2 (de)
DE (1) DE3861484D1 (de)
DK (1) DK160788A (de)
ES (1) ES2036674T3 (de)
GB (1) GB8707123D0 (de)
GR (1) GR3001665T3 (de)
IE (1) IE61071B1 (de)
PT (1) PT87051B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8809314D0 (en) * 1988-04-20 1988-05-25 Wellcome Found Anti-hypertensive sulfonanilides
JP2931986B2 (ja) * 1989-02-17 1999-08-09 武田薬品工業株式会社 アラルキルアミン誘導体
US5166209A (en) * 1989-04-21 1992-11-24 Burroughs Wellcome Co. Pharmacologically active compounds
WO1991009594A1 (en) * 1989-12-28 1991-07-11 Virginia Commonwealth University Sigma receptor ligands and the use thereof
WO1995000131A1 (en) * 1993-06-23 1995-01-05 Cambridge Neuroscience, Incorporated Sigma receptor ligands and the use thereof
US5382587A (en) * 1993-06-30 1995-01-17 Merck & Co., Inc. Spirocycles
US5475139A (en) * 1993-10-22 1995-12-12 Yung Shin Pharm. Ind. Co., Ltd. Method for the preparation of substituted derivatives of diphenyl amine
US5403846A (en) * 1993-11-22 1995-04-04 Merck & Co., Inc. Spirocycles
US5439914A (en) * 1994-02-18 1995-08-08 Merck & Co., Inc. Spirocycles
FR2717175B1 (fr) * 1994-03-11 1996-06-14 Adir Nouveaux composés alkylaminoindanes, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
US6083986A (en) * 1996-07-26 2000-07-04 Icagen, Inc. Potassium channel inhibitors
US6333337B1 (en) 1998-01-27 2001-12-25 Icagen, Inc. Potassium channel inhibitors
US6632836B1 (en) 1998-10-30 2003-10-14 Merck & Co., Inc. Carbocyclic potassium channel inhibitors
US6303637B1 (en) 1998-10-30 2001-10-16 Merck & Co., Inc. Heterocyclic potassium channel inhibitors
GB9913083D0 (en) 1999-06-04 1999-08-04 Novartis Ag Organic compounds
AU781365B2 (en) 1999-12-21 2005-05-19 Icagen, Inc. Potassium channel inhibitors
DE60113407T2 (de) * 2000-05-04 2006-06-29 Warner-Lambert Co. Llc Verfahren zur hemmung von amyloidprotein aggregation und zur diagnostischen nachweis von amyloidablagerung unter verwendung von aminoindanderivaten
US6566380B2 (en) 2000-07-25 2003-05-20 Icagen, Inc. Potassium channel inhibitors
US6620849B2 (en) 2000-07-26 2003-09-16 Icafen, Inc. Potassium channel inhibitors
US6849634B2 (en) 2000-12-21 2005-02-01 Icagen Potassium channel inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1518652A1 (de) * 1965-05-29 1969-04-10 Albert Ag Chem Werke Verfahren zur Herstellung von pharmazeutisch wirksamen Derivaten des 2-Aminoindans
US3923813A (en) * 1969-12-19 1975-12-02 Christiaens Sa A Derivatives of 2-aminoindanes
EP0164865B1 (de) * 1984-05-04 1988-12-21 The Upjohn Company N-(Aminoalkylphenyl)sulfonamide, ihre Herstellung und ihre therapeutische Verwendung
US4959500A (en) * 1989-05-23 1990-09-25 Ethyl Corporation Polybrominated bis sulfonamides

Also Published As

Publication number Publication date
IE880887L (en) 1988-09-25
JPS63264556A (ja) 1988-11-01
PT87051A (pt) 1988-04-01
EP0286278B1 (de) 1991-01-09
DK160788D0 (da) 1988-03-24
AU593739B2 (en) 1990-02-15
US5006561A (en) 1991-04-09
EP0286278A1 (de) 1988-10-12
PT87051B (pt) 1992-07-31
ATE59842T1 (de) 1991-01-15
IE61071B1 (en) 1994-09-21
DK160788A (da) 1988-12-22
JPH0480019B2 (de) 1992-12-17
ES2036674T3 (es) 1993-06-01
AU1642488A (en) 1989-11-23
GR3001665T3 (en) 1992-11-23
GB8707123D0 (en) 1987-04-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee