DE3854879T2 - Rekombinantes Enzym zur alpha-Amidierung von C-Termini - Google Patents

Rekombinantes Enzym zur alpha-Amidierung von C-Termini

Info

Publication number
DE3854879T2
DE3854879T2 DE3854879T DE3854879T DE3854879T2 DE 3854879 T2 DE3854879 T2 DE 3854879T2 DE 3854879 T DE3854879 T DE 3854879T DE 3854879 T DE3854879 T DE 3854879T DE 3854879 T2 DE3854879 T2 DE 3854879T2
Authority
DE
Germany
Prior art keywords
enzyme
termini
recombinant enzyme
alpha
precursor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3854879T
Other languages
English (en)
Other versions
DE3854879D1 (de
Inventor
Kazuhiro Ohsuye
Katsuhiko Kitano
Shoji Tanaka
Hisayuki Matsuo
Kensaku Mizuno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MATSUO HISAYUKI MINOO OSAKA JP
Asubio Pharma Co Ltd
Original Assignee
MATSUO HISAYUKI MINOO OSAKA JP
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26497821&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3854879(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by MATSUO HISAYUKI MINOO OSAKA JP, Suntory Ltd filed Critical MATSUO HISAYUKI MINOO OSAKA JP
Publication of DE3854879D1 publication Critical patent/DE3854879D1/de
Application granted granted Critical
Publication of DE3854879T2 publication Critical patent/DE3854879T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/17—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced ascorbate as one donor, and incorporation of one atom of oxygen (1.14.17)
    • C12Y114/17003—Peptidylglycine monooxygenase (1.14.17.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE3854879T 1987-07-17 1988-07-15 Rekombinantes Enzym zur alpha-Amidierung von C-Termini Expired - Fee Related DE3854879T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP17718487 1987-07-17
JP62306867A JP2598050B2 (ja) 1987-07-17 1987-12-05 Ｃ−末端α−アミド化酵素

Publications (2)

Publication Number Publication Date
DE3854879D1 DE3854879D1 (de) 1996-02-22
DE3854879T2 true DE3854879T2 (de) 1996-06-13

Family

ID=26497821

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3854879T Expired - Fee Related DE3854879T2 (de) 1987-07-17 1988-07-15 Rekombinantes Enzym zur alpha-Amidierung von C-Termini

Country Status (9)

Country Link
US (3) US6262232B1 (de)
EP (1) EP0299790B1 (de)
JP (1) JP2598050B2 (de)
AT (1) ATE132899T1 (de)
AU (1) AU608027B2 (de)
CA (1) CA1341101C (de)
DE (1) DE3854879T2 (de)
ES (1) ES2081807T3 (de)
GR (1) GR3018650T3 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6319685B1 (en) * 1984-09-27 2001-11-20 Unigene Laboratories, Inc. Alpha-amidating enzyme compositions and processes for their production and use
US5789234A (en) * 1987-08-14 1998-08-04 Unigene Laboratories, Inc. Expression systems for amidating enzyme
US6255067B1 (en) 1987-09-15 2001-07-03 The Johns Hopkins University cDNA encoding peptidyl-glycine alpha-amidating monooxygenase (PAM)
JP2535398B2 (ja) * 1989-01-17 1996-09-18 サントリー株式会社 アミド化ペプチドの製造方法
US5871995A (en) * 1989-08-15 1999-02-16 Shiseido Company, Ltd. Purified enzymes participating in C-terminal amidation
EP0448513A3 (en) * 1990-03-21 1991-12-27 Japat Ltd Process for production of peptidylglycine alpha-hydroxylating monooxygenase and use thereof
ES2079054T3 (es) * 1990-06-01 1996-01-01 Ciba Geigy Ag Peptidilhidroxiglicina n-c-liasa y adn codificante de la misma.
JPH0775593A (ja) * 1993-09-08 1995-03-20 Suntory Ltd 蛋白質の製造方法
JP2650856B2 (ja) * 1994-06-17 1997-09-10 サントリー株式会社 Ｃ−末端アミド化酵素の製造方法
US6528818B1 (en) * 1999-12-14 2003-03-04 Kla-Tencor Test structures and methods for inspection of semiconductor integrated circuits
US20040171167A1 (en) * 2002-12-13 2004-09-02 Affymetrix, Inc. Chip-in-a-well scanning
DE102004058306A1 (de) 2004-12-01 2006-07-27 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Carboxy-terminal amidierten Peptiden
US20080131347A1 (en) * 2006-12-04 2008-06-05 General Electric Company Scintillation compositions and method of manufacture thereof
US20080131348A1 (en) * 2006-12-04 2008-06-05 General Electric Company Scintillation compositions and method of manufacture thereof
JP5401312B2 (ja) 2007-06-29 2014-01-29 第一三共株式会社 組換えＣ−末端α−アミド化酵素誘導体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708934A (en) * 1984-09-27 1987-11-24 Unigene Laboratories, Inc. α-amidation enzyme
JPH0775541B2 (ja) * 1986-06-07 1995-08-16 壽之 松尾 Ｃ末端アミド化酵素及びその製造方法

Also Published As

Publication number Publication date
DE3854879D1 (de) 1996-02-22
AU1910088A (en) 1989-01-19
ATE132899T1 (de) 1996-01-15
US6602681B1 (en) 2003-08-05
EP0299790A2 (de) 1989-01-18
JP2598050B2 (ja) 1997-04-09
GR3018650T3 (en) 1996-04-30
EP0299790B1 (de) 1996-01-10
ES2081807T3 (es) 1996-03-16
US6245887B1 (en) 2001-06-12
US6262232B1 (en) 2001-07-17
EP0299790A3 (en) 1989-03-08
AU608027B2 (en) 1991-03-21
JPH01104168A (ja) 1989-04-21
CA1341101C (en) 2000-09-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: DAIICHI SUNTORY PHARMA CO., LTD., TOKIO/TOKYO, JP

Owner name: MATSUO, HISAYUKI, MINOO, OSAKA, JP

8327 Change in the person/name/address of the patent owner

Owner name: DAIICHI ASUBIO PHARMA CO., LTD., TOKIO/TOKYO, JP

Owner name: MATSUO, HISAYUKI, MINOO, OSAKA, JP

8327 Change in the person/name/address of the patent owner

Owner name: ASUBIO PHARMA CO., LTD., TOKYO, JP

Owner name: MATSUO, HISAYUKI, MINOO, OSAKA, JP

8339 Ceased/non-payment of the annual fee