ES2072893T3 - Endoproteasa kex2 y procedimiento para su produccion. - Google Patents

Endoproteasa kex2 y procedimiento para su produccion.

Info

Publication number
ES2072893T3
ES2072893T3 ES89301051T ES89301051T ES2072893T3 ES 2072893 T3 ES2072893 T3 ES 2072893T3 ES 89301051 T ES89301051 T ES 89301051T ES 89301051 T ES89301051 T ES 89301051T ES 2072893 T3 ES2072893 T3 ES 2072893T3
Authority
ES
Spain
Prior art keywords
kex2 endoprotease
production
dna
production procedure
endoprotease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89301051T
Other languages
English (en)
Inventor
Takehiro Oshima
Kensaku Mizuno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12067048&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2072893(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of ES2072893T3 publication Critical patent/ES2072893T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Mushroom Cultivation (AREA)
  • Game Rules And Presentations Of Slot Machines (AREA)
  • Details Of Garments (AREA)
  • Edible Seaweed (AREA)

Abstract

UNA KEX2 ENDOPROTEASA PRODUCIDA POR UNA TECNICA DE ADN RECOMBINANTE, UNA ENDOPROTEASA KEX2 ACORTADA EN EL C - TERMINAL DE UNA ENCIMA NATIVA Y CONTENIENDO UNA REGION HIDROFOBICA CON C TERMINAL, UNA ENDOPROTEASA KEX2 SOLUBLE SIN UNA REGION HIDROFOBICA CON C - TERMINAL; CODIFICACION DE ADN PARA LAS ENZIMAS ARRIBA MENCIONADAS; PLASMIDOS DE EXPRESION CONTENIENDO EL ADN; HUESPEDES TRANSFORMADOS CON EL PLASMIDO; UN PROCESO PARA PRODUCCION DE LAS ENZIMAS ARRIBA MENCIONADAS UTILIZANDO EL HUESPED TRANSFORMADO; Y UN PROCESO PARA PRODUCCION DE POLIPEPTIDO BIOLOGICAMENTE ACTIVO UTILIZANDO LA ENZIMA MENCIONADA ARRIBA.
ES89301051T 1988-02-03 1989-02-03 Endoproteasa kex2 y procedimiento para su produccion. Expired - Lifetime ES2072893T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63021866A JP2643968B2 (ja) 1988-02-03 1988-02-03 Ｋｅｘ２エンドプロテアーゼ及びその製造方法

Publications (1)

Publication Number Publication Date
ES2072893T3 true ES2072893T3 (es) 1995-08-01

Family

ID=12067048

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89301051T Expired - Lifetime ES2072893T3 (es) 1988-02-03 1989-02-03 Endoproteasa kex2 y procedimiento para su produccion.

Country Status (7)

Country Link
US (1) US5162220A (es)
EP (1) EP0327377B1 (es)
JP (1) JP2643968B2 (es)
AT (1) ATE123520T1 (es)
CA (1) CA1335966C (es)
DE (1) DE68922917T2 (es)
ES (1) ES2072893T3 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2645174B1 (fr) * 1989-03-31 1994-01-07 Transgene Sa Souches de levure ameliorees pour la production de proteines heterologues matures en particulier d'hirudine et procede de preparation d'hirudine correspondant
ES2113878T3 (es) * 1989-12-29 1998-05-16 Zymogenetics Inc Proteina c hibrida.
US5358932A (en) * 1989-12-29 1994-10-25 Zymogenetics, Inc. Hybrid protein C
US5541062A (en) * 1990-02-23 1996-07-30 Arch Development Corporation Methods and compositions for preparing protein processing enzymes
JPH07108232B2 (ja) * 1990-10-09 1995-11-22 エム・ディ・リサーチ株式会社 ペプチド又は蛋白質の製造方法
EP0785273A1 (en) * 1990-11-26 1997-07-23 Genetics Institute, Inc. Paired basic amino acid converting enzyme and DNA sequence encoding it
US5618673A (en) * 1991-08-20 1997-04-08 British Technology Group Limited Oligonucleotides and their use in an assay for encephalopathies
GB9117910D0 (en) * 1991-08-20 1991-10-09 Nat Res Dev Oligonucleotides and their use in an assay
US6348327B1 (en) 1991-12-06 2002-02-19 Genentech, Inc. Non-endocrine animal host cells capable of expressing variant proinsulin and processing the same to form active, mature insulin and methods of culturing such cells
DE69232017T2 (de) * 1991-12-06 2002-03-21 Genentech, Inc. Prohormon Konvertase transformierte Zellen.
DK0548012T3 (da) * 1991-12-16 1998-04-14 Ciba Geigy Ag Endoplasmatisk reticulum-placeret rekombinant dibasisk endoprotease samt dens anvendelse
US5846802A (en) * 1992-04-15 1998-12-08 Buxton; Frank Fungal Protease
US5866351A (en) * 1993-07-07 1999-02-02 University Technology Corporation CD4+ T-lymphocyte proteases and genes encoding said proteases
US5413914A (en) * 1993-07-07 1995-05-09 The Regents Of The University Of Colorado Yeast assay to identify inhibitors of dibasic amino acid processing endoproteases
US5691183A (en) * 1993-07-07 1997-11-25 University Technology Corporation CD4+ T-lymphoctye proteases and genes encoding said proteases
US5981259A (en) * 1993-07-07 1999-11-09 University Technology Corporation CD4+ T-lymphocyte protease genes and inhibitors thereof
CA2198968C (en) * 1996-03-04 2010-02-09 Toyofumi Masuda Process for production of secretory kex2 derivatives
GB9606261D0 (en) * 1996-03-25 1996-05-29 Johnson & Johnson Clin Diag Prenatal screening for fetal abnormalities
CN1226282A (zh) * 1996-06-28 1999-08-18 诺沃挪第克公司 具有齿斑葡聚糖酶活性的重组酶
SK782002A3 (en) 1999-07-21 2003-08-05 Lexigen Pharm Corp FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
CN1300818A (zh) * 1999-12-21 2001-06-27 复旦大学 一种新的多肽－蛋白内切酶Clp12和编码这种多肽的多核苷酸
IT1319659B1 (it) * 2000-11-16 2003-10-23 Norpharma S P A Endoproteasi solubili per il processamento in vitro di proteinericombinanti.
US7348004B2 (en) 2003-05-06 2008-03-25 Syntonix Pharmaceuticals, Inc. Immunoglobulin chimeric monomer-dimer hybrids
TWI353991B (en) * 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
PT1624891E (pt) 2003-05-06 2010-01-05 Syntonix Pharmaceuticals Inc Proteínas quiméricas de factor de coagulação-fc destinadas ao tratamento da hemofilia
AU2004238263A1 (en) * 2003-05-06 2004-11-25 Syntonix Pharmaceuticals, Inc. Inhibition of drug binding to serum albumin
US10180572B2 (en) 2010-02-28 2019-01-15 Microsoft Technology Licensing, Llc AR glasses with event and user action control of external applications
EP2964666B1 (en) 2013-03-06 2020-11-18 GlaxoSmithKline LLC Host cells and methods of use
EA037906B1 (ru) 2013-03-15 2021-06-04 Биовератив Терапьютикс Инк. Препараты полипептида фактора ix
CN106337042B (zh) * 2015-07-16 2019-08-09 上海雅心生物技术有限公司 双碱基酶kex2变体及其高效表达方法

Also Published As

Publication number Publication date
EP0327377B1 (en) 1995-06-07
EP0327377A3 (en) 1990-05-09
ATE123520T1 (de) 1995-06-15
EP0327377A2 (en) 1989-08-09
DE68922917D1 (de) 1995-07-13
JP2643968B2 (ja) 1997-08-25
DE68922917T2 (de) 1995-10-26
JPH01199578A (ja) 1989-08-10
US5162220A (en) 1992-11-10
CA1335966C (en) 1995-06-20

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