DE3787820T2 - Für Flagellin kodierende DNS und dieses enthaltender Vektor. - Google Patents

Für Flagellin kodierende DNS und dieses enthaltender Vektor.

Info

Publication number
DE3787820T2
DE3787820T2 DE87103488T DE3787820T DE3787820T2 DE 3787820 T2 DE3787820 T2 DE 3787820T2 DE 87103488 T DE87103488 T DE 87103488T DE 3787820 T DE3787820 T DE 3787820T DE 3787820 T2 DE3787820 T2 DE 3787820T2
Authority
DE
Germany
Prior art keywords
flagellin
vector containing
dna coding
dna
coding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE87103488T
Other languages
English (en)
Other versions
DE3787820D1 (de
Inventor
Junichiro Asaka
Tamio Fujiwara
Takashi Fujiwara
Goro Kuwajima
Eiji Kondo
Masaru Shin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP61223484A external-priority patent/JP2584213B2/ja
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of DE3787820D1 publication Critical patent/DE3787820D1/de
Application granted granted Critical
Publication of DE3787820T2 publication Critical patent/DE3787820T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE87103488T 1986-03-11 1987-03-11 Für Flagellin kodierende DNS und dieses enthaltender Vektor. Expired - Fee Related DE3787820T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5440086 1986-03-11
JP61223484A JP2584213B2 (ja) 1986-03-11 1986-09-19 フラジエリンをコ−ドするｄｎａおよび該ｄｎａを有するベクタ−

Publications (2)

Publication Number Publication Date
DE3787820D1 DE3787820D1 (de) 1993-11-25
DE3787820T2 true DE3787820T2 (de) 1994-04-28

Family

ID=26395161

Family Applications (1)

Application Number Title Priority Date Filing Date
DE87103488T Expired - Fee Related DE3787820T2 (de) 1986-03-11 1987-03-11 Für Flagellin kodierende DNS und dieses enthaltender Vektor.

Country Status (4)

Country Link
US (1) US4886748A (de)
EP (1) EP0237045B1 (de)
DE (1) DE3787820T2 (de)
ES (1) ES2060580T3 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0241546A4 (de) * 1985-10-11 1988-11-02 Genetics Inst Verfahren zur herstellung heterologer proteine.
US4801536A (en) * 1985-10-11 1989-01-31 Genetics Institute, Inc. Method for producing heterologous proteins
US6130082A (en) * 1988-05-05 2000-10-10 American Cyanamid Company Recombinant flagellin vaccines
DE68922394T2 (de) * 1988-05-05 1995-10-05 Praxis Biolog Inc Rekombinante vakzine von flagellin.
ES2070266T3 (es) * 1989-08-18 1995-06-01 Akzo Nobel Nv Vacuna contra la infeccion por escherichia coli.
US5635182A (en) * 1994-06-16 1997-06-03 Genetics Institute, Inc. Method of detecting ligand interactions
DK1112747T3 (da) * 1999-12-28 2004-10-25 Akzo Nobel Nv Salmonellavaccine, som ikke inducerer antistoffer mod flagellin eller flageller
US20030232055A1 (en) * 2000-07-31 2003-12-18 Ruslan Medzhitov Innate immune system-directed vaccines
US20030175287A1 (en) * 2001-01-03 2003-09-18 Yale University Innate immune system-directed vaccines
AU2005323811B2 (en) * 2004-12-02 2012-07-05 Csir Gram positive bacterial cells comprising a disrupted flagellin gene, flagellin-based fusion proteins and use in removal of metal ions from a liquid
CA2589553C (en) * 2004-12-16 2014-02-18 Wake Forest University Health Sciences Use of flagellin in the immunotherapy of yersinia pestis
ES2555544T3 (es) * 2006-03-07 2016-01-04 Vaxinnate Corporation Composiciones que incluyen hemaglutinina, métodos de preparación y métodos de uso de las mismas
US8020260B2 (en) * 2007-04-16 2011-09-20 Formetco, Inc. Locking clip for a billboard sign tensioning system
EP2349291B1 (de) * 2008-10-03 2012-12-05 Emory University Toll-like-rezeptor-5-agonisten zur behandlung von graft-versus-host-reaktionen
WO2010107778A1 (en) 2009-03-18 2010-09-23 Wake Forest University Health Sciences Flagellin fusion proteins and use thereof to induce immune responses against pseudomonas aeruginosa
US20120135037A1 (en) 2009-06-01 2012-05-31 Mizel Steven B Flagellin fusion proteins and conjugates comprising pneumococcus antigens and methods of using the same
WO2011028875A1 (en) 2009-09-03 2011-03-10 Wake Forest University Health Sciences Immunogenic conjugates for producing immune responses to drugs of abuse and methods of use
ES2690760T3 (es) 2010-06-25 2018-11-22 Inserm - Institut National De La Santé Et De La Recherche Médicale Polipéptido de flagelina como agonista de TLR5 para su uso en el tratamiento de infecciones de las vías respiratorias
WO2015011254A1 (en) 2013-07-26 2015-01-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of bacterial infections
KR102524577B1 (ko) 2019-04-22 2023-04-21 전남대학교산학협력단 플라젤린 융합 단백질 및 이의 용도
FR3114970B1 (fr) 2020-10-08 2023-06-30 Univ Tours Combinaison d’anticorps inhalés avec des agents immunomodulateurs pour le traitement ou la prévention d’inféctions respiratoires
KR102461645B1 (ko) * 2020-10-20 2022-11-01 전남대학교산학협력단 플라젤린 융합 단백질을 포함하는 비알코올성 지방간질환 또는 대사증후군 예방 또는 치료용 조성물
EP4362917A2 (de) 2021-06-30 2024-05-08 Institut National de la Santé et de la Recherche Médicale (INSERM) Aerosolzusammensetzung zur pulmonalen verabreichung von flagellin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0241546A4 (de) * 1985-10-11 1988-11-02 Genetics Inst Verfahren zur herstellung heterologer proteine.

Also Published As

Publication number Publication date
DE3787820D1 (de) 1993-11-25
US4886748A (en) 1989-12-12
EP0237045B1 (de) 1993-10-20
ES2060580T3 (es) 1994-12-01
EP0237045A3 (en) 1988-11-02
EP0237045A2 (de) 1987-09-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee