DE3779999D1 - Erhoehung des penetrationsvermoegens mittels eines aus die zellhuelle veraendernden substanzen und kurzkettigen alkoholen bestehenden binaeren systems. - Google Patents

Erhoehung des penetrationsvermoegens mittels eines aus die zellhuelle veraendernden substanzen und kurzkettigen alkoholen bestehenden binaeren systems.

Info

Publication number
DE3779999D1
DE3779999D1 DE8787116733T DE3779999T DE3779999D1 DE 3779999 D1 DE3779999 D1 DE 3779999D1 DE 8787116733 T DE8787116733 T DE 8787116733T DE 3779999 T DE3779999 T DE 3779999T DE 3779999 D1 DE3779999 D1 DE 3779999D1
Authority
DE
Germany
Prior art keywords
cell
penetration
envelope
hell
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787116733T
Other languages
English (en)
Other versions
DE3779999T2 (de
Inventor
Dinesh C Patel
Yurik Chang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Actavis Laboratories UT Inc
Original Assignee
Theratech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25459727&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3779999(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Theratech Inc filed Critical Theratech Inc
Publication of DE3779999D1 publication Critical patent/DE3779999D1/de
Application granted granted Critical
Publication of DE3779999T2 publication Critical patent/DE3779999T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
DE8787116733T 1986-11-14 1987-11-12 Erhoehung des penetrationsvermoegens mittels eines aus die zellhuelle veraendernden substanzen und kurzkettigen alkoholen bestehenden binaeren systems. Expired - Lifetime DE3779999T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93076486A 1986-11-14 1986-11-14

Publications (2)

Publication Number Publication Date
DE3779999D1 true DE3779999D1 (de) 1992-07-30
DE3779999T2 DE3779999T2 (de) 1992-12-10

Family

ID=25459727

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787116733T Expired - Lifetime DE3779999T2 (de) 1986-11-14 1987-11-12 Erhoehung des penetrationsvermoegens mittels eines aus die zellhuelle veraendernden substanzen und kurzkettigen alkoholen bestehenden binaeren systems.

Country Status (7)

Country Link
EP (1) EP0267617B1 (de)
JP (1) JP2660839B2 (de)
KR (1) KR960001373B1 (de)
AT (1) ATE77559T1 (de)
DE (1) DE3779999T2 (de)
ES (1) ES2042527T3 (de)
GR (1) GR3005030T3 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196410A (en) * 1986-10-31 1993-03-23 Pfizer Inc. Transdermal flux enhancing compositions
US4863738A (en) * 1987-11-23 1989-09-05 Alza Corporation Skin permeation enhancer compositions using glycerol monooleate
US5641504A (en) * 1988-06-09 1997-06-24 Alza Corporation Skin permeation enhancer compositions using glycerol monolinoleate
PT90784A (pt) * 1988-06-09 1989-12-29 Alza Corp Processo para a preparacao de uma composicao de materiais para aplicacao sobre uma superficie corporal ou membral
US4855294A (en) * 1988-09-06 1989-08-08 Theratech, Inc. Method for reducing skin irritation associated with drug/penetration enhancer compositions
US5262164A (en) * 1989-11-17 1993-11-16 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5084267A (en) * 1989-11-17 1992-01-28 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5096715A (en) * 1989-11-20 1992-03-17 Alko Ltd. Method and means for treating alcoholism by extinguishing the alcohol-drinking response using a transdermally administered opiate antagonist
US5374645A (en) * 1990-01-22 1994-12-20 Ciba-Geigy Corporation Transdermal administation of ionic pharmaceutically active agents via aqueous isopropanol
US5149719A (en) * 1990-04-27 1992-09-22 Minnesota Mining And Manufacturing Company Composition for transdermal penetration of medicaments
US5152997A (en) * 1990-12-11 1992-10-06 Theratech, Inc. Method and device for transdermally administering testosterone across nonscrotal skin at therapeutically effective levels
PT100502A (pt) * 1991-05-20 1993-08-31 Alza Corp Composicoes farmaceuticas para aumentar a capacidade de permeacao na pele utilizando monolinoleato de glicerol
WO1994021262A1 (en) * 1993-03-17 1994-09-29 Alza Corporation Device for the transdermal administration of alprazolam
HU214582B (hu) * 1994-07-26 1998-04-28 EGIS Gyógyszergyár Rt. Porlasztható, vérnyomáscsökkentő hatású gyógyszerkészítmény és eljárás előállítására
US5861439A (en) * 1994-11-14 1999-01-19 Alza Corporation Method for enhanced electrotransport agent delivery
EP0742011B1 (de) * 1994-11-17 2002-07-24 Toray Industries, Inc. Transdermal absorbierbare zubereitung
AU4449497A (en) * 1996-10-16 1998-05-11 Ipr-Institute For Pharmaceutical Research Ag New carrier systems
DE69804624T2 (de) * 1997-07-29 2002-09-19 Upjohn Co Selbstemulgierende formulierung enthaltend lipophile verbindungen
WO1999006024A1 (en) * 1997-07-29 1999-02-11 Pharmacia & Upjohn Company Self-emulsifying formulation for lipophilic compounds
JP4139860B2 (ja) 1997-11-10 2008-08-27 ストラカン インターナショナル リミティッド 浸透増強および刺激減少システム
EP1083856A4 (de) * 1998-06-01 2003-09-10 Anthony J Verbiscar Topische transdermale behandlung
US7074803B2 (en) * 2001-03-02 2006-07-11 Durect Corporation Opioid formulations
US7179483B2 (en) 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
IT1318705B1 (it) * 2000-09-22 2003-08-27 Gianluigi Ciocca Medicamento transdermico ad alta penetrazione.
PT1400240E (pt) * 2001-05-31 2010-06-18 Hisamitsu Pharmaceutical Co Pensos de absorção percutânea
GB0300531D0 (en) 2003-01-10 2003-02-12 West Pharm Serv Drug Res Ltd Pharmaceutical compositions
PT1670433E (pt) 2003-10-10 2012-02-08 Ferring Bv Fórmula farmacológica transdérmica para a minimização de resíduos na pele
WO2006125642A1 (en) 2005-05-27 2006-11-30 Antares Pharma Ipl Ag Methods and apparatus for transdermal or transmucosal application of testosterone
CA2646667C (en) 2006-04-21 2014-03-11 Antares Pharma Ipl Ag Methods of treating hot flashes with formulations for transdermal or transmucosal application
FR2905601A1 (fr) * 2006-09-11 2008-03-14 Innoderm Sarl Utilisation de derives oleiques comme methode et composition favorisant la penetration cutanee des actifs contenus dans les compositions cosmetiques, pharmaceutiques ou dermatologiques.
US8927537B2 (en) * 2007-12-21 2015-01-06 Nuvo Research Inc. Patches, formulations, and associated methods for transdermal delivery of alprazolam and other drugs
JP5619363B2 (ja) * 2008-03-03 2014-11-05 ニプロパッチ株式会社 経皮吸収促進剤、並びにこれを含有する皮膚処理用製剤及び経皮吸収型製剤
CN105873587B (zh) * 2013-11-05 2020-07-21 3M创新有限公司 基于芝麻油的注射配制品

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0095813A3 (de) * 1982-06-01 1985-05-08 THE PROCTER & GAMBLE COMPANY Durchdringende topische pharmazeutische Präparate, die 9-(2-Hydroxyäthoxymethyl)-guanin enthalten
DE3233638A1 (de) * 1982-09-10 1984-03-15 Thilo & Co Gmbh Dr Dermatologische zubereitung
US4537776A (en) * 1983-06-21 1985-08-27 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
US4637930A (en) * 1984-02-08 1987-01-20 Yamanouchi Pharmaceutical Co, Ltd. Transdermal formulation of nicardipine hydrochloride
US4626539A (en) * 1984-08-10 1986-12-02 E. I. Dupont De Nemours And Company Trandermal delivery of opioids
JPH0764754B2 (ja) * 1984-10-02 1995-07-12 花王株式会社 経皮吸収促進剤及びこれを含有する皮膚外用剤
JPS6185332A (ja) * 1984-10-04 1986-04-30 Kao Corp 経粘膜吸収促進剤及びこれを含有する経粘膜投与用製剤

Also Published As

Publication number Publication date
ATE77559T1 (de) 1992-07-15
EP0267617B1 (de) 1992-06-24
ES2042527T3 (es) 1993-12-16
JP2660839B2 (ja) 1997-10-08
GR3005030T3 (de) 1993-05-24
KR880005939A (ko) 1988-07-21
KR960001373B1 (ko) 1996-01-26
JPS63211241A (ja) 1988-09-02
EP0267617A1 (de) 1988-05-18
DE3779999T2 (de) 1992-12-10

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