DE3779999D1 - Erhoehung des penetrationsvermoegens mittels eines aus die zellhuelle veraendernden substanzen und kurzkettigen alkoholen bestehenden binaeren systems. - Google Patents

Erhoehung des penetrationsvermoegens mittels eines aus die zellhuelle veraendernden substanzen und kurzkettigen alkoholen bestehenden binaeren systems.

Info

Publication number
DE3779999D1
DE3779999D1 DE8787116733T DE3779999T DE3779999D1 DE 3779999 D1 DE3779999 D1 DE 3779999D1 DE 8787116733 T DE8787116733 T DE 8787116733T DE 3779999 T DE3779999 T DE 3779999T DE 3779999 D1 DE3779999 D1 DE 3779999D1
Authority
DE
Germany
Prior art keywords
cell
penetration
envelope
hell
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787116733T
Other languages
English (en)
Other versions
DE3779999T2 (de
Inventor
Dinesh C Patel
Yurik Chang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Actavis Laboratories UT Inc
Original Assignee
Theratech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25459727&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3779999(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Theratech Inc filed Critical Theratech Inc
Publication of DE3779999D1 publication Critical patent/DE3779999D1/de
Application granted granted Critical
Publication of DE3779999T2 publication Critical patent/DE3779999T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8787116733T 1986-11-14 1987-11-12 Erhoehung des penetrationsvermoegens mittels eines aus die zellhuelle veraendernden substanzen und kurzkettigen alkoholen bestehenden binaeren systems. Expired - Lifetime DE3779999T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93076486A 1986-11-14 1986-11-14

Publications (2)

Publication Number Publication Date
DE3779999D1 true DE3779999D1 (de) 1992-07-30
DE3779999T2 DE3779999T2 (de) 1992-12-10

Family

ID=25459727

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787116733T Expired - Lifetime DE3779999T2 (de) 1986-11-14 1987-11-12 Erhoehung des penetrationsvermoegens mittels eines aus die zellhuelle veraendernden substanzen und kurzkettigen alkoholen bestehenden binaeren systems.

Country Status (7)

Country Link
EP (1) EP0267617B1 (de)
JP (1) JP2660839B2 (de)
KR (1) KR960001373B1 (de)
AT (1) ATE77559T1 (de)
DE (1) DE3779999T2 (de)
ES (1) ES2042527T3 (de)
GR (1) GR3005030T3 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196410A (en) * 1986-10-31 1993-03-23 Pfizer Inc. Transdermal flux enhancing compositions
US4863738A (en) * 1987-11-23 1989-09-05 Alza Corporation Skin permeation enhancer compositions using glycerol monooleate
US5641504A (en) * 1988-06-09 1997-06-24 Alza Corporation Skin permeation enhancer compositions using glycerol monolinoleate
AU611307B2 (en) * 1988-06-09 1991-06-06 Alza Corporation Permeation enhancer comprising ethanol and glycerol monooleate
US4855294A (en) * 1988-09-06 1989-08-08 Theratech, Inc. Method for reducing skin irritation associated with drug/penetration enhancer compositions
US5084267A (en) * 1989-11-17 1992-01-28 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5262164A (en) * 1989-11-17 1993-11-16 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5096715A (en) * 1989-11-20 1992-03-17 Alko Ltd. Method and means for treating alcoholism by extinguishing the alcohol-drinking response using a transdermally administered opiate antagonist
US5374645A (en) * 1990-01-22 1994-12-20 Ciba-Geigy Corporation Transdermal administation of ionic pharmaceutically active agents via aqueous isopropanol
US5149719A (en) * 1990-04-27 1992-09-22 Minnesota Mining And Manufacturing Company Composition for transdermal penetration of medicaments
US5152997A (en) * 1990-12-11 1992-10-06 Theratech, Inc. Method and device for transdermally administering testosterone across nonscrotal skin at therapeutically effective levels
PT100502A (pt) * 1991-05-20 1993-08-31 Alza Corp Composicoes farmaceuticas para aumentar a capacidade de permeacao na pele utilizando monolinoleato de glicerol
AU6410494A (en) * 1993-03-17 1994-10-11 Alza Corporation Device for the transdermal administration of alprazolam
HU214582B (hu) * 1994-07-26 1998-04-28 EGIS Gyógyszergyár Rt. Porlasztható, vérnyomáscsökkentő hatású gyógyszerkészítmény és eljárás előállítására
US5861439A (en) * 1994-11-14 1999-01-19 Alza Corporation Method for enhanced electrotransport agent delivery
CA2181364A1 (en) * 1994-11-17 1996-05-30 Kaneto Uekama Preparation for percutaneous absorption
JP2001502317A (ja) * 1996-10-16 2001-02-20 アイ・ピー・アール・インシティチュート・フォー・ファーマシューティカル・リサーチ・エー・ジー 新規なキャリヤー系
NZ502569A (en) * 1997-07-29 2002-05-31 Upjohn Co Self-emulsifying formulation for lipophilic compounds comprising a mixture of diglyceride and monoglyceride in a ratio of 9:1 to 6:4
JP5005847B2 (ja) * 1997-07-29 2012-08-22 ベーリンガー・インゲルハイム・インテルナツィオナール・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 親油性化合物用の自己乳化性処方
DE69840426D1 (de) * 1997-11-10 2009-02-12 Strakan Int Ltd Penetrationsfördernde und irritationsvermindernde Systeme mit Testosteron
JP2002516828A (ja) * 1998-06-01 2002-06-11 アンソニー・ジェイ・バービスカー 局所経皮治療
US7074803B2 (en) * 2001-03-02 2006-07-11 Durect Corporation Opioid formulations
US7179483B2 (en) 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
IT1318705B1 (it) * 2000-09-22 2003-08-27 Gianluigi Ciocca Medicamento transdermico ad alta penetrazione.
KR20040002890A (ko) * 2001-05-31 2004-01-07 히사미쓰 세이야꾸 가부시키가이샤 경피흡수형 첩부제
GB0300531D0 (en) 2003-01-10 2003-02-12 West Pharm Serv Drug Res Ltd Pharmaceutical compositions
PL1670433T3 (pl) 2003-10-10 2013-03-29 Ferring Bv Przezskórna formulacja farmaceutyczna do zmniejszania pozostałości na skórze
WO2007124250A2 (en) 2006-04-21 2007-11-01 Antares Pharma Ipl Ag Methods of treating hot flashes with formulations for transdermal or transmucosal application
WO2006125642A1 (en) 2005-05-27 2006-11-30 Antares Pharma Ipl Ag Methods and apparatus for transdermal or transmucosal application of testosterone
FR2905601A1 (fr) * 2006-09-11 2008-03-14 Innoderm Sarl Utilisation de derives oleiques comme methode et composition favorisant la penetration cutanee des actifs contenus dans les compositions cosmetiques, pharmaceutiques ou dermatologiques.
US8927537B2 (en) * 2007-12-21 2015-01-06 Nuvo Research Inc. Patches, formulations, and associated methods for transdermal delivery of alprazolam and other drugs
JP5619363B2 (ja) * 2008-03-03 2014-11-05 ニプロパッチ株式会社 経皮吸収促進剤、並びにこれを含有する皮膚処理用製剤及び経皮吸収型製剤
CA2926736C (en) * 2013-11-05 2023-02-28 3M Innovative Properties Company Injectable antineoplastic formilations comprising sesame oil and an immune response modifier

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0095813A3 (de) * 1982-06-01 1985-05-08 THE PROCTER & GAMBLE COMPANY Durchdringende topische pharmazeutische Präparate, die 9-(2-Hydroxyäthoxymethyl)-guanin enthalten
DE3233638A1 (de) * 1982-09-10 1984-03-15 Thilo & Co Gmbh Dr Dermatologische zubereitung
US4537776A (en) * 1983-06-21 1985-08-27 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
US4637930A (en) * 1984-02-08 1987-01-20 Yamanouchi Pharmaceutical Co, Ltd. Transdermal formulation of nicardipine hydrochloride
US4626539A (en) * 1984-08-10 1986-12-02 E. I. Dupont De Nemours And Company Trandermal delivery of opioids
JPH0764754B2 (ja) * 1984-10-02 1995-07-12 花王株式会社 経皮吸収促進剤及びこれを含有する皮膚外用剤
JPS6185332A (ja) * 1984-10-04 1986-04-30 Kao Corp 経粘膜吸収促進剤及びこれを含有する経粘膜投与用製剤

Also Published As

Publication number Publication date
EP0267617B1 (de) 1992-06-24
ES2042527T3 (es) 1993-12-16
GR3005030T3 (de) 1993-05-24
JP2660839B2 (ja) 1997-10-08
EP0267617A1 (de) 1988-05-18
JPS63211241A (ja) 1988-09-02
ATE77559T1 (de) 1992-07-15
KR960001373B1 (ko) 1996-01-26
KR880005939A (ko) 1988-07-21
DE3779999T2 (de) 1992-12-10

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