DE3777223D1 - Feste dispersion der substanz fr-900506. - Google Patents
Feste dispersion der substanz fr-900506.Info
- Publication number
- DE3777223D1 DE3777223D1 DE8787103716T DE3777223T DE3777223D1 DE 3777223 D1 DE3777223 D1 DE 3777223D1 DE 8787103716 T DE8787103716 T DE 8787103716T DE 3777223 T DE3777223 T DE 3777223T DE 3777223 D1 DE3777223 D1 DE 3777223D1
- Authority
- DE
- Germany
- Prior art keywords
- substance
- fixed dispersion
- solid dispersion
- dispersion composition
- octacos
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000006185 dispersion Substances 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 239000007962 solid dispersion Substances 0.000 abstract 2
- CFZGEMKIQUVTCC-UHFFFAOYSA-N octacos-18-ene-2,3,10,16-tetrone Chemical compound CCCCCCCCCC=CCC(=O)CCCCCC(=O)CCCCCCC(=O)C(C)=O CFZGEMKIQUVTCC-UHFFFAOYSA-N 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
- 229920003169 water-soluble polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Reinforced Plastic Materials (AREA)
- Cosmetics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Colloid Chemistry (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868608080A GB8608080D0 (en) | 1986-04-02 | 1986-04-02 | Solid dispersion composition |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3777223D1 true DE3777223D1 (de) | 1992-04-16 |
Family
ID=10595572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8787103716T Expired - Lifetime DE3777223D1 (de) | 1986-04-02 | 1987-03-14 | Feste dispersion der substanz fr-900506. |
Country Status (16)
Families Citing this family (80)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5366971A (en) * | 1987-11-09 | 1994-11-22 | Sandoz Ltd. | Use of 11,28-dioxa-4-azatricyclo[22.3.1.04,9 ]octacos-18-ene derivatives and pharmaceutical compositions containing them |
JPH02206A (ja) * | 1987-11-11 | 1990-01-05 | Fujisawa Pharmaceut Co Ltd | エキシホンと水溶性高分子化合物とを含有することを特徴とする新規製剤 |
EP0315964B1 (en) * | 1987-11-11 | 1993-01-07 | Laboratoires Pharmascience | A novel pharmaceutical composition comprising exifone and water-soluble polymer |
FR2640137A1 (fr) * | 1988-12-08 | 1990-06-15 | Texinfine Sa | Systemes transporteurs de principes actifs lipophiles et leur procede d'obtention |
KR0163035B1 (ko) * | 1989-07-05 | 1998-12-01 | 후지사와 도모키치로 | 외용 수성 액체 조성물 |
US5208228A (en) * | 1989-11-13 | 1993-05-04 | Merck & Co., Inc. | Aminomacrolides and derivatives having immunosuppressive activity |
KR0177158B1 (ko) * | 1990-03-01 | 1999-03-20 | 후지사와 도모기찌로 | 면역억제 활성을 갖는 트리사이클릭 화합물 함유 용액 제제 |
DK0489181T3 (da) * | 1990-07-19 | 1996-11-18 | Otsuka Pharma Co Ltd | Fast præparat |
US5143918A (en) * | 1990-10-11 | 1992-09-01 | Merck & Co., Inc. | Halomacrolides and derivatives having immunosuppressive activity |
US5147877A (en) * | 1991-04-18 | 1992-09-15 | Merck & Co. Inc. | Semi-synthetic immunosuppressive macrolides |
US5565560A (en) * | 1991-05-13 | 1996-10-15 | Merck & Co., Inc. | O-Aryl,O-alkyl,O-alkenyl and O-alkynylmacrolides having immunosuppressive activity |
US5162334A (en) * | 1991-05-13 | 1992-11-10 | Merck & Co., Inc. | Amino O-alkyl, O-alkenyl and O-alkynlmacrolides having immunosuppressive activity |
US5250678A (en) | 1991-05-13 | 1993-10-05 | Merck & Co., Inc. | O-aryl, O-alkyl, O-alkenyl and O-alkynylmacrolides having immunosuppressive activity |
US5189042A (en) * | 1991-08-22 | 1993-02-23 | Merck & Co. Inc. | Fluoromacrolides having immunosuppressive activity |
US5208241A (en) * | 1991-09-09 | 1993-05-04 | Merck & Co., Inc. | N-heteroaryl, n-alkylheteroaryl, n-alkenylheteroaryl and n-alkynylheteroarylmacrolides having immunosuppressive activity |
AU5434094A (en) * | 1992-11-18 | 1994-06-08 | Fujisawa Pharmaceutical Co., Ltd. | Prolonged-action pharmaceutical preparation |
DE4316537A1 (de) * | 1993-05-18 | 1994-11-24 | Basf Ag | Zubereitungen in Form fester Lösungen |
US5693648A (en) * | 1994-09-30 | 1997-12-02 | Merck & Co., Inc. | O-aryl, O-alkyl, O-alkenyl and O-alkynyl-macrolides having immunosuppressive activity |
BE1009856A5 (fr) | 1995-07-14 | 1997-10-07 | Sandoz Sa | Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule. |
JP3266005B2 (ja) | 1995-09-19 | 2002-03-18 | 藤沢薬品工業株式会社 | エアゾール製剤およびその製造方法 |
TW426516B (en) * | 1996-12-06 | 2001-03-21 | Fujisawa Pharmaceutical Co | An oral pharmaceutical composition in solid dispersion containing water-insoluble tricyclic compounds |
EP0978288A4 (en) | 1997-04-11 | 2006-07-12 | Astellas Pharma Inc | DRUG COMPOSITION |
PT1064942E (pt) | 1998-03-26 | 2004-10-29 | Fujisawa Pharmaceutical Co | Preparacao de libertacao sustentada de um macrolido |
US6350786B1 (en) * | 1998-09-22 | 2002-02-26 | Hoffmann-La Roche Inc. | Stable complexes of poorly soluble compounds in ionic polymers |
US6410301B1 (en) | 1998-11-20 | 2002-06-25 | Kosan Biosciences, Inc. | Myxococcus host cells for the production of epothilones |
KR100716272B1 (ko) | 1998-11-20 | 2007-05-09 | 코산 바이오사이언시즈, 인코포레이티드 | 에포틸론 및 에포틸론 유도체의 생산을 위한 재조합 방법 및 물질 |
US20030119029A1 (en) * | 1999-04-30 | 2003-06-26 | Regents Of The University Of Michigan | Compositions and methods relating to novel benzodiazepine compounds and targets thereof |
US20060025388A1 (en) | 1999-04-30 | 2006-02-02 | Glick Gary D | Compositions and methods relating to novel compounds and targets thereof |
PT1143946E (pt) * | 1999-04-30 | 2004-05-31 | Univ Michigan | Utilizacao de benzodiazepinas para tratar doencas autoimunitarias induzidas por apoptose |
US20040176358A1 (en) * | 1999-04-30 | 2004-09-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
US20050113460A1 (en) * | 1999-04-30 | 2005-05-26 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
US7144880B2 (en) * | 1999-04-30 | 2006-12-05 | Regents Of The University Of Michigan | Compositions relating to novel compounds and targets thereof |
US7063857B1 (en) | 1999-04-30 | 2006-06-20 | Sucampo Ag | Use of macrolide compounds for the treatment of dry eye |
US6562795B2 (en) | 2000-02-18 | 2003-05-13 | Kosan Biosciences, Inc. | Motilide compounds |
US6750047B2 (en) * | 2000-08-21 | 2004-06-15 | Kosan Biosciences, Inc. | Fermentation and purification of migrastatin and analog |
GB0108498D0 (en) * | 2001-04-04 | 2001-05-23 | Novartis Ag | Organic Compounds |
JP2004534812A (ja) * | 2001-06-22 | 2004-11-18 | ファイザー・プロダクツ・インク | 薬物および中性ポリマーの分散物の医薬組成物 |
GB0123400D0 (en) | 2001-09-28 | 2001-11-21 | Novartis Ag | Organic compounds |
US6989131B2 (en) * | 2002-03-12 | 2006-01-24 | Uop Llc | Catalytic reactor with integral evaporator |
CA2492846C (en) * | 2002-08-29 | 2012-09-25 | Kosan Biosciences, Inc. | Motilide compounds |
EP1641437A4 (en) * | 2003-07-09 | 2009-06-03 | Chong Kun Dang Pharm Corp | SOLID DISPERSION OF TACROLIMUS |
BRPI0413927B8 (pt) | 2003-08-29 | 2021-05-25 | Lifecycle Pharma As | composição farmacêutica compreendendo tacrolimus, forma de dosagem, uso da composição, e, método para a preparação da composição |
ES2376238T3 (es) | 2003-08-29 | 2012-03-12 | Veloxis Pharmaceuticals A/S | Composiciones de liberación modificada comprendiendo tacrolimus. |
US20090275099A1 (en) * | 2004-04-27 | 2009-11-05 | Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
US20050272723A1 (en) * | 2004-04-27 | 2005-12-08 | The Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
WO2006115509A2 (en) | 2004-06-24 | 2006-11-02 | Novartis Vaccines And Diagnostics Inc. | Small molecule immunopotentiators and assays for their detection |
US20060014677A1 (en) * | 2004-07-19 | 2006-01-19 | Isotechnika International Inc. | Method for maximizing efficacy and predicting and minimizing toxicity of calcineurin inhibitor compounds |
US20060052369A1 (en) * | 2004-09-07 | 2006-03-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
JP2008528448A (ja) * | 2005-01-03 | 2008-07-31 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 新規化合物に関連する組成物および方法、ならびにその標的 |
KR100678824B1 (ko) * | 2005-02-04 | 2007-02-05 | 한미약품 주식회사 | 용해성이 증가된 무정형 타크로리무스 고체분산체 및 이를포함하는 약제학적 조성물 |
US20070043033A1 (en) | 2005-06-01 | 2007-02-22 | The Regents Of The University Of Michigan | Unsolvated benzodiazepine compositions and methods |
US20070105844A1 (en) * | 2005-10-26 | 2007-05-10 | Regents Of The University Of Michigan | Therapeutic compositions and methods |
CA2628193C (en) | 2005-11-01 | 2012-08-14 | The Regents Of The University Of Michigan | Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties |
GB0602632D0 (en) * | 2006-02-08 | 2006-03-22 | Pliva Istrazivacki Inst D O O | Preparation Of A Solid Dosage From Comprising Tacrolimus And/Or Sirolimus |
US7759338B2 (en) * | 2006-04-27 | 2010-07-20 | The Regents Of The University Of Michigan | Soluble 1,4 benzodiazepine compounds and stable salts thereof |
JP5264716B2 (ja) | 2006-06-09 | 2013-08-14 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 化合物およびその標的に関連する組成物および方法 |
US20080181947A1 (en) * | 2006-09-26 | 2008-07-31 | Astellas Pharma Inc. | Controlled release dosage form of tacrolimus |
WO2008084698A1 (ja) | 2006-12-28 | 2008-07-17 | Astellas Pharma Inc. | タクロリムス徐放性医薬組成物 |
MX2009009645A (es) | 2007-03-09 | 2009-11-19 | Univ Michigan | Composiciones y metodos relacionados con nuevos compuestos y objetivos de los mismos. |
US12083103B2 (en) | 2007-05-30 | 2024-09-10 | Veloxis Pharmaceuticals, Inc. | Tacrolimus for improved treatment of transplant patients |
EP2167033B1 (en) | 2007-05-30 | 2017-04-19 | Veloxis Pharmaceuticals A/S | Once daily oral dosage form comprising tacrolimus |
CA2698248C (en) | 2007-09-14 | 2017-08-29 | The Regents Of The University Of Michigan | Phenyl acyl guanidine derivatives as f1f0-atpase inhibitors and the use thereof |
TW200932240A (en) | 2007-10-25 | 2009-08-01 | Astellas Pharma Inc | Pharmaceutical composition containing lipophilic substance which inhibits IL-2 production |
CA2703005A1 (en) | 2007-11-06 | 2009-05-14 | The Regents Of The University Of Michigan | Benzodiazepinone compounds useful in the treatment of skin conditions |
CL2008000374A1 (es) * | 2008-02-05 | 2008-04-04 | Igloo Zone Chile S A | Composicion farmaceutica que comprende un polvo para suspension oral de tacrolimus o una de sus sales, hidratos o solvatos y excipientes farmaceuticamente aceptables; procedimiento de preparacion de dicha composicion farmaceutica; y uso para la preve |
KR101003042B1 (ko) | 2008-03-17 | 2010-12-21 | 종근당바이오 주식회사 | 고순도 타크로리무스의 정제 방법 |
US8222272B2 (en) * | 2008-04-11 | 2012-07-17 | Roxane Laboratories, Inc. | Pharmaceutical formulation and process comprising a solid dispersion of macrolide (tacrolimus) |
US12403095B2 (en) | 2008-05-30 | 2025-09-02 | Veloxis Pharmaceuticals, Inc. | Stabilized tacrolimus composition |
US8497307B2 (en) | 2008-09-11 | 2013-07-30 | The Regents Of The University Of Michigan | Aryl guanidine F1F0-ATPase inhibitors and related methods |
US8604023B2 (en) | 2009-04-17 | 2013-12-10 | The Regents Of The University Of Michigan | 1,4-benzodiazepinone compounds and their use in treating cancer |
JP2013505258A (ja) | 2009-09-18 | 2013-02-14 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | ベンゾジアゼピノン化合物およびそれを使用する治療方法 |
AU2010322287B2 (en) | 2009-11-17 | 2014-04-03 | The Regents Of The University Of Michigan | 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties |
CA2780333C (en) | 2009-11-17 | 2016-05-24 | The Regents Of The University Of Michigan | 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties |
EA027869B1 (ru) | 2010-02-17 | 2017-09-29 | Велоксис Фармасьютикалз А/С | Стабилизированная композиция такролимуса |
PL2579859T3 (pl) | 2010-06-14 | 2015-12-31 | Ratiopharm Gmbh | Kompozycja stała zawierająca iwabradynę |
WO2012026896A1 (en) | 2010-08-25 | 2012-03-01 | Les Laboratoires Medis Sa | Surface modified micronized tacrolimus crystalline particles and pharmaceutical compositions thereof |
KR101243938B1 (ko) * | 2010-10-19 | 2013-03-19 | 이희엽 | 타크롤리무스를 유효성분으로 함유하는 서방형 펠렛 |
JP6185559B2 (ja) * | 2012-04-11 | 2017-08-23 | ダウ グローバル テクノロジーズ エルエルシー | 有機希釈剤およびセルロースエーテルを含む組成物 |
EP3049061B1 (en) * | 2013-09-25 | 2018-06-20 | Dow Global Technologies LLC | Composition comprising an organic liquid diluent and a specific hydroxyalkyl methylcellulose |
CN105828827A (zh) | 2014-11-21 | 2016-08-03 | 杭州领业医药科技有限公司 | 一种含他克莫司的药物组合物及其制备方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL130099C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1963-10-11 | |||
DE1492034A1 (de) * | 1965-05-18 | 1969-02-20 | Merck Ag E | Verfahren zur Herstellung fester haltbarer Zubereitungen von empfindlichen,in Wasser schwer loeslichen Wirkstoffen,vorzugsweise Arzneimitteln |
US3852421A (en) * | 1970-03-23 | 1974-12-03 | Shinetsu Chemical Co | Excipient and shaped medicaments prepared therewith |
GB1322306A (en) * | 1971-04-15 | 1973-07-04 | Meiji Seika Co | Stabilized antibiotic preparation and manufacturing process therefor |
US4127647A (en) * | 1975-04-08 | 1978-11-28 | Meiji Seika Kaisha, Ltd. | Process for preparation of stable amorphous macrolide antibiotic solids |
GB1593261A (en) * | 1976-07-23 | 1981-07-15 | Inveresk Res Int | Controlled release suppository |
GB1579818A (en) * | 1977-06-07 | 1980-11-26 | Yamanouchi Pharma Co Ltd | Nifedipine-containing solid preparation composition |
DE3013839A1 (de) * | 1979-04-13 | 1980-10-30 | Freunt Ind Co Ltd | Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung |
CA1146866A (en) * | 1979-07-05 | 1983-05-24 | Yamanouchi Pharmaceutical Co. Ltd. | Process for the production of sustained release pharmaceutical composition of solid medical material |
US4259314A (en) * | 1979-12-10 | 1981-03-31 | Hans Lowey | Method and composition for the preparation of controlled long-acting pharmaceuticals |
US4369172A (en) * | 1981-12-18 | 1983-01-18 | Forest Laboratories Inc. | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose |
US4389393A (en) * | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
JPS6038322A (ja) * | 1983-08-11 | 1985-02-27 | Fujisawa Pharmaceut Co Ltd | ジヒドロピリジンa物質含有易溶性固形製剤 |
US4894366A (en) * | 1984-12-03 | 1990-01-16 | Fujisawa Pharmaceutical Company, Ltd. | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same |
-
1986
- 1986-04-02 GB GB868608080A patent/GB8608080D0/en active Pending
-
1987
- 1987-03-14 DE DE8787103716T patent/DE3777223D1/de not_active Expired - Lifetime
- 1987-03-14 ES ES198787103716T patent/ES2032397T3/es not_active Expired - Lifetime
- 1987-03-14 AT AT87103716T patent/ATE73327T1/de not_active IP Right Cessation
- 1987-03-14 EP EP87103716A patent/EP0240773B1/en not_active Expired - Lifetime
- 1987-03-18 DK DK198701404A patent/DK174979B1/da not_active IP Right Cessation
- 1987-03-27 JP JP62075470A patent/JPS62277321A/ja active Granted
- 1987-04-01 KR KR1019870003087A patent/KR950007209B1/ko not_active Expired - Lifetime
- 1987-04-01 CA CA000533582A patent/CA1302279C/en not_active Expired - Lifetime
- 1987-04-01 IE IE84387A patent/IE59712B1/en not_active IP Right Cessation
- 1987-04-01 UA UA4202275A patent/UA13209A/uk unknown
- 1987-04-01 RU SU4202275A patent/RU1826977C/ru active
- 1987-07-01 KR KR1019870007053A patent/KR950007210B1/ko not_active Expired - Lifetime
-
1988
- 1988-07-25 US US07/224,235 patent/US4916138A/en not_active Expired - Lifetime
-
1992
- 1992-03-24 GR GR910402151T patent/GR3004124T3/el unknown
- 1992-06-17 MX MX9202945A patent/MX9202945A/es unknown
-
1997
- 1997-01-16 HK HK6397A patent/HK6397A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA1302279C (en) | 1992-06-02 |
KR890001626A (ko) | 1989-03-28 |
DK174979B1 (da) | 2004-04-05 |
DK140487D0 (da) | 1987-03-18 |
UA13209A (uk) | 1997-02-28 |
US4916138A (en) | 1990-04-10 |
EP0240773A1 (en) | 1987-10-14 |
GB8608080D0 (en) | 1986-05-08 |
GR3004124T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-03-31 |
DK140487A (da) | 1987-10-03 |
KR870010073A (ko) | 1987-11-30 |
KR950007210B1 (ko) | 1995-07-04 |
EP0240773B1 (en) | 1992-03-11 |
MX9202945A (es) | 1992-07-01 |
JPS62277321A (ja) | 1987-12-02 |
KR950007209B1 (ko) | 1995-07-04 |
RU1826977C (ru) | 1993-07-07 |
JPH0536411B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-05-31 |
ATE73327T1 (de) | 1992-03-15 |
IE59712B1 (en) | 1994-03-23 |
ES2032397T3 (es) | 1993-02-16 |
IE870843L (en) | 1987-10-02 |
HK6397A (en) | 1997-01-24 |
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