DE3776590D1 - 2-pyridyl-penem-verbindungen. - Google Patents

2-pyridyl-penem-verbindungen.

Info

Publication number
DE3776590D1
DE3776590D1 DE8787810278T DE3776590T DE3776590D1 DE 3776590 D1 DE3776590 D1 DE 3776590D1 DE 8787810278 T DE8787810278 T DE 8787810278T DE 3776590 T DE3776590 T DE 3776590T DE 3776590 D1 DE3776590 D1 DE 3776590D1
Authority
DE
Germany
Prior art keywords
pyridyl
compounds
formula
penem compounds
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787810278T
Other languages
German (de)
English (en)
Inventor
Marc Dr Lang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of DE3776590D1 publication Critical patent/DE3776590D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
DE8787810278T 1986-05-06 1987-04-30 2-pyridyl-penem-verbindungen. Expired - Lifetime DE3776590D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH184686 1986-05-06

Publications (1)

Publication Number Publication Date
DE3776590D1 true DE3776590D1 (de) 1992-03-19

Family

ID=4219979

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787810278T Expired - Lifetime DE3776590D1 (de) 1986-05-06 1987-04-30 2-pyridyl-penem-verbindungen.

Country Status (14)

Country Link
US (1) US4826832A (US07223432-20070529-C00017.png)
EP (1) EP0246187B1 (US07223432-20070529-C00017.png)
JP (1) JPS62263183A (US07223432-20070529-C00017.png)
AT (1) ATE72438T1 (US07223432-20070529-C00017.png)
AU (1) AU603795B2 (US07223432-20070529-C00017.png)
CA (1) CA1293502C (US07223432-20070529-C00017.png)
DE (1) DE3776590D1 (US07223432-20070529-C00017.png)
DK (1) DK169623B1 (US07223432-20070529-C00017.png)
ES (1) ES2038207T3 (US07223432-20070529-C00017.png)
GR (1) GR3003735T3 (US07223432-20070529-C00017.png)
IE (1) IE59714B1 (US07223432-20070529-C00017.png)
NZ (1) NZ220195A (US07223432-20070529-C00017.png)
PT (1) PT84819B (US07223432-20070529-C00017.png)
ZA (1) ZA873198B (US07223432-20070529-C00017.png)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0042026B1 (de) * 1978-02-02 1986-01-08 Ciba-Geigy Ag 3,4-Disubstituierte Azetidin-2-onverbindungen und Verfahren zu ihrer Herstellung
DE3688960D1 (de) * 1985-09-11 1993-10-07 Ciba Geigy Synthese von Beta-Lactamverbindungen.
GB8716679D0 (en) * 1987-07-15 1987-08-19 Erba Farmitalia Penem derivatives
US5492903A (en) * 1990-06-19 1996-02-20 Takeda Chemical Industries Ltd. Crystalline esters of (+)-(5R, 6S)-6-[(R)-1-hydroxyethyl]-3-(3-pyridyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]he
EP0462521A1 (en) * 1990-06-19 1991-12-27 Takeda Chemical Industries, Ltd. Crystalline penem, its production and use
EP0499274A1 (en) * 1991-02-15 1992-08-19 Takeda Chemical Industries, Ltd. Crystalline penem, its production and use
WO1992021304A1 (en) * 1991-06-06 1992-12-10 Cumming Stuart J Intraocular lens with haptic anchor plate
EP0597401A3 (en) * 1992-11-11 1995-07-26 Takeda Chemical Industries Ltd Preparation of penemes.
US20040202714A1 (en) * 1999-10-12 2004-10-14 Daiichi Suntory Pharma Co., Ltd. Oral pharmaceutical composition
DE60008497T2 (de) * 1999-10-12 2004-12-02 Daiichi Suntory Pharma Co., Ltd. Arzneimittel zur oralen verabreichung

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
EP0042026B1 (de) * 1978-02-02 1986-01-08 Ciba-Geigy Ag 3,4-Disubstituierte Azetidin-2-onverbindungen und Verfahren zu ihrer Herstellung
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
US4272437A (en) * 1978-12-18 1981-06-09 Bristol-Myers Company Antibacterial agents, and 4-thio azetidinone intermediates
IL58576A (en) * 1978-12-18 1985-12-31 Bristol Myers Co 2-substituted and 2,6-disubstituted penem compounds,their preparation and pharmaceutical compositions containing them
US4386030A (en) * 1979-12-31 1983-05-31 Merck & Co., Inc. Process for preparing 6-(1'-hydroxyethyl)-2-substituted-pen-2-em-3-carboxylic acid
EP0070204B1 (en) * 1981-07-15 1987-11-19 Sumitomo Pharmaceuticals Company, Limited Carboxylic beta-lactam compounds and the preparation thereof
NZ201471A (en) * 1981-08-10 1985-09-13 Merck & Co Inc Antibacterial compositions containing penems and dipeptidase inhibitors
EP0109362A1 (de) * 1982-11-16 1984-05-23 Ciba-Geigy Ag Heterocyclylverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren
US4540580A (en) * 1982-11-16 1985-09-10 Schering Corporation 2-[(1'R)-1'-Aminoalkyl]penems
DE3366926D1 (en) * 1982-11-16 1986-11-20 Schering Corp Penems, pharmaceutical compositions containing them, process for preparing them
EP0148128A3 (de) * 1983-12-30 1985-08-07 Ciba-Geigy Ag Neue optisch aktive Penem-Verbindungen
GB8416652D0 (en) * 1984-06-29 1984-08-01 Erba Farmitalia Penem derivatives
US4617300A (en) * 1984-09-21 1986-10-14 Schering Corporation 2(N-heterocyclyl) penems
EP0199675A1 (de) * 1985-04-17 1986-10-29 Ciba-Geigy Ag Heterocyclyl-penem-Verbindungen

Also Published As

Publication number Publication date
PT84819A (en) 1987-06-01
IE871182L (en) 1987-11-06
NZ220195A (en) 1989-01-06
PT84819B (pt) 1989-12-29
AU7251287A (en) 1987-11-12
DK228687A (da) 1987-11-07
ATE72438T1 (de) 1992-02-15
US4826832A (en) 1989-05-02
JPS62263183A (ja) 1987-11-16
IE59714B1 (en) 1994-03-23
CA1293502C (en) 1991-12-24
EP0246187A2 (de) 1987-11-19
ZA873198B (en) 1987-12-30
DK228687D0 (da) 1987-05-05
JPH0339514B2 (US07223432-20070529-C00017.png) 1991-06-14
EP0246187A3 (en) 1988-03-16
ES2038207T3 (es) 1993-07-16
DK169623B1 (da) 1994-12-27
EP0246187B1 (de) 1992-02-05
AU603795B2 (en) 1990-11-29
GR3003735T3 (US07223432-20070529-C00017.png) 1993-03-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS AG, BASEL, CH