ATE27818T1 - Pyrimidonderivate. - Google Patents

Pyrimidonderivate.

Info

Publication number
ATE27818T1
ATE27818T1 AT84304870T AT84304870T ATE27818T1 AT E27818 T1 ATE27818 T1 AT E27818T1 AT 84304870 T AT84304870 T AT 84304870T AT 84304870 T AT84304870 T AT 84304870T AT E27818 T1 ATE27818 T1 AT E27818T1
Authority
AT
Austria
Prior art keywords
pyridyl
oxo
methyl
dimethyl
hydroxymethyl
Prior art date
Application number
AT84304870T
Other languages
English (en)
Inventor
George Sidney Sach
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Application granted granted Critical
Publication of ATE27818T1 publication Critical patent/ATE27818T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing alicyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
AT84304870T 1983-07-23 1984-07-17 Pyrimidonderivate. ATE27818T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838319874A GB8319874D0 (en) 1983-07-23 1983-07-23 Compounds
EP84304870A EP0134091B1 (de) 1983-07-23 1984-07-17 Pyrimidonderivate

Publications (1)

Publication Number Publication Date
ATE27818T1 true ATE27818T1 (de) 1987-07-15

Family

ID=10546171

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84304870T ATE27818T1 (de) 1983-07-23 1984-07-17 Pyrimidonderivate.

Country Status (23)

Country Link
US (1) US4665078A (de)
EP (1) EP0134091B1 (de)
JP (1) JPS6048986A (de)
KR (1) KR850001194A (de)
AT (1) ATE27818T1 (de)
AU (1) AU3080984A (de)
CS (1) CS244446B2 (de)
DD (1) DD216463A5 (de)
DE (1) DE3464249D1 (de)
DK (1) DK359184A (de)
ES (1) ES8602761A1 (de)
FI (1) FI842907A (de)
GB (1) GB8319874D0 (de)
GR (1) GR79961B (de)
HU (1) HUT34745A (de)
IL (1) IL72448A0 (de)
JO (1) JO1326B1 (de)
NO (1) NO842963L (de)
NZ (1) NZ208956A (de)
PL (1) PL248859A1 (de)
PT (1) PT78961A (de)
RO (1) RO89219A (de)
ZA (1) ZA845622B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT78358B (en) * 1983-04-07 1986-05-30 Smith Kline French Lab Chemical process
US7045519B2 (en) 1998-06-19 2006-05-16 Chiron Corporation Inhibitors of glycogen synthase kinase 3
JP4533534B2 (ja) 1998-06-19 2010-09-01 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド グリコーゲンシンターゼキナーゼ３のインヒビター
US10596401B2 (en) 2016-08-11 2020-03-24 Victaulic Company Modular valve assembly
US20180193681A1 (en) 2017-01-06 2018-07-12 Globe Fire Sprinkler Corporation Control valve assembly with test, drain and adjustable pressure relief valve
CN112219050B (zh) 2018-03-29 2022-12-30 维特利公司 用于湿式喷淋灭火系统的集合控制和止回功能的阀门总成
EP4031788A4 (de) 2019-09-20 2023-10-18 Victaulic Company Kugelventilanordnung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4154834A (en) * 1975-12-29 1979-05-15 Smith Kline & French Laboratories Limited Substituted isocytosines having histamine H2 -antagonist activity
IN151188B (de) * 1978-02-13 1983-03-05 Smith Kline French Lab
ZW21281A1 (en) * 1980-10-01 1981-11-18 Smith Kline French Lab Amine derivatives
PT75074B (en) * 1981-06-27 1986-02-26 Smith Kline French Lab Process for preparing certain pyrimidone derivatives and compositions containing them

Also Published As

Publication number Publication date
DK359184D0 (da) 1984-07-20
IL72448A0 (en) 1984-11-30
ES534452A0 (es) 1985-12-01
HUT34745A (en) 1985-04-28
JPS6048986A (ja) 1985-03-16
CS244446B2 (en) 1986-07-17
NO842963L (no) 1985-01-24
EP0134091A1 (de) 1985-03-13
KR850001194A (ko) 1985-03-16
FI842907A0 (fi) 1984-07-19
DK359184A (da) 1985-01-24
GR79961B (de) 1984-10-31
PT78961A (en) 1984-08-01
FI842907A (fi) 1985-01-24
DD216463A5 (de) 1984-12-12
US4665078A (en) 1987-05-12
ES8602761A1 (es) 1985-12-01
DE3464249D1 (de) 1987-07-23
ZA845622B (en) 1985-07-31
EP0134091B1 (de) 1987-06-16
GB8319874D0 (en) 1983-08-24
PL248859A1 (en) 1985-07-16
NZ208956A (en) 1987-03-06
CS557184A2 (en) 1985-08-15
JO1326B1 (en) 1986-11-30
AU3080984A (en) 1985-01-24
RO89219A (ro) 1986-03-15

Similar Documents

Publication Publication Date Title
ES513469A0 (es) Procedimiento para preparar derivados de pirimidona.
ATE27818T1 (de) Pyrimidonderivate.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties