DE377229C - Process for the preparation of a clearly soluble dry salt mixture containing the total salts of the blood serum - Google Patents

Process for the preparation of a clearly soluble dry salt mixture containing the total salts of the blood serum

Info

Publication number
DE377229C
DE377229C DES60834D DES0060834D DE377229C DE 377229 C DE377229 C DE 377229C DE S60834 D DES60834 D DE S60834D DE S0060834 D DES0060834 D DE S0060834D DE 377229 C DE377229 C DE 377229C
Authority
DE
Germany
Prior art keywords
blood serum
mixture containing
preparation
salt mixture
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DES60834D
Other languages
German (de)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals Dresden
Original Assignee
Saechsisches Serumwerk Dresden
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Saechsisches Serumwerk Dresden filed Critical Saechsisches Serumwerk Dresden
Priority to DES60834D priority Critical patent/DE377229C/en
Application granted granted Critical
Publication of DE377229C publication Critical patent/DE377229C/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

Verfahren zur Herstellung einer die Gesamtsalze des Blutserums enthaltenden und klar löslichen trockenen Salzmischung. Das Zusatzpatent 339052 zum Hauptpatent 329309 nach welchem ein Lösungsverzug durch Additionsverbindungen des Ca Cl" mit Aminosäuren, z. B. Glykokoll, erreicht wird, ist insofern zu erweitern, als man an deren Stelle in Wasser vollständig lösliche Kalziumsalze organischer Säuren, die in wässeriger Lösung sehr wenig dissoniert sind, anwendet, z. B. das neutrale Kalziumsalz der Milchsäure (C2 H4 O H C O O)2 Ca -j- 5 H2 O. Setzt man zu einer mit derartigem Salze hergestellten Lösung Ammoniumoxalat, so erfolgt ein Niederschlag von Kalziumoxalat erst nach einiger Zeit. Diese Verzögerung ist nun ausreichend, um die Bildung des unlöslichen Kalziumphosphats bzw. -karbonats beim Auflösen einer Mischung der Restsalze mit einem derartigen Kalziumsalz in Wasser vollständig zu verhindern.Process for the preparation of one containing the total salts of the blood serum and clear soluble dry salt mixture. The additional patent 339052 to the main patent 329309 after which a solution delay through addition compounds of Ca Cl "with Amino acids, e.g. B. glycocolla, is to be expanded insofar as one instead of these, calcium salts of organic acids which are completely soluble in water, which are very little dissonated in aqueous solution, applies e.g. B. the neutral Calcium salt of lactic acid (C2 H4 O H C O O) 2 Ca -j- 5 H2 O. One sets to one A solution of ammonium oxalate prepared with such salts results in a precipitate calcium oxalate takes some time. This delay is now sufficient about the formation of insoluble calcium phosphate or carbonate when dissolving a Mix the residual salts with such a calcium salt in water completely impede.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung einer die Gesamtsalze des Blutserums enthaltenden und klar löslichen trockenen Salzmischung, nach Patent 329309 und Zusatzpatent 339052, dadurch gekennzeichnet, daB man statt Additionsverbindungen des Kalziumchlorids mit Aminosäuren lösliche Kalziumsalze von in wässeriger Lösung sehr wenig dissonierten organischen Säuren der Mischung der Restsalze zusetzt. PATENT CLAIM: Process for the production of a clearly soluble dry salt mixture containing the total salts of the blood serum, according to patent 329309 and additional patent 339052, characterized in that instead of addition compounds of calcium chloride with amino acids, soluble calcium salts of organic acids which are very little dissonated in aqueous solution are used in the mixture of residual salts clogs.
DES60834D 1922-09-12 1922-09-12 Process for the preparation of a clearly soluble dry salt mixture containing the total salts of the blood serum Expired DE377229C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DES60834D DE377229C (en) 1922-09-12 1922-09-12 Process for the preparation of a clearly soluble dry salt mixture containing the total salts of the blood serum

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DES60834D DE377229C (en) 1922-09-12 1922-09-12 Process for the preparation of a clearly soluble dry salt mixture containing the total salts of the blood serum

Publications (1)

Publication Number Publication Date
DE377229C true DE377229C (en) 1923-06-14

Family

ID=7494405

Family Applications (1)

Application Number Title Priority Date Filing Date
DES60834D Expired DE377229C (en) 1922-09-12 1922-09-12 Process for the preparation of a clearly soluble dry salt mixture containing the total salts of the blood serum

Country Status (1)

Country Link
DE (1) DE377229C (en)

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