DE3690457T1 - - Google Patents

Info

Publication number
DE3690457T1
DE3690457T1 DE19863690457 DE3690457T DE3690457T1 DE 3690457 T1 DE3690457 T1 DE 3690457T1 DE 19863690457 DE19863690457 DE 19863690457 DE 3690457 T DE3690457 T DE 3690457T DE 3690457 T1 DE3690457 T1 DE 3690457T1
Authority
DE
Germany
Prior art keywords
hydroxydihydronormorphine
desoxy
cyclopropylmethyl
methylene
injection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19863690457
Other languages
German (de)
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Branded Pharmaceutical Products R&D Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of DE3690457T1 publication Critical patent/DE3690457T1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE19863690457 1985-09-06 1986-09-08 Withdrawn DE3690457T1 (OSRAM)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77321385A 1985-09-06 1985-09-06

Publications (1)

Publication Number Publication Date
DE3690457T1 true DE3690457T1 (OSRAM) 1987-08-06

Family

ID=25097554

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19863690457 Withdrawn DE3690457T1 (OSRAM) 1985-09-06 1986-09-08
DE8686906052T Expired - Lifetime DE3687575T2 (de) 1985-09-06 1986-09-08 Verwendung von 6-methylen-6-desoxy-n-cyclopropylmethyl-14-hydroxydihydronormorphin.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8686906052T Expired - Lifetime DE3687575T2 (de) 1985-09-06 1986-09-08 Verwendung von 6-methylen-6-desoxy-n-cyclopropylmethyl-14-hydroxydihydronormorphin.

Country Status (5)

Country Link
EP (1) EP0236477B1 (OSRAM)
JP (1) JPS63500799A (OSRAM)
AT (1) ATE84717T1 (OSRAM)
DE (2) DE3690457T1 (OSRAM)
WO (1) WO1987001282A2 (OSRAM)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1685839E (pt) 1997-12-22 2013-07-08 Euro Celtique Sa Forma de dosagem farmacêutica por via oral compreendendo uma combinação de um agonista opióide e de um antagonista opióide
WO2001058447A1 (en) 2000-02-08 2001-08-16 Euro-Celtique, S.A. Controlled-release compositions containing opioid agonist and antagonist
DE60238756D1 (de) 2001-05-11 2011-02-10 Endo Pharmaceuticals Inc Opioid enthaltende arzneiform gegen missbrauch
ES2326794T3 (es) 2001-08-06 2009-10-20 Euro-Celtique S.A. Formulaciones de agonistas opioides con antagonista liberable y secuestrado.
PT2425824T (pt) 2002-04-05 2017-08-23 Mundipharma Farmacêutica Lda Preparação farmacêutica contendo oxicodona e naloxona
US7815934B2 (en) 2002-09-20 2010-10-19 Alpharma Pharmaceuticals, Llc Sequestering subunit and related compositions and methods
MY135852A (en) 2003-04-21 2008-07-31 Euro Celtique Sa Pharmaceutical products
EP1702558A1 (en) 2005-02-28 2006-09-20 Euro-Celtique S.A. Method and device for the assessment of bowel function
PT2484346T (pt) 2006-06-19 2017-04-26 Alpharma Pharmaceuticals Llc Composições farmacêuticas
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
ME03298B (me) 2009-03-10 2019-07-20 Euro Celtique Sa Farmaceutske kombinacije sa trenutnim oslobađanjem које obuhvataju oksikodon i nalokson
CN105517551A (zh) 2013-07-23 2016-04-20 欧洲凯尔特公司 用于在患有疼痛和导致肠生态失调和/或提高肠细菌移位风险之疾病的患者中治疗疼痛的羟考酮与纳洛酮的组合

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB769517A (en) * 1953-10-20 1957-03-06 Merck & Co Inc Analgesic compositions
US3493657A (en) * 1961-03-14 1970-02-03 Mozes Juda Lewenstein Therapeutic compositions of n-allyl-14-hydroxy - dihydronormorphinane and morphine
US3814768A (en) * 1971-11-26 1974-06-04 Lewenstein E 6-methylene-6-desoxy dihydro morphine and codeine derivatives and pharmaceutically acceptable salts
US4322426A (en) * 1980-04-28 1982-03-30 E. I. Du Pont De Nemours And Company 17-Substituted-6-desoxy-7,8-dihydro-6α-methylnoroxymorphone narcotic antagonists
WO1983003197A1 (en) * 1982-03-16 1983-09-29 Univ Rockefeller Method for controlling gastrointestinal dysmotility
US4567185A (en) * 1983-05-13 1986-01-28 Key Pharmaceuticals, Inc. Endorphin blockage
US4535157A (en) * 1983-11-01 1985-08-13 Key Pharmaceuticals, Inc. Process for making 6-desoxy-6-methylenenaloxone and 6-desoxy-6-methylenenaltrexone
GB8332556D0 (en) * 1983-12-06 1984-01-11 Reckitt & Colmann Prod Ltd Analgesic compositions

Also Published As

Publication number Publication date
JPS63500799A (ja) 1988-03-24
ATE84717T1 (de) 1993-02-15
WO1987001282A2 (en) 1987-03-12
WO1987001282A3 (en) 1987-08-13
DE3687575T2 (de) 1993-07-01
DE3687575D1 (de) 1993-03-04
EP0236477A1 (en) 1987-09-16
EP0236477B1 (en) 1993-01-20

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: IVAX LABORATORIES INC., MIAMI, FLA., US

8128 New person/name/address of the agent

Representative=s name: SCHOENWALD, K., DR.-ING. VON KREISLER, A., DIPL.-C

8127 New person/name/address of the applicant

Owner name: BAKER CUMMINS PHARMACEUTICALS, INC., MIAMI, FLA.,

8139 Disposal/non-payment of the annual fee