DE3686981T2 - Produktion eines proteins. - Google Patents

Produktion eines proteins.

Info

Publication number
DE3686981T2
DE3686981T2 DE8686302833T DE3686981T DE3686981T2 DE 3686981 T2 DE3686981 T2 DE 3686981T2 DE 8686302833 T DE8686302833 T DE 8686302833T DE 3686981 T DE3686981 T DE 3686981T DE 3686981 T2 DE3686981 T2 DE 3686981T2
Authority
DE
Germany
Prior art keywords
protein
escherichia coli
ion source
start codon
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686302833T
Other languages
English (en)
Other versions
DE3686981D1 (de
Inventor
Kazuaki Kitano
Shigeru Fujimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1985/000248 external-priority patent/WO1986006410A1/ja
Priority claimed from JP61045667A external-priority patent/JPH0634746B2/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE3686981D1 publication Critical patent/DE3686981D1/de
Publication of DE3686981T2 publication Critical patent/DE3686981T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE8686302833T 1985-04-30 1986-04-16 Produktion eines proteins. Expired - Fee Related DE3686981T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/JP1985/000248 WO1986006410A1 (en) 1985-04-30 1985-04-30 Process for increasing yield of interleukin-2
JP22151785 1985-10-03
JP61045667A JPH0634746B2 (ja) 1985-04-30 1986-03-03 インターロイキンの増収法

Publications (2)

Publication Number Publication Date
DE3686981D1 DE3686981D1 (de) 1992-11-26
DE3686981T2 true DE3686981T2 (de) 1993-07-08

Family

ID=27292335

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686302833T Expired - Fee Related DE3686981T2 (de) 1985-04-30 1986-04-16 Produktion eines proteins.

Country Status (10)

Country Link
EP (1) EP0200417B1 (de)
CN (1) CN1012645B (de)
AT (1) ATE81675T1 (de)
AU (1) AU603545B2 (de)
CA (1) CA1273591A (de)
DE (1) DE3686981T2 (de)
DK (1) DK196086A (de)
IE (1) IE58766B1 (de)
IL (1) IL78543A (de)
NZ (1) NZ215994A (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3532134A1 (de) * 1985-09-10 1987-03-12 Basf Ag Verfahren zur herstellung von proteinen bestimmter n-terminaler struktur mit hilfe von prokaryonten
EP0315950A3 (de) * 1987-11-09 1990-05-23 Otsuka Pharmaceutical Co., Ltd. Verfahren zur Züchtung von Zellen, welche rekombinantes Protein exprimieren
CN1062311C (zh) * 1996-12-27 2001-02-21 中国医学科学院基础医学研究所 人白细胞介素2衍生物与人心钠素衍生物的融合基因、其蛋白产物及应用
DE19749259A1 (de) * 1997-11-07 1999-05-12 Dade Behring Marburg Gmbh Verfahren zur Herstellung von funktionalem rekombinantem Gewebsfaktor
CN102643826A (zh) * 2012-04-10 2012-08-22 上海交通大学 胸腺素β4四联体基因及其在大肠杆菌中表达的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2108510B (en) * 1981-10-03 1984-12-12 Ciba Geigy Ag Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof
JPS60118196A (ja) * 1983-11-30 1985-06-25 Takeda Chem Ind Ltd インタ−フェロンの製造法
US4855238A (en) * 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
US4656132A (en) * 1984-03-28 1987-04-07 Cetus Corporation Method of improving the yield of heterologous protein produced by cultivating recombinant bacteria
DE3532134A1 (de) * 1985-09-10 1987-03-12 Basf Ag Verfahren zur herstellung von proteinen bestimmter n-terminaler struktur mit hilfe von prokaryonten

Also Published As

Publication number Publication date
AU603545B2 (en) 1990-11-22
CA1273591A (en) 1990-09-04
EP0200417A3 (en) 1988-08-31
IL78543A0 (en) 1986-08-31
NZ215994A (en) 1989-07-27
IE58766B1 (en) 1993-11-03
DK196086D0 (da) 1986-04-29
CN1012645B (zh) 1991-05-22
EP0200417A2 (de) 1986-11-05
CN86102977A (zh) 1986-10-29
IE860997L (en) 1986-10-30
EP0200417B1 (de) 1992-10-21
DE3686981D1 (de) 1992-11-26
DK196086A (da) 1986-10-31
IL78543A (en) 1994-11-28
AU5652286A (en) 1986-11-06
ATE81675T1 (de) 1992-11-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee