DE3686909D1 - Lymphotoxin-dns, lymphotoxin-expressionsvektor, lymphotoxin-expressionsvektor enthaltender transformant und verfahren zur herstellung von lymphotoxin. - Google Patents

Lymphotoxin-dns, lymphotoxin-expressionsvektor, lymphotoxin-expressionsvektor enthaltender transformant und verfahren zur herstellung von lymphotoxin.

Info

Publication number
DE3686909D1
DE3686909D1 DE8686109069T DE3686909T DE3686909D1 DE 3686909 D1 DE3686909 D1 DE 3686909D1 DE 8686109069 T DE8686109069 T DE 8686109069T DE 3686909 T DE3686909 T DE 3686909T DE 3686909 D1 DE3686909 D1 DE 3686909D1
Authority
DE
Germany
Prior art keywords
lymphotoxin
expression vector
dna
producing
vector containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686109069T
Other languages
English (en)
Other versions
DE3686909T2 (de
Inventor
Tetsu Kakutani
Kenji Yamashita
Yasuhiro Ikenaka
Hajime Kawaharada
Kiyoshi Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP60147371A external-priority patent/JPH0834725B2/ja
Priority claimed from JP60230744A external-priority patent/JPS62111928A/ja
Priority claimed from JP61023637A external-priority patent/JPS62181779A/ja
Priority claimed from JP61034962A external-priority patent/JPS62195285A/ja
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Publication of DE3686909D1 publication Critical patent/DE3686909D1/de
Application granted granted Critical
Publication of DE3686909T2 publication Critical patent/DE3686909T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE8686109069T 1985-07-04 1986-07-03 Lymphotoxin-dns, lymphotoxin-expressionsvektor, lymphotoxin-expressionsvektor enthaltender transformant und verfahren zur herstellung von lymphotoxin. Expired - Fee Related DE3686909T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP60147371A JPH0834725B2 (ja) 1985-07-04 1985-07-04 リンホトキシン
JP60230744A JPS62111928A (ja) 1985-10-15 1985-10-15 新規リンホトキシン
JP61023637A JPS62181779A (ja) 1986-02-05 1986-02-05 リンホトキシン耐性細胞及び該細胞を用いるリンホトキシンの製造方法
JP61034962A JPS62195285A (ja) 1986-02-19 1986-02-19 リンホトキシン発現ベクタ−及びそれを用いるリンホトキシンの製造方法

Publications (2)

Publication Number Publication Date
DE3686909D1 true DE3686909D1 (de) 1992-11-12
DE3686909T2 DE3686909T2 (de) 1993-02-18

Family

ID=27458011

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686109069T Expired - Fee Related DE3686909T2 (de) 1985-07-04 1986-07-03 Lymphotoxin-dns, lymphotoxin-expressionsvektor, lymphotoxin-expressionsvektor enthaltender transformant und verfahren zur herstellung von lymphotoxin.

Country Status (5)

Country Link
US (1) US4988624A (de)
EP (1) EP0207518B1 (de)
AU (1) AU603768B2 (de)
CA (1) CA1302921C (de)
DE (1) DE3686909T2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341423C (en) * 1984-10-31 2003-03-04 Paul A. Luciw Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome
US4775624A (en) * 1985-02-08 1988-10-04 Eli Lilly And Company Vectors and compounds for expression of human protein C
DE3620656A1 (de) * 1986-06-20 1987-12-23 Basf Ag Polypeptide mit lymphotoxin-aktivitaet oder lymphotoxin-aehnlicher aktivitaet, ihre herstellung und verwendung
ZA875681B (en) * 1986-08-01 1988-04-27 Commw Scient Ind Res Org Recombinant vaccine
US5175268A (en) * 1986-12-24 1992-12-29 Takeda Chemical Industries, Ltd. DNA encoding recombinant human lymphotoxin
JPS6463395A (en) * 1987-05-04 1989-03-09 Oncogen Oncostatin m and novel composition having antitumor activity
GB2217326B (en) * 1988-04-08 1991-11-20 British Bio Technology Synthetic gene encoding human tumour necrosis factor beta.
AU2003291625B2 (en) * 2002-09-16 2009-10-08 Genentech, Inc. Compositions and methods for the treatment of immune related diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4727028A (en) * 1981-06-22 1988-02-23 Eli Lilly And Company Recombinant DNA cloning vectors and the eukaryotic and prokaryotic transformants thereof
US4740461A (en) * 1983-12-27 1988-04-26 Genetics Institute, Inc. Vectors and methods for transformation of eucaryotic cells
NZ212207A (en) * 1984-05-31 1991-07-26 Genentech Inc Recombinant lymphotoxin

Also Published As

Publication number Publication date
AU603768B2 (en) 1990-11-29
US4988624A (en) 1991-01-29
EP0207518A2 (de) 1987-01-07
AU5945386A (en) 1987-01-08
EP0207518A3 (en) 1988-05-04
DE3686909T2 (de) 1993-02-18
EP0207518B1 (de) 1992-10-07
CA1302921C (en) 1992-06-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee