DE3686897T2 - Arzneimittelabgabesystem mit kontrolliertem ph-wert. - Google Patents

Arzneimittelabgabesystem mit kontrolliertem ph-wert.

Info

Publication number
DE3686897T2
DE3686897T2 DE8686104532T DE3686897T DE3686897T2 DE 3686897 T2 DE3686897 T2 DE 3686897T2 DE 8686104532 T DE8686104532 T DE 8686104532T DE 3686897 T DE3686897 T DE 3686897T DE 3686897 T2 DE3686897 T2 DE 3686897T2
Authority
DE
Germany
Prior art keywords
controlled
value
delivery system
drug delivery
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686104532T
Other languages
English (en)
Other versions
DE3686897D1 (de
Inventor
Joseph V Bondi
Alice E Loper
Edward M Cohen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE3686897D1 publication Critical patent/DE3686897D1/de
Application granted granted Critical
Publication of DE3686897T2 publication Critical patent/DE3686897T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
DE8686104532T 1985-04-05 1986-04-03 Arzneimittelabgabesystem mit kontrolliertem ph-wert. Expired - Fee Related DE3686897T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72065285A 1985-04-05 1985-04-05

Publications (2)

Publication Number Publication Date
DE3686897D1 DE3686897D1 (de) 1992-11-12
DE3686897T2 true DE3686897T2 (de) 1993-04-15

Family

ID=24894807

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686104532T Expired - Fee Related DE3686897T2 (de) 1985-04-05 1986-04-03 Arzneimittelabgabesystem mit kontrolliertem ph-wert.

Country Status (5)

Country Link
US (1) US4756710A (de)
EP (1) EP0197504B1 (de)
JP (1) JPS61275213A (de)
CA (1) CA1272954A (de)
DE (1) DE3686897T2 (de)

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US5407685A (en) * 1986-02-06 1995-04-18 Steris Corporation Controlled oxygen/anti-microbial release films
US4797284A (en) * 1986-03-12 1989-01-10 Merck & Co., Inc. Transdermal drug delivery system
US4917895A (en) * 1987-11-02 1990-04-17 Alza Corporation Transdermal drug delivery device
US4837027A (en) * 1987-11-09 1989-06-06 Alza Corporation Transdermal drug delivery device
US4781924A (en) * 1987-11-09 1988-11-01 Alza Corporation Transdermal drug delivery device
GB8804164D0 (en) * 1988-02-23 1988-03-23 Tucker J M Bandage for administering physiologically active compound
GB2232892B (en) * 1988-02-23 1991-07-24 John Mark Tucker Occlusive body for administering a physiologically active substance
FI82240C (fi) * 1988-10-20 1991-02-11 Huhtamaeki Oy Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.
US5057072A (en) * 1988-10-28 1991-10-15 Medtronic, Inc. Iontophoresis electrode
CA2001444C (en) * 1988-10-28 2000-07-25 Darrel F. Untereker Iontophoresis electrode
US5008110A (en) * 1988-11-10 1991-04-16 The Procter & Gamble Company Storage-stable transdermal patch
DE3905050A1 (de) * 1989-02-18 1990-08-30 Lohmann Therapie Syst Lts Therapeutisches system zur verzoegerten und gesteuerten transdermalen oder transmucosalen verabreichung von wirkstoffen (ii)
DE3905051A1 (de) * 1989-02-18 1990-08-30 Lohmann Therapie Syst Lts Therapeutisches system zur verzoegerten und gesteuerten transdermalen oder transmucosalen verabreichung von wirkstoffen (i)
US5462744A (en) * 1989-12-01 1995-10-31 Boehringer Ingelheim Kg Transdermal system for the administration of pharmacological compounds under pH-controlled conditions
DE3939703C2 (de) * 1989-12-01 1998-07-02 Boehringer Ingelheim Kg Verbesserte transdermale Applikation von pharmakologisch aktiven Verbindungen
US5496471A (en) * 1990-01-08 1996-03-05 Ciba-Geigy Corporation Apparatus for removing components from solutions
US5088978A (en) * 1990-01-26 1992-02-18 Gensia Pharmaceuticals, Inc. Apparatus and method for iontophoretic transfer
CA2120748A1 (en) * 1991-10-16 1993-04-29 Arto Olavi Urtti Peroral drug delivery system
JPH09512006A (ja) * 1994-04-13 1997-12-02 チバ−ガイギー アクチェンゲゼルシャフト 時間的に調節された薬物供給システム
GB2290964A (en) * 1994-07-08 1996-01-17 Arto Olavi Urtti Transdermal drug delivery system
DE4429663C2 (de) * 1994-08-20 1997-09-11 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit Hydrolyseschutz
US6512010B1 (en) * 1996-07-15 2003-01-28 Alza Corporation Formulations for the administration of fluoxetine
US6203817B1 (en) 1997-02-19 2001-03-20 Alza Corporation Reduction of skin reactions caused by transdermal drug delivery
US20030091629A1 (en) * 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
US6974590B2 (en) 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
US20030118645A1 (en) * 1998-04-29 2003-06-26 Pather S. Indiran Pharmaceutical compositions for rectal and vaginal administration
US6699497B1 (en) 1998-07-24 2004-03-02 Alza Corporation Formulations for the transdermal administration of fenoldopam
US6645520B2 (en) * 1999-12-16 2003-11-11 Dermatrends, Inc. Transdermal administration of nonsteroidal anti-inflammatory drugs using hydroxide-releasing agents as permeation enhancers
US6586000B2 (en) * 1999-12-16 2003-07-01 Dermatrends, Inc. Hydroxide-releasing agents as skin permeation enhancers
US20030104041A1 (en) * 1999-12-16 2003-06-05 Tsung-Min Hsu Transdermal and topical administration of drugs using basic permeation enhancers
US20030068356A1 (en) * 2001-07-10 2003-04-10 Pather S. Indiran Sequential drug delivery systems
GB0217056D0 (en) * 2002-07-23 2002-08-28 Ass Octel Use
US20040258742A1 (en) * 2003-04-11 2004-12-23 Van Osdol William Woodson Transdermal administration of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methyl guanidines
AU2004311879B2 (en) * 2003-12-31 2010-08-05 Cima Labs Inc. Effervescent oral opiate dosage form
US7858121B2 (en) 2003-12-31 2010-12-28 Cima Labs, Inc. Effervescent oral fentanyl dosage form and methods of administering fentanyl
KR101184138B1 (ko) * 2003-12-31 2012-09-19 시마 랩스 인크. 일반적인 선형 발포성 경구 펜타닐 투약 제형 및 투여 방법
DE102004009903A1 (de) * 2004-02-26 2005-09-22 Grünenthal GmbH Pflaster mit reduzierter Hautirritation
JP4557596B2 (ja) * 2004-04-28 2010-10-06 積水化成品工業株式会社 外用貼付剤およびその製造方法、並びにその使用方法
WO2006047362A2 (en) 2004-10-21 2006-05-04 Durect Corporation Transdermal delivery systems
US8252319B2 (en) 2004-10-21 2012-08-28 Durect Corporation Transdermal delivery system for sufentanil
US7803148B2 (en) * 2006-06-09 2010-09-28 Neurosystec Corporation Flow-induced delivery from a drug mass
CA2657380A1 (en) * 2006-07-20 2008-01-24 Neurosystec Corporation Devices, systems and methods for ophthalmic drug delivery
US20110104247A1 (en) * 2008-03-25 2011-05-05 Takeshi Ito Composition for stabilizing beta-blocker and transdermally absorbable preparation comprising the same
US20110184229A1 (en) * 2009-05-01 2011-07-28 Allergan, Inc. Laparoscopic gastric band with active agents
JP2015530375A (ja) * 2012-08-15 2015-10-15 ダウ コーニング コーポレーションＤｏｗ Ｃｏｒｎｉｎｇ Ｃｏｒｐｏｒａｔｉｏｎ 多層薬物送達システム
SG11202000415PA (en) * 2017-07-26 2020-02-27 Corium Inc Transdermal delivery system with a microporous membrane having solvent-filled pores

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3797494A (en) * 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
US4060084A (en) * 1976-09-07 1977-11-29 Alza Corporation Method and therapeutic system for providing chemotherapy transdermally
US4303637A (en) * 1980-04-04 1981-12-01 Alza Corporation Medication indicated for ocular hypertension
JPS57116011A (en) * 1981-01-08 1982-07-19 Nitto Electric Ind Co Ltd Pharmaceutical preparation
US4440777A (en) * 1981-07-07 1984-04-03 Merck & Co., Inc. Use of eucalyptol for enhancing skin permeation of bio-affecting agents
US4460368A (en) * 1981-10-29 1984-07-17 Almedco, Inc. Trans-dermal medication system
US4484921A (en) * 1982-02-01 1984-11-27 Alza Corporation Theophylline therapy utilizing osmotic delivery
DE3319469A1 (de) * 1983-05-28 1984-11-29 Akzo Gmbh, 5600 Wuppertal System zur transdermalen applikation von pharmakotherapeutisch wirksamen substanzen
CA1248450A (en) * 1984-04-05 1989-01-10 Kazuo Kigasawa Soft patch
ZA853488B (en) * 1984-05-10 1986-12-30 American Home Prod Transdermal dosage form
US4568343A (en) * 1984-10-09 1986-02-04 Alza Corporation Skin permeation enhancer compositions
US4645502A (en) * 1985-05-03 1987-02-24 Alza Corporation Transdermal delivery of highly ionized fat insoluble drugs

Also Published As

Publication number Publication date
DE3686897D1 (de) 1992-11-12
US4756710A (en) 1988-07-12
EP0197504B1 (de) 1992-10-07
EP0197504A2 (de) 1986-10-15
JPS61275213A (ja) 1986-12-05
EP0197504A3 (en) 1989-07-12
CA1272954A (en) 1990-08-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee