DE3685600D1 - Stabilisierte fluoreszierende seltenerd-indikatoren und physiologisch-reaktive kennsatz-spezies. - Google Patents

Stabilisierte fluoreszierende seltenerd-indikatoren und physiologisch-reaktive kennsatz-spezies.

Info

Publication number
DE3685600D1
DE3685600D1 DE8686301903T DE3685600T DE3685600D1 DE 3685600 D1 DE3685600 D1 DE 3685600D1 DE 8686301903 T DE8686301903 T DE 8686301903T DE 3685600 T DE3685600 T DE 3685600T DE 3685600 D1 DE3685600 D1 DE 3685600D1
Authority
DE
Germany
Prior art keywords
indicators
rare earth
fluorescent rare
reactive label
label species
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686301903T
Other languages
English (en)
Other versions
DE3685600T2 (de
Inventor
James Robert Schaeffer
Tsang Jan Chen
C O Natl Bureau Of Stand Schen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Clinical Diagnostics Inc
Original Assignee
Eastman Kodak Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eastman Kodak Co filed Critical Eastman Kodak Co
Publication of DE3685600D1 publication Critical patent/DE3685600D1/de
Application granted granted Critical
Publication of DE3685600T2 publication Critical patent/DE3685600T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DE8686301903T 1985-03-18 1986-03-17 Stabilisierte fluoreszierende seltenerd-indikatoren und physiologisch-reaktive kennsatz-spezies. Expired - Lifetime DE3685600T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/713,202 US4735907A (en) 1985-03-18 1985-03-18 Stabilized fluorescent rare earth labels and labeled physiologically reactive species

Publications (2)

Publication Number Publication Date
DE3685600D1 true DE3685600D1 (de) 1992-07-16
DE3685600T2 DE3685600T2 (de) 1993-01-21

Family

ID=24865197

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686301903T Expired - Lifetime DE3685600T2 (de) 1985-03-18 1986-03-17 Stabilisierte fluoreszierende seltenerd-indikatoren und physiologisch-reaktive kennsatz-spezies.

Country Status (5)

Country Link
US (2) US4735907A (de)
EP (1) EP0195623B1 (de)
JP (2) JPS61218945A (de)
CA (1) CA1254131A (de)
DE (1) DE3685600T2 (de)

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NO860139L (no) * 1986-01-16 1987-07-17 Havbrukskjemi A S Fremgangsmaate til registrering av opptak hos organismer, mennesker, dyr og planter.
DE3613111A1 (de) * 1986-04-18 1987-10-22 Behringwerke Ag Dispersionspolymere, verfahren zu ihrer herstellung und ihre verwendung
DE3850981T2 (de) * 1987-02-27 1995-03-30 Eastman Kodak Co Wasserunlösliches Teilchen und immunoreaktives Reagens, analytische Elemente und Verfahren zu ihrer Verwendung.
US5166077A (en) * 1987-04-30 1992-11-24 Nitto Denko Corporation Latex for immobilization of physiologically active substances for immuno nephelometry
US5194300A (en) * 1987-07-15 1993-03-16 Cheung Sau W Methods of making fluorescent microspheres
US5106957A (en) * 1987-11-06 1992-04-21 Baxter Diagnostics Inc. Fluorescent poly(arylpyridine) rare earth chelates
EP0336420B1 (de) * 1988-04-08 1994-03-16 Idemitsu Kosan Company Limited Aromatische Polyäther, fluoreszierende Harzzusammensetzungen, die diese enthalten, und Verfahren für ihre Herstellung
US5202423A (en) * 1988-07-08 1993-04-13 Wallac Oy Terpyridine derivatives
EP0511201A1 (de) * 1990-01-17 1992-11-04 Wallac Oy Oligosaccharidderivate gebunden an lanthanid-chelate und an eine reaktive gruppe
GB9003593D0 (en) * 1990-02-16 1990-04-11 Pa Consulting Services Improvements in or relating to fluorescence assays
DE69128109T2 (de) * 1990-07-13 1998-03-19 Canon Kk Nachweisreagens
US5200315A (en) * 1990-07-25 1993-04-06 Eastman Kodak Company Particulate biologically active reagent containing polyoxyalkylene side chains, analytical element and methods for use of the reagent
FI88654C (fi) * 1991-03-15 1993-06-10 Datacity Center Oy Fluorescenshoejningsmetod
FR2689516B1 (fr) * 1992-04-07 2002-03-22 Prolabo Sa Latex fluorescent possédant un seuil de détection en émission fluorescente très faible.
US6132764A (en) * 1994-08-05 2000-10-17 Targesome, Inc. Targeted polymerized liposome diagnostic and treatment agents
US5620850A (en) 1994-09-26 1997-04-15 President And Fellows Of Harvard College Molecular recognition at surfaces derivatized with self-assembled monolayers
US5580749A (en) * 1994-10-21 1996-12-03 Georgia Tech Research Corporation Internal reference for chemically modified spheres
US7014992B1 (en) 1996-11-05 2006-03-21 Clinical Micro Sensors, Inc. Conductive oligomers attached to electrodes and nucleoside analogs
US5981296A (en) * 1997-02-18 1999-11-09 Dade Behring Inc. Stabilization of particle reagents
FR2762394B1 (fr) * 1997-04-16 1999-05-28 Bio Merieux Compose ligand de coordination et utilisation pour fixer un materiel biologique
DE69842134D1 (de) 1997-06-12 2011-03-31 Clinical Micro Sensors Inc Elektronische verfahren und vorrichtung zum nachweis von analyten
US6214628B1 (en) * 1998-01-14 2001-04-10 Joseph R. Lakowicz Method of conducting an assay of a sample containing an analyte of interest
US7087148B1 (en) 1998-06-23 2006-08-08 Clinical Micro Sensors, Inc. Binding acceleration techniques for the detection of analytes
US6184287B1 (en) 1999-01-26 2001-02-06 Omnova Solutions Inc. Polymeric latexes prepared in the presence of 2-acrylamido-2-methylpropanesulfonate
US20020177135A1 (en) * 1999-07-27 2002-11-28 Doung Hau H. Devices and methods for biochip multiplexing
US7312087B2 (en) * 2000-01-11 2007-12-25 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
US6132958A (en) * 1999-05-27 2000-10-17 The Rockefeller University Fluorescent bead for determining the temperature of a cell and methods of use thereof
US6703248B1 (en) * 1999-12-15 2004-03-09 Dade Behring Marburg Gmbh Particles for diagnostic and therapeutic use
US20030082103A1 (en) * 2000-10-11 2003-05-01 Targesome, Inc. Targeted therapeutic lipid constructs having cell surface targets
US20030129223A1 (en) * 2000-10-11 2003-07-10 Targesome, Inc. Targeted multivalent macromolecules
US20030133972A1 (en) * 2000-10-11 2003-07-17 Targesome, Inc. Targeted multivalent macromolecules
EP1412749A4 (de) * 2001-06-28 2006-12-13 Ia Inc Faseroptisches sensorarray
JP4963789B2 (ja) * 2002-12-19 2012-06-27 ナノキャリア株式会社 蛍光体または造影剤を含有するラテックスポリマー粒子およびそれらの製造方法
WO2004056895A1 (ja) * 2002-12-19 2004-07-08 Tokyo University Of Science, Educational Foundation ラテックス粒子およびその製造方法
US7468413B2 (en) * 2004-01-30 2008-12-23 Khodia Inc. Rare earth aggregate formulation using di-block copolmers
WO2007003327A1 (en) * 2005-07-01 2007-01-11 Roche Diagnostics Gmbh Carboxylated latex particles
JP2007146149A (ja) * 2005-11-02 2007-06-14 Fujifilm Corp 蛍光性重合体微粒子、蛍光性重合体微粒子の製造方法、蛍光検出キット及び蛍光検出方法
JP2008074892A (ja) * 2006-09-19 2008-04-03 Fujifilm Corp 蛍光性重合体微粒子セット、蛍光検出用複合体セット、蛍光性重合体微粒子組成物及び蛍光検出方法
US8153442B2 (en) * 2009-10-21 2012-04-10 Siemens Healthcare Diagnostics Inc. Stabilization of signal generation in particles used in assays
WO2012009721A1 (en) 2010-07-16 2012-01-19 Elitech Holding B.V. Orthogonal nucleic acid affinity pairs
JP5465758B2 (ja) * 2011-09-26 2014-04-09 富士フイルム株式会社 蛍光粒子を用いたサイロキシン免疫アッセイ
GB201216121D0 (en) * 2012-09-10 2012-10-24 Novartis Ag Sample quantification by disc centrifugation
US9834808B2 (en) 2016-01-21 2017-12-05 SeLux Diagnostics, Inc. Methods for rapid antibiotic susceptibility testing
CN109072280B (zh) 2016-01-21 2022-10-14 赛录科试诊断公司 用于快速抗微生物剂敏感性测试的方法
EP3559252A1 (de) 2016-12-23 2019-10-30 Selux Diagnostics, Inc. Verfahren für verbesserten schnelltest auf antimikrobielle suszeptibilität

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US4264766A (en) * 1877-09-19 1981-04-28 Hoffmann-La Roche Inc. Immunological diagnostic reagents
US3853987A (en) * 1971-09-01 1974-12-10 W Dreyer Immunological reagent and radioimmuno assay
GB1506017A (en) * 1974-03-04 1978-04-05 Int Diagnostic Tech Fluorometric system and method for the detection of biologically derived substances
US4045384A (en) * 1976-07-23 1977-08-30 The Dow Chemical Company Method for forming an amide bond between a latex and protein
US4283382A (en) * 1977-12-28 1981-08-11 Eastman Kodak Company Fluorescent labels comprising rare earth chelates
US4259313A (en) * 1978-10-18 1981-03-31 Eastman Kodak Company Fluorescent labels
US4258001A (en) * 1978-12-27 1981-03-24 Eastman Kodak Company Element, structure and method for the analysis or transport of liquids
SE428332B (sv) * 1979-03-08 1983-06-20 Wallac Oy Forfarande for fluorescensspektroskopisk bestemning av biologiskt aktivt emne, sasom hapten, antikropp eller antigen
NL8000173A (nl) * 1980-01-11 1981-08-03 Akzo Nv Toepassing van in water dispergeerbare, hydrofobe kleurstoffen als label in immunochemische testen.
EP0054685B1 (de) * 1980-12-23 1986-07-09 Roche Diagnostics GmbH Hydrophile Latexpartikel, Verfahren zu deren Herstellung und deren Verwendung
CA1205028A (en) * 1981-07-01 1986-05-27 Jerald C. Hinshaw Fluorescent chelates and labeled specific binding reagents prepared therefrom
US4401765A (en) * 1981-09-01 1983-08-30 E. I. Du Pont De Nemours And Company Covalently bonded high refractive index particle reagents and their use in light scattering immunoassays
US4434150A (en) * 1981-10-19 1984-02-28 Ortho Diagnostic Systems, Inc. Immunological reagents employing polymeric backbone possessing reactive functional groups
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Also Published As

Publication number Publication date
US4784912A (en) 1988-11-15
EP0195623A2 (de) 1986-09-24
EP0195623A3 (en) 1989-08-09
EP0195623B1 (de) 1992-06-10
CA1254131A (en) 1989-05-16
US4735907A (en) 1988-04-05
JPS62142275A (ja) 1987-06-25
JPS61218945A (ja) 1986-09-29
DE3685600T2 (de) 1993-01-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC., ROCH

8328 Change in the person/name/address of the agent

Free format text: STREHL, SCHUEBEL-HOPF, GROENING & PARTNER, 80538 MUENCHEN