DE3677804D1 - Therapeutische verwendung von zinnmesoporphyrin. - Google Patents

Therapeutische verwendung von zinnmesoporphyrin.

Info

Publication number
DE3677804D1
DE3677804D1 DE8686104120T DE3677804T DE3677804D1 DE 3677804 D1 DE3677804 D1 DE 3677804D1 DE 8686104120 T DE8686104120 T DE 8686104120T DE 3677804 T DE3677804 T DE 3677804T DE 3677804 D1 DE3677804 D1 DE 3677804D1
Authority
DE
Germany
Prior art keywords
mammals
heme
mesoporphyrine
tin
therapeutic use
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686104120T
Other languages
English (en)
Inventor
Attallah Kappas
George S Drummond
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rockefeller University
Original Assignee
Rockefeller University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rockefeller University filed Critical Rockefeller University
Application granted granted Critical
Publication of DE3677804D1 publication Critical patent/DE3677804D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE8686104120T 1985-03-25 1986-03-25 Therapeutische verwendung von zinnmesoporphyrin. Expired - Lifetime DE3677804D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/715,515 US4657902A (en) 1985-03-25 1985-03-25 Therapeutic use of tin mesoporphyrin

Publications (1)

Publication Number Publication Date
DE3677804D1 true DE3677804D1 (de) 1991-04-11

Family

ID=24874343

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686104120T Expired - Lifetime DE3677804D1 (de) 1985-03-25 1986-03-25 Therapeutische verwendung von zinnmesoporphyrin.

Country Status (15)

Country Link
US (1) US4657902A (de)
EP (1) EP0196079B1 (de)
JP (1) JPS62500787A (de)
KR (1) KR870700341A (de)
AT (1) ATE61221T1 (de)
AU (1) AU567041B2 (de)
CA (1) CA1293504C (de)
DE (1) DE3677804D1 (de)
DK (1) DK162716C (de)
ES (1) ES8800670A1 (de)
GR (1) GR860768B (de)
IE (1) IE58532B1 (de)
PH (2) PH23102A (de)
WO (1) WO1986005685A1 (de)
ZA (1) ZA861793B (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657902A (en) * 1985-03-25 1987-04-14 The Rockefeller University Therapeutic use of tin mesoporphyrin
CA1311239C (en) * 1985-10-23 1992-12-08 Isao Sakata Porphyrin derivatives, and their production and use
EP0249966A1 (de) * 1986-06-20 1987-12-23 The Rockefeller University Zinndiioddeuteroporphyrin, seine Herstellung und Verwendung und pharmazeutische Zusammensetzungen davon
US4782049A (en) * 1986-12-08 1988-11-01 The Rockefeller University Tin protoporphyrin and tin mesoporphyrin in the treatment of psoriasis
US4831024A (en) * 1987-10-15 1989-05-16 The Board Of Trustees Of The Leland Stanford Junior University Method to prevent neonatal jaundice
US4997828A (en) * 1989-02-14 1991-03-05 The Rockefeller University Method of weight control by low level administration of cobalt protoporphyrin or cobalt mesoporphyrin
WO1991004029A1 (en) * 1989-09-25 1991-04-04 The Rockefeller University Orally administered porphyrins to control intestinal iron absorption
US5010073A (en) * 1989-10-05 1991-04-23 The Rockefeller University Use of liposomes as carriers for metalloporphyrins
US5192757A (en) * 1990-12-20 1993-03-09 Glaxo Inc. Cobalt porphyrins
US5149697A (en) * 1991-04-18 1992-09-22 Glaxo Inc. Cobalt porphyrin pharmaceutical compositions
FR2676738B1 (fr) * 1991-05-22 1995-05-05 Ir2M Nouveau derive organique de metal de transition a structure porphyrinique, composition therapeutique le contenant, en particulier a activite hypoglycemiante.
US5493017A (en) * 1992-08-14 1996-02-20 The Trustees Of The University Of Pennsylvania Ring-metalated porphyrins
US5817830A (en) * 1992-08-14 1998-10-06 Trustees Of The University Of Pennsylvania Pyrrolic compounds
US5371199B1 (en) * 1992-08-14 1995-12-26 Univ Pennsylvania Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor
US5599924A (en) * 1992-08-14 1997-02-04 Trustees Of The University Of Pennsylvania Electron-deficient porphyrins and processes and intermediates for preparing same
WO1994028906A1 (en) * 1993-06-14 1994-12-22 The Rockefeller University Treatment of neonatal hyperbilirubin with metalloporphyrin
US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
FI100454B (fi) * 1995-01-30 1997-12-15 Leiras Oy Hemi-tuotteiden uusi lääkinnällinen käyttö
AU6497996A (en) * 1995-08-02 1997-02-26 Warner-Lambert Company Amino acid complexes of cobalt (iii) mesoporphyrin ix and cobalt (iii) protoporphyrin ix
EP1045851B1 (de) 1997-11-03 2003-04-23 Duke University Substituierte porphyrinen
CN1093541C (zh) * 1998-01-19 2002-10-30 徐濂 金属卟啉及其生产工艺
ES2163951B1 (es) 1998-07-29 2003-05-16 Airbus Espana Sl Un sistema de proteccion contra descargas electricas, especialmente rayos, de componentes estructurales de aviones.
ES2162718A1 (es) 1998-07-29 2002-01-01 Const Aeronauticas Sa Un sistema de proteccion contra descargas electricas, especialmente rayos, de componentes estructurales de aviones.
EP1117384A1 (de) * 1998-10-01 2001-07-25 Elan Pharma International Limited Nanopartikelformulierungen mit kontrollierter wirkstofffreisetzung
ES2385486T3 (es) * 1999-01-25 2012-07-25 National Jewish Health Porfirinas sustituidas y su uso terapéutico
DE60233317D1 (de) * 2001-01-19 2009-09-24 Nat Jewish Med & Res Center Medikament zum schutz in der radiotherapie
GB0111872D0 (en) * 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
EP1439842A4 (de) * 2001-06-01 2009-09-02 Nat Jewish Med & Res Center Oxidantienfänger zur behandlung von diabetes oder zur verwendung bei der transplantation oder induktion von immuntoleranz
US20080026984A1 (en) * 2002-02-04 2008-01-31 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
AU2003208525B9 (en) * 2002-02-04 2009-08-27 Alfama-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda Amend the invention title to read Method for treating a mammal by administration of a compound having the ability to release CO, compounds having the ability to release CO and pharmaceutical compositions thereof
US7968605B2 (en) * 2002-02-04 2011-06-28 ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
EP2270016A1 (de) 2002-06-04 2011-01-05 InfaCare Pharmaceutical Corporation Herstellung von Metallmesoporphyrinhalegonidverbindungen
US7375216B2 (en) * 2002-06-04 2008-05-20 Infacare Pharmaceutical Corporation Preparation of metal mesoporphyrin compounds
EP1513537A4 (de) * 2002-06-07 2006-09-06 Univ Duke Substituierte porphyrine
GB2395432B (en) * 2002-11-20 2005-09-14 Northwick Park Inst For Medica Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs
US20040097481A1 (en) * 2002-11-20 2004-05-20 Benjamin Levinson Water-soluble mesoporphyrin compounds and methods of preparation
US7008937B2 (en) * 2003-06-10 2006-03-07 Frontier Scientific, Inc. Porphyrins and metalloporphyrins for inhibiting heme iron uptake
EP1865777A4 (de) * 2005-04-01 2008-07-16 Infacare Pharmaceutical Corp Zusammensetzungen und verabreichung von stannsoporfin
US20060222668A1 (en) * 2005-04-01 2006-10-05 Wellspring Pharmaceutical Corporation Stannsoporfin compositions, drug products and methods of manufacture
WO2007073226A1 (en) * 2005-12-20 2007-06-28 Alfama - Investigação E Desenvolvimento De Produtos Farmacêuticos Lda Method for treating a mammal by administration of a compound having the ability to release co
GB0601394D0 (en) 2006-01-24 2006-03-01 Hemocorm Ltd Therapeutic delivery of carbon monoxide
ES2556359T3 (es) * 2006-10-04 2016-01-15 Infacare Pharmaceutical Corporation Procedimiento para la producción a gran escala de estansoporfina de alta pureza
KR101646066B1 (ko) 2008-05-23 2016-08-05 내셔날 쥬이쉬 헬스 알킬화 종으로의 노출과 관련된 상해를 치료하는 방법
EP2691398B1 (de) 2011-03-30 2016-09-28 InfaCare Pharmaceutical Corporation Verfahren zur herstellung von mesoporphyrinen
EP2699242B1 (de) 2011-04-19 2017-11-01 Alfama, Inc. Kohlenmonoxidfreisetzende moleküle und ihre verwendungen
EP2734235B1 (de) 2011-07-21 2017-03-22 Alfama, Inc. Kohlenmonoxidfreisetzende rutheniummoleküle und ihre verwendungen
GB201120860D0 (en) 2011-12-05 2012-01-18 Cambridge Entpr Ltd Cancer immunotherapy
IL287607B (en) 2014-09-29 2022-07-01 Hutchinson Fred Cancer Res Preparations, kits and methods for inducing acquired cellular resistance using induced stress proteins
US10676490B2 (en) 2015-07-07 2020-06-09 Florida Southwestern State College Use of amine carboxyboranes as therapeutic delivery of carbon monoxide and as general drug delivery system in the presence of reactive oxygen species
CN111603472A (zh) * 2020-06-09 2020-09-01 上海市闵行区中心医院 一种锡-中卟啉与青蒿素联合应用在制备抗肿瘤药物中的用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3579533A (en) * 1968-03-18 1971-05-18 Antioch College Preparation of porphin,substituted porphin and metal chelates thereof
US3687863A (en) * 1970-05-25 1972-08-29 Gen Telephone & Elect Optical filters containing tetraphenyl-porphins and method of making same
US4393071A (en) * 1975-03-17 1983-07-12 Naoharu Fujii Method of treating gastric, mammary, lung and uterus tumors
JPS53109929A (en) * 1977-03-04 1978-09-26 Nippon Oil Co Ltd Medicin for malignant tumor
AU555679B2 (en) * 1981-07-15 1986-10-02 Rockefeller University, The Method of decreasing the rate of heme metabolism and composition used therefor
DE3464252D1 (en) * 1983-06-03 1987-07-23 Hoffmann La Roche Labelled molecules for fluorescence immunoassays and processes and intermediates for their preparation
US4657902A (en) * 1985-03-25 1987-04-14 The Rockefeller University Therapeutic use of tin mesoporphyrin

Also Published As

Publication number Publication date
IE58532B1 (en) 1993-10-06
EP0196079B1 (de) 1991-03-06
DK162716C (da) 1992-05-11
CA1293504C (en) 1991-12-24
EP0196079A1 (de) 1986-10-01
AU5549586A (en) 1986-10-23
PH24689A (en) 1990-09-07
ATE61221T1 (de) 1991-03-15
AU567041B2 (en) 1987-11-05
KR870700341A (ko) 1987-12-28
US4657902A (en) 1987-04-14
JPS62500787A (ja) 1987-04-02
ES8800670A1 (es) 1987-11-16
GR860768B (en) 1986-07-22
IE860751L (en) 1986-09-25
DK565786D0 (da) 1986-11-25
PH23102A (en) 1989-04-10
ES553306A0 (es) 1987-11-16
JPH0317806B2 (de) 1991-03-11
ZA861793B (en) 1986-10-29
WO1986005685A1 (en) 1986-10-09
DK162716B (da) 1991-12-02
DK565786A (da) 1986-11-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition