DK565786A - Tin-mesoporphyrin og farmaceutisk praeparat, der indeholder det - Google Patents

Tin-mesoporphyrin og farmaceutisk praeparat, der indeholder det

Info

Publication number
DK565786A
DK565786A DK565786A DK565786A DK565786A DK 565786 A DK565786 A DK 565786A DK 565786 A DK565786 A DK 565786A DK 565786 A DK565786 A DK 565786A DK 565786 A DK565786 A DK 565786A
Authority
DK
Denmark
Prior art keywords
tin
mesoporphyrine
pharmaceutical preparations
preparations containing
mammals
Prior art date
Application number
DK565786A
Other languages
English (en)
Other versions
DK162716C (da
DK565786D0 (da
DK162716B (da
Inventor
Attallah Kappas
George S Drummond
Original Assignee
Univ Rockefeller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rockefeller filed Critical Univ Rockefeller
Publication of DK565786A publication Critical patent/DK565786A/da
Publication of DK565786D0 publication Critical patent/DK565786D0/da
Publication of DK162716B publication Critical patent/DK162716B/da
Application granted granted Critical
Publication of DK162716C publication Critical patent/DK162716C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Epoxy Resins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK565786A 1985-03-25 1986-11-25 Tin-mesoporphyrin og farmaceutisk praeparat, der indeholder det DK162716C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/715,515 US4657902A (en) 1985-03-25 1985-03-25 Therapeutic use of tin mesoporphyrin
US71551585 1985-03-25
PCT/US1986/000445 WO1986005685A1 (en) 1985-03-25 1986-02-28 Therapeutic use of tin mesoporphyrin
US8600445 1986-02-28

Publications (4)

Publication Number Publication Date
DK565786A true DK565786A (da) 1986-11-25
DK565786D0 DK565786D0 (da) 1986-11-25
DK162716B DK162716B (da) 1991-12-02
DK162716C DK162716C (da) 1992-05-11

Family

ID=24874343

Family Applications (1)

Application Number Title Priority Date Filing Date
DK565786A DK162716C (da) 1985-03-25 1986-11-25 Tin-mesoporphyrin og farmaceutisk praeparat, der indeholder det

Country Status (15)

Country Link
US (1) US4657902A (da)
EP (1) EP0196079B1 (da)
JP (1) JPS62500787A (da)
KR (1) KR870700341A (da)
AT (1) ATE61221T1 (da)
AU (1) AU567041B2 (da)
CA (1) CA1293504C (da)
DE (1) DE3677804D1 (da)
DK (1) DK162716C (da)
ES (1) ES8800670A1 (da)
GR (1) GR860768B (da)
IE (1) IE58532B1 (da)
PH (2) PH23102A (da)
WO (1) WO1986005685A1 (da)
ZA (1) ZA861793B (da)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657902A (en) * 1985-03-25 1987-04-14 The Rockefeller University Therapeutic use of tin mesoporphyrin
DE3687399T2 (de) * 1985-10-23 1993-04-29 Nihon Mediphysics Co Ltd Porphyrinderivate, ihre herstellung und verwendung.
EP0249966A1 (en) * 1986-06-20 1987-12-23 The Rockefeller University Tin diiododeuteroporphyrin, its preparation and use, and pharmaceutical compositions thereof
US4782049A (en) * 1986-12-08 1988-11-01 The Rockefeller University Tin protoporphyrin and tin mesoporphyrin in the treatment of psoriasis
US4831024A (en) * 1987-10-15 1989-05-16 The Board Of Trustees Of The Leland Stanford Junior University Method to prevent neonatal jaundice
US4997828A (en) * 1989-02-14 1991-03-05 The Rockefeller University Method of weight control by low level administration of cobalt protoporphyrin or cobalt mesoporphyrin
CA2042398C (en) * 1989-09-25 1995-10-31 George S. Drummond Orally administered porphyrins to control intestinal iron absorption
US5010073A (en) * 1989-10-05 1991-04-23 The Rockefeller University Use of liposomes as carriers for metalloporphyrins
US5192757A (en) * 1990-12-20 1993-03-09 Glaxo Inc. Cobalt porphyrins
US5149697A (en) * 1991-04-18 1992-09-22 Glaxo Inc. Cobalt porphyrin pharmaceutical compositions
FR2676738B1 (fr) * 1991-05-22 1995-05-05 Ir2M Nouveau derive organique de metal de transition a structure porphyrinique, composition therapeutique le contenant, en particulier a activite hypoglycemiante.
US5599924A (en) * 1992-08-14 1997-02-04 Trustees Of The University Of Pennsylvania Electron-deficient porphyrins and processes and intermediates for preparing same
US5371199B1 (en) * 1992-08-14 1995-12-26 Univ Pennsylvania Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor
US5493017A (en) * 1992-08-14 1996-02-20 The Trustees Of The University Of Pennsylvania Ring-metalated porphyrins
US5817830A (en) * 1992-08-14 1998-10-06 Trustees Of The University Of Pennsylvania Pyrrolic compounds
AU7103594A (en) * 1993-06-14 1995-01-03 Rockefeller University, The Treatment of neonatal hyperbilirubin with metalloporphyrin
US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
FI100454B (fi) * 1995-01-30 1997-12-15 Leiras Oy Hemi-tuotteiden uusi lääkinnällinen käyttö
US5929064A (en) * 1995-08-02 1999-07-27 Warner-Lambert Company Amino acid complexes of cobalt (III) mesoporphyrin IX and cobalt (III) protoporphyrin IX
JP2001521939A (ja) 1997-11-03 2001-11-13 デューク・ユニバーシティー 置換されたポルフィリン類
CN1093541C (zh) * 1998-01-19 2002-10-30 徐濂 金属卟啉及其生产工艺
ES2162718A1 (es) 1998-07-29 2002-01-01 Const Aeronauticas Sa Un sistema de proteccion contra descargas electricas, especialmente rayos, de componentes estructurales de aviones.
ES2163951B1 (es) 1998-07-29 2003-05-16 Airbus Espana Sl Un sistema de proteccion contra descargas electricas, especialmente rayos, de componentes estructurales de aviones.
AU6283299A (en) * 1998-10-01 2000-04-17 Elan Pharma International Limited Controlled release nanoparticulate compositions
EP1155019B1 (en) 1999-01-25 2005-12-07 National Jewish Medical and Research Center Substituted porphyrins and their therapeutic use
JP2004520380A (ja) * 2001-01-19 2004-07-08 ナショナル・ジュウィッシュ・メディカル・アンド・リサーチ・センター 癌治療本出願は、2001年1月19日に出願の仮出願番号第60/262,390号の優先権を主張し、その全ての内容は、参照により本願明細書に援用したものとする。
GB0111872D0 (en) * 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
JP2005508864A (ja) * 2001-06-01 2005-04-07 ナショナル・ジュウィッシュ・メディカル・アンド・リサーチ・センター 糖尿病の治療、または移植術における使用、または免疫寛容の誘導のためのオキシダントスカベンジャー
US20080026984A1 (en) * 2002-02-04 2008-01-31 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
EP2042181A1 (en) * 2002-02-04 2009-04-01 ALFAMA-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda. Use of co-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases
US7968605B2 (en) * 2002-02-04 2011-06-28 ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
US7375216B2 (en) * 2002-06-04 2008-05-20 Infacare Pharmaceutical Corporation Preparation of metal mesoporphyrin compounds
US6818763B2 (en) 2002-06-04 2004-11-16 Wellspring Pharmaceutical Corporation Preparation of metal mesoporphyrin halide compounds
EP1513537A4 (en) * 2002-06-07 2006-09-06 Univ Duke Substituted porphyrins
US20040097481A1 (en) * 2002-11-20 2004-05-20 Benjamin Levinson Water-soluble mesoporphyrin compounds and methods of preparation
GB2395432B (en) * 2002-11-20 2005-09-14 Northwick Park Inst For Medica Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs
US7008937B2 (en) * 2003-06-10 2006-03-07 Frontier Scientific, Inc. Porphyrins and metalloporphyrins for inhibiting heme iron uptake
EP1865777A4 (en) * 2005-04-01 2008-07-16 Infacare Pharmaceutical Corp STANNSOPORFIN COMPOSITIONS AND ADMINISTRATION
US20060222668A1 (en) * 2005-04-01 2006-10-05 Wellspring Pharmaceutical Corporation Stannsoporfin compositions, drug products and methods of manufacture
WO2007073226A1 (en) * 2005-12-20 2007-06-28 Alfama - Investigação E Desenvolvimento De Produtos Farmacêuticos Lda Method for treating a mammal by administration of a compound having the ability to release co
GB0601394D0 (en) 2006-01-24 2006-03-01 Hemocorm Ltd Therapeutic delivery of carbon monoxide
JP5524622B2 (ja) 2006-10-04 2014-06-18 インファケア ファーマスーティカル,コーポレイション スタンソポルフィンの高純度で大規模な製造
US11382895B2 (en) 2008-05-23 2022-07-12 National Jewish Health Methods for treating injury associated with exposure to an alkylating species
ES2609110T3 (es) 2011-03-30 2017-04-18 Infacare Pharmaceutical Corporation Procedimientos de síntesis de mesoporfirinas metálicas
US9163044B2 (en) 2011-04-19 2015-10-20 Alfama, Inc. Carbon monoxide releasing molecules and uses thereof
WO2013013179A1 (en) 2011-07-21 2013-01-24 Alfama, Inc. Ruthenium carbon monoxide releasing molecules and uses thereof
GB201120860D0 (en) 2011-12-05 2012-01-18 Cambridge Entpr Ltd Cancer immunotherapy
CN107072190B (zh) 2014-09-29 2020-10-09 弗莱德哈钦森癌症研究中心 使用应激蛋白质诱导剂诱导获得性细胞抗性的组合物、试剂盒及方法
WO2017007955A1 (en) 2015-07-07 2017-01-12 The Research Foundation For The State University Of New York Use of amine carboxyboranes as therapeutic delivery of carbon monoxide and as general drug delivery system in the presence of reactive oxygen species
CN111603472A (zh) * 2020-06-09 2020-09-01 上海市闵行区中心医院 一种锡-中卟啉与青蒿素联合应用在制备抗肿瘤药物中的用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3579533A (en) * 1968-03-18 1971-05-18 Antioch College Preparation of porphin,substituted porphin and metal chelates thereof
US3687863A (en) * 1970-05-25 1972-08-29 Gen Telephone & Elect Optical filters containing tetraphenyl-porphins and method of making same
US4393071A (en) * 1975-03-17 1983-07-12 Naoharu Fujii Method of treating gastric, mammary, lung and uterus tumors
JPS53109929A (en) * 1977-03-04 1978-09-26 Nippon Oil Co Ltd Medicin for malignant tumor
CA1176978A (en) * 1981-07-15 1984-10-30 Attallah Kappas Method of controlling of heme metabolism
EP0127797B1 (de) * 1983-06-03 1987-06-16 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Markermoleküle für Fluoreszenz-Immuno-Assays sowie Verfahren und Zwischenprodukte zu deren Herstellung
US4657902A (en) * 1985-03-25 1987-04-14 The Rockefeller University Therapeutic use of tin mesoporphyrin

Also Published As

Publication number Publication date
DE3677804D1 (de) 1991-04-11
JPH0317806B2 (da) 1991-03-11
ES8800670A1 (es) 1987-11-16
WO1986005685A1 (en) 1986-10-09
CA1293504C (en) 1991-12-24
IE58532B1 (en) 1993-10-06
ATE61221T1 (de) 1991-03-15
EP0196079B1 (en) 1991-03-06
DK162716C (da) 1992-05-11
GR860768B (en) 1986-07-22
ES553306A0 (es) 1987-11-16
US4657902A (en) 1987-04-14
PH23102A (en) 1989-04-10
ZA861793B (en) 1986-10-29
JPS62500787A (ja) 1987-04-02
EP0196079A1 (en) 1986-10-01
DK565786D0 (da) 1986-11-25
AU567041B2 (en) 1987-11-05
KR870700341A (ko) 1987-12-28
PH24689A (en) 1990-09-07
DK162716B (da) 1991-12-02
IE860751L (en) 1986-09-25
AU5549586A (en) 1986-10-23

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