DE3677554D1 - Durchfluss-zytometriegeraet mit verbesserter lichtstrahljustierung. - Google Patents

Durchfluss-zytometriegeraet mit verbesserter lichtstrahljustierung.

Info

Publication number
DE3677554D1
DE3677554D1 DE8686105339T DE3677554T DE3677554D1 DE 3677554 D1 DE3677554 D1 DE 3677554D1 DE 8686105339 T DE8686105339 T DE 8686105339T DE 3677554 T DE3677554 T DE 3677554T DE 3677554 D1 DE3677554 D1 DE 3677554D1
Authority
DE
Germany
Prior art keywords
light beam
flow cytometer
improved light
beam adjustment
adjustment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686105339T
Other languages
German (de)
English (en)
Inventor
North, Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of DE3677554D1 publication Critical patent/DE3677554D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1452—Adjustment of focus; Alignment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DE8686105339T 1985-07-29 1986-04-17 Durchfluss-zytometriegeraet mit verbesserter lichtstrahljustierung. Expired - Lifetime DE3677554D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/760,205 US4989977A (en) 1985-07-29 1985-07-29 Flow cytometry apparatus with improved light beam adjustment

Publications (1)

Publication Number Publication Date
DE3677554D1 true DE3677554D1 (de) 1991-03-28

Family

ID=25058424

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686105339T Expired - Lifetime DE3677554D1 (de) 1985-07-29 1986-04-17 Durchfluss-zytometriegeraet mit verbesserter lichtstrahljustierung.

Country Status (5)

Country Link
US (1) US4989977A (enExample)
EP (1) EP0210343B1 (enExample)
JP (1) JPS62124441A (enExample)
DE (1) DE3677554D1 (enExample)
MY (1) MY102913A (enExample)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63307332A (ja) * 1987-06-08 1988-12-15 Hitachi Ltd 光計測式生体細胞分析装置
US5224058A (en) * 1990-05-01 1993-06-29 Becton, Dickinson And Company Method for data transformation
IL101522A (en) * 1992-04-08 1997-09-30 Combact Imaging Systems Ltd Detection of microorganisms in a sample and determination of the sensitivity of microorganisms to antibiotics
JPH05340865A (ja) * 1992-06-09 1993-12-24 Canon Inc 測定装置
US5656499A (en) * 1994-08-01 1997-08-12 Abbott Laboratories Method for performing automated hematology and cytometry analysis
DE69532045T2 (de) * 1994-08-01 2004-07-08 Abbott Laboratories, Abbott Park Verfahren und Vorrichtung zur Vorbereitung einer Flüssigkeit
US5812419A (en) * 1994-08-01 1998-09-22 Abbott Laboratories Fully automated analysis method with optical system for blood cell analyzer
US5631165A (en) * 1994-08-01 1997-05-20 Abbott Laboratories Method for performing automated hematology and cytometry analysis
US5891734A (en) * 1994-08-01 1999-04-06 Abbott Laboratories Method for performing automated analysis
US5831730A (en) * 1996-12-06 1998-11-03 United Sciences, Inc. Method for monitoring particulates using beam-steered solid-state light source
ATE298084T1 (de) 1997-01-31 2005-07-15 Horticulture & Food Res Inst Optische vorrichtung und methode
DE19723999B4 (de) * 1997-06-06 2008-04-10 Schwartz, Margit Vorrichtung zur Messung von Partikelabmessungen in Fluiden
DE19755589C2 (de) * 1997-12-15 2002-11-07 Fraunhofer Ges Forschung Vorrichtung für dreidimensionale Kreuzkorrelationstechnik und Verfahren zur Durchführung der Justage von Detektionsoptiken zur Messung von Kreuzkorrelationsfunktionen in flüssigen Medien
US6071689A (en) * 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US6149867A (en) * 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US7498164B2 (en) 1998-05-16 2009-03-03 Applied Biosystems, Llc Instrument for monitoring nucleic acid sequence amplification reaction
US6818437B1 (en) 1998-05-16 2004-11-16 Applera Corporation Instrument for monitoring polymerase chain reaction of DNA
EP1078245B1 (en) 1998-05-16 2008-08-06 Applera Corporation Instrument for monitoring polymerase chain reaction of dna
US7208265B1 (en) * 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
WO2001040764A2 (en) * 1999-12-01 2001-06-07 Dubelaar Research Instruments Engineering Apparatus for the detection of particles
US6809804B1 (en) 2000-05-11 2004-10-26 Becton, Dickinson And Company System and method for providing improved event reading and data processing capabilities in a flow cytometer
US20040031071A1 (en) * 2000-10-05 2004-02-12 Xy, Inc. System of hysteroscopic insemination of mares
CA2468774C (en) 2000-11-29 2015-06-30 George E. Seidel System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US7280207B2 (en) * 2001-07-25 2007-10-09 Applera Corporation Time-delay integration in a flow cytometry system
DK1636561T3 (da) 2002-07-15 2011-05-16 Univ Texas Kombinatorisk proteinbiblioteksscreening ved hjælp af periplasmatisk ekspression
EP1542529A4 (en) * 2002-07-22 2006-08-09 Xy Inc SYSTEM FOR TREATING SPERMATIC CELL
BRPI0313163B1 (pt) * 2002-08-01 2015-11-17 Univ Colorado State sistema de separação de células espermáticas a baixa pressão
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
AU2003265471B2 (en) * 2002-08-15 2009-08-06 Xy, Llc. High resolution flow cytometer
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
JP2004109010A (ja) * 2002-09-19 2004-04-08 Otsuka Denshi Co Ltd 散乱光測定装置
DK2305172T3 (en) 2003-03-28 2016-08-22 Inguran Llc DEVICE AND PROCEDURES TO PROVIDE SEXUAL ANIMAL SEED
NZ544103A (en) * 2003-05-15 2010-10-29 Xy Llc Efficient haploid cell sorting for flow cytometer systems
PL2151243T3 (pl) 2004-03-29 2013-03-29 Inguran Llc Zawiesiny plemników do sortowania na populacje wzbogacone w niosące chromosom X lub Y
MX2007000888A (es) 2004-07-22 2007-04-02 Monsanto Technology Llc Procedimiento para enriquecer una poblacion de celulas de esperma.
US7110192B2 (en) * 2005-01-12 2006-09-19 Dako Denmark A/S System and method for a composite lens for a flow cytometer
ATE555128T1 (de) 2006-11-30 2012-05-15 Res Dev Foundation Verbesserte immunglobulin-bibliotheken
US8629245B2 (en) 2007-05-01 2014-01-14 Research Development Foundation Immunoglobulin Fc libraries
WO2009006422A1 (en) * 2007-06-29 2009-01-08 Stem Cell Products, Inc. Automated method and apparatus for embryonic stem cell culture
US7787197B2 (en) 2007-09-14 2010-08-31 Becton, Dickinson And Company Beam-adjusting optics
US9587270B2 (en) 2009-06-29 2017-03-07 Luminex Corporation Chimeric primers with hairpin conformations and methods of using same
US8223445B2 (en) * 2009-09-21 2012-07-17 Cytopeia Lens positioning apparatus
US8589851B2 (en) * 2009-12-15 2013-11-19 Memoir Systems, Inc. Intelligent memory system compiler
CA2826467C (en) 2011-02-07 2019-11-12 Research Development Foundation Engineered immunoglobulin fc polypeptides
US9241983B2 (en) 2011-04-29 2016-01-26 Baylor College Of Medicine Ureaplasma vaccine and antibody for prevention and treatment of human, animal and cell culture infection
HK1201568A1 (en) 2011-09-29 2015-09-04 露美内克丝公司 Hydrolysis probes
EP2809783A2 (en) 2012-02-02 2014-12-10 Invenra, Inc. High throughput screen for biologically active polypeptides
EP3521452B1 (en) 2013-06-19 2021-08-04 Luminex Corporation Real-time multiplexed hydrolysis probe assay
CN105555971B (zh) 2013-08-09 2017-08-29 卢米耐克斯公司 用于在核酸测定中改善熔链分辨和多重性的探针
EP3967771B1 (en) 2014-08-11 2023-10-04 Luminex Corporation Probes for improved melt discrimination and multiplexing in nucleic acid assays
US10900059B2 (en) 2014-10-14 2021-01-26 Research Development Foundation Methods for generating engineered enzymes
AU2016219511B2 (en) 2015-02-09 2020-11-12 Research Development Foundation Engineered immunoglobulin Fc polypeptides displaying improved complement activation
WO2017040380A2 (en) 2015-08-28 2017-03-09 Research Development Foundation Engineered antibody fc variants
CN106383081B (zh) * 2016-08-22 2019-05-31 清华大学 基于二元光学器件的微流体芯片自动对准方法和系统
WO2019191419A2 (en) * 2018-03-30 2019-10-03 Idexx Laboratories, Inc. Flow cytometer, laser optics assembly thereof, and methods of assembling the same
US11376320B2 (en) 2020-03-05 2022-07-05 Iowa State University Research Foundation, Inc. Immunogenic and vaccine compositions against SARS-CoV-2
CA3258884A1 (en) 2022-06-10 2023-12-14 Research Development Foundation Modified FCRIIB Selective FC IGG1 Variants and Their Uses
US20240264068A1 (en) * 2023-02-07 2024-08-08 OpenAeros LLC Lasers for condensation particle counters

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3705771A (en) * 1970-01-14 1972-12-12 Bio Physics Systems Inc Photoanalysis apparatus
JPS5213423B2 (enExample) * 1971-10-15 1977-04-14
US3826364A (en) * 1972-05-22 1974-07-30 Univ Leland Stanford Junior Particle sorting method and apparatus
US3858851A (en) * 1973-07-05 1975-01-07 Prototron Ass Apparatus for providing a statistical count of particulate material in a fluid
US3941477A (en) * 1974-10-17 1976-03-02 Deutsche Forschungs-Und Versuchsanstalt Fur Luft-Und Raumfahrt E.V. Measuring device for the measurement of fluid flow rates
DE2732272C2 (de) * 1977-07-16 1979-07-05 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts, 6900 Heidelberg Verfahren und Vorrichtung zur Fluoreszenzanalyse von gefärbten Partikeln, insbesondere biologischen Zellen
US4577964A (en) * 1978-09-06 1986-03-25 Ortho Diagnostics, Inc. Apparatus and method for detecting platelets in whole blood
US4293221A (en) * 1979-04-17 1981-10-06 Research Corporation Multidimensional slit-scan flow system
US4350892A (en) * 1980-07-31 1982-09-21 Research Corporation X'-, Y'-, Z'- axis multidimensional slit-scan flow system
US4498766A (en) * 1982-03-25 1985-02-12 Becton, Dickinson And Company Light beam focal spot elongation in flow cytometry devices
JPS5979834A (ja) * 1982-10-29 1984-05-09 Japan Spectroscopic Co 微小粒子分離装置
JPS5979835A (ja) * 1982-10-29 1984-05-09 Japan Spectroscopic Co 微小粒子分析装置
JPS59184841A (ja) * 1983-04-05 1984-10-20 ベクトン・デイツキンソン・アンド・カンパニ− サンプル中の白血球のサブクラスを識別する方法および装置
DD232552A1 (de) * 1983-08-04 1986-01-29 Adw Ddr Verfahren und einrichtung zur zaehlung und klassifizierung von dispergierten teilchen
US4660971A (en) * 1984-05-03 1987-04-28 Becton, Dickinson And Company Optical features of flow cytometry apparatus

Also Published As

Publication number Publication date
US4989977A (en) 1991-02-05
EP0210343B1 (en) 1991-02-20
EP0210343A1 (en) 1987-02-04
MY102913A (en) 1993-03-31
JPS62124441A (ja) 1987-06-05
JPH0544622B2 (enExample) 1993-07-06

Similar Documents

Publication Publication Date Title
DE3677554D1 (de) Durchfluss-zytometriegeraet mit verbesserter lichtstrahljustierung.
DE3677521D1 (de) Optisches ablenkelement.
DE3674223D1 (de) Optisches zeitbereichsreflektometer mit heterodyn-empfang.
DE3671244D1 (de) Fusionspolypeptid mit antigener wirkung.
DE3681052D1 (de) Halbleiterlaser mit verteilter rueckkopplung.
DE3689454D1 (de) Lichtabtastvorrichtung.
DE3683741D1 (de) Kuehlkanal mit faecherfoermigem ausgang.
FR2539685B1 (fr) Luminaire a faisceau orientable
DE3667197D1 (de) Laterne mit fluessigem brennstoff.
NL194596B (nl) Lichtbroneenheid.
DE3681040D1 (de) Endoskop mit lichtleitern.
NL190425C (nl) Verlichtingsarmatuur met asymmetrische lichtbundel.
FI862380A7 (fi) Lasersädettä kestävä materiaali.
DE3679460D1 (de) Optischer aufnahmekopf mit astigmatischer fokussierung.
DE3864268D1 (de) Turbine mit regelbarem durchfluss.
DE58904899D1 (de) Klopfer mit selbststeuerung.
DE68919208D1 (de) Lichtablenkendes element.
BE894489A (fr) Balises lumineuses
DE3688853D1 (de) Tripropylamin-dotierter laser.
DE3679721D1 (de) Winkelgeschwindigkeitsmesser mit vibrierendem ringlaser.
DE3670537D1 (de) Lichtfeder.
DE3574504D1 (de) Lichtabstrahler.
DE3584547D1 (de) Durchflusszytometrie.
DE3686395D1 (de) Logisches optisches bauelement.
DE3587285D1 (de) Optischer empfaenger mit negativer rueckkopplung.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition