DE3672846D1 - Bicycloalkyl-, tricycloalkyl-, azabicycloalkyl- und azatricycloalkyl-amide. - Google Patents

Bicycloalkyl-, tricycloalkyl-, azabicycloalkyl- und azatricycloalkyl-amide.

Info

Publication number
DE3672846D1
DE3672846D1 DE8686101299T DE3672846T DE3672846D1 DE 3672846 D1 DE3672846 D1 DE 3672846D1 DE 8686101299 T DE8686101299 T DE 8686101299T DE 3672846 T DE3672846 T DE 3672846T DE 3672846 D1 DE3672846 D1 DE 3672846D1
Authority
DE
Germany
Prior art keywords
azatricycloalkyl
azabicycloalkyl
tricycloalkyl
bicycloalkyl
amides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686101299T
Other languages
English (en)
Inventor
Richard August Mueller
Richard Allen Partis
James Ronald Deason
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Application granted granted Critical
Publication of DE3672846D1 publication Critical patent/DE3672846D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8686101299T 1985-02-04 1986-01-31 Bicycloalkyl-, tricycloalkyl-, azabicycloalkyl- und azatricycloalkyl-amide. Expired - Fee Related DE3672846D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69805085A 1985-02-04 1985-02-04
US80995485A 1985-12-20 1985-12-20

Publications (1)

Publication Number Publication Date
DE3672846D1 true DE3672846D1 (de) 1990-08-30

Family

ID=27106143

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686101299T Expired - Fee Related DE3672846D1 (de) 1985-02-04 1986-01-31 Bicycloalkyl-, tricycloalkyl-, azabicycloalkyl- und azatricycloalkyl-amide.

Country Status (4)

Country Link
EP (1) EP0190684B1 (de)
JP (1) JPH0662549B2 (de)
CA (1) CA1332057C (de)
DE (1) DE3672846D1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755524A (en) * 1986-01-31 1988-07-05 G. D. Searle & Co. Novel phenolic thioethers as inhibitors of 5-lipoxygenase
US5002967A (en) * 1987-06-05 1991-03-26 G. D. Searle & Co. Phenolic thioethers, sulfoxides, and disulfides as inhibitors of 5-lipoxygenase
US4835189A (en) * 1987-06-05 1989-05-30 G. D. Searle & Co. Phenolic thioalkylamides as inhibitors of 5-lipoxygenase
JPS63310821A (ja) * 1987-06-05 1988-12-19 ジー．ディー．サール　アンド　カンパニー ５−リポキシゲナーゼの阻害剤としてのフエノール性チオエーテル、スルホキサイドおよびジスルフアイド
CH686285A5 (fr) * 1992-08-06 1996-02-29 Beiersdorf Ag Preparation cosmetique ou pharmaceutique servant a retarder le vieillissement de la peau humaine.
US5635514A (en) * 1994-10-25 1997-06-03 G. D. Searle & Company Heteroaralkyl and heteroarylthioalkyl thiophenolic compounds as 5-lipoxgenase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH519012A (de) * 1968-07-26 1972-02-15 Ciba Geigy Ag Farbstoffpräparate
US4029812A (en) * 1976-02-18 1977-06-14 The Dow Chemical Company Novel hypolipidemic 2-(3,5-di-tert-butyl-4-hydroxyphenyl)thio carboxamides
JPS6039262B2 (ja) * 1977-05-11 1985-09-05 ウェルファイド株式会社 第３級ブチルフェノ−ル誘導体

Also Published As

Publication number Publication date
CA1332057C (en) 1994-09-20
EP0190684B1 (de) 1990-07-25
AU589942B2 (en) 1989-10-26
JPS61191670A (ja) 1986-08-26
AU5288386A (en) 1986-08-07
EP0190684A3 (en) 1988-01-07
EP0190684A2 (de) 1986-08-13
JPH0662549B2 (ja) 1994-08-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee