DE3590496T1 - - Google Patents

Info

Publication number
DE3590496T1
DE3590496T1 DE19853590496 DE3590496T DE3590496T1 DE 3590496 T1 DE3590496 T1 DE 3590496T1 DE 19853590496 DE19853590496 DE 19853590496 DE 3590496 T DE3590496 T DE 3590496T DE 3590496 T1 DE3590496 T1 DE 3590496T1
Authority
DE
Germany
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19853590496
Other languages
German (de)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amersham Health Salutar Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of DE3590496T1 publication Critical patent/DE3590496T1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Epidemiology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
DE19853590496 1984-10-04 1985-10-02 Withdrawn DE3590496T1 (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/657,676 US4687658A (en) 1984-10-04 1984-10-04 Metal chelates of diethylenetriaminepentaacetic acid partial esters for NMR imaging

Publications (1)

Publication Number Publication Date
DE3590496T1 true DE3590496T1 (enExample) 1987-02-19

Family

ID=24638194

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19853590496 Withdrawn DE3590496T1 (enExample) 1984-10-04 1985-10-02

Country Status (6)

Country Link
US (1) US4687658A (enExample)
EP (1) EP0200750B1 (enExample)
JP (1) JPS62501288A (enExample)
DE (1) DE3590496T1 (enExample)
GB (1) GB2177086B (enExample)
WO (1) WO1986002005A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3401052A1 (de) * 1983-01-21 1984-07-26 Schering AG, 1000 Berlin und 4709 Bergkamen Diagnostische mittel
DE3710730A1 (de) * 1987-03-31 1988-10-20 Schering Ag Substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3324235A1 (de) * 1983-07-01 1985-01-10 Schering AG, 1000 Berlin und 4709 Bergkamen Neue komplexbildner, komplexe und komplexsalze
US4859451A (en) * 1984-10-04 1989-08-22 Salutar, Inc. Paramagnetic contrast agents for MR imaging
PT81498B (pt) * 1984-11-23 1987-12-30 Schering Ag Processo para a preparacao de composicoes para diagnostico contendo particulas magneticas
US5746999A (en) * 1984-11-23 1998-05-05 Schering Aktiengesellschaft Magnetic particles for diagnostic purposes
DE3614142C2 (de) * 1985-04-26 1996-03-28 Toshiba Kawasaki Kk Verwendung eines Materials für die Diagnose durch Kernresonanz-Spektroskopie
US4899755A (en) * 1985-05-08 1990-02-13 The General Hospital Corporation Hepatobiliary NMR contrast agents
US5422096A (en) * 1985-05-08 1995-06-06 The General Hospital Corporation Hydroxy-aryl metal chelates for diagnostic NMR imaging
US5250285A (en) * 1985-05-08 1993-10-05 The General Hospital Corporation Hydroxy-aryl metal chelates for diagnostic NMR imaging
IT1213029B (it) * 1986-01-30 1989-12-07 Bracco Ind Chimica Spa Chelati di ioni metallici paramagnetici.
GB8700431D0 (en) * 1987-01-09 1987-02-11 Amersham Int Plc Contrast agents
US4863716A (en) * 1987-05-08 1989-09-05 Salutar, Inc. Determination of fallopian tubal patency by magnetic resonance imaging
ATE98631T1 (de) * 1988-01-20 1994-01-15 Ciba Geigy Ag Verfahren zur herstellung von komplexverbindungen.
GB8801646D0 (en) * 1988-01-26 1988-02-24 Nycomed As Chemical compounds
JPH076765B2 (ja) * 1988-06-23 1995-01-30 株式会社日立メディコ 非破壊断面形状検査装置
US5137711A (en) * 1988-07-19 1992-08-11 Mallickrodt Medical, Inc. Paramagnetic dtpa and edta alkoxyalkylamide complexes as mri agents
US5145661A (en) * 1988-08-31 1992-09-08 Wayne State University Method and contrast agent for use in magnetic resonance imaging of abscess
US5045304A (en) * 1988-08-31 1991-09-03 Wayne State University Contras agent having an imaging agent coupled to viable granulocytes for use in magnetic resonance imaging of abscess and a method of preparing and using same
US5702683A (en) * 1989-01-24 1997-12-30 The United States Of America As Represented By The United States Department Of Energy Nuclear magnetic resonance contrast agents
US5011925A (en) * 1989-03-09 1991-04-30 Mallinckrodt, Inc. Morpholinoamido EDTA derivatives
US5384108A (en) * 1989-04-24 1995-01-24 Mallinckrodt Medical, Inc. Magnetic resonance imaging agents
GB2233456A (en) * 1989-06-21 1991-01-09 Gen Electric Co Plc Material detection.
ATE173336T1 (de) * 1989-08-28 1998-11-15 Gen Hospital Corp Hydroxy-aryl metallchelate für bildformung zur nmr diagnose
EP0421697A3 (en) * 1989-09-29 1991-04-17 Smithkline Beecham Corporation Contrast agents and methods for enhancing magnetic resonance imaging
US5494655A (en) * 1990-03-09 1996-02-27 The Regents Of The University Of California Methods for detecting blood perfusion variations by magnetic resonance imaging
US5190744A (en) * 1990-03-09 1993-03-02 Salutar Methods for detecting blood perfusion variations by magnetic resonance imaging
US6994841B1 (en) * 1990-03-09 2006-02-07 Kucharczyk And Moseley Partners Relating to magnetic resonance imaging
US5154914A (en) * 1990-03-12 1992-10-13 Research Corporation Technologies, Inc. Methods of diagnostic image analysis using lipophilic contrast agents
US5242681A (en) * 1990-03-12 1993-09-07 Research Corporation Technologies, Inc. Lipophilic contrast agents for diagnostic image analysis
GB9006606D0 (en) * 1990-03-23 1990-05-23 Allied Colloids Ltd Chelate compositions and their production
GB9007408D0 (en) * 1990-04-02 1990-05-30 Nycomed As Compositions
US5077037A (en) * 1990-08-03 1991-12-31 Mallinckrodt Medical, Inc. Novel compositions for magnetic resonance imaging
US5162109A (en) * 1990-09-13 1992-11-10 Mallinckrodt Medical, Inc. Magnetic resonance imaging agents
GB9024528D0 (en) * 1990-11-12 1991-01-02 Instrumentarium Corp Improvements in and relating to magnetic resonance imaging
US5141740A (en) * 1990-11-21 1992-08-25 Mallinckrodt Medical, Inc. Complexes and compositions for magnetic resonance imaging and usage methods
US5217706A (en) * 1990-11-21 1993-06-08 Mallinckrodt Medical, Inc. Complexes and compositions for magnetic resonance imaging
US5463030A (en) * 1991-05-03 1995-10-31 Research Foundation Of The State Of New York Metal chelating agents for medical application
AU660033B2 (en) * 1991-05-23 1995-06-08 Imarx Pharmaceutical Corp. Liposoluble compounds for magnetic resonance imaging
US5562894A (en) * 1991-08-09 1996-10-08 Regents Of The University Of California Amino-acyl-type and catecholamine-type contrast agents for MRI
US5385719A (en) * 1991-09-24 1995-01-31 Unger; Evan C. Copolymers and their use as contrast agents in magnetic resonance imaging and in other applications
US5508388A (en) * 1992-07-16 1996-04-16 Mallinckrodt Medical, Inc. Process for manufacturing DTPA-bis amide magnetic resonance imaging
AU5360994A (en) * 1992-10-13 1994-05-09 Mallinckrodt Medical, Inc. Novel compositions for magnetic resonance imaging
EP0664713B1 (en) * 1992-10-14 2000-01-19 Nycomed Imaging As Therapeutic and diagnostic imaging compositions and methods
KR950703582A (ko) * 1992-10-14 1995-09-20 조이스 이. 마임스 킬레이트화 중합체(chelating polymers)
US5817292A (en) * 1992-10-14 1998-10-06 Nycomed Imaging As MR imaging compositions and methods
PT661279E (pt) * 1993-12-30 2001-06-29 Guerbet Sa Ligandos poliaminados complexos metalicos processo de preparacao aplicacoes em diagnostico e terapeuticas
US5582814A (en) * 1994-04-15 1996-12-10 Metasyn, Inc. 1-(p-n-butylbenzyl) DTPA for magnetic resonance imaging
TW319763B (enExample) * 1995-02-01 1997-11-11 Epix Medical Inc
US5804164A (en) * 1996-03-13 1998-09-08 Research Corporation Technologies, Inc. Water-soluble lipophilic contrast agents
US5820851A (en) * 1997-08-21 1998-10-13 Hoechst Celanese Corporation Tripodal pyridine ligands as MRI contrast agents
US5824288A (en) * 1997-08-21 1998-10-20 Hoechst Celanese Corporation Thio-substituted pyridines as MRI ligand precursors
US5858329A (en) * 1997-08-21 1999-01-12 Hoechst Celanese Corporation MRI diagnostic procedures using tripodal pyridinyl metal complexes
US5869026A (en) * 1997-08-21 1999-02-09 Hoechst Celanese Corp. Tripodal carboxamide ligands for MRI contrast agents
US5869025A (en) * 1997-08-21 1999-02-09 Hoechst Celanese Corporation Tripodal aromatic heterocycle carboxamide MRI contrast agents
EP0953360B1 (en) * 1998-03-24 2004-05-26 Council of Scientific and Industrial Research Technetium-99m radiolabelled diethylene triamine pentaacetic acid diester and process for the preparation of technetium-99m diethylene triamine penta-acetic acid diester
US8669236B2 (en) * 2005-05-12 2014-03-11 The General Hospital Corporation Biotinylated compositions
US8030358B2 (en) * 2007-10-29 2011-10-04 University Of Kentucky Research Foundation Methods and pharmaceutical compositions for decorporation of radioactive compounds
US9655977B2 (en) 2012-08-31 2017-05-23 The General Hospital Corporation Biotin complexes for treatment and diagnosis of alzheimer's disease

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3129906C3 (de) * 1981-07-24 1996-12-19 Schering Ag Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik
FR2550449B1 (fr) * 1983-08-12 1986-01-31 Commissariat Energie Atomique Agents de relaxation specifiques d'organes ou de pathologies, utilisables pour modifier les contrastes en imagerie medicale par resonance magnetique nucleaire

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3401052A1 (de) * 1983-01-21 1984-07-26 Schering AG, 1000 Berlin und 4709 Bergkamen Diagnostische mittel
DE3401052C2 (de) * 1983-01-21 2001-05-23 Schering Ag Diagnostische Mittel
DE3710730A1 (de) * 1987-03-31 1988-10-20 Schering Ag Substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel

Also Published As

Publication number Publication date
EP0200750A4 (en) 1989-07-25
WO1986002005A1 (en) 1986-04-10
US4687658A (en) 1987-08-18
GB2177086A (en) 1987-01-14
GB8613493D0 (en) 1986-07-09
JPS62501288A (ja) 1987-05-21
EP0200750A1 (en) 1986-11-12
EP0200750B1 (en) 1993-01-07
GB2177086B (en) 1988-06-08

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: SALUTAR, INC., LOS ALTOS, CALIF., US

8141 Disposal/no request for examination
8110 Request for examination paragraph 44
8125 Change of the main classification

Ipc: A61K 49/00

8607 Notification of search results after publication
8136 Disposal/non-payment of the fee for publication/grant