DE3578613D1 - Verfahren zur reinigung des influenzavirus. - Google Patents

Verfahren zur reinigung des influenzavirus.

Info

Publication number
DE3578613D1
DE3578613D1 DE8585110012T DE3578613T DE3578613D1 DE 3578613 D1 DE3578613 D1 DE 3578613D1 DE 8585110012 T DE8585110012 T DE 8585110012T DE 3578613 T DE3578613 T DE 3578613T DE 3578613 D1 DE3578613 D1 DE 3578613D1
Authority
DE
Germany
Prior art keywords
influenza virus
cleaning
influence virus
virus
chromatography
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585110012T
Other languages
German (de)
English (en)
Inventor
Tetsuya Oka
Kunio Ohkuma
Tetsuo Kawahara
Mitsuo Sakoh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemo Sero Therapeutic Research Institute Kaketsuken
Original Assignee
Chemo Sero Therapeutic Research Institute Kaketsuken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeutic Research Institute Kaketsuken filed Critical Chemo Sero Therapeutic Research Institute Kaketsuken
Application granted granted Critical
Publication of DE3578613D1 publication Critical patent/DE3578613D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16151—Methods of production or purification of viral material

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8585110012T 1984-08-09 1985-08-08 Verfahren zur reinigung des influenzavirus. Expired - Lifetime DE3578613D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59167324A JPS6147186A (ja) 1984-08-09 1984-08-09 インフルエンザウイルスの精製方法

Publications (1)

Publication Number Publication Date
DE3578613D1 true DE3578613D1 (de) 1990-08-16

Family

ID=15847633

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585110012T Expired - Lifetime DE3578613D1 (de) 1984-08-09 1985-08-08 Verfahren zur reinigung des influenzavirus.

Country Status (7)

Country Link
US (1) US4724210A (en:Method)
EP (1) EP0171086B1 (en:Method)
JP (1) JPS6147186A (en:Method)
KR (1) KR920009733B1 (en:Method)
AT (1) ATE54468T1 (en:Method)
CA (1) CA1251399A (en:Method)
DE (1) DE3578613D1 (en:Method)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
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US5215739A (en) * 1989-04-05 1993-06-01 Toko Yakuhin Kogyo Kabushiki Kaisha Spray gel base and spray gel preparation using thereof
US5158761A (en) * 1989-04-05 1992-10-27 Toko Yakuhin Kogyo Kabushiki Kaisha Spray gel base and spray gel preparation using thereof
FR2667622B1 (fr) * 1990-10-08 1994-10-07 Kaysersberg Sa Montisse lie hydrauliquement et son procede de fabrication.
IT1248075B (it) * 1991-06-18 1995-01-05 Sclavo Spa Processo per la purificazione del virus dell'epatite a (hav), virus cosi` purificato e composizioni vaccinali che lo contengono.
US5447859A (en) * 1993-07-16 1995-09-05 Viagene Method for the purification or removal of retroviruses using sulfated cellulose
EP1010981A1 (de) * 1998-12-18 2000-06-21 Diagor GmbH Konjugate zum Nachweis von Viren und deren Verwendung
JP2002142770A (ja) 2000-11-08 2002-05-21 Dnavec Research Inc 循環系への遺伝子送達用パラミクソウイルスベクター
PL354822A1 (en) * 2002-06-30 2004-01-12 Instytut Immunologii i Terapii Doświadczalnej PANwe Wrocławiu Method of receiving purified bacteriophage preparations and new applications of polysaccharide or its esterificated derivative
AU2004249199B2 (en) * 2003-06-18 2008-07-24 Onyx Pharmaceuticals, Inc. Method for purifying virus
CA2503774C (en) * 2003-06-20 2007-09-25 Microbix Biosystems Inc. Improvements in virus production
KR101279748B1 (ko) 2003-11-04 2013-07-04 가부시키가이샤 디나벡크 겐큐쇼 유전자 도입된 수상세포의 제조방법
US20110162093A1 (en) 2005-06-14 2011-06-30 Yasuji Ueda Methods for producing antibodies
AU2006285306B2 (en) * 2005-07-25 2012-07-19 Avianax, Llc. Therapeutic antibodies for treatment and prophylaxis of transmittable viral diseases
US8877187B2 (en) * 2005-07-25 2014-11-04 Avianax, Llc Therapeutic antibodies for treatment and prophylaxis of transmittable viral diseases
EP1808697A1 (en) * 2006-01-13 2007-07-18 Novartis Vaccines and Diagnostics, Inc. Use of an ion exchange matrix for determining the concentration of virus particles and/or virus antigens
EP1983048A4 (en) 2006-01-17 2009-04-22 Dnavec Corp NEW PROTEIN EXPRESSION SYSTEM
WO2007146197A1 (en) * 2006-06-09 2007-12-21 Xing-Xiang Li Methods and reagents for virus isolation and detection
EP1878791A1 (en) 2006-07-11 2008-01-16 Bia Separations D.O.O. Method for influenza virus purification
KR20090052857A (ko) 2006-07-13 2009-05-26 디나벡크 가부시키가이샤 비복제형 파라믹소바이러스과 바이러스 벡터
WO2008039136A1 (en) * 2006-09-29 2008-04-03 Ge Healthcare Bio-Sciences Ab Separation matrix for viral purification
EP1982727A1 (en) * 2007-04-17 2008-10-22 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method for purification of viral proteins
WO2008136438A1 (ja) 2007-04-27 2008-11-13 Kyushu University, National University Corporation 遺伝子治療用ウイルスベクター
US20090098143A1 (en) * 2007-06-29 2009-04-16 Avianax, Inc. Vaccine production for pathogenic bird viral diseases
JP5389342B2 (ja) * 2007-08-09 2014-01-15 デンカ生研株式会社 吸着担体及び吸着担体の製造方法
JP5716297B2 (ja) 2009-06-25 2015-05-13 Jnc株式会社 クロマトグラフィー用充填剤、その製造方法、およびそれを用いたウイルス用ワクチンの製造方法
WO2011130119A2 (en) 2010-04-14 2011-10-20 Millipore Corporation Methods of producing high titer, high purity virus stocks and methods of use thereof
MY178616A (en) 2012-09-17 2020-10-19 Grace W R & Co Chromatography media and devices
US11685793B2 (en) 2013-09-02 2023-06-27 Jnc Corporation Method for producing porous cellulose particles, and porous cellulose particles
DE102013017014B4 (de) 2013-10-14 2017-03-30 Sartorius Stedim Biotech Gmbh Sulfatierte Cellulosehydrat-Membran, Verfahren zur ihrer Herstellung und Verwendung der Membran als Adsorptionsmembran für die Virenaufreinigung
CN107847907A (zh) 2014-05-02 2018-03-27 格雷斯公司 官能化载体材料以及制备和使用官能化载体材料的方法
EP2966093A1 (en) 2014-07-07 2016-01-13 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Process for the preparation of magnetic sulfated cellulose particles, magnetic sulfated cellulose particles and their use
BR112017026193B1 (pt) 2015-06-05 2021-09-14 W.R. Grace & Co-Conn Adsorventes, método de produção dos adsorventes e uso dos adsorventes
US10626376B2 (en) 2016-11-14 2020-04-21 St. Jude Children's Research Hospital Method for isolating and purifying adeno-associated virus particles using salt
CN106622159B (zh) * 2016-12-22 2019-06-14 苏州楚博生物技术有限公司 用于蛋白药物纯化的亲和层析介质

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL131092C (en:Method) *
US3105012A (en) * 1961-10-19 1963-09-24 Parke Davis & Co Antigen products and means for producing the same
BE662899A (en:Method) * 1964-04-22
US3547779A (en) * 1968-12-18 1970-12-15 Merck & Co Inc Process for producing purified concentrated influenza virus
SE356735B (en:Method) * 1970-12-02 1973-06-04 Svenska Cellulosa Ab
US3842062A (en) * 1972-09-27 1974-10-15 Du Pont Water-soluble complexes of protein and anionic polyelectrolytes such as sodium carboxymethyl cellulose
US3920625A (en) * 1973-06-19 1975-11-18 Kabi Ab Isolation of coagulation factors from biological material using cross linked sulfated, sulfonated carbohydrates
US4160018A (en) * 1973-06-25 1979-07-03 Bjorklund Knut B Stabilized cancer associated polypeptide antigen and preparation thereof
IL49752A (en) * 1975-07-09 1979-07-25 Kabi Ab Compositions having affinity for hepatitis virus and method for hepatitis virus removal or concentration
SE420977B (sv) * 1976-03-18 1981-11-16 Kabi Ab Forfarande for rening och isolering av hepatitvirus for vaccinframstellning
US4181713A (en) * 1978-10-30 1980-01-01 Merck & Co., Inc. Isolation of HBs Ag
DE3014189A1 (de) * 1980-04-14 1981-10-15 Europäisches Laboratorium für Molekularbiologie (EMBL), 6900 Heidelberg Verfahren zur herstellung eines immunogenen membranproteinaggregats von influenza-, parainfluenza- und rhabdo-viren
JPS57136528A (en) * 1981-02-09 1982-08-23 Hayashibara Biochem Lab Inc Preparation of viral vaccine
US4434093A (en) * 1982-07-26 1984-02-28 Ortho Diagnostic Systems Inc. Methods for preparation of HBs Ag free gamma globulins
US4515714A (en) * 1983-03-09 1985-05-07 Juridicial Foundation, The Chemo-Semo-Sero-Therapeutic Research Institute Method for purification of hepatitis B virus surface antigen

Also Published As

Publication number Publication date
JPS6230752B2 (en:Method) 1987-07-03
US4724210A (en) 1988-02-09
KR870001835A (ko) 1987-03-28
EP0171086A2 (en) 1986-02-12
JPS6147186A (ja) 1986-03-07
CA1251399A (en) 1989-03-21
ATE54468T1 (de) 1990-07-15
EP0171086A3 (en) 1988-01-13
KR920009733B1 (ko) 1992-10-22
EP0171086B1 (en) 1990-07-11

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