DE3570665D1 - Benzofuran derivatives, processes for preparing the same and antihypertensive agents containing the same - Google Patents

Benzofuran derivatives, processes for preparing the same and antihypertensive agents containing the same

Info

Publication number
DE3570665D1
DE3570665D1 DE8585103436T DE3570665T DE3570665D1 DE 3570665 D1 DE3570665 D1 DE 3570665D1 DE 8585103436 T DE8585103436 T DE 8585103436T DE 3570665 T DE3570665 T DE 3570665T DE 3570665 D1 DE3570665 D1 DE 3570665D1
Authority
DE
Germany
Prior art keywords
same
group
preparing
processes
effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8585103436T
Other languages
English (en)
Inventor
Jun Nakano
Michiko Nagahara
Mitsuo Hayashida
Yuji Suzuki
Yohichi Maruyama
Toshimitsu Hori
Akira Sakai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kaken Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaken Pharmaceutical Co Ltd filed Critical Kaken Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3570665D1 publication Critical patent/DE3570665D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8585103436T 1984-03-27 1985-03-22 Benzofuran derivatives, processes for preparing the same and antihypertensive agents containing the same Expired DE3570665D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59060399A JPS60202872A (ja) 1984-03-27 1984-03-27 ベンゾフラン誘導体、その製法およびそれを有効成分とする降圧剤

Publications (1)

Publication Number Publication Date
DE3570665D1 true DE3570665D1 (en) 1989-07-06

Family

ID=13141043

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585103436T Expired DE3570665D1 (en) 1984-03-27 1985-03-22 Benzofuran derivatives, processes for preparing the same and antihypertensive agents containing the same

Country Status (6)

Country Link
US (1) US4652566A (de)
EP (1) EP0156331B1 (de)
JP (1) JPS60202872A (de)
AT (1) ATE43588T1 (de)
DE (1) DE3570665D1 (de)
ES (1) ES8606321A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG65570A1 (en) * 1992-02-25 1999-06-22 Recordati Chem Pharm Heterobicyclic compounds
CN1040434C (zh) * 1992-05-26 1998-10-28 瑞柯戴堤化学制药公司 杂二环化合物
DK0703911T3 (da) * 1993-06-14 1997-10-06 Pfizer Sekundære aminer som antidiabetiske og antiobesitetsmidler
KR100799134B1 (ko) 1999-05-24 2008-01-29 미츠비시 웰파마 가부시키가이샤 페녹시프로필아민 화합물
AU2002224105A1 (en) * 2000-11-27 2002-06-03 Mitsubishi Pharma Corporation Piperidine compounds and medicinal use thereof
US7709510B2 (en) * 2001-02-20 2010-05-04 Chugai Seiyaku Kabushiki Kaisha Azoles as malonyl-CoA decarboxylase inhibitors useful as metabolic modulators
US7723366B2 (en) * 2001-02-20 2010-05-25 Chugai Seiyaku Kabushiki Kaisha Azole compounds as malonyl-CoA decarboxylase inhibitors for treating metabolic diseases
US7425517B2 (en) * 2003-07-25 2008-09-16 Kimberly-Clark Worldwide, Inc. Nonwoven fabric with abrasion resistance and reduced surface fuzziness
CA2533747C (en) * 2003-08-01 2012-11-13 Chugai Seiyaku Kabushiki Kaisha Heterocyclic compounds useful as malonyl-coa decarboxylase inhibitors
ES2314491T3 (es) * 2003-08-01 2009-03-16 Chugai Seiyaku Kabushiki Kaisha Compuestos azol basados en cianoguanidina utiles como inhibidores de la manonil-coa descaraboxilasa.
US7449482B2 (en) * 2003-08-01 2008-11-11 Chugai Seiyaku Kabushiki Kaisha Piperidine compounds useful as malonyl-CoA decarboxylase inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853923A (en) * 1971-05-13 1974-12-10 Kakenyaku Kako Kk 2-substituted-(2-hydroxy-3-lower alkaminopropoxy)-benzofurans
GB1493998A (en) * 1975-06-03 1977-12-07 Beecham Group Ltd Propanolamine derivatives
CA1089866A (en) * 1975-10-20 1980-11-18 Kiyoshi Ito Benzofuran derivatives, preparation thereof and pharmaceutical compositions thereof
FR2447378A1 (fr) * 1979-01-23 1980-08-22 Delalande Sa Nouveaux derives n-arylpiperazinoalcoxy-6 dimethoxy-4,7 benzofurannes, leur procede de preparation et leur application en therapeutique
FR2449088A1 (fr) * 1979-02-14 1980-09-12 Delalande Sa Nouveaux derives du benzodioxanne portant en position 5 du noyau benzodioxanne un enchainement n-arylpiperazinopropyl (ou hydroxy-2 propyl) oxy, leurs procedes de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
JPS60202872A (ja) 1985-10-14
ES8606321A1 (es) 1986-04-01
EP0156331B1 (de) 1989-05-31
EP0156331A2 (de) 1985-10-02
US4652566A (en) 1987-03-24
EP0156331A3 (en) 1986-08-20
JPS6140674B2 (de) 1986-09-10
ES541573A0 (es) 1986-04-01
ATE43588T1 (de) 1989-06-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee