DE3569237D1 - Cancer chemotherapeutic cyclic and acyclic disulfonic ester compounds, method of use therefor, and intermediates - Google Patents

Cancer chemotherapeutic cyclic and acyclic disulfonic ester compounds, method of use therefor, and intermediates

Info

Publication number
DE3569237D1
DE3569237D1 DE8585900874T DE3569237T DE3569237D1 DE 3569237 D1 DE3569237 D1 DE 3569237D1 DE 8585900874 T DE8585900874 T DE 8585900874T DE 3569237 T DE3569237 T DE 3569237T DE 3569237 D1 DE3569237 D1 DE 3569237D1
Authority
DE
Germany
Prior art keywords
acyclic
intermediates
cyclic
ester compounds
cancer chemotherapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8585900874T
Other languages
German (de)
English (en)
Inventor
Marshall W Cronyn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE3569237D1 publication Critical patent/DE3569237D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0834—Compounds having one or more O-Si linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8585900874T 1984-01-16 1985-01-14 Cancer chemotherapeutic cyclic and acyclic disulfonic ester compounds, method of use therefor, and intermediates Expired DE3569237D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/570,786 US4950768A (en) 1984-01-16 1984-01-16 Cyclic disulfonic ester cross-linking compounds
PCT/US1985/000057 WO1985003075A1 (en) 1984-01-16 1985-01-14 Cancer chemotherapeutic cyclic and acyclic disulfonic ester compounds, method of use therefor, and intermediates

Publications (1)

Publication Number Publication Date
DE3569237D1 true DE3569237D1 (en) 1989-05-11

Family

ID=24281052

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585900874T Expired DE3569237D1 (en) 1984-01-16 1985-01-14 Cancer chemotherapeutic cyclic and acyclic disulfonic ester compounds, method of use therefor, and intermediates

Country Status (6)

Country Link
US (1) US4950768A (cg-RX-API-DMAC7.html)
EP (1) EP0168478B1 (cg-RX-API-DMAC7.html)
JP (1) JPS61501089A (cg-RX-API-DMAC7.html)
CA (1) CA1246087A (cg-RX-API-DMAC7.html)
DE (1) DE3569237D1 (cg-RX-API-DMAC7.html)
WO (1) WO1985003075A1 (cg-RX-API-DMAC7.html)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849482A (en) * 1988-09-28 1998-12-15 Epoch Pharmaceuticals, Inc. Crosslinking oligonucleotides
USRE38416E1 (en) 1988-09-28 2004-02-03 Epoch Biosciences, Inc. Cross-linking oligonucleotides
US5824796A (en) * 1988-09-28 1998-10-20 Epoch Pharmaceuticals, Inc. Cross-linking oligonucleotides
JPH04507402A (ja) * 1989-05-18 1992-12-24 マイクロプローブ・コーポレーション 架橋オリゴヌクレオチド
US6136601A (en) * 1991-08-21 2000-10-24 Epoch Pharmaceuticals, Inc. Targeted mutagenesis in living cells using modified oligonucleotides
ES2395515T3 (es) * 1997-11-10 2013-02-13 Memorial Sloan Kettering Cancer Center Trióxido de arsénico para uso en el tratamiento de la leucemia
JP4033074B2 (ja) 2002-08-29 2008-01-16 日本電気株式会社 二次電池用電解液およびそれを用いた二次電池
CN100395905C (zh) 2003-09-16 2008-06-18 日本电气株式会社 非水性电解液二次电池
WO2005057714A1 (ja) 2003-12-15 2005-06-23 Nec Corporation 二次電池用電解液およびそれを用いた二次電池
JP4725728B2 (ja) * 2003-12-15 2011-07-13 日本電気株式会社 二次電池
JP4588407B2 (ja) * 2004-04-28 2010-12-01 住友化学株式会社 環式ジスルホン酸エステルの製造方法
JP2006188449A (ja) * 2005-01-05 2006-07-20 Sumitomo Chemical Co Ltd 環式ジスルホン酸エステルの製造方法
JP4577499B2 (ja) * 2005-01-28 2010-11-10 日本電気株式会社 メチレンジスルホニルクロライド及びその誘導体の製造方法
TWI410413B (zh) * 2006-04-26 2013-10-01 Sumitomo Seika Chemicals Preparation method of methylene disulfonate compound
TWI401250B (zh) * 2006-06-19 2013-07-11 Wako Pure Chem Ind Ltd 環狀二磺酸酯之製造方法
KR101407331B1 (ko) 2006-09-12 2014-06-13 와코 쥰야꾸 고교 가부시키가이샤 술폰산에스테르의 제조방법
US8124793B2 (en) * 2007-11-27 2012-02-28 Gail Marie Cronyn, legal representative Derivatives of ethylene methanedisulfonate as cancer chemotherapeutic agents
JP5169400B2 (ja) * 2008-04-07 2013-03-27 Ｎｅｃエナジーデバイス株式会社 非水電解液およびそれを用いた非水電解液二次電池
JP5408702B2 (ja) 2009-01-23 2014-02-05 Ｎｅｃエナジーデバイス株式会社 リチウムイオン電池
JP5305446B2 (ja) * 2009-03-19 2013-10-02 Ｎｅｃエナジーデバイス株式会社 非水電解液およびそれを用いた非水電解液二次電池
CN102473966A (zh) 2009-07-09 2012-05-23 Nec能源元器件株式会社 聚合物凝胶电解质和使用它的聚合物二次电池
EP2535974B1 (en) 2010-02-08 2016-10-26 NEC Energy Devices, Ltd. Nonaqueous electrolyte secondary battery
CN102742064B (zh) 2010-02-10 2015-11-25 Nec能源元器件株式会社 非水性电解质溶液，和具有所述非水性电解质溶液的锂离子二次电池
TWI508956B (zh) 2010-08-25 2015-11-21 Sumitomo Seika Chemicals Preparation method of methylene disulfonate compound
JP5724366B2 (ja) * 2010-12-21 2015-05-27 セントラル硝子株式会社 環状ジスルホン酸エステル化合物の製造方法
KR20220041092A (ko) 2019-07-23 2022-03-31 스미토모 세이카 가부시키가이샤 메틸렌디설포네이트 화합물의 제조 방법
US11802119B2 (en) 2019-07-23 2023-10-31 Sumitomo Seika Chemicals Co., Ltd. Method for producing cyclic disulfonic acid ester compound
CN112574167B (zh) * 2020-12-07 2021-11-09 烟台海川化学制品有限公司 一种甲烷二磺酸亚甲酯的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB700677A (en) * 1950-05-09 1953-12-09 Wellcome Found Improvements in or relating to aliphatic sulphonic acid esters of therapeutic value
AT210874B (de) * 1959-02-13 1960-08-25 Leuna Werke Veb Verfahren zur Herstellung von neuen Polysulfosäureestern
DE1124032B (de) * 1960-06-25 1962-02-22 Basf Ag Verfahren zur Herstellung von Salzen der Halbester der AEthandisulfonsaeure
DE1277247B (de) * 1965-12-08 1968-09-12 Basf Ag Verfahren zur Herstellung von Vinylsulfonsaeurealkylestern
DE3004692A1 (de) * 1980-02-08 1981-08-13 Agfa-Gevaert Ag, 5090 Leverkusen Hydroxyalkansulfonsaeure-sulfoalkylester

Also Published As

Publication number Publication date
CA1246087A (en) 1988-12-06
EP0168478A4 (en) 1986-11-07
JPH0544946B2 (cg-RX-API-DMAC7.html) 1993-07-07
US4950768A (en) 1990-08-21
WO1985003075A1 (en) 1985-07-18
JPS61501089A (ja) 1986-05-29
EP0168478A1 (en) 1986-01-22
EP0168478B1 (en) 1989-04-05

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee