DE3567454D1 - Leukotriene antagonists - Google Patents

Leukotriene antagonists

Info

Publication number
DE3567454D1
DE3567454D1 DE8585304111T DE3567454T DE3567454D1 DE 3567454 D1 DE3567454 D1 DE 3567454D1 DE 8585304111 T DE8585304111 T DE 8585304111T DE 3567454 T DE3567454 T DE 3567454T DE 3567454 D1 DE3567454 D1 DE 3567454D1
Authority
DE
Germany
Prior art keywords
hydrogen
alkyl
alkenyl
chem
ch2oh
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8585304111T
Other languages
English (en)
Inventor
William Edward Bondinell
David Taylor Hill
Barry Michael Weichman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Application granted granted Critical
Publication of DE3567454D1 publication Critical patent/DE3567454D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8585304111T 1984-06-18 1985-06-11 Leukotriene antagonists Expired DE3567454D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62140784A 1984-06-18 1984-06-18

Publications (1)

Publication Number Publication Date
DE3567454D1 true DE3567454D1 (en) 1989-02-16

Family

ID=24490051

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585304111T Expired DE3567454D1 (en) 1984-06-18 1985-06-11 Leukotriene antagonists

Country Status (11)

Country Link
EP (1) EP0168950B1 (de)
JP (1) JPS6112673A (de)
AT (1) ATE39922T1 (de)
AU (1) AU578101B2 (de)
CA (1) CA1242732A (de)
DE (1) DE3567454D1 (de)
DK (1) DK275285A (de)
ES (5) ES8700659A1 (de)
GR (1) GR851449B (de)
PT (1) PT80651B (de)
ZA (1) ZA854550B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3508665A1 (de) * 1985-03-12 1986-09-18 Hoechst Ag, 6230 Frankfurt Heterocyclische sulfide und ihre anwendung als immunmodulatoren
US4990526A (en) * 1985-06-18 1991-02-05 Merck Frosst Canada, Inc. Leukotriene antagonists, compositions and methods of use thereof
US4900744A (en) * 1988-09-14 1990-02-13 E. I. Du Pont De Nemours And Company Antihypercholesterolemic 4,5-diaryl-2-substituted thioimidazoles

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4311645A (en) * 1980-03-24 1982-01-19 Hoffmann-La Roche Inc. Synthesis of SRS-active compounds
DE3107599C2 (de) * 1981-02-27 1982-12-16 Ludwig Heumann & Co GmbH, 8500 Nürnberg N-Cyan-N'-methyl-N"-{2-[(5-methylthio-imidazol-4-yl)-methylthio]-äthyl}-guanidin, Verfahren zu seiner Herstellung und diese Verbindung enthaltende Arzneimittel

Also Published As

Publication number Publication date
PT80651A (en) 1985-07-01
PT80651B (en) 1987-04-28
ES8707198A1 (es) 1987-07-01
ES544268A0 (es) 1986-10-16
ES8707197A1 (es) 1987-07-01
ES8707199A1 (es) 1987-07-01
DK275285A (da) 1985-12-19
ES555618A0 (es) 1987-07-01
EP0168950B1 (de) 1989-01-11
ZA854550B (en) 1986-04-30
ATE39922T1 (de) 1989-01-15
GR851449B (de) 1985-11-25
DK275285D0 (da) 1985-06-18
ES555616A0 (es) 1987-07-01
ES555619A0 (es) 1987-07-01
ES8700659A1 (es) 1986-10-16
AU578101B2 (en) 1988-10-13
ES555617A0 (es) 1987-07-01
EP0168950A1 (de) 1986-01-22
CA1242732A (en) 1988-10-04
ES8707196A1 (es) 1987-07-01
JPS6112673A (ja) 1986-01-21
AU4367685A (en) 1986-01-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee