ES8404974A1 - Un procedimiento para la preparacion de eteres alquil-naftilicos. - Google Patents

Un procedimiento para la preparacion de eteres alquil-naftilicos.

Info

Publication number
ES8404974A1
ES8404974A1 ES518136A ES518136A ES8404974A1 ES 8404974 A1 ES8404974 A1 ES 8404974A1 ES 518136 A ES518136 A ES 518136A ES 518136 A ES518136 A ES 518136A ES 8404974 A1 ES8404974 A1 ES 8404974A1
Authority
ES
Spain
Prior art keywords
naphthoxyalkylamines
preparation
compositions containing
related compounds
antiinflammatory compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES518136A
Other languages
English (en)
Other versions
ES518136A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of ES8404974A1 publication Critical patent/ES8404974A1/es
Publication of ES518136A0 publication Critical patent/ES518136A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/26Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/30Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/202Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a naphthalene
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE ETERES ALQUIL-NAFTILICOS.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UNA AMINA SUSTITUIDA O UN COMPUESTO DE FORMULA (III) PARA DAR ETERES ALQUIL-NAFTILICOS DE FORMULA (I), Y SUS SALES DE ADICION DE ACIDO, EN DONDE Y ES HALOGENO, ALCOXILO O ALQUILO; A ES 0 O 1; B ES UN NUMERO ENTERO DE 2 A 12; X ES UN GRUPO SUSTITUIDO POR -NH2, -NHR, -OH, -OR Y OTROS; Y R ES ALQUILO O FENILO.PRESENTAN APLICACION FARMACEUTICA POR SU ACTIVIDAD ANTIINFLAMATORIA.
ES518136A 1981-12-14 1982-12-13 Un procedimiento para la preparacion de eteres alquil-naftilicos. Granted ES518136A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33011481A 1981-12-14 1981-12-14

Publications (2)

Publication Number Publication Date
ES8404974A1 true ES8404974A1 (es) 1984-06-01
ES518136A0 ES518136A0 (es) 1984-06-01

Family

ID=23288374

Family Applications (1)

Application Number Title Priority Date Filing Date
ES518136A Granted ES518136A0 (es) 1981-12-14 1982-12-13 Un procedimiento para la preparacion de eteres alquil-naftilicos.

Country Status (6)

Country Link
EP (1) EP0082005A3 (es)
JP (1) JPS58113140A (es)
AU (1) AU9145782A (es)
DK (1) DK553582A (es)
ES (1) ES518136A0 (es)
ZA (1) ZA829151B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3233828A1 (de) * 1982-09-11 1984-03-15 Basf Ag, 6700 Ludwigshafen Aryloxyalkylamine, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses
EP0157652A1 (en) * 1984-04-06 1985-10-09 Syntex (U.S.A.) Inc. 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them
ZA863425B (en) * 1985-05-08 1988-01-27 Du Pont 2-substituted-1-naphthols as 5-lipoxygenase inhibitors
US5026759A (en) * 1985-05-08 1991-06-25 Du Pont Merck Pharmaceutical 2-substituted-1-naphthols as 5-lipoxygenase inhibitors
US4833164A (en) 1985-05-08 1989-05-23 E. I. Du Pont De Nemours And Company 2-substituted-1-naphthols, pharmaceutical compositions of, and their use as 5-lipoxygenase inhibitors
CA2005990C (en) * 1988-12-21 1999-12-28 Roger Alan Parker Antiretroviral aryloxy substituted furan ketones
EP0637303A1 (en) * 1992-04-24 1995-02-08 Smithkline Beecham Plc N-aryloxy(thio)alkyl-azacycloalkanes useful as calcium channel antagonists
GB9220735D0 (en) * 1992-10-02 1992-11-18 British Tech Group Heterocyclic amines
GB0023467D0 (en) * 2000-09-25 2000-11-08 Btg Int Ltd Amine compounds
AU2013350311B2 (en) * 2012-11-21 2018-03-22 The University Of Sydney Omega-3 analogues

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5638713B2 (es) * 1973-11-26 1981-09-08
US4260816A (en) * 1975-12-09 1981-04-07 American Cyanamid Company Naphthyloxyalkylaminobenzoic acids, salts and esters thereof
DE2940765A1 (de) * 1979-10-08 1981-04-23 Basf Ag, 6700 Ludwigshafen Substituierte alkylammoniumsalze, ihre herstellung, ihre verwendung zur regulierung des pflanzenwachstums und mittel dafuer

Also Published As

Publication number Publication date
EP0082005A3 (en) 1983-08-03
AU9145782A (en) 1983-06-23
ZA829151B (en) 1984-07-25
ES518136A0 (es) 1984-06-01
JPS58113140A (ja) 1983-07-05
EP0082005A2 (en) 1983-06-22
DK553582A (da) 1983-06-15

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