ES8707197A1 - Un procedimiento para preparar derivados de tioimidazol - Google Patents
Un procedimiento para preparar derivados de tioimidazolInfo
- Publication number
- ES8707197A1 ES8707197A1 ES555617A ES555617A ES8707197A1 ES 8707197 A1 ES8707197 A1 ES 8707197A1 ES 555617 A ES555617 A ES 555617A ES 555617 A ES555617 A ES 555617A ES 8707197 A1 ES8707197 A1 ES 8707197A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- alkyl
- alkenyl
- chem
- ch2oh
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR DERIVADOS DE TIOIMIDAZOL. CONSISTE EN HACER REACCIONAR A UN 4-TIOIMIDAZOL DE FORMULA (II) CON UN EPOXIALQUINOATO DE FORMULA (III), EN PRESENCIA DE ALQUILAMINA TERCIARIA, EN ALCOHOL Y A TEMPERATURA AMBIENTE, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. SIENDO: R, UN GRUPO DE FORMULA (IV); R4 Y R5, H O ALQUILO DE C 1 A 4 Y OTROS; Y M, 9 A 13. SE UTILIZAN PARA TRATAR EL ASMA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62140784A | 1984-06-18 | 1984-06-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES555617A0 ES555617A0 (es) | 1987-07-01 |
ES8707197A1 true ES8707197A1 (es) | 1987-07-01 |
Family
ID=24490051
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES544268A Expired ES8700659A1 (es) | 1984-06-18 | 1985-06-17 | Un procedimiento para preparar derivados de tioimidazol |
ES555618A Expired ES8707198A1 (es) | 1984-06-18 | 1986-06-02 | Un procedimiento para preparar derivados de tioimidazol |
ES555616A Expired ES8707196A1 (es) | 1984-06-18 | 1986-06-02 | Un procedimiento para preparar derivados de tioimidazol |
ES555619A Expired ES8707199A1 (es) | 1984-06-18 | 1986-06-02 | Un procedimiento para preparar derivados de tioimidazol |
ES555617A Expired ES8707197A1 (es) | 1984-06-18 | 1986-06-02 | Un procedimiento para preparar derivados de tioimidazol |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES544268A Expired ES8700659A1 (es) | 1984-06-18 | 1985-06-17 | Un procedimiento para preparar derivados de tioimidazol |
ES555618A Expired ES8707198A1 (es) | 1984-06-18 | 1986-06-02 | Un procedimiento para preparar derivados de tioimidazol |
ES555616A Expired ES8707196A1 (es) | 1984-06-18 | 1986-06-02 | Un procedimiento para preparar derivados de tioimidazol |
ES555619A Expired ES8707199A1 (es) | 1984-06-18 | 1986-06-02 | Un procedimiento para preparar derivados de tioimidazol |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0168950B1 (es) |
JP (1) | JPS6112673A (es) |
AT (1) | ATE39922T1 (es) |
AU (1) | AU578101B2 (es) |
CA (1) | CA1242732A (es) |
DE (1) | DE3567454D1 (es) |
DK (1) | DK275285A (es) |
ES (5) | ES8700659A1 (es) |
GR (1) | GR851449B (es) |
PT (1) | PT80651B (es) |
ZA (1) | ZA854550B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3508665A1 (de) * | 1985-03-12 | 1986-09-18 | Hoechst Ag, 6230 Frankfurt | Heterocyclische sulfide und ihre anwendung als immunmodulatoren |
US4990526A (en) * | 1985-06-18 | 1991-02-05 | Merck Frosst Canada, Inc. | Leukotriene antagonists, compositions and methods of use thereof |
US4900744A (en) * | 1988-09-14 | 1990-02-13 | E. I. Du Pont De Nemours And Company | Antihypercholesterolemic 4,5-diaryl-2-substituted thioimidazoles |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4311645A (en) * | 1980-03-24 | 1982-01-19 | Hoffmann-La Roche Inc. | Synthesis of SRS-active compounds |
DE3107599C2 (de) * | 1981-02-27 | 1982-12-16 | Ludwig Heumann & Co GmbH, 8500 Nürnberg | N-Cyan-N'-methyl-N"-{2-[(5-methylthio-imidazol-4-yl)-methylthio]-äthyl}-guanidin, Verfahren zu seiner Herstellung und diese Verbindung enthaltende Arzneimittel |
-
1984
- 1984-06-17 ZA ZA854550A patent/ZA854550B/xx unknown
-
1985
- 1985-06-11 DE DE8585304111T patent/DE3567454D1/de not_active Expired
- 1985-06-11 EP EP85304111A patent/EP0168950B1/en not_active Expired
- 1985-06-11 AT AT85304111T patent/ATE39922T1/de not_active IP Right Cessation
- 1985-06-13 CA CA000483865A patent/CA1242732A/en not_active Expired
- 1985-06-13 GR GR851449A patent/GR851449B/el unknown
- 1985-06-14 AU AU43676/85A patent/AU578101B2/en not_active Ceased
- 1985-06-17 PT PT80651A patent/PT80651B/pt unknown
- 1985-06-17 JP JP60132890A patent/JPS6112673A/ja active Pending
- 1985-06-17 ES ES544268A patent/ES8700659A1/es not_active Expired
- 1985-06-18 DK DK275285A patent/DK275285A/da unknown
-
1986
- 1986-06-02 ES ES555618A patent/ES8707198A1/es not_active Expired
- 1986-06-02 ES ES555616A patent/ES8707196A1/es not_active Expired
- 1986-06-02 ES ES555619A patent/ES8707199A1/es not_active Expired
- 1986-06-02 ES ES555617A patent/ES8707197A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES555616A0 (es) | 1987-07-01 |
ES544268A0 (es) | 1986-10-16 |
DK275285A (da) | 1985-12-19 |
ES8707196A1 (es) | 1987-07-01 |
PT80651A (en) | 1985-07-01 |
EP0168950B1 (en) | 1989-01-11 |
ES555617A0 (es) | 1987-07-01 |
ES8707198A1 (es) | 1987-07-01 |
ES555618A0 (es) | 1987-07-01 |
DE3567454D1 (en) | 1989-02-16 |
ATE39922T1 (de) | 1989-01-15 |
DK275285D0 (da) | 1985-06-18 |
CA1242732A (en) | 1988-10-04 |
GR851449B (es) | 1985-11-25 |
JPS6112673A (ja) | 1986-01-21 |
AU4367685A (en) | 1986-01-02 |
ZA854550B (en) | 1986-04-30 |
AU578101B2 (en) | 1988-10-13 |
EP0168950A1 (en) | 1986-01-22 |
ES555619A0 (es) | 1987-07-01 |
ES8707199A1 (es) | 1987-07-01 |
PT80651B (en) | 1987-04-28 |
ES8700659A1 (es) | 1986-10-16 |
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