DE3486478D1 - Zusammensetzung zur Anwendung in einem Bestimmungsverfahren unter Verwendung von Polynukleotidsequenzen - Google Patents

Zusammensetzung zur Anwendung in einem Bestimmungsverfahren unter Verwendung von Polynukleotidsequenzen

Info

Publication number
DE3486478D1
DE3486478D1 DE3486478T DE3486478T DE3486478D1 DE 3486478 D1 DE3486478 D1 DE 3486478D1 DE 3486478 T DE3486478 T DE 3486478T DE 3486478 T DE3486478 T DE 3486478T DE 3486478 D1 DE3486478 D1 DE 3486478D1
Authority
DE
Germany
Prior art keywords
composition
nucleic acid
assay
polynucleotide sequences
analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3486478T
Other languages
English (en)
Other versions
DE3486478T2 (de
Inventor
Robert G Pergolizzi
Jannis G Stavrianopoulos
Elazar Rabbani
Dean L Engelhardt
Stan Kline
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Enzo Biochem Inc
Original Assignee
Enzo Biochem Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23954256&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3486478(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Enzo Biochem Inc filed Critical Enzo Biochem Inc
Application granted granted Critical
Publication of DE3486478D1 publication Critical patent/DE3486478D1/de
Publication of DE3486478T2 publication Critical patent/DE3486478T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
DE3486478T 1983-05-05 1984-05-04 Zusammensetzung zur Anwendung in einem Bestimmungsverfahren unter Verwendung von Polynukleotidsequenzen Expired - Lifetime DE3486478T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49192983A 1983-05-05 1983-05-05

Publications (2)

Publication Number Publication Date
DE3486478D1 true DE3486478D1 (de) 2000-12-14
DE3486478T2 DE3486478T2 (de) 2001-06-28

Family

ID=23954256

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3486400T Expired - Lifetime DE3486400T2 (de) 1983-05-05 1984-05-04 Bestimmungsmethode unter Verwendung von Polynucleotidsequenzen.
DE3486478T Expired - Lifetime DE3486478T2 (de) 1983-05-05 1984-05-04 Zusammensetzung zur Anwendung in einem Bestimmungsverfahren unter Verwendung von Polynukleotidsequenzen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE3486400T Expired - Lifetime DE3486400T2 (de) 1983-05-05 1984-05-04 Bestimmungsmethode unter Verwendung von Polynucleotidsequenzen.

Country Status (11)

Country Link
US (1) US9134302B2 (de)
EP (2) EP0128332B1 (de)
JP (1) JP2577881B2 (de)
AT (2) ATE197480T1 (de)
AU (1) AU583787B2 (de)
CA (1) CA1228811A (de)
DE (2) DE3486400T2 (de)
DK (1) DK223384A (de)
ES (2) ES8608169A1 (de)
IL (1) IL71666A (de)
NO (1) NO165975C (de)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1338856C (en) * 1983-07-05 1997-01-21 Jannis Stavrianopoulos In vivo labelling of polynucleotide sequences
US4707440A (en) * 1984-01-30 1987-11-17 Enzo Biochem, Inc. Nucleic acid hybridization assay and detectable molecules useful in such assay
AU3844485A (en) * 1984-02-09 1985-08-15 Enzo Biochem Inc. Heterologous detection of cabeled dna
GB8405437D0 (en) * 1984-03-01 1984-04-04 Amersham Int Plc Detecting polynucleotide sequences
CA1253777A (en) * 1984-06-01 1989-05-09 Robert J. Carrico Nucleic acid hybridization assay employing immobilized rna probes
FI72146C (fi) * 1985-01-02 1987-04-13 Orion Yhtymae Oy Foerfarande foer identifiering av nukleinsyror.
US4824775A (en) * 1985-01-03 1989-04-25 Molecular Diagnostics, Inc. Cells labeled with multiple Fluorophores bound to a nucleic acid carrier
GB8509367D0 (en) * 1985-04-12 1985-05-15 Amersham Int Plc Nucleic acid hybridisation
DE3680156D1 (de) * 1985-05-31 1991-08-14 Amoco Corp Verstaerkung von hybridisierungssignalen durch verwendung von komplementarischen dns-straengen.
ES8707343A1 (es) * 1985-06-13 1987-07-16 Amgen Un metodo para aislar una secuencia de acido nucleico objetivo seleccionada
US4868105A (en) * 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
US4882269A (en) * 1985-12-13 1989-11-21 Princeton University Amplified hybridization assay
US4822731A (en) * 1986-01-09 1989-04-18 Cetus Corporation Process for labeling single-stranded nucleic acids and hybridizaiton probes
US4900659A (en) * 1986-01-30 1990-02-13 Enzo Biochem, Inc. Nucleotide sequence composition and method for detection of Neisseria gonorrhoeae and method for screening for a nucleotide sequence that is specific for a genetically distinct group
US4839293A (en) * 1986-02-24 1989-06-13 The Trustees Of Columbia University In The City Of New York DNA encoding streptavidin, streptavidin produced therefrom, fused polypeptides which include amino acid sequences present in streptavidin and uses thereof
US4925785A (en) * 1986-03-07 1990-05-15 Biotechnica Diagnostics, Inc. Nucleic acid hybridization assays
US7087742B1 (en) 1986-11-24 2006-08-08 Gen-Probe Incorporated Oligonucleotide probes for the detection and/or quantitation of non-viral organisms
US7138516B1 (en) 1986-11-24 2006-11-21 Gen-Probe Incorporated Oligonucleotide probes for the detection and/or quantitation of non-viral organisms
JP2565552B2 (ja) * 1987-10-15 1996-12-18 カイロン コーポレイション 核酸マルチマーおよびそれを用いた増幅核酸ハイブリダイゼーション分析法
FR2644163B2 (fr) * 1988-07-13 1994-09-30 Bioprobe Systems Sa Procede de marquage d'une sonde nucleique et trousse de reactifs pour la mise en oeuvre de ce procede
US7172863B1 (en) 1988-12-09 2007-02-06 Gen-Probe Incorporated Nucleic acid probes and methods for detecting Neisseria gonorrhoeae
US5683874A (en) * 1991-03-27 1997-11-04 Research Corporation Technologies, Inc. Single-stranded circular oligonucleotides capable of forming a triplex with a target sequence
JPH06506603A (ja) * 1991-03-27 1994-07-28 リサーチ　コーポレーション　テクノロジーズ　インコーポレーテッド 一本鎖環状オリゴヌクレオチド
US5329461A (en) * 1992-07-23 1994-07-12 Acrogen, Inc. Digital analyte detection system
US7713528B1 (en) 1993-02-18 2010-05-11 Enzo Therapeutics, Inc. Method for in vivo delivery of active compounds using reagent conjugate
US6986985B1 (en) 1994-01-13 2006-01-17 Enzo Life Sciences, Inc. Process for producing multiple nucleic acid copies in vivo using a protein-nucleic acid construct
CA2140081C (en) 1994-01-13 2008-04-01 Dean L. Engelhardt Process, construct and conjugate for producing multiple nucleic acid copies
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
AU714486B2 (en) 1995-11-21 2000-01-06 Yale University Unimolecular segment amplification and detection
DE69719057T2 (de) * 1996-07-12 2003-12-04 Tm Technologies Inc., Woburn Verfahren zur signalverstärkung
IL131979A0 (en) 1997-03-21 2001-03-19 Enzo Therapeutics Inc Vectors and viral vectors and packaging cell lines for propagating the same
US8703480B1 (en) 1997-03-21 2014-04-22 Enzo Therapeutics, Inc. Biological function effecting viral vectors and chimeric cells useful as packaging cell lines and target cells
US6124120A (en) 1997-10-08 2000-09-26 Yale University Multiple displacement amplification
US6316229B1 (en) 1998-07-20 2001-11-13 Yale University Single molecule analysis target-mediated ligation of bipartite primers
JP2002525078A (ja) 1998-09-15 2002-08-13 イェール ユニバーシティ 人工的長末端反復配列
AU770993B2 (en) * 1998-09-15 2004-03-11 Yale University Molecular cloning using rolling circle amplification
US6613516B1 (en) 1999-10-30 2003-09-02 Affymetrix, Inc. Preparation of nucleic acid samples
US6686157B2 (en) 2000-06-30 2004-02-03 Molecular Staging Inc. Signal amplification with lollipop probes
US20040161741A1 (en) 2001-06-30 2004-08-19 Elazar Rabani Novel compositions and processes for analyte detection, quantification and amplification
JP2005515468A (ja) * 2001-08-20 2005-05-26 リジェネシス バイオリメディエイション プロダクツ 微分子の分析物のバイオセンサ
US9487823B2 (en) 2002-12-20 2016-11-08 Qiagen Gmbh Nucleic acid amplification
US8043834B2 (en) 2003-03-31 2011-10-25 Qiagen Gmbh Universal reagents for rolling circle amplification and methods of use
US7514551B2 (en) * 2003-04-03 2009-04-07 Enzo Life Sciences, Inc. Multisignal labeling reagents, and processes and uses therefor
US9696298B2 (en) 2003-04-03 2017-07-04 Enzo Life Sciences, Inc. Multisignal reagents for labeling analytes
US9156986B2 (en) 2003-04-03 2015-10-13 Enzo Life Sciences, Inc. Multisignal labeling reagents and processes and uses therefor
EP1863908B1 (de) 2005-04-01 2010-11-17 Qiagen GmbH Reverse transkription und amplifikation von rna bei simultaner degradierung von dna
EP1762627A1 (de) 2005-09-09 2007-03-14 Qiagen GmbH Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
CA2624324A1 (en) 2005-10-06 2007-04-19 Lucigen Corporation Thermostable viral polymerases and methods of use
US20090162845A1 (en) 2007-12-20 2009-06-25 Elazar Rabbani Affinity tag nucleic acid and protein compositions, and processes for using same
EP4108782B1 (de) 2011-12-22 2023-06-07 President and Fellows of Harvard College Zusammensetzungen und verfahren zur analytdetektion
WO2013134503A2 (en) 2012-03-09 2013-09-12 Invisible Sentinel, Inc. Methods And Compositions For Detecting Multiple Analytes With A Single Signal
US10060910B2 (en) 2012-07-24 2018-08-28 Enzo Life Sciences, Inc. Multisignal reagents for labeling analytes
US9617607B2 (en) 2013-01-08 2017-04-11 Enzo Biochem, Inc. Diagnosis and treatment of viral diseases
WO2014110127A1 (en) 2013-01-08 2014-07-17 Enzo Biochem, Inc. Diagnosis and treatment of viral diseases
DK2992115T3 (da) 2013-04-30 2020-06-02 California Inst Of Techn Multipleksmærkning af molekyler ved stregkodning med sekventiel hybridisering
EP3754028A1 (de) 2019-06-18 2020-12-23 Apollo Life Sciences GmbH Verfahren zur signalcodierung von analyten in einer probe
EP4168576A2 (de) 2020-06-18 2023-04-26 Resolve BioSciences GmbH Multiplexverfahren zum nachweis verschiedener analyte und verschiedener untergruppen/variationen eines analyts in einer probe
CN117858957A (zh) 2021-08-06 2024-04-09 解析生物科学有限公司 用于检测包括病原体的样品中的分析物的方法
US20240295474A1 (en) 2021-10-25 2024-09-05 Resolve Biosciences Gmbh Method of mounting a biological sample on a surface
WO2024002726A1 (en) 2022-06-30 2024-01-04 Resolve Biosciences Gmbh High resolution multiplex method for detecting at least two targets with a distance of beyond the diffraction limit in a sample

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3755086A (en) 1971-02-09 1973-08-28 Hoffmann La Roche Diagnostic method utilizing synthetic deoxyrilionucleotide oligomer template
US3798131A (en) 1972-04-24 1974-03-19 Pasadena Foundation For Medica Assay for polymeric dna as a method for detecting malignancy
FR2422956A1 (fr) 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
US4302204A (en) 1979-07-02 1981-11-24 The Board Of Trustees Of Leland Stanford Junior University Transfer and detection of nucleic acids
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4358535A (en) * 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
CA1219824A (en) * 1981-04-17 1987-03-31 David C. Ward Modified nucleotides and methods of preparing and using same
US4711955A (en) 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
CA1190838A (en) 1981-07-17 1985-07-23 Cavit Akin Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer
CA1180647A (en) 1981-07-17 1985-01-08 Cavit Akin Light-emitting polynucleotide hybridization diagnostic method
FI63596C (fi) 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
AU1606083A (en) * 1982-05-07 1983-12-02 Paragon Diagnostics Competitive immunofluorescence assay and test kit
US5241060A (en) 1982-06-23 1993-08-31 Enzo Diagnostics, Inc. Base moiety-labeled detectable nucleatide
US5260433A (en) 1982-06-23 1993-11-09 Enzo Diagnostics, Inc. Saccharide specific binding system labeled nucleotides
CA1223831A (en) * 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
US4556643A (en) 1982-07-26 1985-12-03 Agracetus Assay method and probe for polynucleotide sequences
GB8306426D0 (en) 1983-03-09 1983-04-13 Malcolm A D B Detecting polynucleotide sequence

Also Published As

Publication number Publication date
NO165975B (no) 1991-01-28
ES547003A0 (es) 1988-04-16
DE3486478T2 (de) 2001-06-28
US20100273145A1 (en) 2010-10-28
AU583787B2 (en) 1989-05-11
JP2577881B2 (ja) 1997-02-05
ATE197480T1 (de) 2000-11-11
EP0611828A1 (de) 1994-08-24
EP0128332B1 (de) 1995-08-02
DK223384D0 (da) 1984-05-04
DE3486400T2 (de) 1996-01-04
DE3486400D1 (de) 1995-09-07
ES8802261A1 (es) 1988-04-16
ATE125947T1 (de) 1995-08-15
CA1228811A (en) 1987-11-03
EP0128332A1 (de) 1984-12-19
IL71666A (en) 1989-02-28
ES532182A0 (es) 1986-06-01
JPS59220647A (ja) 1984-12-12
AU2767584A (en) 1984-11-08
EP0611828B1 (de) 2000-11-08
US9134302B2 (en) 2015-09-15
DK223384A (da) 1984-11-06
ES8608169A1 (es) 1986-06-01
NO165975C (no) 1991-05-08
IL71666A0 (en) 1984-07-31
NO841581L (no) 1984-11-06

Similar Documents

Publication Publication Date Title
DE3486478D1 (de) Zusammensetzung zur Anwendung in einem Bestimmungsverfahren unter Verwendung von Polynukleotidsequenzen
DE68901285D1 (de) Verfahren zum nachweis von nukleotid-sequenzen.
DE69616243D1 (de) Testvorrichtung mit einem stabilen Kopplungsfarbstoff zur Bestimmung von Analyten
ATE167524T1 (de) Verfahren zum nachweis, identifizieren und quantifizieren von organismen und viren
FI900602A0 (fi) Bestaemning.
ES543660A0 (es) Un metodo para determinar una secuencia particular de poli- nucleotidos en un medio de ensayo que contiene acidos nu- cleicos monocatenarios
DK0407789T3 (da) Fremgangsmåde til detektering af nukleinsyrer
ATE107965T1 (de) System zum detektierung von ons.
ATE76507T1 (de) Verfahren zur bestimmung von endotoxin.
ATE80665T1 (de) Verfahren und reagens zur bestimmung von ld-1isoenzym.
DE69331443D1 (de) Verfahren zur bestimmung von nukleinsäuren
DE3853120D1 (de) Schnelles Verfahren zur Identifizierung einer spezifischen Sequenz von Nukleinsäure.
EP0625573A4 (de) Neue dna, durch diese kodiertes polypeptid und methode ihrer beider detektion.
EP0355655A3 (de) Chlorid-Bestimmung
DE3668067D1 (de) Reagens zur feststellung von antigen-antikoerper-reaktionen.
ATE98701T1 (de) Verfahren zur durchfuehrung von hybridisierungstests von nukleinsaeuren.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition