DE3462035D1 - Process for the preparation of 4-quinolinones - Google Patents
Process for the preparation of 4-quinolinonesInfo
- Publication number
- DE3462035D1 DE3462035D1 DE8484401861T DE3462035T DE3462035D1 DE 3462035 D1 DE3462035 D1 DE 3462035D1 DE 8484401861 T DE8484401861 T DE 8484401861T DE 3462035 T DE3462035 T DE 3462035T DE 3462035 D1 DE3462035 D1 DE 3462035D1
- Authority
- DE
- Germany
- Prior art keywords
- formula
- carbon atoms
- phosgene
- denotes
- image
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HETSDWRDICBRSQ-UHFFFAOYSA-N 3h-quinolin-4-one Chemical class C1=CC=C2C(=O)CC=NC2=C1 HETSDWRDICBRSQ-UHFFFAOYSA-N 0.000 title 1
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- BUWPZNOVIHAWHW-UHFFFAOYSA-N 2,3-dihydro-1h-quinolin-4-one Chemical compound C1=CC=C2C(=O)CCNC2=C1 BUWPZNOVIHAWHW-UHFFFAOYSA-N 0.000 abstract 2
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- AQKKRXMVSOXABZ-UHFFFAOYSA-N 3-anilinopropanoic acid Chemical compound OC(=O)CCNC1=CC=CC=C1 AQKKRXMVSOXABZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002841 Lewis acid Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000007517 lewis acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8315073A FR2552430B1 (fr) | 1983-09-22 | 1983-09-22 | Procede de preparation de quinolinones-4 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3462035D1 true DE3462035D1 (en) | 1987-02-19 |
Family
ID=9292446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8484401861T Expired DE3462035D1 (en) | 1983-09-22 | 1984-09-20 | Process for the preparation of 4-quinolinones |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4593101A (de) |
| EP (1) | EP0140748B1 (de) |
| JP (1) | JPS6087267A (de) |
| KR (1) | KR910003365B1 (de) |
| AT (1) | ATE24899T1 (de) |
| DE (1) | DE3462035D1 (de) |
| DK (1) | DK452684A (de) |
| ES (1) | ES536140A0 (de) |
| FR (1) | FR2552430B1 (de) |
| HU (1) | HU192584B (de) |
| IN (1) | IN162623B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20080106928A (ko) * | 2006-02-16 | 2008-12-09 | 더 맥클린 하스피털 코퍼레이션 | 파킨슨병의 치료를 위한 방법들 및 조성물들 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4013662A (en) * | 1974-12-19 | 1977-03-22 | Pfizer Inc. | Alkyl and benzyl 6,7-dialkoxy-2-methyl-4-oxo-1,2,3,4-tetrahydroquinoline-1-carboxylates |
| JPS51139626A (en) * | 1975-05-29 | 1976-12-02 | Sumitomo Chem Co Ltd | A herbicide and a process for its preparation |
| GB2092130B (en) * | 1980-07-28 | 1984-05-10 | Hodogaya Chemical Co Ltd | 4-oximino-1,2,3,4-tetrahydroquinoline derivatives |
| FR2498184A1 (fr) * | 1981-01-16 | 1982-07-23 | Rhone Poulenc Sante | Procede de preparation de quinolinones-4 |
-
1983
- 1983-09-22 FR FR8315073A patent/FR2552430B1/fr not_active Expired
-
1984
- 1984-09-20 JP JP59195864A patent/JPS6087267A/ja active Pending
- 1984-09-20 AT AT84401861T patent/ATE24899T1/de active
- 1984-09-20 KR KR1019840005764A patent/KR910003365B1/ko not_active IP Right Cessation
- 1984-09-20 US US06/652,527 patent/US4593101A/en not_active Expired - Fee Related
- 1984-09-20 EP EP84401861A patent/EP0140748B1/de not_active Expired
- 1984-09-20 DE DE8484401861T patent/DE3462035D1/de not_active Expired
- 1984-09-20 IN IN739/DEL/84A patent/IN162623B/en unknown
- 1984-09-21 HU HU843578A patent/HU192584B/hu unknown
- 1984-09-21 DK DK452684A patent/DK452684A/da not_active Application Discontinuation
- 1984-09-21 ES ES536140A patent/ES536140A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DK452684A (da) | 1985-03-23 |
| IN162623B (de) | 1988-06-18 |
| KR910003365B1 (ko) | 1991-05-28 |
| FR2552430A1 (fr) | 1985-03-29 |
| EP0140748A1 (de) | 1985-05-08 |
| ES8505657A1 (es) | 1985-06-01 |
| HUT36094A (en) | 1985-08-28 |
| KR850002254A (ko) | 1985-05-10 |
| ES536140A0 (es) | 1985-06-01 |
| FR2552430B1 (fr) | 1985-10-25 |
| DK452684D0 (da) | 1984-09-21 |
| ATE24899T1 (de) | 1987-01-15 |
| JPS6087267A (ja) | 1985-05-16 |
| HU192584B (en) | 1987-06-29 |
| US4593101A (en) | 1986-06-03 |
| EP0140748B1 (de) | 1987-01-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |