DE3442568A1 - Verfahren zum kontinuierlichen und automatischen identifizieren, sortieren und zaehlen von teilchen kleiner abmessungen - Google Patents
Verfahren zum kontinuierlichen und automatischen identifizieren, sortieren und zaehlen von teilchen kleiner abmessungenInfo
- Publication number
- DE3442568A1 DE3442568A1 DE19843442568 DE3442568A DE3442568A1 DE 3442568 A1 DE3442568 A1 DE 3442568A1 DE 19843442568 DE19843442568 DE 19843442568 DE 3442568 A DE3442568 A DE 3442568A DE 3442568 A1 DE3442568 A1 DE 3442568A1
- Authority
- DE
- Germany
- Prior art keywords
- continuous
- sample
- sorting
- analysis
- microscope
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 title claims description 41
- 239000002245 particle Substances 0.000 title claims description 8
- 238000004458 analytical method Methods 0.000 claims description 11
- 244000045947 parasite Species 0.000 claims description 9
- 241000894006 Bacteria Species 0.000 claims description 6
- 210000004369 blood Anatomy 0.000 claims description 6
- 239000008280 blood Substances 0.000 claims description 6
- 238000010186 staining Methods 0.000 claims description 6
- DPKHZNPWBDQZCN-UHFFFAOYSA-N acridine orange free base Chemical compound C1=CC(N(C)C)=CC2=NC3=CC(N(C)C)=CC=C3C=C21 DPKHZNPWBDQZCN-UHFFFAOYSA-N 0.000 claims description 5
- DZBUGLKDJFMEHC-UHFFFAOYSA-N benzoquinolinylidene Natural products C1=CC=CC2=CC3=CC=CC=C3N=C21 DZBUGLKDJFMEHC-UHFFFAOYSA-N 0.000 claims description 5
- 238000007664 blowing Methods 0.000 claims description 3
- 201000004792 malaria Diseases 0.000 claims description 3
- 239000008267 milk Substances 0.000 claims description 3
- 210000004080 milk Anatomy 0.000 claims description 3
- 235000013336 milk Nutrition 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 3
- 210000002966 serum Anatomy 0.000 claims description 3
- 238000005507 spraying Methods 0.000 claims description 3
- 239000011521 glass Substances 0.000 claims description 2
- 238000003909 pattern recognition Methods 0.000 claims description 2
- 238000005406 washing Methods 0.000 claims description 2
- 241001657081 Karos Species 0.000 claims 1
- 210000004027 cell Anatomy 0.000 description 7
- 102000053602 DNA Human genes 0.000 description 6
- 108020004414 DNA Proteins 0.000 description 6
- 244000052616 bacterial pathogen Species 0.000 description 4
- 238000011282 treatment Methods 0.000 description 4
- 238000004159 blood analysis Methods 0.000 description 3
- 238000011161 development Methods 0.000 description 3
- 230000018109 developmental process Effects 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 241000193403 Clostridium Species 0.000 description 2
- 210000001789 adipocyte Anatomy 0.000 description 2
- 239000003086 colorant Substances 0.000 description 2
- 238000004040 coloring Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000010166 immunofluorescence Methods 0.000 description 2
- 210000000265 leukocyte Anatomy 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
- 241000589540 Pseudomonas fluorescens Species 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 238000004043 dyeing Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000007429 general method Methods 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 238000010191 image analysis Methods 0.000 description 1
- 239000010842 industrial wastewater Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000009281 ultraviolet germicidal irradiation Methods 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
- G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/60—Type of objects
- G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Theoretical Computer Science (AREA)
- Multimedia (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Image Processing (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8318936A FR2555754A1 (fr) | 1983-11-28 | 1983-11-28 | Procede et dispositif d'analyse automatique d'echantillons biologiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3442568A1 true DE3442568A1 (de) | 1985-06-05 |
Family
ID=9294589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19843442568 Withdrawn DE3442568A1 (de) | 1983-11-28 | 1984-11-22 | Verfahren zum kontinuierlichen und automatischen identifizieren, sortieren und zaehlen von teilchen kleiner abmessungen |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS60133897A (fi) |
| KR (1) | KR850004792A (fi) |
| AU (1) | AU3590384A (fi) |
| BE (1) | BE901099A (fi) |
| BR (1) | BR8406026A (fi) |
| CH (1) | CH661357A5 (fi) |
| DD (1) | DD229218A5 (fi) |
| DE (1) | DE3442568A1 (fi) |
| DK (1) | DK561784A (fi) |
| ES (1) | ES538048A0 (fi) |
| FI (1) | FI844662L (fi) |
| FR (1) | FR2555754A1 (fi) |
| GB (1) | GB2152660A (fi) |
| IL (1) | IL73591A0 (fi) |
| IT (1) | IT1177346B (fi) |
| LU (1) | LU85632A1 (fi) |
| MA (1) | MA20282A1 (fi) |
| NL (1) | NL8403625A (fi) |
| NO (1) | NO844701L (fi) |
| OA (1) | OA07875A (fi) |
| PT (1) | PT79559B (fi) |
| SE (1) | SE8405964L (fi) |
| ZA (1) | ZA849212B (fi) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3705876A1 (de) * | 1986-10-07 | 1988-04-14 | Toa Medical Electronics | Verfahren und vorrichtung fuer fliesscytometrie |
| DE4211904A1 (de) * | 1991-04-09 | 1992-11-19 | Werner Maier | Verfahren und vorrichtung zum erstellen einer artenliste fuer eine fluessige probe |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4918739A (en) * | 1988-08-12 | 1990-04-17 | Maraven, S.A. | Process and system for digital analysis of images applied to stratigraphic data |
| US5130559A (en) * | 1989-08-26 | 1992-07-14 | Trutzschler Gmbh & Co. Kg | Method and apparatus for recognizing particle impurities in textile fiber |
| EP0464276A1 (en) * | 1990-07-02 | 1992-01-08 | International Business Machines Corporation | Computer modelling system |
| GB2254414A (en) * | 1991-03-21 | 1992-10-07 | Univ London | Volume measurement of microbial organisms. |
| US6731100B1 (en) | 1997-05-05 | 2004-05-04 | Chemometec A/S | Method and a system for determination of somatic cells in milk |
| JP2001526780A (ja) | 1997-05-05 | 2001-12-18 | シェモメテック・アクティーゼルスカブ | 液体試料中の粒子の測定の方法およびシステム |
| SE524587C2 (sv) | 2003-02-18 | 2004-08-31 | Delaval Holding Ab | Förfarande och anordning för att räkna somatiska celler eller små fettdroppar i mjölk |
| SE528697C2 (sv) | 2005-03-11 | 2007-01-30 | Hemocue Ab | Volymetrisk bestämning av antalet vita blodkroppar i ett blodprov |
| EP1748030B1 (en) * | 2005-07-07 | 2016-04-20 | Fei Company | Method and apparatus for statistical characterization of nano-particles |
| CN109598328B (zh) * | 2018-11-21 | 2023-09-12 | 山东农业大学 | 一种散布式千粒计数方法、系统、装置及终端 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1389553A (en) * | 1972-05-23 | 1975-04-03 | Legorreta G | Apparatus for investigating microscopic particles |
| GB1404628A (en) * | 1972-12-07 | 1975-09-03 | Coulter Electronics | Method and apparatus for analyzing microscopic particles |
| US4075462A (en) * | 1975-01-08 | 1978-02-21 | William Guy Rowe | Particle analyzer apparatus employing light-sensitive electronic detector array |
| US4122518A (en) * | 1976-05-17 | 1978-10-24 | The United States Of America As Represented By The Administrator Of The National Aeronautics & Space Administration | Automated clinical system for chromosome analysis |
| US4197088A (en) * | 1977-09-23 | 1980-04-08 | Akro-Medic Engineering, Inc. | Method for qualitative and quantitative determination of immunological reactions |
| DE2903625A1 (de) * | 1978-02-03 | 1979-08-09 | Rush Presbyterian St Luke | Vorrichtung zur automatischen blutanalyse |
| JPS58154064A (ja) * | 1982-03-08 | 1983-09-13 | Mitsubishi Rayon Co Ltd | リンパ球ｔ細胞百分率測定方法 |
-
1983
- 1983-11-28 FR FR8318936A patent/FR2555754A1/fr not_active Withdrawn
-
1984
- 1984-11-07 LU LU85632A patent/LU85632A1/fr unknown
- 1984-11-20 BE BE6/48032A patent/BE901099A/fr not_active IP Right Cessation
- 1984-11-22 IL IL73591A patent/IL73591A0/xx unknown
- 1984-11-22 DE DE19843442568 patent/DE3442568A1/de not_active Withdrawn
- 1984-11-26 ZA ZA849212A patent/ZA849212B/xx unknown
- 1984-11-26 DD DD84269894A patent/DD229218A5/de unknown
- 1984-11-27 JP JP59250377A patent/JPS60133897A/ja active Pending
- 1984-11-27 AU AU35903/84A patent/AU3590384A/en not_active Abandoned
- 1984-11-27 NO NO844701A patent/NO844701L/no unknown
- 1984-11-27 SE SE8405964A patent/SE8405964L/ not_active Application Discontinuation
- 1984-11-27 DK DK561784A patent/DK561784A/da not_active Application Discontinuation
- 1984-11-27 OA OA58452A patent/OA07875A/xx unknown
- 1984-11-27 BR BR8406026A patent/BR8406026A/pt unknown
- 1984-11-27 PT PT79559A patent/PT79559B/pt unknown
- 1984-11-28 NL NL8403625A patent/NL8403625A/nl not_active Application Discontinuation
- 1984-11-28 IT IT23769/84A patent/IT1177346B/it active
- 1984-11-28 MA MA20506A patent/MA20282A1/fr unknown
- 1984-11-28 FI FI844662A patent/FI844662L/fi not_active Application Discontinuation
- 1984-11-28 GB GB08429976A patent/GB2152660A/en not_active Withdrawn
- 1984-11-28 ES ES538048A patent/ES538048A0/es active Granted
- 1984-11-28 CH CH5667/84A patent/CH661357A5/fr not_active IP Right Cessation
- 1984-11-28 KR KR1019840007444A patent/KR850004792A/ko not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3705876A1 (de) * | 1986-10-07 | 1988-04-14 | Toa Medical Electronics | Verfahren und vorrichtung fuer fliesscytometrie |
| DE4211904A1 (de) * | 1991-04-09 | 1992-11-19 | Werner Maier | Verfahren und vorrichtung zum erstellen einer artenliste fuer eine fluessige probe |
Also Published As
| Publication number | Publication date |
|---|---|
| SE8405964L (sv) | 1985-05-29 |
| FI844662L (fi) | 1985-05-29 |
| IT8423769A1 (it) | 1986-05-28 |
| GB2152660A (en) | 1985-08-07 |
| DK561784D0 (da) | 1984-11-27 |
| IL73591A0 (en) | 1985-02-28 |
| ES8603994A1 (es) | 1986-01-01 |
| LU85632A1 (fr) | 1985-06-04 |
| OA07875A (fr) | 1986-11-20 |
| DK561784A (da) | 1985-05-29 |
| FR2555754A1 (fr) | 1985-05-31 |
| ES538048A0 (es) | 1986-01-01 |
| DD229218A5 (de) | 1985-10-30 |
| CH661357A5 (fr) | 1987-07-15 |
| GB8429976D0 (en) | 1985-01-09 |
| PT79559A (fr) | 1984-12-01 |
| IT1177346B (it) | 1987-08-26 |
| NL8403625A (nl) | 1985-06-17 |
| MA20282A1 (fr) | 1985-07-01 |
| SE8405964D0 (sv) | 1984-11-27 |
| BR8406026A (pt) | 1985-08-27 |
| JPS60133897A (ja) | 1985-07-17 |
| PT79559B (fr) | 1986-09-08 |
| KR850004792A (ko) | 1985-07-27 |
| AU3590384A (en) | 1985-06-06 |
| NO844701L (no) | 1985-05-29 |
| ZA849212B (en) | 1985-07-31 |
| IT8423769A0 (it) | 1984-11-28 |
| BE901099A (fr) | 1985-03-15 |
| FI844662A0 (fi) | 1984-11-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8139 | Disposal/non-payment of the annual fee |