DE3369975D1 - Threo-adrenalinecarboxylic acid, processes for the production thereof, and pharmaceutical compositions thereof - Google Patents

Threo-adrenalinecarboxylic acid, processes for the production thereof, and pharmaceutical compositions thereof

Info

Publication number
DE3369975D1
DE3369975D1 DE8383304804T DE3369975T DE3369975D1 DE 3369975 D1 DE3369975 D1 DE 3369975D1 DE 8383304804 T DE8383304804 T DE 8383304804T DE 3369975 T DE3369975 T DE 3369975T DE 3369975 D1 DE3369975 D1 DE 3369975D1
Authority
DE
Germany
Prior art keywords
threo
protected
dihydroxyphenyl
serine
resultant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383304804T
Other languages
German (de)
English (en)
Inventor
Hamo Umezawa
Toshiharu Nagatsu
Hirotaro Narabayashi
Tomio Takeuchi
Shuichi Iwadare
Ikuo Matsumoto
Junji Yoshizawa
Hajime Morishima
Koji Tomimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Application granted granted Critical
Publication of DE3369975D1 publication Critical patent/DE3369975D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8383304804T 1982-12-20 1983-08-19 Threo-adrenalinecarboxylic acid, processes for the production thereof, and pharmaceutical compositions thereof Expired DE3369975D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57221797A JPS59112949A (ja) 1982-12-20 1982-12-20 新規なｌ−スレオ−アドレナリン酸

Publications (1)

Publication Number Publication Date
DE3369975D1 true DE3369975D1 (en) 1987-04-09

Family

ID=16772344

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383304804T Expired DE3369975D1 (en) 1982-12-20 1983-08-19 Threo-adrenalinecarboxylic acid, processes for the production thereof, and pharmaceutical compositions thereof

Country Status (6)

Country Link
US (1) US4833268A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0112606B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS59112949A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE25669T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1251220A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3369975D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61145148A (ja) * 1984-12-19 1986-07-02 Sumitomo Seiyaku Kk フエニルセリン誘導体
JPH0788334B2 (ja) * 1985-09-30 1995-09-27 財団法人微生物化学研究会 Ｎ−メチルフエニルセリン誘導体
EP3168208A1 (en) 2015-11-11 2017-05-17 Quimica Sintetica, S.A. Processes for the preparation of diastereomerically and enantiomerically enriched oxazolines
EP3587393B1 (en) 2018-06-21 2024-01-17 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Enzymatic process for the preparation of droxidopa
CN113773214A (zh) * 2021-10-09 2021-12-10 上海吉奉生物科技有限公司 一种n-甲基-d-苏氨酸的合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2868818A (en) * 1953-12-15 1959-01-13 Merck & Co Inc Alpha methyl phenylalanines
CH395129A (de) * 1961-04-13 1965-07-15 Hoffmann La Roche Verfahren zur Herstellung von Methylaminocarbonsäuren
CH562199A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1970-10-30 1975-05-30 Hoffmann La Roche
CH580059A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1973-08-22 1976-09-30 Hoffmann La Roche
US3920728A (en) * 1973-08-22 1975-11-18 Hoffmann La Roche Separation and resolution of isomeric forms of 3-(3,4-dihydroxy-phenyl)-serine
US3891696A (en) * 1973-11-02 1975-06-24 Interx Research Corp Novel, transient pro-drug forms of l-dopa
JPS5419931A (en) * 1977-07-11 1979-02-15 Sumitomo Chem Co Ltd Separation of threo, erythro-3-(3,4-dibenzyloxyphenyl)serines
JPS5629551A (en) * 1979-08-20 1981-03-24 Sumitomo Chem Co Ltd Preparation of optically active threo-3- 3,4- dihydroxyphenyl serine
DE3035026A1 (de) * 1980-09-17 1982-04-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von calciumcarbid
JPH027306A (ja) * 1988-06-27 1990-01-11 Toshiaki Kabe 超伝導性線材

Also Published As

Publication number Publication date
JPS59112949A (ja) 1984-06-29
ATE25669T1 (de) 1987-03-15
JPH0341459B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1991-06-24
EP0112606B1 (en) 1987-03-04
EP0112606A1 (en) 1984-07-04
US4833268A (en) 1989-05-23
CA1251220A (en) 1989-03-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8330 Complete renunciation