DE3363830D1 - Vasotocin derivatives - Google Patents

Vasotocin derivatives

Info

Publication number
DE3363830D1
DE3363830D1 DE8383850335T DE3363830T DE3363830D1 DE 3363830 D1 DE3363830 D1 DE 3363830D1 DE 8383850335 T DE8383850335 T DE 8383850335T DE 3363830 T DE3363830 T DE 3363830T DE 3363830 D1 DE3363830 D1 DE 3363830D1
Authority
DE
Germany
Prior art keywords
peptide residue
sub
derivatives
vasotocin
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383850335T
Other languages
English (en)
Inventor
Per Olof Ragnar Melin
Jerzy Andrzej Trojnar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferring AB
Original Assignee
Ferring AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE8207277A external-priority patent/SE8207277L/xx
Application filed by Ferring AB filed Critical Ferring AB
Application granted granted Critical
Publication of DE3363830D1 publication Critical patent/DE3363830D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/16—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/15—Oxytocin or vasopressin; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE8383850335T 1982-12-21 1983-12-15 Vasotocin derivatives Expired DE3363830D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8207277A SE8207277L (sv) 1982-12-21 1982-12-21 Vasotocin-derivat
SE8302505A SE8302505L (sv) 1982-12-21 1983-05-03 Vasotocin-derivat

Publications (1)

Publication Number Publication Date
DE3363830D1 true DE3363830D1 (en) 1986-07-03

Family

ID=26658329

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8383850335T Expired DE3363830D1 (en) 1982-12-21 1983-12-15 Vasotocin derivatives
DE2000175020 Active DE10075020I2 (de) 1982-12-21 1983-12-15 Vasotocinderivate

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE2000175020 Active DE10075020I2 (de) 1982-12-21 1983-12-15 Vasotocinderivate

Country Status (12)

Country Link
US (1) US4504469A (de)
EP (1) EP0112809B1 (de)
AT (1) ATE20072T1 (de)
AU (1) AU564255B2 (de)
CA (1) CA1216843A (de)
DE (2) DE3363830D1 (de)
DK (1) DK163186C (de)
ES (1) ES8607990A1 (de)
FI (1) FI78305C (de)
IL (1) IL70498A (de)
NL (1) NL300012I2 (de)
NO (1) NO160144C (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599324A (en) * 1984-11-21 1986-07-08 Smithkline Beckman Corporation V1-vasopressin antagonists
US4711877A (en) * 1985-09-18 1987-12-08 Smithkline Beckman Corporation 6-pen-vasopressin compounds
FR2597483B1 (fr) * 1986-04-18 1993-09-10 Flork Michel Nouveaux peptides diuretiques et natriuretiques.
US5055448A (en) * 1987-06-25 1991-10-08 Medical College Of Ohio Linear derivatives of arginine vasopressin antagonists
AT398766B (de) * 1988-05-26 1995-01-25 Gebro Broschek Gmbh Verfahren zur intramolekularen oxidation von zwei -sh gruppen in einer peptidverbindung zu einer disulfidbrücke
CA2014590C (en) * 1989-04-15 1999-12-14 Mitsuo Masaki Novel peptides, and antidementia agents containing the same
US5225528A (en) * 1990-02-27 1993-07-06 Merck & Co., Inc. Cyclic hexapeptide oxytocin antagonists
SE9002384D0 (sv) * 1990-07-09 1990-07-09 Ferring Ab Derivat av baklobshormoner
US20040152170A1 (en) * 2001-12-14 2004-08-05 Lee Chichang Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media
EP1490481A4 (de) * 2001-12-14 2005-12-07 Centocor Inc Zur herstellung von proteinen in chemisch definierten medien geeignete klonale myelomzellinien
US20030166147A1 (en) * 2001-12-14 2003-09-04 Lee Chichang Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media
EP1555029A1 (de) 2004-01-19 2005-07-20 Ferring B.V. Verwendung von Substanzen mit Oxytocinwirkung zur Herstellung eines Arzneimittels zur Behandlung von Bluthochdruck
US8030446B2 (en) * 2006-02-10 2011-10-04 Trustees Of Dartmouth College Mutant proline-and-arginine rich peptides and methods for using the same
CN101357937B (zh) * 2007-07-31 2012-11-07 上海苏豪逸明制药有限公司 固相多肽合成阿托西般的制备方法
CN102127146B (zh) * 2010-12-24 2013-04-24 深圳翰宇药业股份有限公司 一种制备醋酸阿托西班的方法
CN102584953B (zh) * 2012-02-09 2014-01-01 深圳翰宇药业股份有限公司 一种阿托西班的纯化方法
KR20180099708A (ko) 2016-01-04 2018-09-05 메르크 세로노 에스. 에이. 하이드록시프로필티아졸리딘 카르복사미드 유도체의 알파-아미노 에스테르 및 이의 염 형태, 결정 다형체
ES2898778T3 (es) 2016-07-21 2022-03-08 ObsEva SA Pautas posológicas de antagonistas de oxitocina para promover la implantación de embriones y prevenir aborto espontáneo
CA3149898A1 (en) 2019-09-03 2021-03-11 Ernest Loumaye Oxytocin antagonist dosing regimens for promoting embryo implantation and preventing miscarriage
CN115380122A (zh) 2020-02-10 2022-11-22 奥布赛瓦股份公司 用于催产素受体拮抗剂疗法的生物标志物
CN116723838A (zh) 2020-11-16 2023-09-08 艾克索玛(美国)有限责任公司 用于治疗或预防早产的组合物和方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1051686A (de) * 1963-04-05
NL129421C (de) * 1963-08-30 1900-01-01
CH442342A (de) * 1964-07-17 1967-08-31 Sandoz Ag Verfahren zur Herstellung eines neuen Polypeptids
CH495957A (de) * 1966-09-15 1970-09-15 Ceskoslovenska Akademie Ved Verfahren zur Herstellung eines antidiuretisch wirksamen Polypeptids
ZA733419B (en) * 1972-07-04 1974-03-27 Hoffmann La Roche Nonapeptides and process for the preparation thereof
US4081533A (en) * 1976-09-01 1978-03-28 Regents Of The University Of California Method of reducing mammalian fertility and drugs therefor
US4163011A (en) * 1978-08-28 1979-07-31 Orts Richard J Peptide compounds and compositions
SE430885B (sv) * 1980-03-24 1983-12-19 Ferring Ab Oxytocin-derivat
US4367225A (en) * 1981-03-24 1983-01-04 The Medical College Of Ohio Novel antagonists of the antidiuretic and/or vasopressor action of arginine vasopressin

Also Published As

Publication number Publication date
ES8607990A1 (es) 1986-06-01
NL300012I1 (nl) 2000-10-02
FI78305B (fi) 1989-03-31
AU564255B2 (en) 1987-08-06
IL70498A0 (en) 1984-03-30
DK586783A (da) 1984-06-22
ATE20072T1 (de) 1986-06-15
AU2257783A (en) 1984-06-28
DK163186B (da) 1992-02-03
DK163186C (da) 1992-06-22
NO834691L (no) 1984-06-22
DE10075020I1 (de) 2000-09-21
DE10075020I2 (de) 2003-01-09
FI834634A0 (fi) 1983-12-16
ES528211A0 (es) 1986-06-01
EP0112809B1 (de) 1986-05-28
DK586783D0 (da) 1983-12-20
IL70498A (en) 1987-09-16
EP0112809A1 (de) 1984-07-04
US4504469A (en) 1985-03-12
NO160144B (no) 1988-12-05
FI834634A (fi) 1984-06-22
NL300012I2 (nl) 2001-02-01
CA1216843A (en) 1987-01-20
NO160144C (no) 1989-03-15
FI78305C (fi) 1989-07-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: BLUMBACH, KRAMER & PARTNER, 65193 WIESBADEN

V448 Application of spc

Free format text: PRODUCT NAME: ATOSIBAN; REGISTRATION NO/DATE: EU/1/99/124/001, EU/1/99/124/002; 20000120

Spc suppl protection certif: 100 75 020

Filing date: 20000713

V457 Spc granted

Free format text: PRODUCT NAME: ATOSIBAN; REGISTRATION NO/DATE: EU/1/99/124/001, EU/1/99/124/002; 20000120

Spc suppl protection certif: 100 75 020

Filing date: 20000713

V464 Spc expired

Free format text: PRODUCT NAME: ATOSIBAN; REGISTRATION NO/DATE: EU/1/99/124/001, EU/1/99/124/002; 20000120

Spc suppl protection certif: 100 75 020

Filing date: 20000713