DE3363312D1 - Process for preparing (3s)-3-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)-acetyl)amino)-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives - Google Patents
Process for preparing (3s)-3-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)-acetyl)amino)-2-oxo-1-azetidinesulfonic acid and 4-substituted derivativesInfo
- Publication number
- DE3363312D1 DE3363312D1 DE8383300191T DE3363312T DE3363312D1 DE 3363312 D1 DE3363312 D1 DE 3363312D1 DE 8383300191 T DE8383300191 T DE 8383300191T DE 3363312 T DE3363312 T DE 3363312T DE 3363312 D1 DE3363312 D1 DE 3363312D1
- Authority
- DE
- Germany
- Prior art keywords
- amino
- compound
- preparing
- formula
- image
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/344,895 US4443374A (en) | 1982-02-01 | 1982-02-01 | Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]-acetyl]amino]-2-oxo-1-azetidinesulfonic acid, and 4-substituted derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3363312D1 true DE3363312D1 (en) | 1986-06-12 |
Family
ID=23352540
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8383300191T Expired DE3363312D1 (en) | 1982-02-01 | 1983-01-14 | Process for preparing (3s)-3-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)-acetyl)amino)-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives |
Country Status (7)
Country | Link |
---|---|
US (1) | US4443374A (de) |
EP (1) | EP0086556B1 (de) |
JP (1) | JPS58134090A (de) |
AT (1) | ATE19631T1 (de) |
CA (1) | CA1196335A (de) |
DE (1) | DE3363312D1 (de) |
IE (1) | IE54430B1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58210061A (ja) * | 1982-05-31 | 1983-12-07 | Takeda Chem Ind Ltd | 1−スルホ−2−オキソアゼチジン誘導体、その製造法および用途 |
US4704457A (en) * | 1982-06-21 | 1987-11-03 | E. R. Squibb & Sons, Inc. | Process for the preparation of (3S)-3-[[[2-(protected amino)-4-thiazolyl]-oxoacetyl]amino]-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives thereof |
US4596777A (en) * | 1983-08-10 | 1986-06-24 | E. R. Squibb & Sons, Inc. | Process for preparing (3S)-3-[[[2-(protected or unprotected amino)-4-thiazolyl]acetyl]amino]-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives thereof |
AT381944B (de) * | 1984-04-10 | 1986-12-10 | Biochemie Gmbh | Verfahren zur herstellung von cephalosporinantibiotika |
US4675398A (en) * | 1985-08-16 | 1987-06-23 | E. R. Squibb & Sons, Inc. | Copper-mediated oximation reaction |
US4684722A (en) * | 1986-01-06 | 1987-08-04 | E. R. Squibb & Sons, Inc. | Monosulfactams |
KR100472048B1 (ko) * | 2002-07-11 | 2005-03-08 | 종근당바이오 주식회사 | 아즈트레오남의 신규제조방법 |
JP2008505189A (ja) * | 2005-05-09 | 2008-02-21 | シコール インコーポレイティド | アズトレオナムの製造方法 |
CN103570707B (zh) * | 2012-07-21 | 2016-03-09 | 重庆圣华曦药业股份有限公司 | 一种改进的氨曲南的合成方法 |
US11414411B2 (en) * | 2017-08-02 | 2022-08-16 | Novartis Ag | Chemical process for manufacturing monobactam antibiotic and intermediates thereof |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1389194A (en) * | 1971-01-29 | 1975-04-03 | Glaxo Lab Ltd | Antibiotics |
US4024133A (en) * | 1971-05-14 | 1977-05-17 | Glaxo Laboratories Limited | 7β-[2-Etherified oximino-2-(thienyl-,furyl- or pyridylacetamido)]cephalosporins |
US4191762A (en) * | 1974-03-14 | 1980-03-04 | Fujisawa Pharmaceutical Co., Ltd. | 2-Lower alkyl-7-substituted amino-2 or 3-cephem-4-carboxylic acid compounds |
US4152433A (en) * | 1976-03-12 | 1979-05-01 | Fujisawa Pharmaceutical Co., Ltd. | 2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds and pharmaceutical compositions |
US4166115A (en) * | 1976-04-12 | 1979-08-28 | Fujisawa Pharmaceutical Co., Ltd. | Syn 7-oxoimino substituted derivatives of cephalosporanic acid |
FI771866A (de) * | 1976-06-28 | 1977-12-29 | Fujisawa Pharmaceutical Co | |
DE2710902A1 (de) * | 1977-03-12 | 1978-09-21 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
DE2818263A1 (de) * | 1978-04-26 | 1979-11-08 | Bayer Ag | Beta-lactamantibiotika |
DE2822861A1 (de) * | 1978-05-26 | 1979-11-29 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
US4409214A (en) * | 1979-11-19 | 1983-10-11 | Fujisawa Pharmaceutical, Co., Ltd. | 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof |
NZ205240A (en) * | 1980-02-07 | 1984-07-31 | Squibb & Sons Inc | Sulphonamide derivatives,being starting materials for producing beta-lactams |
FR2515182B1 (fr) * | 1981-10-23 | 1986-05-09 | Roussel Uclaf | Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation |
-
1982
- 1982-02-01 US US06/344,895 patent/US4443374A/en not_active Expired - Lifetime
-
1983
- 1983-01-14 DE DE8383300191T patent/DE3363312D1/de not_active Expired
- 1983-01-14 AT AT83300191T patent/ATE19631T1/de not_active IP Right Cessation
- 1983-01-14 EP EP83300191A patent/EP0086556B1/de not_active Expired
- 1983-01-27 CA CA000420362A patent/CA1196335A/en not_active Expired
- 1983-01-28 IE IE166/83A patent/IE54430B1/en not_active IP Right Cessation
- 1983-01-29 JP JP58013621A patent/JPS58134090A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
IE54430B1 (en) | 1989-10-11 |
EP0086556A1 (de) | 1983-08-24 |
IE830166L (en) | 1983-08-01 |
EP0086556B1 (de) | 1986-05-07 |
JPH0312065B2 (de) | 1991-02-19 |
US4443374A (en) | 1984-04-17 |
CA1196335A (en) | 1985-11-05 |
JPS58134090A (ja) | 1983-08-10 |
ATE19631T1 (de) | 1986-05-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2109482A1 (en) | Process for producing alanylglutamine | |
CA2095587A1 (en) | Process for preparing aryl piperazinyl-hetero-cyclic compounds | |
FI91068C (fi) | Menetelmä diorganodialkoksisilaanien valmistamiseksi | |
DE3363312D1 (en) | Process for preparing (3s)-3-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)-acetyl)amino)-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives | |
DE3472407D1 (en) | Process for preparing cyanohydrine derivatives containing phosphorus | |
IE820554L (en) | Beta-lactams and 1-aza-bicyclo compounds. | |
ES8304971A1 (es) | Un procedimiento para la preparacion de derivados de tiocarbapenem 3-sustituidos. | |
GR3030211T3 (en) | Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate. | |
AU563050B2 (en) | Synthesis of azetidin-3-ols | |
DE3260631D1 (en) | Process for the preparation of hydrazidines | |
ES8404150A1 (es) | Procedimiento para la preparacion de n-pteridinilureas. | |
EP0060301A4 (de) | Verfahren zur herstellung von cephalosporinverbindungen. | |
IL66237A0 (en) | Preparation of hydrazidines | |
DE3469527D1 (en) | Nortropine derivative, process for its preparation and its use | |
AU6451694A (en) | Process for converting loracarbef dihydrate to loracarbef monohydrate | |
DE3269684D1 (en) | Process for preparing (thio)hydantoins | |
JPS6452767A (en) | 2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-vinyloxyimino)acetic acid derivative and production thereof | |
NZ316799A (en) | Process for preparing benzyl-substituted rhodanine derivatives | |
ES447552A1 (es) | Un procedimiento para la preparacion de nuevos derivados delacido cefalosporanico. | |
MX9706606A (es) | Procedimiento para la preparacion del monohidrato de loracarbef. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |