DE3328952A1 - Neue polypeptide, verfahren zu ihrer herstellung, pharmazeutische praeparate welche sie enthalten, sowie ihre verwendung - Google Patents

Neue polypeptide, verfahren zu ihrer herstellung, pharmazeutische praeparate welche sie enthalten, sowie ihre verwendung

Info

Publication number
DE3328952A1
DE3328952A1 DE19833328952 DE3328952A DE3328952A1 DE 3328952 A1 DE3328952 A1 DE 3328952A1 DE 19833328952 DE19833328952 DE 19833328952 DE 3328952 A DE3328952 A DE 3328952A DE 3328952 A1 DE3328952 A1 DE 3328952A1
Authority
DE
Germany
Prior art keywords
carbon atoms
polypeptides
alkyl
hydrogen
free
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19833328952
Other languages
German (de)
English (en)
Inventor
Wilfried 4431 Lampenberg Bauer
Janos Dr. 4054 Basel Pless
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Sandoz Patent GmbH
Original Assignee
Sandoz AG
Sandoz Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG, Sandoz Patent GmbH filed Critical Sandoz AG
Publication of DE3328952A1 publication Critical patent/DE3328952A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE19833328952 1982-08-24 1983-08-11 Neue polypeptide, verfahren zu ihrer herstellung, pharmazeutische praeparate welche sie enthalten, sowie ihre verwendung Withdrawn DE3328952A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH503182A CH655505B (US07176919-20070213-C00032.png) 1982-08-24 1982-08-24

Publications (1)

Publication Number Publication Date
DE3328952A1 true DE3328952A1 (de) 1984-03-01

Family

ID=4286762

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19833328952 Withdrawn DE3328952A1 (de) 1982-08-24 1983-08-11 Neue polypeptide, verfahren zu ihrer herstellung, pharmazeutische praeparate welche sie enthalten, sowie ihre verwendung

Country Status (14)

Country Link
US (1) US4496543A (US07176919-20070213-C00032.png)
JP (1) JPH0615558B2 (US07176919-20070213-C00032.png)
AU (1) AU1833383A (US07176919-20070213-C00032.png)
BE (1) BE897546A (US07176919-20070213-C00032.png)
CH (1) CH655505B (US07176919-20070213-C00032.png)
DE (1) DE3328952A1 (US07176919-20070213-C00032.png)
FR (1) FR2532308B1 (US07176919-20070213-C00032.png)
GB (1) GB2125799B (US07176919-20070213-C00032.png)
IL (1) IL69540A0 (US07176919-20070213-C00032.png)
IT (1) IT1169770B (US07176919-20070213-C00032.png)
NL (1) NL8302935A (US07176919-20070213-C00032.png)
PH (1) PH19787A (US07176919-20070213-C00032.png)
SE (1) SE8304573L (US07176919-20070213-C00032.png)
ZA (1) ZA836276B (US07176919-20070213-C00032.png)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684620A (en) * 1984-09-04 1987-08-04 Gibson-Stephens Neuropharmaceuticals, Inc. Cyclic polypeptides having mu-receptor specificity
US4725577A (en) * 1985-04-25 1988-02-16 Administrators Of The Tulane Educational Fund Biologically active lysine containing octapeptides
US4650787A (en) * 1985-04-25 1987-03-17 Schally Andrew Victor Biologically active octapeptides
JPH085913B2 (ja) * 1985-09-12 1996-01-24 ザ・アドミニストレ−タ−ズ・オブ・ザ・ツ−レイン・エデユケイシヨナル・フアンド 治療用ソマトスタチン同族体
GR862206B (en) * 1985-09-12 1986-12-31 Univ Tulane Therapeutic somatostatin analogs
US4803261A (en) * 1986-06-27 1989-02-07 The Administrators Of The Tulane Educational Fund Method for synthesizing a peptide containing a non-peptide
US5006510A (en) * 1989-06-20 1991-04-09 Ellis Wladislaw V Method for relieving chronic pain with a somatostatin analog composition
JP3227673B2 (ja) * 1992-06-19 2001-11-12 味の素株式会社 膵炎予防治療薬
US6184208B1 (en) 1994-06-29 2001-02-06 Immunotech Developments Inc. Peptide, a method for its preparation and a pharmaceutical composition containing the peptide

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0029579A1 (en) * 1979-11-27 1981-06-03 Sandoz Ag Polypeptides, processes for their production, pharmaceutical compositions comprising said polypeptides and their use
DE3207311A1 (de) * 1981-03-06 1982-12-02 Sandoz-Patent-GmbH, 7850 Lörrach Neue n-acylpolypeptide und ihre herstellung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235886A (en) * 1979-10-31 1980-11-25 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
US4282143A (en) * 1980-06-13 1981-08-04 American Home Products Corporation Octapeptides lowering growth hormone
US4328135A (en) * 1980-06-13 1982-05-04 American Home Products Corporation Octapeptides lowering growth hormone
US4360516A (en) * 1981-04-13 1982-11-23 Merck & Co., Inc. Modified D-retro cyclic hexapeptide somatostatin analogs

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0029579A1 (en) * 1979-11-27 1981-06-03 Sandoz Ag Polypeptides, processes for their production, pharmaceutical compositions comprising said polypeptides and their use
DE3207311A1 (de) * 1981-03-06 1982-12-02 Sandoz-Patent-GmbH, 7850 Lörrach Neue n-acylpolypeptide und ihre herstellung

Also Published As

Publication number Publication date
NL8302935A (nl) 1984-03-16
PH19787A (en) 1986-07-02
FR2532308B1 (fr) 1987-09-11
GB2125799B (en) 1985-09-11
IT1169770B (it) 1987-06-03
JPH0615558B2 (ja) 1994-03-02
ZA836276B (en) 1985-04-24
CH655505B (US07176919-20070213-C00032.png) 1986-04-30
US4496543A (en) 1985-01-29
GB2125799A (en) 1984-03-14
IT8322612A0 (it) 1983-08-23
JPS5962557A (ja) 1984-04-10
SE8304573L (sv) 1984-02-25
IL69540A0 (en) 1983-11-30
GB8322529D0 (en) 1983-09-21
SE8304573D0 (sv) 1983-08-23
FR2532308A1 (fr) 1984-03-02
BE897546A (fr) 1984-02-17
AU1833383A (en) 1984-03-01

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8125 Change of the main classification

Ipc: C07K 14/655

8139 Disposal/non-payment of the annual fee