DE3316155A1 - 2-(2'hydroxy-3'-(1,1-dimethylpropylamino)-propoxy)-1-thienylpropiophenon, seine saeureadditionssalze, verfahren zu seiner herstellung und arzneimittel - Google Patents
2-(2'hydroxy-3'-(1,1-dimethylpropylamino)-propoxy)-1-thienylpropiophenon, seine saeureadditionssalze, verfahren zu seiner herstellung und arzneimittelInfo
- Publication number
- DE3316155A1 DE3316155A1 DE19833316155 DE3316155A DE3316155A1 DE 3316155 A1 DE3316155 A1 DE 3316155A1 DE 19833316155 DE19833316155 DE 19833316155 DE 3316155 A DE3316155 A DE 3316155A DE 3316155 A1 DE3316155 A1 DE 3316155A1
- Authority
- DE
- Germany
- Prior art keywords
- hydroxy
- acid addition
- formula
- acid
- dimethylpropylamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- TVMXDCGIABBOFY-UHFFFAOYSA-N octane Chemical compound CCCCCCCC TVMXDCGIABBOFY-UHFFFAOYSA-N 0.000 description 1
- 239000012074 organic phase Substances 0.000 description 1
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- 229940075930 picrate Drugs 0.000 description 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-M picrate anion Chemical compound [O-]C1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-M 0.000 description 1
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- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
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- 239000004208 shellac Substances 0.000 description 1
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- ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 description 1
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- 239000012312 sodium hydride Substances 0.000 description 1
- 229910000104 sodium hydride Inorganic materials 0.000 description 1
- 235000009518 sodium iodide Nutrition 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833316155 DE3316155A1 (de) | 1983-05-03 | 1983-05-03 | 2-(2'hydroxy-3'-(1,1-dimethylpropylamino)-propoxy)-1-thienylpropiophenon, seine saeureadditionssalze, verfahren zu seiner herstellung und arzneimittel |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833316155 DE3316155A1 (de) | 1983-05-03 | 1983-05-03 | 2-(2'hydroxy-3'-(1,1-dimethylpropylamino)-propoxy)-1-thienylpropiophenon, seine saeureadditionssalze, verfahren zu seiner herstellung und arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3316155A1 true DE3316155A1 (de) | 1984-11-08 |
| DE3316155C2 DE3316155C2 (enrdf_load_stackoverflow) | 1992-11-26 |
Family
ID=6198050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19833316155 Granted DE3316155A1 (de) | 1983-05-03 | 1983-05-03 | 2-(2'hydroxy-3'-(1,1-dimethylpropylamino)-propoxy)-1-thienylpropiophenon, seine saeureadditionssalze, verfahren zu seiner herstellung und arzneimittel |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE3316155A1 (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0266336A1 (de) * | 1986-10-29 | 1988-05-04 | Dieter Prof. Dr. Binder | Neue 1-/ 3-(2-Dialkylaminoäthoxy)-2-thienyl/-3-phenyl-1-propanone und ihre Säureadditionssalze und Verfahren zu deren Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
| EP0381661A1 (de) * | 1989-01-24 | 1990-08-08 | Laevosan-Gesellschaft m.b.H. | 1-E3-(2-Hydroxy-3-alkylaminopropoxy)-2-thienyl]-3-phenyl-1-propanone und Verfahren zu deren Herstellung |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0053603A1 (de) * | 1980-11-28 | 1982-06-09 | Laevosan-Gesellschaft m.b.H. & Co KG | 1-(3-(2-Hydroxy-3-alkylaminopropoxy)-2-thienyl)-3-phenyl-1-propanone und ihre Säureadditionssalze sowie Verfahren zu deren Herstellung |
-
1983
- 1983-05-03 DE DE19833316155 patent/DE3316155A1/de active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0053603A1 (de) * | 1980-11-28 | 1982-06-09 | Laevosan-Gesellschaft m.b.H. & Co KG | 1-(3-(2-Hydroxy-3-alkylaminopropoxy)-2-thienyl)-3-phenyl-1-propanone und ihre Säureadditionssalze sowie Verfahren zu deren Herstellung |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0266336A1 (de) * | 1986-10-29 | 1988-05-04 | Dieter Prof. Dr. Binder | Neue 1-/ 3-(2-Dialkylaminoäthoxy)-2-thienyl/-3-phenyl-1-propanone und ihre Säureadditionssalze und Verfahren zu deren Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
| EP0381661A1 (de) * | 1989-01-24 | 1990-08-08 | Laevosan-Gesellschaft m.b.H. | 1-E3-(2-Hydroxy-3-alkylaminopropoxy)-2-thienyl]-3-phenyl-1-propanone und Verfahren zu deren Herstellung |
| US4994484A (en) * | 1989-01-24 | 1991-02-19 | Laevosan-Gesellschaft M.B.H. | 1-(3-(2-hydroxy-3-alkylaminopropoxy)-2-thienyl)-3-phenyl-1-propanones and process for the preparation of the same |
Also Published As
| Publication number | Publication date |
|---|---|
| DE3316155C2 (enrdf_load_stackoverflow) | 1992-11-26 |
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Legal Events
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| 8127 | New person/name/address of the applicant |
Owner name: HELOPHARM W. PETRIK GMBH & CO KG, 1000 BERLIN, DE |
|
| 8110 | Request for examination paragraph 44 | ||
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |