DE3272892D1 - Substituted pyrimid-2-ones, the salts thereof, processes for their preparation and pharmaceutical compositions containing them - Google Patents

Substituted pyrimid-2-ones, the salts thereof, processes for their preparation and pharmaceutical compositions containing them

Info

Publication number
DE3272892D1
DE3272892D1 DE8282304780T DE3272892T DE3272892D1 DE 3272892 D1 DE3272892 D1 DE 3272892D1 DE 8282304780 T DE8282304780 T DE 8282304780T DE 3272892 T DE3272892 T DE 3272892T DE 3272892 D1 DE3272892 D1 DE 3272892D1
Authority
DE
Germany
Prior art keywords
group
salts
ones
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282304780T
Other languages
English (en)
Inventor
Tore Benneche
Mikkel Josef Gacek
Kjell Undheim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nyegaard and Co AS
Original Assignee
Nyegaard and Co AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nyegaard and Co AS filed Critical Nyegaard and Co AS
Application granted granted Critical
Publication of DE3272892D1 publication Critical patent/DE3272892D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
DE8282304780T 1981-09-11 1982-09-10 Substituted pyrimid-2-ones, the salts thereof, processes for their preparation and pharmaceutical compositions containing them Expired DE3272892D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8127505 1981-09-11

Publications (1)

Publication Number Publication Date
DE3272892D1 true DE3272892D1 (en) 1986-10-02

Family

ID=10524445

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282304780T Expired DE3272892D1 (en) 1981-09-11 1982-09-10 Substituted pyrimid-2-ones, the salts thereof, processes for their preparation and pharmaceutical compositions containing them

Country Status (11)

Country Link
US (1) US4478839A (de)
EP (1) EP0074820B1 (de)
JP (1) JPS5857368A (de)
AT (1) ATE21693T1 (de)
AU (1) AU8818882A (de)
DE (1) DE3272892D1 (de)
DK (1) DK404982A (de)
ES (1) ES8308860A1 (de)
NO (1) NO823075L (de)
NZ (1) NZ201883A (de)
ZA (1) ZA826660B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO161440C (no) * 1982-02-24 1989-08-16 Nyegaard & Co As Analogifremgangsmaate for fremstilling av fysiologisk aktive pyrimidin-2-oner.
JPH0613535B2 (ja) * 1984-09-10 1994-02-23 株式会社三和化学研究所 新規な有機珪素化合物、その製法並びに該化合物を有効成分とする抗腫瘍剤
US4675321A (en) * 1986-02-07 1987-06-23 Merck & Co., Inc. Substituted pyrimidines useful as calcium channel blockers
JP2873340B2 (ja) * 1988-04-29 1999-03-24 武田薬品工業株式会社 抗生物質ｔａｎ―１０５７，その製造法および用途
US8679231B2 (en) 2011-01-19 2014-03-25 Advanced Technology Materials, Inc. PVDF pyrolyzate adsorbent and gas storage and dispensing system utilizing same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1561290A (en) * 1975-10-16 1980-02-20 Nyegaard & Co As Pyrimid - 2 - ones
US4052400A (en) * 1976-10-29 1977-10-04 Morton-Norwich Products, Inc. Hypertensive 1-substituted 2(1h)-pyrimidones

Also Published As

Publication number Publication date
EP0074820B1 (de) 1986-08-27
JPS5857368A (ja) 1983-04-05
ES515640A0 (es) 1983-10-01
NZ201883A (en) 1985-11-08
AU8818882A (en) 1983-03-17
ZA826660B (en) 1983-08-31
ES8308860A1 (es) 1983-10-01
DK404982A (da) 1983-03-12
EP0074820A1 (de) 1983-03-23
ATE21693T1 (de) 1986-09-15
US4478839A (en) 1984-10-23
NO823075L (no) 1983-03-14

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee