DE3262880D1 - Tricyclic ethers, process for their preparation and their use in pharmaceutical preparations - Google Patents

Tricyclic ethers, process for their preparation and their use in pharmaceutical preparations

Info

Publication number
DE3262880D1
DE3262880D1 DE8282401567T DE3262880T DE3262880D1 DE 3262880 D1 DE3262880 D1 DE 3262880D1 DE 8282401567 T DE8282401567 T DE 8282401567T DE 3262880 T DE3262880 T DE 3262880T DE 3262880 D1 DE3262880 D1 DE 3262880D1
Authority
DE
Germany
Prior art keywords
group
lower alkyl
preparation
pharmaceutical preparations
different
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282401567T
Other languages
German (de)
English (en)
Inventor
Charles Malen
Jean-Claude Poignant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of DE3262880D1 publication Critical patent/DE3262880D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12—[b,e]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D267/18—[b, e]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8282401567T 1981-08-27 1982-08-24 Tricyclic ethers, process for their preparation and their use in pharmaceutical preparations Expired DE3262880D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8116347A FR2512024A1 (fr) 1981-08-27 1981-08-27 Ethers tricycliques, leur preparation et les compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
DE3262880D1 true DE3262880D1 (en) 1985-05-09

Family

ID=9261704

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282401567T Expired DE3262880D1 (en) 1981-08-27 1982-08-24 Tricyclic ethers, process for their preparation and their use in pharmaceutical preparations

Country Status (14)

Country Link
US (1) US4496557A (enExample)
EP (1) EP0074304B1 (enExample)
JP (1) JPS5874673A (enExample)
AT (1) ATE12497T1 (enExample)
AU (1) AU8773082A (enExample)
CA (1) CA1227481A (enExample)
DE (1) DE3262880D1 (enExample)
ES (1) ES515232A0 (enExample)
FR (1) FR2512024A1 (enExample)
GR (1) GR77595B (enExample)
IL (1) IL66650A (enExample)
NZ (1) NZ201740A (enExample)
PT (1) PT75471B (enExample)
ZA (1) ZA826252B (enExample)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8500273D0 (sv) * 1985-01-22 1985-01-22 Leo Ab Nya tricykliska foreningar, kompositioner innehallande sadana foreningar, framstellningsforfaranden och behandlingsmetoder
EP0332246A1 (en) * 1988-03-11 1989-09-13 Akzo N.V. Tricyclic amine derivatives
US5180736A (en) * 1989-03-23 1993-01-19 Warner-Lambert Company Polycyclic amines useful as cerebrovascular agents
US5006536A (en) * 1989-12-26 1991-04-09 Hoechst-Roussel Pharmaceuticals Inc. Thienobenzoxepins and analgesic compositions thereof
US5260319A (en) * 1989-12-26 1993-11-09 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
US5574173A (en) * 1993-12-06 1996-11-12 Schering Corporation Tricyclic derivatives, compositions and methods of use
ES2160790T3 (es) * 1995-02-08 2001-11-16 Novartis Ag 10-aminoalifatil-dibenzo(b,f)oxepinas de accion antineurodegenerativa.
US5698551A (en) * 1995-04-07 1997-12-16 Novo Nordisk A/S Heterocyclic compounds
US7577282B2 (en) 2002-11-27 2009-08-18 Hologic, Inc. Image handling and display in X-ray mammography and tomosynthesis
US7123684B2 (en) * 2002-11-27 2006-10-17 Hologic, Inc. Full field mammography with tissue exposure control, tomosynthesis, and dynamic field of view processing
US8571289B2 (en) 2002-11-27 2013-10-29 Hologic, Inc. System and method for generating a 2D image from a tomosynthesis data set
US7616801B2 (en) 2002-11-27 2009-11-10 Hologic, Inc. Image handling and display in x-ray mammography and tomosynthesis
US8565372B2 (en) 2003-11-26 2013-10-22 Hologic, Inc System and method for low dose tomosynthesis
US10638994B2 (en) 2002-11-27 2020-05-05 Hologic, Inc. X-ray mammography with tomosynthesis
US8768026B2 (en) 2003-11-26 2014-07-01 Hologic, Inc. X-ray imaging with x-ray markers that provide adjunct information but preserve image quality
US7662082B2 (en) 2004-11-05 2010-02-16 Theragenics Corporation Expandable brachytherapy device
US7702142B2 (en) * 2004-11-15 2010-04-20 Hologic, Inc. Matching geometry generation and display of mammograms and tomosynthesis images
US7869563B2 (en) * 2004-11-26 2011-01-11 Hologic, Inc. Integrated multi-mode mammography/tomosynthesis x-ray system and method
US7245694B2 (en) 2005-08-15 2007-07-17 Hologic, Inc. X-ray mammography/tomosynthesis of patient's breast
US8079946B2 (en) 2005-11-18 2011-12-20 Senorx, Inc. Asymmetrical irradiation of a body cavity
US8532745B2 (en) 2006-02-15 2013-09-10 Hologic, Inc. Breast biopsy and needle localization using tomosynthesis systems
US7630533B2 (en) 2007-09-20 2009-12-08 Hologic, Inc. Breast tomosynthesis with display of highlighted suspected calcifications
US7991106B2 (en) 2008-08-29 2011-08-02 Hologic, Inc. Multi-mode tomosynthesis/mammography gain calibration and image correction using gain map information from selected projection angles
KR20110063659A (ko) 2008-09-04 2011-06-13 홀로직, 인크. 통합된 다중 모드 마모그래피/토모신테시스 ｘ선 시스템 및 방법
US9579524B2 (en) 2009-02-11 2017-02-28 Hologic, Inc. Flexible multi-lumen brachytherapy device
US9248311B2 (en) 2009-02-11 2016-02-02 Hologic, Inc. System and method for modifying a flexibility of a brachythereapy catheter
US8170320B2 (en) * 2009-03-03 2012-05-01 Hologic, Inc. Mammography/tomosynthesis systems and methods automatically deriving breast characteristics from breast x-ray images and automatically adjusting image processing parameters accordingly
US10207126B2 (en) 2009-05-11 2019-02-19 Cytyc Corporation Lumen visualization and identification system for multi-lumen balloon catheter
US10595954B2 (en) 2009-10-08 2020-03-24 Hologic, Inc. Needle breast biopsy system and method for use
US9352172B2 (en) 2010-09-30 2016-05-31 Hologic, Inc. Using a guide member to facilitate brachytherapy device swap
KR101836549B1 (ko) 2010-10-05 2018-03-08 홀로직, 인크. Ｃｔ 모드, 다중 단층영상합성 모드들, 및 유방조영술 모드를 갖는 직립형 ｘ-레이 유방 촬영
US20120133600A1 (en) 2010-11-26 2012-05-31 Hologic, Inc. User interface for medical image review workstation
US10342992B2 (en) 2011-01-06 2019-07-09 Hologic, Inc. Orienting a brachytherapy applicator
AU2012225398B2 (en) 2011-03-08 2017-02-02 Hologic, Inc. System and method for dual energy and/or contrast enhanced breast imaging for screening, diagnosis and biopsy
US11259759B2 (en) 2011-11-18 2022-03-01 Hologic Inc. X-ray mammography and/or breast tomosynthesis using a compression paddle
JP2014534042A (ja) 2011-11-27 2014-12-18 ホロジック, インコーポレイテッドHologic, Inc. マンモグラフィーおよび／またはトモシンセシス画像データを使用して２ｄ画像を生成するためのシステムおよび方法
US9805507B2 (en) 2012-02-13 2017-10-31 Hologic, Inc System and method for navigating a tomosynthesis stack using synthesized image data
JP6392309B2 (ja) 2013-03-15 2018-09-19 ホロジック インコーポレイティッド 自動合焦を含む、トモシンセシススタックをナビゲートするためのシステム
EP2967479B1 (en) 2013-03-15 2018-01-31 Hologic Inc. Tomosynthesis-guided biopsy in prone
EP3055837B1 (en) 2013-10-09 2021-08-04 Hologic, Inc. X-ray breast tomosynthesis enhancing spatial resolution including in the thickness direction of a flattened breast
CN106170255A (zh) 2013-10-24 2016-11-30 安德鲁·P·史密斯 用于导航x射线引导的乳房活检的系统和方法
JP6506769B2 (ja) 2014-02-28 2019-04-24 ホロジック, インコーポレイテッドHologic, Inc. トモシンセシス画像スラブを生成し表示するためのシステムおよび方法
AU2015343319B2 (en) 2014-11-07 2020-07-23 Hologic, Inc. Pivoting paddle apparatus for mammography/tomosynthesis x-ray system
WO2017185028A1 (en) 2016-04-22 2017-10-26 Hologic, Inc. Tomosynthesis with shifting focal spot x-ray system using an addressable array
CA3040862A1 (en) 2016-11-08 2018-05-17 Hologic, Inc. Imaging with curved compression elements
JP7174710B2 (ja) 2017-03-30 2022-11-17 ホロジック， インコーポレイテッド 合成乳房組織画像を生成するための標的オブジェクト増強のためのシステムおよび方法
EP3600051B1 (en) 2017-03-30 2024-05-01 Hologic, Inc. Method for synthesizing low-dimensional image data from high-dimensional image data using an object grid enhancement
US11399790B2 (en) 2017-03-30 2022-08-02 Hologic, Inc. System and method for hierarchical multi-level feature image synthesis and representation
DE202018006897U1 (de) 2017-06-20 2024-06-03 Hologic Inc. Dynamisches, selbstlernendes System für medizinische Bilder
CN111031920B (zh) 2017-08-11 2024-05-07 豪洛捷公司 具有可膨胀护套的乳房压缩桨板
AU2018313272B2 (en) 2017-08-11 2024-01-11 Hologic, Inc. Breast compression paddle with access corners
DE202018006917U1 (de) 2017-08-16 2024-07-18 Hologic Inc. Techniken zur Patientenbewegungsartefaktkompensation bei Brustbildgebung
EP3449835B1 (en) 2017-08-22 2023-01-11 Hologic, Inc. Computed tomography system and method for imaging multiple anatomical targets
US11090017B2 (en) 2018-09-13 2021-08-17 Hologic, Inc. Generating synthesized projection images for 3D breast tomosynthesis or multi-mode x-ray breast imaging
AU2019349684B2 (en) 2018-09-24 2025-04-10 Hologic, Inc. Breast mapping and abnormality localization
JP7482860B2 (ja) 2018-09-28 2024-05-14 ホロジック， インコーポレイテッド 高密度要素抑制による合成乳房組織画像発生のためのシステムおよび方法
JP7430720B2 (ja) 2018-11-25 2024-02-13 ホロジック， インコーポレイテッド マルチモダリティハンギングプロトコル
KR20210148132A (ko) 2019-03-29 2021-12-07 홀로직, 인크. 스닙-트리거링된 디지털 영상 보고서 생성
EP3832689A3 (en) 2019-12-05 2021-08-11 Hologic, Inc. Systems and methods for improved x-ray tube life
KR20220130759A (ko) 2020-01-24 2022-09-27 홀로직, 인크. 수평-변위 가능 발포체 유방 압축 패들
US11471118B2 (en) 2020-03-27 2022-10-18 Hologic, Inc. System and method for tracking x-ray tube focal spot position
EP4125604B1 (en) 2020-03-27 2026-01-07 Hologic, Inc. Systems and methods for identifying regions of interest in multiple imaging modalities
JP2024514268A (ja) 2021-04-26 2024-03-29 ホロジック， インコーポレイテッド 発泡体圧迫要素の厚さを測定するためのシステムおよび方法
US11786191B2 (en) 2021-05-17 2023-10-17 Hologic, Inc. Contrast-enhanced tomosynthesis with a copper filter
US12186119B2 (en) 2021-10-05 2025-01-07 Hologic, Inc. Interactive model interface for image selection in medical imaging systems
US12254586B2 (en) 2021-10-25 2025-03-18 Hologic, Inc. Auto-focus tool for multimodality image review
CN118318247A (zh) 2021-11-29 2024-07-09 豪洛捷公司 用于将感兴趣的对象相关的系统和方法
US12414217B2 (en) 2022-02-07 2025-09-09 Hologic, Inc. Systems and methods for adaptively controlling filament current in an X-ray tube

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3609167A (en) * 1962-04-02 1971-09-28 Smith Kline French Lab IBENZO{8 b,e{9 {0 THIEPINES
NL125253C (enExample) * 1963-12-05
NL152845B (nl) * 1966-03-11 1977-04-15 Boehringer Mannheim Gmbh Werkwijze voor het bereiden van een geneesmiddel met een psychotrope en bloedsomloopstimulerende werking, alsmede het aldus verkregen gevormde geneesmiddel, en werkwijze voor het bereiden van een geneeskrachtig omega,omega-difenylalkylaminederivaat.
FR1518226A (fr) * 1966-04-09 1968-03-22 Boehringer & Soehne Gmbh Procédé pour la préparation de dérivés tricy cliques n-alcoylés de l'acétamide
US4463001A (en) * 1980-10-20 1984-07-31 Farmitalia Carlo Erba S.P.A. 6-Substituted 6H-dibenzo[b,d]pyran derivatives and process for their preparation

Also Published As

Publication number Publication date
CA1227481A (fr) 1987-09-29
PT75471B (fr) 1984-11-19
AU8773082A (en) 1983-03-03
ES8400422A1 (es) 1983-11-01
PT75471A (fr) 1982-09-01
NZ201740A (en) 1985-05-31
FR2512024A1 (fr) 1983-03-04
EP0074304B1 (fr) 1985-04-03
JPS6129950B2 (enExample) 1986-07-10
ATE12497T1 (de) 1985-04-15
IL66650A0 (en) 1982-12-31
US4496557A (en) 1985-01-29
ES515232A0 (es) 1983-11-01
GR77595B (enExample) 1984-09-25
EP0074304A1 (fr) 1983-03-16
IL66650A (en) 1985-08-30
FR2512024B1 (enExample) 1984-01-06
ZA826252B (en) 1983-07-27
JPS5874673A (ja) 1983-05-06

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee