DE3260320D1 - (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl) ketone and its salts, its use in therapeutic preparations and process for its production - Google Patents
(2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl) ketone and its salts, its use in therapeutic preparations and process for its productionInfo
- Publication number
- DE3260320D1 DE3260320D1 DE8282400577T DE3260320T DE3260320D1 DE 3260320 D1 DE3260320 D1 DE 3260320D1 DE 8282400577 T DE8282400577 T DE 8282400577T DE 3260320 T DE3260320 T DE 3260320T DE 3260320 D1 DE3260320 D1 DE 3260320D1
- Authority
- DE
- Germany
- Prior art keywords
- dimethoxy
- formula
- piperidinopropyl
- hydroxyphenyl
- ketone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- MVDBGZOSRSXNHU-UHFFFAOYSA-N 1-(4-hydroxy-2,6-dimethoxyphenyl)-4-piperidin-1-ylbutan-1-one Chemical compound COC1=CC(O)=CC(OC)=C1C(=O)CCCN1CCCCC1 MVDBGZOSRSXNHU-UHFFFAOYSA-N 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 abstract 2
- ZNDKGZTXFLTQKE-UHFFFAOYSA-N 2-piperidin-1-ylbutanenitrile Chemical compound CCC(C#N)N1CCCCC1 ZNDKGZTXFLTQKE-UHFFFAOYSA-N 0.000 abstract 1
- XQDNFAMOIPNVES-UHFFFAOYSA-N 3,5-Dimethoxyphenol Chemical compound COC1=CC(O)=CC(OC)=C1 XQDNFAMOIPNVES-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000004658 ketimines Chemical class 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 239000012429 reaction media Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8107597A FR2504136A1 (fr) | 1981-04-15 | 1981-04-15 | (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)-cetone et ses sels d'addition, utilisation en therapeutique et procede de preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3260320D1 true DE3260320D1 (en) | 1984-08-09 |
Family
ID=9257449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8282400577T Expired DE3260320D1 (en) | 1981-04-15 | 1982-03-30 | (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl) ketone and its salts, its use in therapeutic preparations and process for its production |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0063075B1 (es) |
| JP (1) | JPS57181073A (es) |
| AT (1) | ATE8258T1 (es) |
| CA (1) | CA1183853A (es) |
| DE (1) | DE3260320D1 (es) |
| DK (1) | DK156002C (es) |
| ES (1) | ES511431A0 (es) |
| FR (1) | FR2504136A1 (es) |
| GR (1) | GR75918B (es) |
| IE (1) | IE52871B1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2534912B1 (fr) * | 1982-10-26 | 1985-06-28 | Lafon Labor | Nouveaux derives de (2,4,6-trimethoxyphenyl) - (3-piperidinopropyl) -cetone, utilisation en therapeutique et procede de preparation |
| FR2597864B1 (fr) * | 1986-04-28 | 1990-11-16 | Lafon Labor | Nouveaux derives de la n-((trimethoxy-2,4,6-benzoyl)-3 propyl) piperidine, leurs procedes de preparation et leur application en therapeutique |
| JP2569940Y2 (ja) * | 1992-02-14 | 1998-04-28 | 株式会社ヨシコー | 摩擦クラッチ |
| CN1058262C (zh) * | 1993-05-26 | 2000-11-08 | 森德克斯(美国)股份有限公司 | 新颖的1－苯基烷酮5－ht4受体配位体 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2092133B1 (es) * | 1970-05-06 | 1974-03-22 | Orsymonde | |
| FR2134218A1 (en) * | 1971-04-27 | 1972-12-08 | Penciolelli Madeleine | Phloroglucinol aminoketones - vasodilators and antispasmodics |
| GB2004883B (en) * | 1977-09-26 | 1982-03-17 | Lafon Labor | Phloroglucinol derivatives their method of preparation and their use as pharmaceuticals |
| FR2404003A1 (fr) * | 1977-09-26 | 1979-04-20 | Lafon Labor | Nouveaux derives de phloroglucinol, leur procede de preparation et leur application en therapeutique |
-
1981
- 1981-04-15 FR FR8107597A patent/FR2504136A1/fr active Granted
-
1982
- 1982-03-29 IE IE742/82A patent/IE52871B1/en unknown
- 1982-03-30 EP EP82400577A patent/EP0063075B1/fr not_active Expired
- 1982-03-30 DE DE8282400577T patent/DE3260320D1/de not_active Expired
- 1982-03-30 AT AT82400577T patent/ATE8258T1/de not_active IP Right Cessation
- 1982-04-05 CA CA000400489A patent/CA1183853A/en not_active Expired
- 1982-04-06 GR GR67826A patent/GR75918B/el unknown
- 1982-04-14 JP JP57063198A patent/JPS57181073A/ja active Granted
- 1982-04-14 ES ES511431A patent/ES511431A0/es active Granted
- 1982-04-14 DK DK167782A patent/DK156002C/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE8258T1 (de) | 1984-07-15 |
| JPH039112B2 (es) | 1991-02-07 |
| DK167782A (da) | 1982-10-16 |
| IE820742L (en) | 1982-10-15 |
| CA1183853A (en) | 1985-03-12 |
| EP0063075B1 (fr) | 1984-07-04 |
| IE52871B1 (en) | 1988-03-30 |
| ES8304105A1 (es) | 1983-02-16 |
| DK156002C (da) | 1989-11-06 |
| ES511431A0 (es) | 1983-02-16 |
| FR2504136B1 (es) | 1984-02-10 |
| JPS57181073A (en) | 1982-11-08 |
| EP0063075A1 (fr) | 1982-10-20 |
| FR2504136A1 (fr) | 1982-10-22 |
| DK156002B (da) | 1989-06-12 |
| GR75918B (es) | 1984-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8339 | Ceased/non-payment of the annual fee |