DE3210593A1 - Vorrichtung zum messen des oxido-reduktionszustands eines organs am lebenden objekt - Google Patents
Vorrichtung zum messen des oxido-reduktionszustands eines organs am lebenden objektInfo
- Publication number
- DE3210593A1 DE3210593A1 DE19823210593 DE3210593A DE3210593A1 DE 3210593 A1 DE3210593 A1 DE 3210593A1 DE 19823210593 DE19823210593 DE 19823210593 DE 3210593 A DE3210593 A DE 3210593A DE 3210593 A1 DE3210593 A1 DE 3210593A1
- Authority
- DE
- Germany
- Prior art keywords
- axis
- optical
- light
- laser generator
- organ
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 210000000056 organ Anatomy 0.000 title claims description 40
- 230000009467 reduction Effects 0.000 title claims description 5
- 230000003287 optical effect Effects 0.000 claims description 34
- 239000000835 fiber Substances 0.000 claims description 30
- 230000005855 radiation Effects 0.000 claims description 21
- 239000013307 optical fiber Substances 0.000 claims description 17
- 230000005540 biological transmission Effects 0.000 claims description 13
- 238000011156 evaluation Methods 0.000 claims description 13
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 10
- 210000003743 erythrocyte Anatomy 0.000 claims description 7
- 229910052757 nitrogen Inorganic materials 0.000 claims description 5
- 238000005253 cladding Methods 0.000 claims description 3
- 230000001678 irradiating effect Effects 0.000 claims description 3
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- 239000000975 dye Substances 0.000 description 10
- 238000005259 measurement Methods 0.000 description 7
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- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 description 5
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 description 5
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 230000000747 cardiac effect Effects 0.000 description 4
- 229910052710 silicon Inorganic materials 0.000 description 4
- 239000010703 silicon Substances 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000004060 metabolic process Effects 0.000 description 3
- 125000000369 oxido group Chemical group [*]=O 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000000644 propagated effect Effects 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- JKXWXYURKUEZHV-UHFFFAOYSA-M (2z)-1,3,3-trimethyl-2-[(2e)-7-(1,3,3-trimethylindol-1-ium-2-yl)hepta-2,4,6-trienylidene]indole;iodide Chemical compound [I-].CC1(C)C2=CC=CC=C2N(C)C1=CC=CC=CC=CC1=[N+](C)C2=CC=CC=C2C1(C)C JKXWXYURKUEZHV-UHFFFAOYSA-M 0.000 description 1
- WUBBRNOQWQTFEX-UHFFFAOYSA-N 4-aminosalicylic acid Chemical compound NC1=CC=C(C(O)=O)C(O)=C1 WUBBRNOQWQTFEX-UHFFFAOYSA-N 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 238000007675 cardiac surgery Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000001112 coagulating effect Effects 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000013016 damping Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- SBOSGIJGEHWBKV-UHFFFAOYSA-L dioctyltin(2+);dichloride Chemical compound CCCCCCCC[Sn](Cl)(Cl)CCCCCCCC SBOSGIJGEHWBKV-UHFFFAOYSA-L 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000010985 leather Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000033116 oxidation-reduction process Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 238000011477 surgical intervention Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000000844 transformation Methods 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6484—Optical fibres
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- General Physics & Mathematics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Optics & Photonics (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8105948A FR2502783A1 (fr) | 1981-03-25 | 1981-03-25 | Dispositif pour mesurer l'etat d'oxydo-reduction d'un organe vivant in situ |
| FR8202323A FR2521727A2 (fr) | 1981-03-25 | 1982-02-12 | Dispositif pour mesurer l'etat d'oxydo-reduction d'un organe vivant in situ |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3210593A1 true DE3210593A1 (de) | 1982-10-28 |
Family
ID=26222296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19823210593 Withdrawn DE3210593A1 (de) | 1981-03-25 | 1982-03-23 | Vorrichtung zum messen des oxido-reduktionszustands eines organs am lebenden objekt |
Country Status (3)
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4718417A (en) * | 1985-03-22 | 1988-01-12 | Massachusetts Institute Of Technology | Visible fluorescence spectral diagnostic for laser angiosurgery |
| US4913142A (en) * | 1985-03-22 | 1990-04-03 | Massachusetts Institute Of Technology | Catheter for laser angiosurgery |
| US5125404A (en) * | 1985-03-22 | 1992-06-30 | Massachusetts Institute Of Technology | Apparatus and method for obtaining spectrally resolved spatial images of tissue |
| US5199431A (en) * | 1985-03-22 | 1993-04-06 | Massachusetts Institute Of Technology | Optical needle for spectroscopic diagnosis |
| US5304173A (en) * | 1985-03-22 | 1994-04-19 | Massachusetts Institute Of Technology | Spectral diagonostic and treatment system |
| DE4325529A1 (de) * | 1993-07-29 | 1995-02-02 | Pfeiffer Ulrich | Vorrichtung zum Bestimmen der Konzentration von Stoffen im Blut |
| US5419323A (en) * | 1988-12-21 | 1995-05-30 | Massachusetts Institute Of Technology | Method for laser induced fluorescence of tissue |
| US5496305A (en) * | 1985-03-22 | 1996-03-05 | Massachusetts Institue Of Technology | Catheter for laser angiosurgery |
| US6192267B1 (en) * | 1994-03-21 | 2001-02-20 | Scherninski Francois | Endoscopic or fiberscopic imaging device using infrared fluorescence |
| DE10120980A1 (de) * | 2001-05-01 | 2002-11-21 | Pulsion Medical Sys Ag | Verfahren, Vorrichtung und Computerprogramm zur Bestimmung des Blutflusses in einer Gewebe- oder Organregion |
| US7248356B2 (en) | 2004-04-06 | 2007-07-24 | Pulsion Medical Systems Ag | Calibration aid |
| DE102008011013A1 (de) | 2008-02-25 | 2009-09-03 | Labo Tech Labortechnik Gmbh | Verfahren und Einrichtung zur komplexen Stoffwechselanalyse |
| DE102010037406A1 (de) * | 2009-12-25 | 2011-06-30 | Michael Dr. med. 33824 Dickob | Anordnung und Verfahren zur Gewinnung diagnostisch relevanter Parameter von humanem Knorpelgewebe mittels Multiphotonen-Fluoreszenzmikroskopie |
| DE102012002086A1 (de) * | 2012-02-06 | 2013-08-08 | Carl Zeiss Meditec Ag | Verfahren zum Untersuchen von biologischem Gewebe und Vorrichtungen zum Untersuchen und Behandeln des Gewebes |
| EP2510958B1 (en) | 2011-04-11 | 2015-07-22 | Fresenius Medical Care Deutschland GmbH | Method and apparatus for monitoring a treatment of a patient, preferably for monitoring hemodialysis, hemodiafiltration and/or peritoneal dialysis |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8416219D0 (en) * | 1984-06-26 | 1984-08-01 | Antec Systems | Patient monitoring apparatus |
| JPS5940830A (ja) * | 1982-08-31 | 1984-03-06 | 浜松ホトニクス株式会社 | レ−ザ光パルスを用いた癌の診断装置 |
| DE3323365C2 (de) * | 1982-09-04 | 1994-10-20 | Gsf Forschungszentrum Umwelt | Verfahren und Vorrichtung zur Ausleuchtung von Hohlräumen |
| US4553034A (en) * | 1983-12-02 | 1985-11-12 | Westinghouse Electric Corp. | Ion exchange resin intrusion monitor |
| US4622974A (en) * | 1984-03-07 | 1986-11-18 | University Of Tennessee Research Corporation | Apparatus and method for in-vivo measurements of chemical concentrations |
| IT1206462B (it) * | 1984-08-07 | 1989-04-27 | Anic Spa | Fotometro a luce impulsata a lunghezza d'onda multipla per monitoraggio non-invasivo. |
| FR2571604B1 (fr) * | 1984-10-11 | 1989-01-06 | Inst Nat Sante Rech Med | Dispositif pour suivre l'etat d'oxydoreduction d'un organe vivant au cours d'une intervention chirurgicale |
| US4657014A (en) * | 1985-03-11 | 1987-04-14 | Shiley, Inc. | Liquid interface fiberoptic coupler |
| EP0590268B1 (en) * | 1985-03-22 | 1998-07-01 | Massachusetts Institute Of Technology | Fiber Optic Probe System for Spectrally Diagnosing Tissue |
| CN85100424B (zh) * | 1985-04-01 | 1986-10-29 | 上海医疗器械研究所 | 恶性肿瘤固有荧光诊断仪 |
| GB2203831B (en) * | 1986-07-07 | 1991-02-06 | Academy Of Applied Sciences | Apparatus and method for the diagnosis of malignant tumours |
| US5190040A (en) * | 1986-12-26 | 1993-03-02 | Nihon Kohden Corporation | Apparatus for measuring the change in the concentration of a pigment in blood |
| US4894547A (en) * | 1987-09-28 | 1990-01-16 | Yale University | Optical method and apparatus for detecting and measuring aging, photoaging, dermal disease and pigmentation in skin |
| US5111821A (en) * | 1988-11-08 | 1992-05-12 | Health Research, Inc. | Fluorometric method for detecting abnormal tissue using dual long-wavelength excitation |
| US5148022A (en) * | 1989-02-15 | 1992-09-15 | Hitachi, Ltd. | Method for optically inspecting human body and apparatus for the same |
| US5048524A (en) * | 1989-03-03 | 1991-09-17 | Camino Laboratories, Inc. | Blood parameter measurement |
| US5201318A (en) * | 1989-04-24 | 1993-04-13 | Rava Richard P | Contour mapping of spectral diagnostics |
| USH1114H (en) | 1990-04-30 | 1992-12-01 | Medtronic, Inc. | Fiber-optic oxygen saturation/hematocrit sensor |
| US5197470A (en) * | 1990-07-16 | 1993-03-30 | Eastman Kodak Company | Near infrared diagnostic method and instrument |
| NL9001660A (nl) * | 1990-07-20 | 1992-02-17 | Laica Laser Technology Venture | Inrichting voor het detecteren van lucht in de pleura-holte en pneumothorax-detector met deze inrichting. |
| US5166756A (en) * | 1990-11-28 | 1992-11-24 | Nir Systems Incorporated | Powder fiber optic probe having angled end in nir optical analyzing instrument |
| ATE198375T1 (de) | 1991-02-26 | 2001-01-15 | Massachusetts Inst Technology | Molekularspektroskopieverfahren und - einrichtungen zur gewebediagnose |
| US5280788A (en) * | 1991-02-26 | 1994-01-25 | Massachusetts Institute Of Technology | Devices and methods for optical diagnosis of tissue |
| GB9206948D0 (en) * | 1992-03-31 | 1992-05-13 | Kodak Ltd | Optical fibre sensors |
| US5341805A (en) * | 1993-04-06 | 1994-08-30 | Cedars-Sinai Medical Center | Glucose fluorescence monitor and method |
| US5456252A (en) * | 1993-09-30 | 1995-10-10 | Cedars-Sinai Medical Center | Induced fluorescence spectroscopy blood perfusion and pH monitor and method |
| US5503559A (en) * | 1993-09-30 | 1996-04-02 | Cedars-Sinai Medical Center | Fiber-optic endodontic apparatus and method |
| US5541081A (en) * | 1994-03-22 | 1996-07-30 | President And Fellows Of Harvard College | Process for assessing oocyte and embryo quality |
| US5685313A (en) * | 1994-05-31 | 1997-11-11 | Brain Monitor Ltd. | Tissue monitor |
| US5701902A (en) * | 1994-09-14 | 1997-12-30 | Cedars-Sinai Medical Center | Spectroscopic burn injury evaluation apparatus and method |
| DE69631698T2 (de) * | 1995-06-09 | 2004-07-29 | Cybro Medical Ltd. | Sensor,verfahren und vorrichtung für optische blutoxymetrie |
| US5953477A (en) * | 1995-11-20 | 1999-09-14 | Visionex, Inc. | Method and apparatus for improved fiber optic light management |
| US6174424B1 (en) | 1995-11-20 | 2001-01-16 | Cirrex Corp. | Couplers for optical fibers |
| US5764840A (en) * | 1995-11-20 | 1998-06-09 | Visionex, Inc. | Optical fiber with enhanced light collection and illumination and having highly controlled emission and acceptance patterns |
| US6404953B1 (en) | 1996-03-13 | 2002-06-11 | Cirrex Corp. | Optical assembly with high performance filter |
| US6208783B1 (en) | 1997-03-13 | 2001-03-27 | Cirrex Corp. | Optical filtering device |
| US5901261A (en) * | 1997-06-19 | 1999-05-04 | Visionex, Inc. | Fiber optic interface for optical probes with enhanced photonic efficiency, light manipulation, and stray light rejection |
| US20030135122A1 (en) * | 1997-12-12 | 2003-07-17 | Spectrx, Inc. | Multi-modal optical tissue diagnostic system |
| US6055451A (en) * | 1997-12-12 | 2000-04-25 | Spectrx, Inc. | Apparatus and method for determining tissue characteristics |
| EP1112022A4 (en) * | 1998-09-11 | 2004-08-04 | Spectrx Inc | MULTI-MODAL OPTICAL TISSUE DIAGNOSIS DEVICE |
| JP5088990B2 (ja) * | 1999-01-26 | 2012-12-05 | Ｈｏｙａ株式会社 | 内視鏡用の自己蛍光画像化システム |
| US6580935B1 (en) | 1999-03-12 | 2003-06-17 | Cirrex Corp. | Method and system for stabilizing reflected light |
| US20040147843A1 (en) * | 1999-11-05 | 2004-07-29 | Shabbir Bambot | System and method for determining tissue characteristics |
| ATE346540T1 (de) * | 2000-05-19 | 2006-12-15 | Coherent Gmbh | Vorrichtung und verfahren zur erkennung von tumorösem gewebe |
| US6821245B2 (en) | 2000-07-14 | 2004-11-23 | Xillix Technologies Corporation | Compact fluorescence endoscopy video system |
| IL138683A0 (en) * | 2000-09-25 | 2001-10-31 | Vital Medical Ltd | Apparatus and method for monitoring tissue vitality parameters |
| US20050043606A1 (en) * | 2001-09-25 | 2005-02-24 | Eliahu Pewzner | Multiparametric apparatus for monitoring multiple tissue vitality parameters |
| US20060241496A1 (en) * | 2002-01-15 | 2006-10-26 | Xillix Technologies Corp. | Filter for use with imaging endoscopes |
| US20050154319A1 (en) * | 2002-01-15 | 2005-07-14 | Xillix Technologies Corporation | Fluorescence endoscopy video systems with no moving parts in the camera |
| US6899675B2 (en) * | 2002-01-15 | 2005-05-31 | Xillix Technologies Corp. | Fluorescence endoscopy video systems with no moving parts in the camera |
| IL148795A0 (en) * | 2002-03-20 | 2002-09-12 | Vital Medical Ltd | Apparatus and method for monitoring tissue vitality parameters for the diagnosis of body metabolic emergency state |
| US20060161055A1 (en) * | 2002-03-20 | 2006-07-20 | Critisense, Ltd. | Probe design |
| US9440046B2 (en) | 2002-04-04 | 2016-09-13 | Angiodynamics, Inc. | Venous insufficiency treatment method |
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| US7763058B2 (en) * | 2004-11-20 | 2010-07-27 | Dick Sterenborg | Device and method for photodynamic therapy of the nasopharyngeal cavity |
| WO2007002323A2 (en) * | 2005-06-23 | 2007-01-04 | Epoc, Inc. | System and method for monitoring of end organ oxygenation by measurement of in vivo cellular energy status |
| WO2007106624A2 (en) | 2006-02-07 | 2007-09-20 | Novadaq Technologies Inc. | Near infrared imaging |
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| KR101723762B1 (ko) | 2011-03-08 | 2017-04-06 | 노바다크 테크놀러지즈 인코포레이티드 | 풀 스펙트럼 led 조명기 |
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| US10638960B2 (en) | 2015-10-26 | 2020-05-05 | Reveal Biosensors, Inc. | Optical physiologic sensor methods |
| JP6743137B2 (ja) | 2015-11-13 | 2020-08-19 | ノバダック テクノロジーズ ユーエルシー | ターゲットの照明およびイメージングのためのシステムおよび方法 |
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| CA3027592A1 (en) | 2016-06-14 | 2017-12-21 | John Josef Paul FENGLER | Methods and systems for adaptive imaging for low light signal enhancement in medical visualization |
| EP3580609B1 (en) | 2017-02-10 | 2023-05-24 | Stryker European Operations Limited | Open-field handheld fluorescence imaging systems and methods |
| US12376904B1 (en) | 2020-09-08 | 2025-08-05 | Angiodynamics, Inc. | Dynamic laser stabilization and calibration system |
| US12038322B2 (en) | 2022-06-21 | 2024-07-16 | Eximo Medical Ltd. | Devices and methods for testing ablation systems |
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- 1982-03-25 US US06/362,012 patent/US4449535A/en not_active Expired - Fee Related
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| US3136310A (en) * | 1960-01-18 | 1964-06-09 | Bausch & Lomb | Optical catheter |
| US3769963A (en) * | 1972-03-31 | 1973-11-06 | L Goldman | Instrument for performing laser micro-surgery and diagnostic transillumination of living human tissue |
| US3830222A (en) * | 1972-07-07 | 1974-08-20 | Johnson Res Foundation | Method and apparatus for observing rates of reaction of oxygen in living tissues |
| US4223680A (en) * | 1977-06-28 | 1980-09-23 | Duke University, Inc. | Method and apparatus for monitoring metabolism in body organs in vivo |
| US4222389A (en) * | 1977-10-18 | 1980-09-16 | Institute Of Applied Biology Special Cancer Research Project | Objective determination of the rate of oxygen utilization in peripheral tissue |
| DE2916323A1 (de) * | 1978-04-24 | 1979-10-25 | Univ Hokkaido | Vorrichtung zur durchfuehrung optischer messungen an einem lebenden koerper |
Cited By (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4718417A (en) * | 1985-03-22 | 1988-01-12 | Massachusetts Institute Of Technology | Visible fluorescence spectral diagnostic for laser angiosurgery |
| US4913142A (en) * | 1985-03-22 | 1990-04-03 | Massachusetts Institute Of Technology | Catheter for laser angiosurgery |
| US5125404A (en) * | 1985-03-22 | 1992-06-30 | Massachusetts Institute Of Technology | Apparatus and method for obtaining spectrally resolved spatial images of tissue |
| US5199431A (en) * | 1985-03-22 | 1993-04-06 | Massachusetts Institute Of Technology | Optical needle for spectroscopic diagnosis |
| US5304173A (en) * | 1985-03-22 | 1994-04-19 | Massachusetts Institute Of Technology | Spectral diagonostic and treatment system |
| US5318024A (en) * | 1985-03-22 | 1994-06-07 | Massachusetts Institute Of Technology | Laser endoscope for spectroscopic imaging |
| US5496305A (en) * | 1985-03-22 | 1996-03-05 | Massachusetts Institue Of Technology | Catheter for laser angiosurgery |
| US5419323A (en) * | 1988-12-21 | 1995-05-30 | Massachusetts Institute Of Technology | Method for laser induced fluorescence of tissue |
| US5562100A (en) * | 1988-12-21 | 1996-10-08 | Massachusetts Institute Of Technology | Method for laser induced fluorescence of tissue |
| DE4325529A1 (de) * | 1993-07-29 | 1995-02-02 | Pfeiffer Ulrich | Vorrichtung zum Bestimmen der Konzentration von Stoffen im Blut |
| US6192267B1 (en) * | 1994-03-21 | 2001-02-20 | Scherninski Francois | Endoscopic or fiberscopic imaging device using infrared fluorescence |
| DE10120980A1 (de) * | 2001-05-01 | 2002-11-21 | Pulsion Medical Sys Ag | Verfahren, Vorrichtung und Computerprogramm zur Bestimmung des Blutflusses in einer Gewebe- oder Organregion |
| US6853857B2 (en) | 2001-05-01 | 2005-02-08 | Pulsion Medical Systems Ag | Method, device and computer program for determining the blood flow in a tissue or organ region |
| DE10120980B4 (de) * | 2001-05-01 | 2009-12-03 | Pulsion Medical Systems Ag | Verfahren, Vorrichtung und Computerprogramm zur Bestimmung des Blutflusses in einer Gewebe- oder Organregion |
| US7248356B2 (en) | 2004-04-06 | 2007-07-24 | Pulsion Medical Systems Ag | Calibration aid |
| DE102008011013A1 (de) | 2008-02-25 | 2009-09-03 | Labo Tech Labortechnik Gmbh | Verfahren und Einrichtung zur komplexen Stoffwechselanalyse |
| DE102008011013B4 (de) * | 2008-02-25 | 2014-11-13 | Mevitec Gmbh | Verfahren und Einrichtung zur komplexen Stoffwechselanalyse |
| DE102010037406A1 (de) * | 2009-12-25 | 2011-06-30 | Michael Dr. med. 33824 Dickob | Anordnung und Verfahren zur Gewinnung diagnostisch relevanter Parameter von humanem Knorpelgewebe mittels Multiphotonen-Fluoreszenzmikroskopie |
| EP2510958B1 (en) | 2011-04-11 | 2015-07-22 | Fresenius Medical Care Deutschland GmbH | Method and apparatus for monitoring a treatment of a patient, preferably for monitoring hemodialysis, hemodiafiltration and/or peritoneal dialysis |
| EP2510958B2 (en) † | 2011-04-11 | 2023-02-15 | Fresenius Medical Care Deutschland GmbH | Method and apparatus for monitoring a treatment of a patient, preferably for monitoring hemodialysis, hemodiafiltration and/or peritoneal dialysis |
| DE102012002086A1 (de) * | 2012-02-06 | 2013-08-08 | Carl Zeiss Meditec Ag | Verfahren zum Untersuchen von biologischem Gewebe und Vorrichtungen zum Untersuchen und Behandeln des Gewebes |
| US9883804B2 (en) | 2012-02-06 | 2018-02-06 | Carl Zeiss Meditec Ag | Method and device for examining a biological tissue by analysing fluorescence response to illumination and for treating the tissue |
| US10973411B2 (en) | 2012-02-06 | 2021-04-13 | Carl Zeiss Meditec Ag | Method and device for examining a biological tissue by analysing fluorescence response to illumination and for treating the tissue |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2521727A2 (fr) | 1983-08-19 |
| US4449535A (en) | 1984-05-22 |
| FR2521727B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-12-07 |
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