DE3166872D1 - 3-keto-delta-4 or delta-1,4 steroid derivatives substituted at position 7, their preparation, their utilization as pharmaceutical compositions, and compositions containing them - Google Patents

3-keto-delta-4 or delta-1,4 steroid derivatives substituted at position 7, their preparation, their utilization as pharmaceutical compositions, and compositions containing them

Info

Publication number
DE3166872D1
DE3166872D1 DE8181401994T DE3166872T DE3166872D1 DE 3166872 D1 DE3166872 D1 DE 3166872D1 DE 8181401994 T DE8181401994 T DE 8181401994T DE 3166872 T DE3166872 T DE 3166872T DE 3166872 D1 DE3166872 D1 DE 3166872D1
Authority
DE
Germany
Prior art keywords
group
delta
free
preparation
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181401994T
Other languages
English (en)
Inventor
Lucien Nedelec
Vesperto Torelli
Daniel Philibert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Application granted granted Critical
Publication of DE3166872D1 publication Critical patent/DE3166872D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0088Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0033Androstane derivatives substituted in position 17 alfa and 17 beta
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001Lactones
    • C07J21/003Lactones at position 17
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
DE8181401994T 1980-12-23 1981-12-14 3-keto-delta-4 or delta-1,4 steroid derivatives substituted at position 7, their preparation, their utilization as pharmaceutical compositions, and compositions containing them Expired DE3166872D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8027272A FR2496669A1 (fr) 1980-12-23 1980-12-23 Nouveaux derives steroides 3-ceto4 ou1-4 substitues en position 7, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
DE3166872D1 true DE3166872D1 (en) 1984-11-29

Family

ID=9249374

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181401994T Expired DE3166872D1 (en) 1980-12-23 1981-12-14 3-keto-delta-4 or delta-1,4 steroid derivatives substituted at position 7, their preparation, their utilization as pharmaceutical compositions, and compositions containing them

Country Status (19)

Country Link
US (1) US4396614A (de)
EP (1) EP0055170B1 (de)
JP (1) JPS57163399A (de)
KR (1) KR870001937B1 (de)
AT (1) ATE10004T1 (de)
AU (1) AU549260B2 (de)
CA (1) CA1196910A (de)
DE (1) DE3166872D1 (de)
DK (1) DK569281A (de)
ES (2) ES8401989A1 (de)
FI (1) FI77463C (de)
FR (1) FR2496669A1 (de)
GR (1) GR77629B (de)
HU (1) HU184974B (de)
IE (1) IE52462B1 (de)
IL (1) IL64503A0 (de)
PT (1) PT74184B (de)
SU (1) SU1301317A3 (de)
ZA (1) ZA818673B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4501695A (en) * 1983-05-16 1985-02-26 The Upjohn Company Spironalactone process
FR2596395B1 (fr) * 1986-03-26 1989-05-26 Roussel Uclaf Nouveaux steroides comportant un cycle spirannique en position 17, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
US5276023A (en) * 1989-08-08 1994-01-04 Roussel Uclaf 19-nor-steroid esters
PL2532648T3 (pl) 2007-05-03 2014-07-31 Univ Yale Działające miejscowo „miękkie” antyandrogeny

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3053840A (en) * 1960-06-23 1962-09-11 Searle & Co 11-oxygenated polydehydro 17-carboxyethyl-9-halo-17-hydroxyandrostan-3-one lactones
BE787940A (fr) * 1971-08-25 1973-02-26 Searle & Co Nouveaux medicaments diuretiques et hypotenseurs et procede de leur preparation
US3845041A (en) * 1973-12-26 1974-10-29 Searle & Co 7-halomethyl-17-hydroxy-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid gamma-lactones
FR2451923A1 (fr) * 1979-03-22 1980-10-17 Roussel Uclaf Nouveaux derives steroides 7-alkyles, leur procede de preparation et leur application comme medicament

Also Published As

Publication number Publication date
ES507890A0 (es) 1984-01-01
AU549260B2 (en) 1986-01-23
ES516143A0 (es) 1983-08-01
FR2496669B1 (de) 1983-10-28
FR2496669A1 (fr) 1982-06-25
PT74184A (fr) 1982-01-01
JPH0133115B2 (de) 1989-07-11
ATE10004T1 (de) 1984-11-15
IE52462B1 (en) 1987-11-11
ES8307837A1 (es) 1983-08-01
AU7877281A (en) 1982-07-01
FI77463B (fi) 1988-11-30
FI814109L (fi) 1982-06-24
IE813077L (en) 1982-06-23
FI77463C (fi) 1989-03-10
PT74184B (fr) 1984-01-05
DK569281A (da) 1982-06-24
JPS57163399A (en) 1982-10-07
ZA818673B (en) 1982-10-27
HU184974B (en) 1984-11-28
SU1301317A3 (ru) 1987-03-30
ES8401989A1 (es) 1984-01-01
EP0055170B1 (de) 1984-10-24
US4396614A (en) 1983-08-02
KR870001937B1 (ko) 1987-10-22
KR830007713A (ko) 1983-11-04
EP0055170A1 (de) 1982-06-30
IL64503A0 (en) 1982-03-31
GR77629B (de) 1984-09-25
CA1196910A (fr) 1985-11-19

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee