DE3149710A1 - Heterocyclische verbindungen, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen - Google Patents

Heterocyclische verbindungen, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen

Info

Publication number
DE3149710A1
DE3149710A1 DE19813149710 DE3149710A DE3149710A1 DE 3149710 A1 DE3149710 A1 DE 3149710A1 DE 19813149710 DE19813149710 DE 19813149710 DE 3149710 A DE3149710 A DE 3149710A DE 3149710 A1 DE3149710 A1 DE 3149710A1
Authority
DE
Germany
Prior art keywords
pyrazoline
group
substituted
trifluoromethylphenyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19813149710
Other languages
German (de)
English (en)
Inventor
Albert Gordon West Wickham Kent Caldwell
David Beckenham Kent Collard
Frederick Charles Beckenham Kent Copp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of DE3149710A1 publication Critical patent/DE3149710A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/76—Nitrogen atoms to which a second hetero atom is attached
    • C07D213/77—Hydrazine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19813149710 1980-12-16 1981-12-15 Heterocyclische verbindungen, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen Withdrawn DE3149710A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8040172 1980-12-16
US25607281A 1981-04-21 1981-04-21

Publications (1)

Publication Number Publication Date
DE3149710A1 true DE3149710A1 (de) 1982-08-05

Family

ID=26277856

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8181110457T Expired DE3173933D1 (en) 1980-12-16 1981-12-15 Pyrazoline derivatives, processes for their preparation and pharmaceutical formulations containing them
DE19813149710 Withdrawn DE3149710A1 (de) 1980-12-16 1981-12-15 Heterocyclische verbindungen, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE8181110457T Expired DE3173933D1 (en) 1980-12-16 1981-12-15 Pyrazoline derivatives, processes for their preparation and pharmaceutical formulations containing them

Country Status (18)

Country Link
EP (1) EP0055418B1 (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
AT (1) AT379803B (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
AU (1) AU559488B2 (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
CA (1) CA1180335A (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
CH (1) CH654209A5 (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
DE (2) DE3173933D1 (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
DK (1) DK556381A (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
ES (1) ES507975A0 (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
FI (1) FI814024L (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
FR (1) FR2496100B1 (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
GR (1) GR76989B (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
HU (1) HU187392B (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
IE (1) IE51951B1 (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
IL (1) IL64555A (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
MC (1) MC1435A1 (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
NL (1) NL8105652A (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
NZ (1) NZ199288A (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
SE (1) SE8107524L (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0070376A1 (en) * 1981-07-13 1983-01-26 American Cyanamid Company Heterocyclic substituted-amino-pyrazolines
EP0119450A1 (en) * 1983-02-11 1984-09-26 The Wellcome Foundation Limited Preparation of aminopyrazolines and intermediates used therein
GB8303782D0 (en) * 1983-02-11 1983-03-16 Wellcome Found Heterocyclic compounds
US4824859A (en) * 1983-05-21 1989-04-25 Fisons Plc. Pyrazoline compounds compositions and use
DE3575130D1 (de) * 1984-05-12 1990-02-08 Fisons Plc Antiinflammatorische 1,n-diarylpyrazol-3-amine, deren zusammensetzungen und verfahren zu deren herstellung.
US4970210A (en) * 1987-07-17 1990-11-13 Abbott Laboratories Triazinone lipoxygenase compounds
FR2781147B1 (fr) 1998-07-20 2000-09-15 Oreal Compositions pour la teinture des fibres keratiniques contenant des derives de 3-amino pyrazolines a titre de coupleur, procede de teinture et kit de teinture
GB0603181D0 (en) * 2006-02-17 2006-03-29 Merck Sharp & Dohme Treatment of neurodegenerative and psychiatric diseases
WO2025166015A2 (en) * 2024-02-02 2025-08-07 Photys Therapeutics, Inc. Bifunctional abl1-binding compounds and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES313450A1 (es) * 1964-05-27 1966-02-16 Geigy Ag J R Procedimiento para la preparacion de compuestos de pirazolina.
FR2059449A1 (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html) * 1969-02-26 1971-06-04 Synthelabo
IT1207128B (it) * 1979-07-13 1989-05-17 Wellcome Found Composizioni farmaceutiche contenenti composti eterociclici derivati dalla pirazolina ad attivita'anti spasmodica e procedimento per laloro preparazione

Also Published As

Publication number Publication date
IE51951B1 (en) 1987-04-29
ES8307224A1 (es) 1983-06-16
CA1180335A (en) 1985-01-02
FR2496100A1 (fr) 1982-06-18
CH654209A5 (de) 1986-02-14
ES507975A0 (es) 1983-06-16
EP0055418A3 (en) 1982-08-18
AU559488B2 (en) 1987-03-12
AT379803B (de) 1986-03-10
SE8107524L (sv) 1982-06-17
HU187392B (en) 1985-12-28
GR76989B (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html) 1984-09-04
FI814024A7 (fi) 1982-06-17
FR2496100B1 (fr) 1985-06-14
MC1435A1 (fr) 1982-12-06
EP0055418A2 (en) 1982-07-07
ATA537281A (de) 1985-07-15
NZ199288A (en) 1985-07-31
DE3173933D1 (en) 1986-04-03
EP0055418B1 (en) 1986-02-26
IL64555A0 (en) 1982-03-31
IE812944L (en) 1982-06-16
DK556381A (da) 1982-06-17
NL8105652A (nl) 1982-07-16
IL64555A (en) 1986-01-31
AU7851081A (en) 1982-06-24
FI814024L (fi) 1982-06-17

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee