DE2960689D1 - Fluorene and fluoranthene derivatives, process for their preparation and their therapeutic application - Google Patents

Fluorene and fluoranthene derivatives, process for their preparation and their therapeutic application

Info

Publication number
DE2960689D1
DE2960689D1 DE7979400459T DE2960689T DE2960689D1 DE 2960689 D1 DE2960689 D1 DE 2960689D1 DE 7979400459 T DE7979400459 T DE 7979400459T DE 2960689 T DE2960689 T DE 2960689T DE 2960689 D1 DE2960689 D1 DE 2960689D1
Authority
DE
Germany
Prior art keywords
alkyl
radical
hydrogen atom
fluorene
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979400459T
Other languages
German (de)
English (en)
Inventor
Regis Dupont
Patrick Andre Louis Lardenois
Claude Constant Henri Morel
Jonathan Reid Frost
Gabor Itsvan Koletar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7822353A external-priority patent/FR2432026A1/fr
Priority claimed from FR7822352A external-priority patent/FR2432025A1/fr
Application filed by Synthelabo SA filed Critical Synthelabo SA
Application granted granted Critical
Publication of DE2960689D1 publication Critical patent/DE2960689D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE7979400459T 1978-07-28 1979-07-05 Fluorene and fluoranthene derivatives, process for their preparation and their therapeutic application Expired DE2960689D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7822353A FR2432026A1 (fr) 1978-07-28 1978-07-28 Derives de fluorenes et de fluoranthenes et leur application en therapeutique
FR7822352A FR2432025A1 (fr) 1978-07-28 1978-07-28 Derives d'imidazo et de pyrimido-pyrido-indoles, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
DE2960689D1 true DE2960689D1 (en) 1981-11-19

Family

ID=26220699

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979400459T Expired DE2960689D1 (en) 1978-07-28 1979-07-05 Fluorene and fluoranthene derivatives, process for their preparation and their therapeutic application

Country Status (13)

Country Link
US (1) US4277476A (enExample)
EP (1) EP0008249B1 (enExample)
AT (1) ATE165T1 (enExample)
AU (1) AU524307B2 (enExample)
CA (1) CA1107729A (enExample)
DE (1) DE2960689D1 (enExample)
DK (1) DK316279A (enExample)
ES (1) ES482889A1 (enExample)
FI (1) FI65250C (enExample)
GR (1) GR75070B (enExample)
NO (1) NO792476L (enExample)
NZ (1) NZ191141A (enExample)
PT (1) PT69988A (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2455044A1 (fr) * 1979-04-26 1980-11-21 Synthelabo Pyrido-indoles et leur application en therapeutique
US4367230A (en) * 1980-01-04 1983-01-04 Tanabe Seiyaku Co., Ltd. Novel triazafluoranthene compound and processes for preparing the same
US4428880A (en) 1981-05-04 1984-01-31 S.A. Omnichem Azepino[4,5-d]indole derivatives and preparation thereof
FR2594070B1 (fr) * 1985-12-19 1991-06-14 Braas & Co Gmbh Materiau composite deformable pour le recouvrement dans l'industrie du batiment
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
PL1737461T3 (pl) 2004-03-15 2013-05-31 Ptc Therapeutics Inc Pochodne karbolinowe użyteczne w hamowaniu angiogenezy
US8076353B2 (en) 2004-03-15 2011-12-13 Ptc Therapeutics, Inc. Inhibition of VEGF translation
US7767689B2 (en) 2004-03-15 2010-08-03 Ptc Therapeutics, Inc. Carboline derivatives useful in the treatment of cancer
US8076352B2 (en) 2004-03-15 2011-12-13 Ptc Therapeutics, Inc. Administration of carboline derivatives useful in the treatment of cancer and other diseases
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
WO2010095940A2 (en) 2009-02-20 2010-08-26 To-Bbb Holding B.V. Glutathione-based drug delivery system
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2556574A (en) * 1949-06-24 1951-06-12 Allen & Hanburys Ltd Indolopteridines and process for preparing same
US3108108A (en) * 1959-09-25 1963-10-22 Bayer Ag Aza analogues of polynuclear o-quinones
US3122544A (en) * 1962-11-13 1964-02-25 American Home Prod 4-amino-2-aryl-6h-indeno(2, 3-g)-pteridin-6-ones
US3470181A (en) * 1967-10-23 1969-09-30 American Home Prod Fused 2-pyrimidinepropionic acid compounds,related compounds,and the process for their preparation
US3631046A (en) * 1969-05-28 1971-12-28 Sandoz Ag Tetracyclic quinazolin-ones
BE759337A (fr) * 1969-11-24 1971-05-24 Lilly Co Eli Benzimidazol (2,1-b)-quinazolin (6h) ones qui sont des immuno-depresseurs, et nouvelles benzimidazo (2,1-b) quinazolin-12-(6h) ones
US3963720A (en) * 1972-10-27 1976-06-15 Sandoz, Inc. Tetracyclic imidazo [2,1-b] quinazolinone derivatives
CH601299A5 (en) * 1973-11-07 1978-07-14 Vni Khim Farmatsevtichesky I I Pyrazino(1,2,3-ab)beta carbolines and homologues

Also Published As

Publication number Publication date
EP0008249B1 (fr) 1981-08-26
FI792366A7 (fi) 1980-01-29
US4277476A (en) 1981-07-07
AU4927879A (en) 1980-01-31
ATE165T1 (de) 1981-09-15
PT69988A (fr) 1979-08-01
EP0008249A2 (fr) 1980-02-20
FI65250C (fi) 1984-04-10
GR75070B (enExample) 1984-07-13
FI65250B (fi) 1983-12-30
ES482889A1 (es) 1980-04-16
NZ191141A (en) 1983-02-15
CA1107729A (en) 1981-08-25
EP0008249A3 (en) 1980-05-14
NO792476L (no) 1980-01-29
DK316279A (da) 1980-01-29
AU524307B2 (en) 1982-09-09

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee