DE2930706A1 - Verfahren zum nachweis von erregerspezifischen antikoerpern - Google Patents
Verfahren zum nachweis von erregerspezifischen antikoerpernInfo
- Publication number
- DE2930706A1 DE2930706A1 DE19792930706 DE2930706A DE2930706A1 DE 2930706 A1 DE2930706 A1 DE 2930706A1 DE 19792930706 DE19792930706 DE 19792930706 DE 2930706 A DE2930706 A DE 2930706A DE 2930706 A1 DE2930706 A1 DE 2930706A1
- Authority
- DE
- Germany
- Prior art keywords
- antibodies
- enzyme
- labeled
- antigen
- specific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 title claims abstract description 20
- 239000000427 antigen Substances 0.000 claims abstract description 33
- 102000036639 antigens Human genes 0.000 claims abstract description 31
- 108091007433 antigens Proteins 0.000 claims abstract description 31
- 102000004190 Enzymes Human genes 0.000 claims abstract description 21
- 108090000790 Enzymes Proteins 0.000 claims abstract description 21
- 210000002966 serum Anatomy 0.000 claims abstract description 16
- 239000007787 solid Substances 0.000 claims abstract description 7
- 230000000694 effects Effects 0.000 claims abstract description 3
- 244000052769 pathogen Species 0.000 claims description 13
- 238000001514 detection method Methods 0.000 claims description 12
- 238000009739 binding Methods 0.000 claims description 10
- 230000027455 binding Effects 0.000 claims description 8
- 108040007629 peroxidase activity proteins Proteins 0.000 claims description 8
- 230000001717 pathogenic effect Effects 0.000 claims description 5
- 102000003992 Peroxidases Human genes 0.000 claims description 3
- 238000003776 cleavage reaction Methods 0.000 claims description 3
- 230000007017 scission Effects 0.000 claims description 3
- 239000000470 constituent Substances 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
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- 238000010790 dilution Methods 0.000 abstract description 6
- 239000012895 dilution Substances 0.000 abstract description 6
- 238000003018 immunoassay Methods 0.000 abstract description 2
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- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 238000004440 column chromatography Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 8
- 239000002953 phosphate buffered saline Substances 0.000 description 8
- 238000006243 chemical reaction Methods 0.000 description 7
- 108060003951 Immunoglobulin Proteins 0.000 description 6
- 102000018358 immunoglobulin Human genes 0.000 description 6
- 102000013415 peroxidase activity proteins Human genes 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 102000014914 Carrier Proteins Human genes 0.000 description 4
- 108091008324 binding proteins Proteins 0.000 description 4
- 239000012153 distilled water Substances 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 241000700605 Viruses Species 0.000 description 3
- 244000309466 calf Species 0.000 description 3
- 238000002372 labelling Methods 0.000 description 3
- 239000006228 supernatant Substances 0.000 description 3
- 230000003612 virological effect Effects 0.000 description 3
- 229920002307 Dextran Polymers 0.000 description 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 2
- 229920001213 Polysorbate 20 Polymers 0.000 description 2
- 239000007983 Tris buffer Substances 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 2
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 2
- 229920000915 polyvinyl chloride Polymers 0.000 description 2
- 239000004800 polyvinyl chloride Substances 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000013049 sediment Substances 0.000 description 2
- 230000009870 specific binding Effects 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- GEYOCULIXLDCMW-UHFFFAOYSA-N 1,2-phenylenediamine Chemical compound NC1=CC=CC=C1N GEYOCULIXLDCMW-UHFFFAOYSA-N 0.000 description 1
- 102000009027 Albumins Human genes 0.000 description 1
- 108010088751 Albumins Proteins 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- QUSNBJAOOMFDIB-UHFFFAOYSA-N Ethylamine Chemical compound CCN QUSNBJAOOMFDIB-UHFFFAOYSA-N 0.000 description 1
- 102000009109 Fc receptors Human genes 0.000 description 1
- 108010087819 Fc receptors Proteins 0.000 description 1
- 241000709721 Hepatovirus A Species 0.000 description 1
- 108010001336 Horseradish Peroxidase Proteins 0.000 description 1
- 240000007817 Olea europaea Species 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 108700020962 Peroxidase Proteins 0.000 description 1
- BELBBZDIHDAJOR-UHFFFAOYSA-N Phenolsulfonephthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2S(=O)(=O)O1 BELBBZDIHDAJOR-UHFFFAOYSA-N 0.000 description 1
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 description 1
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 description 1
- 229920001214 Polysorbate 60 Polymers 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 241000710799 Rubella virus Species 0.000 description 1
- 239000007984 Tris EDTA buffer Substances 0.000 description 1
- LWZFANDGMFTDAV-BURFUSLBSA-N [(2r)-2-[(2r,3r,4s)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] dodecanoate Chemical compound CCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O LWZFANDGMFTDAV-BURFUSLBSA-N 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000003460 anti-nuclear Effects 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 210000003850 cellular structure Anatomy 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000011162 core material Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
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- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000006911 enzymatic reaction Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000010166 immunofluorescence Methods 0.000 description 1
- 229940072221 immunoglobulins Drugs 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000008774 maternal effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 150000002978 peroxides Chemical class 0.000 description 1
- 229960003531 phenolsulfonphthalein Drugs 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000007974 sodium acetate buffer Substances 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 229950006451 sorbitan laurate Drugs 0.000 description 1
- 235000011067 sorbitan monolaureate Nutrition 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/586—Liposomes, microcapsules or cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792930706 DE2930706A1 (de) | 1979-07-28 | 1979-07-28 | Verfahren zum nachweis von erregerspezifischen antikoerpern |
| US06/165,395 US4347311A (en) | 1979-07-28 | 1980-07-02 | Enzyme immunoassay for determining antigen specific antibodies and test kit for carrying out this assay |
| DE8080104220T DE3065997D1 (en) | 1979-07-28 | 1980-07-18 | Enzyme-immuno assay for the detection of pathogen specific antibodies and test-kit for performing this assay |
| EP80104220A EP0023989B1 (de) | 1979-07-28 | 1980-07-18 | Enzym-Immuntest zum Nachweis von Erreger-spezifischen Antikörpern und Testsatz für die Durchführung dieses Tests |
| AT80104220T ATE5747T1 (de) | 1979-07-28 | 1980-07-18 | Enzym-immuntest zum nachweis von erregerspezifischen antikoerpern und testsatz fuer die durchfuehrung dieses tests. |
| JP10042280A JPS5621065A (en) | 1979-07-28 | 1980-07-22 | Enzyme immunoassary for determining antigennspecific antibody and test kit for same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792930706 DE2930706A1 (de) | 1979-07-28 | 1979-07-28 | Verfahren zum nachweis von erregerspezifischen antikoerpern |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2930706A1 true DE2930706A1 (de) | 1981-02-05 |
Family
ID=6077040
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19792930706 Withdrawn DE2930706A1 (de) | 1979-07-28 | 1979-07-28 | Verfahren zum nachweis von erregerspezifischen antikoerpern |
| DE8080104220T Expired DE3065997D1 (en) | 1979-07-28 | 1980-07-18 | Enzyme-immuno assay for the detection of pathogen specific antibodies and test-kit for performing this assay |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8080104220T Expired DE3065997D1 (en) | 1979-07-28 | 1980-07-18 | Enzyme-immuno assay for the detection of pathogen specific antibodies and test-kit for performing this assay |
Country Status (5)
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4447528A (en) * | 1981-08-10 | 1984-05-08 | Corning Glass Works | Detecting intrinsic factor blocking site antibody |
| JPS5856696A (ja) * | 1981-09-30 | 1983-04-04 | Amano Pharmaceut Co Ltd | カラムを用いる酵素免疫測定法 |
| US4434227A (en) | 1982-02-08 | 1984-02-28 | Abbott Laboratories | Immunoassay for class specific immunoglobulin antibodies |
| US4454226A (en) * | 1982-03-17 | 1984-06-12 | Majid Ali | Enzymatic immunoassay |
| CA1240937A (en) * | 1982-07-26 | 1988-08-23 | Gordon R. Dreesman | Monoclonal igm antibodies and method of preparation |
| US4659678A (en) * | 1982-09-29 | 1987-04-21 | Serono Diagnostics Limited | Immunoassay of antigens |
| US4845027B1 (en) * | 1982-10-13 | 1994-05-10 | Biowhittaker Inc | Fluorometric assay of allergic reactions |
| US4528267A (en) * | 1982-11-26 | 1985-07-09 | Axionics, Inc. | Fluorometirc enzyme inhibition immunoassay for measuring potency of allergen extracts |
| US4849337A (en) * | 1983-01-31 | 1989-07-18 | Minnesota Mining And Manufacturing Company | Assaying allergen specific IgE levels with fluorogenic enzyme labeled antibody |
| US4727037A (en) * | 1984-02-15 | 1988-02-23 | Cetus Corporation | Assay kit and method for the determination of antibody class and subclass |
| EP0175761A4 (en) * | 1984-03-19 | 1986-09-24 | Marius Constantin Teodorescu | BACTERIOPHAGES SERVING RECOGNITION AND IDENTIFICATION AGENTS. |
| US4797363A (en) * | 1984-03-19 | 1989-01-10 | Board Of Trustees, University Of Illinois | Bacteriophages as recognition and identification agents |
| US4617265A (en) * | 1984-09-19 | 1986-10-14 | Board Of Regents, University Of Texas System | Colony blot assay for enterotoxigenic bacteria |
| US4935339A (en) * | 1985-05-07 | 1990-06-19 | Nichols Institute Diagnostics | Delayed solid phase immunologic assay |
| WO1986007463A1 (en) * | 1985-06-03 | 1986-12-18 | American National Red Cross | Microtiter - surface - flocculation assay for antigen or antibody screening |
| DE3717401A1 (de) * | 1987-05-23 | 1988-12-08 | Behringwerke Ag | Einschritt-immuntest zur bestimmung von antigen-spezifischen antikoerpern aus einer der immunglobulin-klassen a, m, d oder e und dazu geeignetes mittel |
| US5759774A (en) * | 1988-05-18 | 1998-06-02 | Cobe Laboratories, Inc. | Method of detecting circulating antibody types using dried or lyophilized cells |
| US5281522A (en) * | 1988-09-15 | 1994-01-25 | Adeza Biomedical Corporation | Reagents and kits for determination of fetal fibronectin in a vaginal sample |
| DE3836348A1 (de) * | 1988-10-25 | 1990-04-26 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung von fuer ein antigen klassenspezifischen antikoerpern und dazu geeignetes reagenz |
| ATE135821T1 (de) * | 1989-10-23 | 1996-04-15 | Univ California | Verfahren, das gemischte immunoglobuline verwendet, zum nachweis von rheumatischen faktoren |
| ATE196163T1 (de) | 1990-10-04 | 2000-09-15 | Res Corp Technologies Inc | Varicella-zoster virusantigen |
| US5824319A (en) * | 1990-10-04 | 1998-10-20 | Research Corporation Technologies, Inc. | Varicella-zoster virus antigen |
| US5637632A (en) * | 1992-12-28 | 1997-06-10 | E. I. Du Pont De Nemours And Company | Fire-resistant polyamide resin composition |
| GB9511586D0 (en) * | 1995-06-08 | 1995-08-02 | Tepnel Medical Ltd | Immunological determinations |
| PT863981E (pt) * | 1996-08-01 | 2010-01-04 | Dale Wallis | Detecção, prevenção e tratamento de dermatite digital papilomatosa |
| US8153367B2 (en) * | 1999-10-29 | 2012-04-10 | Perkinelmer Las, Inc. | Amplified array analysis system |
| US20020172980A1 (en) * | 2000-11-27 | 2002-11-21 | Phan Brigitte Chau | Methods for decreasing non-specific binding of beads in dual bead assays including related optical biodiscs and disc drive systems |
| US20040248093A1 (en) * | 2000-11-27 | 2004-12-09 | Coombs James Howard | Magneto-optical bio-discs and systems including related methods |
| US20030003464A1 (en) * | 2000-11-27 | 2003-01-02 | Phan Brigitte C. | Dual bead assays including optical biodiscs and methods relating thereto |
| US6844195B2 (en) * | 2000-12-01 | 2005-01-18 | Western Research Company | Method for determining location of gastrointestinal bleeding |
| AU2004243690A1 (en) * | 2003-03-03 | 2004-12-09 | Burstein Technologies, Inc. | Methods and apparatus for use in detection and quantitation of various cell types and use of optical bio-disc for performing same |
| FR3004184B1 (fr) | 2013-02-26 | 2016-03-18 | Agronomique Inst Nat Rech | Anticorps anti-gluten desamide et utilisations. |
| CN110133268A (zh) * | 2019-05-20 | 2019-08-16 | 北京组学生物科技有限公司 | 针对ap25的elisa试剂盒及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3553310A (en) * | 1967-12-28 | 1971-01-05 | Miles Lab | Immunologically reactive particles |
| USRE29169E (en) * | 1971-02-10 | 1977-04-05 | Akzona Incorporated | Process for the demonstration and determination of reaction components having specific binding affinity for each other |
| NL154599B (nl) * | 1970-12-28 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking. |
| US4016043A (en) * | 1975-09-04 | 1977-04-05 | Akzona Incorporated | Enzymatic immunological method for the determination of antigens and antibodies |
| US4021534A (en) * | 1975-12-12 | 1977-05-03 | Hoffmann-La Roche Inc. | Radioimmunoassay |
| GB1572220A (en) * | 1976-10-07 | 1980-07-30 | Mochida Pharm Co Ltd | Immunochemical process of measuring physiologically active substances |
| DE2733380A1 (de) | 1977-07-23 | 1979-02-08 | Behringwerke Ag | Immunologisches analysenverfahren |
| US4178360A (en) * | 1978-03-15 | 1979-12-11 | Hoffmann-La Roche Inc. | Radiolabelled rubella virus and method |
| US4273756A (en) * | 1978-07-28 | 1981-06-16 | Abbott Laboratories | Immunoassay for class specific antibodies |
| US4292403A (en) * | 1978-08-24 | 1981-09-29 | Akzona Incorporated | Detection and/or determination of IgM, IgA, IgD and IgE immunoglobulins |
| EP0008473B1 (en) * | 1978-08-24 | 1983-06-01 | Akzo N.V. | Method for the detection and/or determination of an antigen specific immunoglobulin, immuno-reagents to be used in said method and test kit for said determination |
| DE2840847A1 (de) * | 1978-09-20 | 1980-04-03 | Behringwerke Ag | Verfahren zum nachweis und zur bestimmung komplementbindender antikoerper |
| US4299812A (en) * | 1978-11-29 | 1981-11-10 | Diagnostic Products Corp. | Immunoassay of thyroxine in neonates using dried blood samples |
-
1979
- 1979-07-28 DE DE19792930706 patent/DE2930706A1/de not_active Withdrawn
-
1980
- 1980-07-02 US US06/165,395 patent/US4347311A/en not_active Expired - Lifetime
- 1980-07-18 AT AT80104220T patent/ATE5747T1/de not_active IP Right Cessation
- 1980-07-18 DE DE8080104220T patent/DE3065997D1/de not_active Expired
- 1980-07-18 EP EP80104220A patent/EP0023989B1/de not_active Expired
- 1980-07-22 JP JP10042280A patent/JPS5621065A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| EP0023989B1 (de) | 1983-12-28 |
| ATE5747T1 (de) | 1984-01-15 |
| DE3065997D1 (en) | 1984-02-02 |
| US4347311A (en) | 1982-08-31 |
| EP0023989A1 (de) | 1981-02-18 |
| JPS5621065A (en) | 1981-02-27 |
| JPS632348B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1988-01-18 |
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