DE2922671C2 - Dental care and cleaning products - Google Patents

Dental care and cleaning products

Info

Publication number
DE2922671C2
DE2922671C2 DE19792922671 DE2922671A DE2922671C2 DE 2922671 C2 DE2922671 C2 DE 2922671C2 DE 19792922671 DE19792922671 DE 19792922671 DE 2922671 A DE2922671 A DE 2922671A DE 2922671 C2 DE2922671 C2 DE 2922671C2
Authority
DE
Germany
Prior art keywords
dental care
substances
cleaning
chewing
cleaning products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE19792922671
Other languages
German (de)
Other versions
DE2922671A1 (en
Inventor
Heinz-Joachim Dr. 6231 Schwalbach Kinkel
Erich 6382 Friedrichsdorf Robens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Battelle Institut eV
Original Assignee
Battelle Institut eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battelle Institut eV filed Critical Battelle Institut eV
Priority to DE19792922671 priority Critical patent/DE2922671C2/en
Publication of DE2922671A1 publication Critical patent/DE2922671A1/en
Application granted granted Critical
Publication of DE2922671C2 publication Critical patent/DE2922671C2/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/26—Aluminium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)

Description

Die Erfindung betrifft ein Zahnpflege- und Zahnreinigungsmittel in Form einer Kaumasse bestehend aus einer kaubaren Matrix und üblichen Zusatzstoffen.The invention relates to a dental care and cleaning agent in the form of a chewing mass consisting of a chewable matrix and usual additives.

Die Entstehung der Zahnkaries und der marginalen Parodontopathien steht in Zusammenhang zur dentogingivalen Plaque. Die Plaque ist eine sich ständig erneuernde Anhäufung von Speichelbestandteilen und vor allem oralen Mikroorganismen. Durch den mikrobiellen Abbau von Zucker aus der Nahrung entstehen Gärungssäuren, die den Zahn lokal entmineralisieren und die kariöse Zerstörung einleiten. Zur vorbeugenden Behandlung der Zähne ist eine regelmäßige und gründliche Reinigung erforderlich. Hierfür werden manuelle und elektrische Zahnbürsten, Zahnstocher, Zahnseide sowie Kausubstanzen herangezogen. Die Zahnbürsten erreichen jedoch selten die wesentlichen Kariesdispositionsstellen. Die bisher bekannten Kaumassen bestehen aus einer Matrix, kariesprophylaktischen Verbindungen, z. B. Fluoriden, und üblichen Zusatzstoffen, z. B. Geschmack- und Aromastoffen. Solche Zusammensetzungen haben jedoch keine ausreichende Reinigungswirkung.The development of dental caries and marginal periodontal disease is related to the dentogingival Plaque. The plaque is a constantly renewing accumulation of saliva components and especially oral microorganisms. Formed by the microbial breakdown of sugar from food Fermentation acids that locally demineralize the tooth and initiate carious destruction. For preventive Treatment of the teeth requires regular and thorough cleaning. For this will be manual and electric toothbrushes, toothpicks, dental floss and chewing substances are used. the Toothbrushes, however, rarely reach the essential caries disposition points. The previously known chewing dimensions consist of a matrix, caries prophylactic compounds, e.g. B. fluorides, and usual Additives, e.g. B. Flavors and aromas. However, such compositions are not sufficient Cleaning effect.

Es ist bekannt, in Kaugummimassen antiseptisch wirksame Stoffe und Arzneimittel einzuarbeiten (DE-OS 29 22 671 und FR-PS 23 20 083). Solche Kaumassen zeigen jedoch keine Reinigungswirkung und eignen sich lediglich zur Sterilisation der Mundhöhle und des Rachens.It is known to incorporate antiseptically active substances and drugs into chewing gum compositions (DE-OS 29 22 671 and FR-PS 23 20 083). However, such gums do not show any cleaning effect and are only suitable for sterilizing the oral cavity and throat.

Der vorliegenden Erfindung liegt daher die Aufgabe zugrunde, eine Kaumasse mit zahnschützender Wirkung zu entwickeln, die bei regelmäßigem Gebrauch auch die Erfordernisse der täglichen Mundhygiene erfüllt.The present invention is therefore based on the object of providing a chewing compound with a tooth-protecting effect to develop that, with regular use, also meets the requirements of daily oral hygiene.

Es hat sich nun gezeigt, daß diese Aufgabe in technisch fortschrittlicher Weise gelöst werden kann, wenn die Kaumasse außer üblichen Zusatzstoffen reinigende Reibmittelteilchen mit einer Teilchengröße von G.l bis 100 μηι und kariesprophylaktische Substanzen enthält. Die vorteilhaften Weiterbildungen des erfindungsgcmäßen Zahnreinigungsmittels sind in den Unteransprüchen 2 und 3 beschrieben.It has now been shown that this problem can be solved in a technically advanced manner, if the chewing mass contains, in addition to the usual additives, cleaning abrasive particles with a particle size from G.l to 100 μm and caries prophylactic substances contains. The advantageous developments of the tooth cleaning agent according to the invention are in the Subclaims 2 and 3 described.

Als kaubare Matrix werden die an sich bekannten Substanzen herangezogen, z. B. hochmolekulare, natürliche oder künstliche Harze und Wachse, Kautschuk, Piccolyt-Harz, Hartparaffine, Bienenwachs, Wollfett, Carnaubawachs, Walrat und Candeliilawachs. Bei den üblichen Zusatzstoffen handelt es sich im wesentlichen um Geschmack- und Aromastoffe. Als Geschmackstoffe können Zuckeraustauschstoffe, wie Sorbit, unc" Süßstoffe, wie Saccharin, verwendet werden. Als Aromastoffe sind z. B. Pfefferminzöl, Spearmintöl, Anisol, Eucalyptusöl, Gewürznelköl, Vanillearoma und Zimtaroma geeignet.The substances known per se are used as the chewable matrix, e.g. B. high molecular weight, natural or artificial resins and waxes, rubber, piccolyte resin, hard paraffins, beeswax, wool fat, Carnauba wax, whale rat and candeliila wax. The usual additives are essentially about flavors and aromas. Sugar substitutes such as sorbitol, unc "sweeteners, such as saccharin, can be used. As flavorings are z. B. peppermint oil, spearmint oil, anisole, eucalyptus oil, Clove oil, vanilla flavor and cinnamon flavor are suitable.

Das erfindungsgemäße Zahnreinigungsmittel enthält von 0,1 bis 20 Gew.-% anorganische und/oder organisehe Reibmittelteilchen. Die anorganischen ReibmittelteiJchen können aus Calciumcarbonat, Dicalciumphosphat, Tricalciumphosphat, Calciumpyrophosphal, CaI-ciumacetat. Calciumsulfat, Aluminiumhydroxid, Aluminiumoxid, Magnesiumoxid, Magnesiumhydroxid, Magnesiumtrisilicat, Magnesiumcarbonat, Magnesiumpyrophosphat und Siliciumdioxid bestehen. Als organische Reibmittelteilchen können unverdauliche Polysaccaride, insbesondere gemahlene, cellulosehaltige Gerüstbestandteile aus Getreidekörnern verwendet werden.The tooth cleaning agent according to the invention contains from 0.1 to 20% by weight of inorganic and / or organic substances Friction agent particles. The inorganic friction particles can be made from calcium carbonate, dicalcium phosphate, Tricalcium phosphate, calcium pyrophosphate, calcium acetate. Calcium sulfate, aluminum hydroxide, aluminum oxide, magnesium oxide, magnesium hydroxide, magnesium trisilicate, Magnesium carbonate, magnesium pyrophosphate and silicon dioxide are made up. As organic Friction agent particles can be indigestible polysaccharides, in particular ground, cellulose-containing structural components made from cereal grains.

Diese Reibmittelteilchen bewirken bei der Kaubewegung eine mechanische Reinigung des Zahnes, können aber auch durch Auflösung im Speichel zahnprophylaktisch wirken. Als kariesprophylaktische Substanzen sind z. B. lösliche Calciumphosphate wie Dicalciumphosphat, Fluoride wie Zinnfluorid, Aminfluorid, Dinatriummonofluorophosphat, Harnstoff, Pepsin, Pankreatin, Papain und Lipasi. geeignet. Vorteilhaft sind vor allem lösliche Calciumphosphate, insbesondere das Dicalciumphosphat, prophylaktischen Zusätze weisen zunächst eineThese abrasive particles cause mechanical cleaning of the tooth during the chewing movement but also have a prophylactic effect on teeth by dissolving in the saliva. As caries prophylactic substances are z. B. soluble calcium phosphates such as dicalcium phosphate, fluorides such as tin fluoride, amine fluoride, disodium monofluorophosphate, Urea, pepsin, pancreatin, papain and lipasi. suitable. Soluble ones are particularly advantageous Calcium phosphates, especially dicalcium phosphate, prophylactic additives initially have a

Scheuerwirkung auf. Nach ihrer Auflösung im Speichel während der üblichen durchschnittlichen Kauzeit von etwa 10 Minuten wirken sie karieshemmend (H. R. Mühlemann, Schweizerische medizinische Wochenschrift 91, 1961, 8, 221-224; H. W. Cremer, W. Büttner, Ernährungsumschau, 9,68 - 72,1962).Abrasive effect. After their dissolution in saliva during the usual average chewing time of They have a caries-inhibiting effect for about 10 minutes (H. R. Mühlemann, Swiss Medical Weekly 91, 1961, 8, 221-224; H. W. Cremer, W. Büttner, Ernahrungumschau, 9.68-72.1962).

Die Reinigungswirkung der Reibmittelteilchen kann unterstützt werden durch Verwendung von verträglichen Tensiden, wie Natriumlaurylsulfat, Dinatriumoctylsulfosuccinat, Natriumkylsulfoacetat, Natrjumlaurylsarkosinat, Sorbitanester, Diammoniumphosphat, Borax, Glykokoll, sowie enzymatisch wirkende Reinigungsmittel. The cleaning effect of the friction agent particles can be enhanced by using compatible Surfactants, such as sodium lauryl sulfate, disodium octyl sulfosuccinate, sodium alkyl sulfoacetate, sodium lauryl sarcosinate, Sorbitan ester, diammonium phosphate, borax, glycocolla and enzymatic cleaning agents.

Die Herstellung des erfindungsgemäßen Zahnreinigungsmittels kann in an sich bekannter Weise erfolgen.The tooth cleaning agent according to the invention can be produced in a manner known per se.

Beispielsweise werden die Bestandteile in gelöster Form vermischt und die Lösungsmittel anschließend verdampft. Ferner können pulverförmige Bestandteile durch Kneten der Kaumasse einverleibt werden.For example, the components are mixed in dissolved form and the solvents are then evaporated. Powdered ingredients can also be incorporated by kneading the chewing mass.

Claims (3)

Patentansprüche:Patent claims: 1. Zahnpflege- und Zahnreinigungsmittel in Form einer Kaumasse, bestehend aus einer kaubaren Matrix und üblichen Zusatzstoffen, dadurch gekennzeichnet, daß es reinigende Reibmittelteilchen mit einer Teilchengröße von 0,1 bis 100 μΐη und kariesprophylaktische Substanzen enthält 1. Dental care and cleaning agents in the form of a chewing compound, consisting of a chewable one Matrix and customary additives, characterized in that it contains cleaning abrasive particles with a particle size of 0.1 to 100 μΐη and contains caries prophylactic substances 2. Zahnpflege- und Zahnreinigungsmittel nach Anspruch 1, dadurch gekennzeichnet, daß es oberflächenaktive Stoffe enthält2. Dental care and tooth cleaning agent according to claim 1, characterized in that it is surface-active Contains substances 3. Zahnpflege- und Zahnreinigungsmittel nach Anspruch 1 oder 2, dadurch gekennzeichnet, daß die Reibmittelteilchen aus anorganischen und/oder organischen Substanzen bestehen und in einer Menge von 0,1 bis 20Gew.-% bezogen auf das Gesamtgewicht enthalten sind.3. Dental care and tooth cleaning agent according to claim 1 or 2, characterized in that the Friction agent particles consist of inorganic and / or organic substances and in one Amounts from 0.1 to 20% by weight based on the total weight are included.
DE19792922671 1979-06-02 1979-06-02 Dental care and cleaning products Expired DE2922671C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19792922671 DE2922671C2 (en) 1979-06-02 1979-06-02 Dental care and cleaning products

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792922671 DE2922671C2 (en) 1979-06-02 1979-06-02 Dental care and cleaning products

Publications (2)

Publication Number Publication Date
DE2922671A1 DE2922671A1 (en) 1980-12-04
DE2922671C2 true DE2922671C2 (en) 1982-08-19

Family

ID=6072439

Family Applications (1)

Application Number Title Priority Date Filing Date
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Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2922671C2 (en) 1979-06-02 1982-08-19 Battelle-Institut E.V., 6000 Frankfurt Dental care and cleaning products
US4446135A (en) * 1982-06-07 1984-05-01 Sterling Drug Inc. Chewable antacid tablets
US4915936A (en) * 1988-10-31 1990-04-10 United States Gypsum Company Dental hygiene composition for reducing periodontal disease
US5066335A (en) * 1989-05-02 1991-11-19 Ogilvie Mills Ltd. Glass-like polysaccharide abrasive grit
US5013728A (en) * 1990-05-04 1991-05-07 Colgate - Palmolive Company Composition for treating osteoporosis and hormonal imbalance
GB9412048D0 (en) * 1994-06-16 1994-08-03 Boots Co Plc Oral hygiene composition
US6159257A (en) * 1998-10-21 2000-12-12 Adm Agri-Industries, Ltd. Water-resistant, glass-like, polysaccharide abrasive grits and method of making same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2320083A1 (en) * 1975-08-07 1977-03-04 Sigma Tau Ind Farmaceuti Medicated chewing gum - contg. e.g. cetylpyridinium chloride as antiseptic and pref. guaiazulene decongestant
DE2922671C2 (en) 1979-06-02 1982-08-19 Battelle-Institut E.V., 6000 Frankfurt Dental care and cleaning products

Also Published As

Publication number Publication date
DE2922671A1 (en) 1980-12-04

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