DE2830442A1 - Verfahren zur herstellung von polypeptiden - Google Patents

Verfahren zur herstellung von polypeptiden

Info

Publication number
DE2830442A1
DE2830442A1 DE19782830442 DE2830442A DE2830442A1 DE 2830442 A1 DE2830442 A1 DE 2830442A1 DE 19782830442 DE19782830442 DE 19782830442 DE 2830442 A DE2830442 A DE 2830442A DE 2830442 A1 DE2830442 A1 DE 2830442A1
Authority
DE
Germany
Prior art keywords
cys
lys
ile
peptide
ddz
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19782830442
Other languages
German (de)
English (en)
Other versions
DE2830442C2 (enExample
Inventor
Christian Dr Birr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ORPEGEN MEDIZINISCH-MOLEKULARBIOLOGISCHE FORSCHUNG
Original Assignee
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft zur Foerderung der Wissenschaften eV filed Critical Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Priority to DE19782830442 priority Critical patent/DE2830442A1/de
Priority to CH309879A priority patent/CH637629A5/de
Priority to US06/039,979 priority patent/US4290943A/en
Publication of DE2830442A1 publication Critical patent/DE2830442A1/de
Application granted granted Critical
Publication of DE2830442C2 publication Critical patent/DE2830442C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
DE19782830442 1978-07-11 1978-07-11 Verfahren zur herstellung von polypeptiden Granted DE2830442A1 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE19782830442 DE2830442A1 (de) 1978-07-11 1978-07-11 Verfahren zur herstellung von polypeptiden
CH309879A CH637629A5 (de) 1978-07-11 1979-04-03 Verfahren zur herstellung von polypeptiden.
US06/039,979 US4290943A (en) 1978-07-11 1979-05-17 Method of preparing polypeptides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782830442 DE2830442A1 (de) 1978-07-11 1978-07-11 Verfahren zur herstellung von polypeptiden

Publications (2)

Publication Number Publication Date
DE2830442A1 true DE2830442A1 (de) 1980-01-24
DE2830442C2 DE2830442C2 (enExample) 1992-07-09

Family

ID=6044088

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782830442 Granted DE2830442A1 (de) 1978-07-11 1978-07-11 Verfahren zur herstellung von polypeptiden

Country Status (3)

Country Link
US (1) US4290943A (enExample)
CH (1) CH637629A5 (enExample)
DE (1) DE2830442A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2919592A1 (de) * 1979-05-15 1981-01-15 Max Planck Gesellschaft Verfahren zur herstellung von thymosin- alpha 1 und derivaten davon
EP0085250A3 (en) * 1982-01-21 1983-09-14 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
EP0102483A1 (en) * 1982-09-02 1984-03-14 Sirac Srl Process for preparing alpha-l-aspartyl-l-phenylalanine alkyl esters
US6107459A (en) * 1991-02-08 2000-08-22 Diatide, Inc. Technetium-99m labeled peptides for diagnostic imaging

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2187461A (en) * 1986-02-03 1987-09-09 Medical Res Council Monitoring method for the synthesis of a linear of amino acid residues
US6407059B1 (en) * 1994-06-08 2002-06-18 Peptor Limited Conformationally constrained backbone cyclized peptide analogs
AU2003207940A1 (en) * 2002-01-03 2003-07-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem Conformationally constrained c-backbone cyclic peptides
DK1644401T3 (da) * 2003-07-04 2011-06-20 Lonza Ag Forbedret fremgangsmåde til fastfasesyntese

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028315A (en) * 1970-10-16 1977-06-07 E. R. Squibb & Sons, Inc. Solid phase synthesis of peptides
US3715190A (en) * 1971-09-23 1973-02-06 Univ Sherbrooke System for the solid-phase peptide synthesis
SE399880B (sv) * 1973-05-24 1978-03-06 Ciba Geigy Ag Sett att framstella peptider, som innehaller mer en en disulfidbindning
US4062746A (en) * 1975-05-07 1977-12-13 Wisconsin Alumni Research Foundation Solid phase synthesis of protected peptides
US4093609A (en) * 1976-12-10 1978-06-06 American Home Products Corporation Somatostatin synthesis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GOODMAN, M., MEIENHOFER, J.: Peptides, 1977, S.iii, xi, 510-513 *
HOUBEN-WEYL, Methoden der org. Chemie, 4. Aufl., 1974, Bd. XV/1, S. 347,374-376 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2919592A1 (de) * 1979-05-15 1981-01-15 Max Planck Gesellschaft Verfahren zur herstellung von thymosin- alpha 1 und derivaten davon
EP0085250A3 (en) * 1982-01-21 1983-09-14 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
EP0102483A1 (en) * 1982-09-02 1984-03-14 Sirac Srl Process for preparing alpha-l-aspartyl-l-phenylalanine alkyl esters
US6107459A (en) * 1991-02-08 2000-08-22 Diatide, Inc. Technetium-99m labeled peptides for diagnostic imaging

Also Published As

Publication number Publication date
US4290943A (en) 1981-09-22
CH637629A5 (de) 1983-08-15
DE2830442C2 (enExample) 1992-07-09

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: BIRR, CHRISTIAN, PROF. DR., 6900 HEIDELBERG, DE

8127 New person/name/address of the applicant

Owner name: ORGANOGEN MEDIZINISCH-MOLEKULARBIOLOGISCHE FORSCHU

8110 Request for examination paragraph 44
8127 New person/name/address of the applicant

Owner name: ORPEGEN MEDIZINISCH-MOLEKULARBIOLOGISCHE FORSCHUNG

D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee