DE2630638A1 - Chemische verbindung und ein eine derartige verbindung enthaltendes medikament gegen entzuendungen - Google Patents
Chemische verbindung und ein eine derartige verbindung enthaltendes medikament gegen entzuendungenInfo
- Publication number
- DE2630638A1 DE2630638A1 DE19762630638 DE2630638A DE2630638A1 DE 2630638 A1 DE2630638 A1 DE 2630638A1 DE 19762630638 DE19762630638 DE 19762630638 DE 2630638 A DE2630638 A DE 2630638A DE 2630638 A1 DE2630638 A1 DE 2630638A1
- Authority
- DE
- Germany
- Prior art keywords
- compound
- medicine containing
- chemical
- peroxides
- inflammation medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000001875 compounds Chemical class 0.000 title claims description 12
- 206010061218 Inflammation Diseases 0.000 title description 4
- 230000004054 inflammatory process Effects 0.000 title description 4
- 239000003814 drug Substances 0.000 claims description 12
- 150000002978 peroxides Chemical class 0.000 claims description 11
- 150000001299 aldehydes Chemical class 0.000 claims description 7
- 229940093429 polyethylene glycol 6000 Drugs 0.000 claims description 6
- LCPVQAHEFVXVKT-UHFFFAOYSA-N 2-(2,4-difluorophenoxy)pyridin-3-amine Chemical compound NC1=CC=CN=C1OC1=CC=C(F)C=C1F LCPVQAHEFVXVKT-UHFFFAOYSA-N 0.000 claims description 4
- 102000003992 Peroxidases Human genes 0.000 claims description 4
- CHQMHPLRPQMAMX-UHFFFAOYSA-L sodium persulfate Substances [Na+].[Na+].[O-]S(=O)(=O)OOS([O-])(=O)=O CHQMHPLRPQMAMX-UHFFFAOYSA-L 0.000 claims description 4
- HFFLGKNGCAIQMO-UHFFFAOYSA-N trichloroacetaldehyde Chemical compound ClC(Cl)(Cl)C=O HFFLGKNGCAIQMO-UHFFFAOYSA-N 0.000 claims description 4
- 239000002260 anti-inflammatory agent Substances 0.000 claims description 3
- 108040007629 peroxidase activity proteins Proteins 0.000 claims description 3
- 239000000126 substance Substances 0.000 claims description 3
- 229940124599 anti-inflammatory drug Drugs 0.000 claims description 2
- 229910052736 halogen Inorganic materials 0.000 claims description 2
- 150000002367 halogens Chemical class 0.000 claims description 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 6
- 206010028980 Neoplasm Diseases 0.000 description 5
- 201000011510 cancer Diseases 0.000 description 4
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 3
- 201000004624 Dermatitis Diseases 0.000 description 2
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- COHYTHOBJLSHDF-UHFFFAOYSA-N Indigo Chemical compound N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 description 2
- 208000038016 acute inflammation Diseases 0.000 description 2
- 230000006022 acute inflammation Effects 0.000 description 2
- 230000032683 aging Effects 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 206010003246 arthritis Diseases 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 208000037976 chronic inflammation Diseases 0.000 description 2
- 230000006020 chronic inflammation Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000002757 inflammatory effect Effects 0.000 description 2
- 150000001451 organic peroxides Chemical class 0.000 description 2
- 201000008482 osteoarthritis Diseases 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 200000000007 Arterial disease Diseases 0.000 description 1
- 206010005949 Bone cancer Diseases 0.000 description 1
- 208000018084 Bone neoplasm Diseases 0.000 description 1
- 208000003174 Brain Neoplasms Diseases 0.000 description 1
- 241000698776 Duma Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 206010061216 Infarction Diseases 0.000 description 1
- 108700020962 Peroxidase Proteins 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- RDYMFSUJUZBWLH-UHFFFAOYSA-N endosulfan Chemical compound C12COS(=O)OCC2C2(Cl)C(Cl)=C(Cl)C1(Cl)C2(Cl)Cl RDYMFSUJUZBWLH-UHFFFAOYSA-N 0.000 description 1
- 208000005017 glioblastoma Diseases 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000007574 infarction Effects 0.000 description 1
- ICIWUVCWSCSTAQ-UHFFFAOYSA-M iodate Chemical compound [O-]I(=O)=O ICIWUVCWSCSTAQ-UHFFFAOYSA-M 0.000 description 1
- 210000003712 lysosome Anatomy 0.000 description 1
- 230000001868 lysosomic effect Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 description 1
- 229960002216 methylparaben Drugs 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 125000004430 oxygen atom Chemical group O* 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- KHIWWQKSHDUIBK-UHFFFAOYSA-N periodic acid Chemical compound OI(=O)(=O)=O KHIWWQKSHDUIBK-UHFFFAOYSA-N 0.000 description 1
- 238000005502 peroxidation Methods 0.000 description 1
- JRKICGRDRMAZLK-UHFFFAOYSA-L peroxydisulfate Chemical compound [O-]S(=O)(=O)OOS([O-])(=O)=O JRKICGRDRMAZLK-UHFFFAOYSA-L 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 210000000278 spinal cord Anatomy 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/77—Polymers containing oxygen of oxiranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/40—Peroxides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7521280A FR2316923A1 (fr) | 1975-07-07 | 1975-07-07 | Composition et medicament anti-inflammatoire qui comprend une telle composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2630638A1 true DE2630638A1 (de) | 1977-01-27 |
Family
ID=9157609
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19762630638 Ceased DE2630638A1 (de) | 1975-07-07 | 1976-07-07 | Chemische verbindung und ein eine derartige verbindung enthaltendes medikament gegen entzuendungen |
Country Status (3)
| Country | Link |
|---|---|
| BE (2) | BE843831A (https=) |
| DE (1) | DE2630638A1 (https=) |
| FR (1) | FR2316923A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4137544A1 (de) * | 1991-11-12 | 1993-05-13 | Hepper Martin | Antimikrobielle wirkstoffkombination auf der basis von sauerstoff abspaltenden verbindungen |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4201858A1 (de) * | 1992-01-24 | 1993-07-29 | Renschler Aloys Dr Med | Mittel zur behandlung maligner zellen |
| GB2421908A (en) * | 2004-12-23 | 2006-07-12 | Univ College London Hospitals | Medicament for treatment of inflammatory diseases |
-
0
- BE BE0/203658A patent/BE887320A/fr not_active IP Right Cessation
-
1975
- 1975-07-07 FR FR7521280A patent/FR2316923A1/fr active Granted
-
1976
- 1976-07-06 BE BE168673A patent/BE843831A/xx not_active IP Right Cessation
- 1976-07-07 DE DE19762630638 patent/DE2630638A1/de not_active Ceased
Non-Patent Citations (3)
| Title |
|---|
| Hager: Handbuch der Pharmazeutischen Praxis, 1977, S. 122 * |
| Martindale: The Extra Pharmacopoeia, 26. Ed., S. 743-745 * |
| Negwer, M.: Org.chem. Arzneimittel und ihre Synonyma, 1971, S. 7, Nr. 32 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4137544A1 (de) * | 1991-11-12 | 1993-05-13 | Hepper Martin | Antimikrobielle wirkstoffkombination auf der basis von sauerstoff abspaltenden verbindungen |
| DE4137544C2 (de) * | 1991-11-12 | 1998-07-30 | Kramer Axel | Antimikrobielle Wirkstoffkombination auf der Basis von Sauerstoff abspaltenden Verbindungen |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2316923B1 (https=) | 1978-07-28 |
| BE843831A (fr) | 1976-11-03 |
| BE887320A (fr) | 1981-05-14 |
| FR2316923A1 (fr) | 1977-02-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3032462A1 (de) | Praeparate zur anwendung an oder in geweben und/oder fluessigkeiten des menschlichen oder tierischen koerpers | |
| CH638981A5 (de) | Topisches therapeutisches mittel zur behandlung von akne vulgaris. | |
| CH662945A5 (de) | Ophthalmische loesung. | |
| DE2947742C2 (de) | Arzneimittel, enthaltend β-Cyclodextrin | |
| DE3302739A1 (de) | Oxidationsstabiles mittel | |
| Broman et al. | Experimental comparison of diodonum with sodium acetrizoate with reference to possible injurious effects on the blood-brain barrier | |
| DE69229780T2 (de) | Zusammensetzung und methode zur behandlung von störungen in form von depigmentierung | |
| DE69111974T2 (de) | Verwendung von Lithium zur Behandlung oder Prophylaxe von Molluscum contagiusum. | |
| DE3828044A1 (de) | Silbersulfadiazinhaltiges mittel zur lokalen aeusserlichen therapie von herpes labialis, herpes genitalis, herpes corporis, zoster (herpes zoster, windpocken sowie ekzema herpeticatum und verbrennungen 11. und 111. grades im bereich der humanmedizin | |
| DE1804801C3 (de) | Mittel zur Aknebehandlung | |
| CH634481A5 (de) | Dithranol enthaltendes mittel zur behandlung von psoriasis. | |
| DE2630638A1 (de) | Chemische verbindung und ein eine derartige verbindung enthaltendes medikament gegen entzuendungen | |
| EP1196159A1 (de) | Verwendung von tosylchloramid(en) zur behandlung von erkrankungen der haut, der schleimhaut, von organen und geweben | |
| WO1994011009A1 (de) | Zusammensetzung zur bekämpfung von dermatomykosen und deren erregern sowie von schweissbildung und körpergeruch | |
| DE68915154T2 (de) | Anwendung von gegen retroviren aktiven wirkstoffen und so erhaltene produkte. | |
| DE3590001T1 (de) | Arzneimittel zur oralen Verabreichung für die Behandlung oder Verhinderung von Akne | |
| DE1961146A1 (de) | Mittel fuer die physiologische Behandlung der Haut | |
| DE3438005A1 (de) | Pharmazeutisches mittel zur lokalen therapie der psoriasis | |
| DE19953517C1 (de) | Verwendung von Treosulfan zur Konditionierung von Patienten vor Knochemarktransplantation oder Blutstammzelltransplantation | |
| DE69231968T2 (de) | Behandlung eines durch uv-strahlung verursachten erythems | |
| DE69936773T2 (de) | Behandlung von depression und zusammensetzungen dazu | |
| WO1997006769A2 (de) | Pharmazeutisches präparat mit trypanoziden eigenschaften enthaltend diminazen, pentamidin und phenazon | |
| DE2041831C3 (de) | alpha-Amino-beta-(N-Benzylthiocarbamoyl)-thiopropionsäure, Verfahren zu ihrer Herstellung, sowie diese enthaltende Arzneimittel | |
| DE69716769T2 (de) | Zubereitungen zur behandlung von verbrennungen und externen ulcera sowie verfahren zu deren herstellung | |
| DE3911263C2 (https=) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8110 | Request for examination paragraph 44 | ||
| 8131 | Rejection |