DE2531257C2 - Verfahren zur Herstellung von 8,2'-Anhydropurinnucleosiden - Google Patents

Verfahren zur Herstellung von 8,2'-Anhydropurinnucleosiden

Info

Publication number
DE2531257C2
DE2531257C2 DE2531257A DE2531257A DE2531257C2 DE 2531257 C2 DE2531257 C2 DE 2531257C2 DE 2531257 A DE2531257 A DE 2531257A DE 2531257 A DE2531257 A DE 2531257A DE 2531257 C2 DE2531257 C2 DE 2531257C2
Authority
DE
Germany
Prior art keywords
mmol
acid
nucleosides
sodium
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2531257A
Other languages
German (de)
English (en)
Other versions
DE2531257A1 (de
Inventor
Kunio Fuji Shizuoka Iitsuka
Kiyohide Nobeoka Miyazaki Sako
Tsuneo Nobeoka Miyazaki Sowa
Kozo Tsunoda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Original Assignee
Asahi Kasei Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP8117174A external-priority patent/JPS5111798A/ja
Priority claimed from JP9071674A external-priority patent/JPS5119796A/ja
Application filed by Asahi Kasei Kogyo KK filed Critical Asahi Kasei Kogyo KK
Publication of DE2531257A1 publication Critical patent/DE2531257A1/de
Application granted granted Critical
Publication of DE2531257C2 publication Critical patent/DE2531257C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE2531257A 1974-07-17 1975-07-12 Verfahren zur Herstellung von 8,2'-Anhydropurinnucleosiden Expired DE2531257C2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8117174A JPS5111798A (en) 1974-07-17 1974-07-17 8*2**oo anhidoropurinnukureoshidono seizohoho
JP9071674A JPS5119796A (en) 1974-08-09 1974-08-09 8*2**00 anhidoroadenoshinno seizohoho

Publications (2)

Publication Number Publication Date
DE2531257A1 DE2531257A1 (de) 1976-01-29
DE2531257C2 true DE2531257C2 (de) 1982-12-09

Family

ID=26422209

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2531257A Expired DE2531257C2 (de) 1974-07-17 1975-07-12 Verfahren zur Herstellung von 8,2'-Anhydropurinnucleosiden

Country Status (4)

Country Link
US (1) US4112221A (US06229276-20010508-P00022.png)
CH (1) CH601341A5 (US06229276-20010508-P00022.png)
DE (1) DE2531257C2 (US06229276-20010508-P00022.png)
FR (1) FR2278703A1 (US06229276-20010508-P00022.png)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62501712A (ja) * 1985-08-26 1987-07-09 アメリカ合衆国 ２′、３′―ジデオキシイノシン、２′，３′―ジデオキシグアノシンまたは２′，３′―ジデオキシアデノシンを含有する抗ｈｔｌｖ―３／ｌａｖ剤
US6090932A (en) * 1994-06-22 2000-07-18 Proligo Llc Method of preparation of known and novel 2'-modified nucleosides by intramolecular nucleophilic displacement
WO1998030575A1 (en) 1997-01-08 1998-07-16 Proligo Llc Bioconjugation of macromolecules
US7427678B2 (en) 1998-01-08 2008-09-23 Sigma-Aldrich Co. Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method
WO2003062452A2 (en) 2002-01-23 2003-07-31 Proligo, Llc Methods for the integrated synthesis and purification of oligonucleotides
AU2002361255A1 (en) 2002-12-31 2004-07-22 Proligo Llc Methods and compositions for the tandem synthesis of two or more oligonuleotides on the same solid support

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3322747A (en) * 1965-04-01 1967-05-30 Merck & Co Inc Thionocarbonate nucleosides
US3792040A (en) * 1970-03-19 1974-02-12 Syntex Corp Acyl derivatives of o2,2'-anhydro-1-(beta-d-arabinofuranosyl)-cytosines and methods of preparing
SE391183B (sv) * 1971-04-15 1977-02-07 Asahi Chemical Ind 2',3'-0-sulfinylcytidin och syraadditionssalter derav till anvendning som mellanprodukt for framstellning av 2,2'-anhydro-(1-beta-d-arabinofuranosyl) cytosin

Also Published As

Publication number Publication date
US4112221A (en) 1978-09-05
FR2278703B1 (US06229276-20010508-P00022.png) 1978-11-03
CH601341A5 (US06229276-20010508-P00022.png) 1978-07-14
DE2531257A1 (de) 1976-01-29
FR2278703A1 (fr) 1976-02-13

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Legal Events

Date Code Title Description
D2 Grant after examination
8339 Ceased/non-payment of the annual fee