DE2502119A1 - Modifizierte antibiotica - Google Patents

Modifizierte antibiotica

Info

Publication number
DE2502119A1
DE2502119A1 DE19752502119 DE2502119A DE2502119A1 DE 2502119 A1 DE2502119 A1 DE 2502119A1 DE 19752502119 DE19752502119 DE 19752502119 DE 2502119 A DE2502119 A DE 2502119A DE 2502119 A1 DE2502119 A1 DE 2502119A1
Authority
DE
Germany
Prior art keywords
dihydro
methyl
piperazinyl
mixture
phenyl7
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19752502119
Other languages
German (de)
English (en)
Inventor
Leonard Doub
James Stanley Kaltenbronn
Dieter Schweiss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parke Davis and Co LLC
Original Assignee
Parke Davis and Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parke Davis and Co LLC filed Critical Parke Davis and Co LLC
Publication of DE2502119A1 publication Critical patent/DE2502119A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DE19752502119 1974-01-21 1975-01-20 Modifizierte antibiotica Pending DE2502119A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43476374A 1974-01-21 1974-01-21

Publications (1)

Publication Number Publication Date
DE2502119A1 true DE2502119A1 (de) 1975-07-24

Family

ID=23725581

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752502119 Pending DE2502119A1 (de) 1974-01-21 1975-01-20 Modifizierte antibiotica

Country Status (13)

Country Link
JP (1) JPS50106995A (en, 2012)
AT (1) AT336788B (en, 2012)
AU (1) AU7767675A (en, 2012)
BE (1) BE824579A (en, 2012)
DE (1) DE2502119A1 (en, 2012)
DK (1) DK14975A (en, 2012)
ES (2) ES433981A1 (en, 2012)
FR (1) FR2263764B1 (en, 2012)
GB (1) GB1464525A (en, 2012)
IL (1) IL46478A0 (en, 2012)
NL (1) NL7500645A (en, 2012)
SE (1) SE7500570L (en, 2012)
ZA (1) ZA7546B (en, 2012)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2744170A1 (de) * 1976-10-02 1978-04-06 Meiji Seika Kaisha Cephalosporinderivate und verfahren zu deren herstellung

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4101661A (en) * 1977-06-03 1978-07-18 Warner-Lambert Novel antibacterial amide compounds and process means for producing the same
US4311698A (en) * 1979-03-12 1982-01-19 Haskell Theodore H Aminoacid derivatives of cephalosporin compounds
JPS5651488A (en) * 1979-10-02 1981-05-09 Meiji Seika Kaisha Ltd Penicillin derivative and its preparation
USRE46117E1 (en) 1999-12-22 2016-08-23 Teva Pharmaceuticals International Gmbh Modulators of dopamine neurotransmission
SE9904724D0 (sv) * 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission I
JP2008523075A (ja) * 2004-12-13 2008-07-03 アリーナ ファーマシューティカルズ， インコーポレイテッド ５ｈｔ２ｃレセプター関連障害の処置に有用な５ｈｔ２ｃレセプターのモジュレーターとしてのｎ−ビアリールピペラジン誘導体およびｎ−アリールヘテロアリールピペラジン誘導体
SE529246C2 (sv) 2005-10-13 2007-06-12 Neurosearch Sweden Ab Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission
ES2776678T3 (es) 2012-04-04 2020-07-31 Prilenia Neurotherapeutics Ltd Composiciones farmacéuticas para terapia de combinación

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2744170A1 (de) * 1976-10-02 1978-04-06 Meiji Seika Kaisha Cephalosporinderivate und verfahren zu deren herstellung

Also Published As

Publication number Publication date
ES448721A1 (es) 1977-07-16
BE824579A (fr) 1975-05-15
GB1464525A (en, 2012) 1977-02-16
AT336788B (de) 1977-05-25
DK14975A (en, 2012) 1975-09-22
NL7500645A (nl) 1975-07-23
FR2263764A1 (en, 2012) 1975-10-10
AU7767675A (en) 1976-07-29
IL46478A0 (en) 1975-04-25
ES433981A1 (es) 1977-03-01
ATA36475A (de) 1976-09-15
JPS50106995A (en, 2012) 1975-08-22
ZA7546B (en) 1976-08-25
SE7500570L (en, 2012) 1975-07-22
FR2263764B1 (en, 2012) 1978-07-07

Similar Documents

Publication Publication Date Title
DE69310563T2 (de) Kondensierte Imidazopyridinderivate mit psychotropischer Wirkung
DE3011490C2 (en, 2012)
DE69305344T2 (de) Antianginale purinone
DE69307712T2 (de) Pyridopyrimidinone als wirkstoffe gegen angina
DE69530989T2 (de) Neue pyrimidinderivate und verfahren zu ihrer herstellung
DE69303191T2 (de) Naphthalinderivate, ihre Herstellungsverfahren und synthetische Zwischenprodukte dafür
DE2502119A1 (de) Modifizierte antibiotica
DE2849537A1 (de) Substituierte 5-(2-imidazolin-2-yl)- aminopyrimidine und verfahren zu deren herstellung
DE2505297B2 (de) Verfahren zur Herstellung von in 2- und 6-Stellung des Phenylkerns substituierten 2-Phenylamino-2-imidazolin-Derivaten
EP0126296B1 (de) Substituierte Phenyl-2-(1H)-pyrimidinone, Verfahren zu ihrer Herstellung und ihre Verwendung sowie diese Verbindungen enthaltende Zubereitungen
DE69418218T2 (de) Chinolonylcarboxamidocephalosporin-derivate und diese enthaltende arzneimittel
DE3015389A1 (de) Heterocyclische derivate von oxyimino-substituierten cephalosporinen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische und veterinaermedizinische mittel
DE2222953A1 (de) Verfahren zur herstellung antibakterieller mittel
DE2804949A1 (de) Substituierte tetrazolverbindungen
DE69520345T2 (de) Diphenyl-disulfid Verbindungen
DE69004389T2 (de) Heteroarylsubstituierte Imidazo[4,5-c]pyridine.
DE3038593C2 (en, 2012)
CH665641A5 (de) Acylamino-mitosane.
DE3807084A1 (de) Neue benzimidazo(1,2-c)chinazoline, ihre herstellung und verwendung
US4053470A (en) Substituted-1,2-dihydro-2-oxonicotinyl-cephalosporins
DD220780A5 (de) Verfahren zur herstellung von 5-subst.-(1,2,4) triazolo (1,5-c) pryimidin-2-aminen
DE69427394T2 (de) Kondensierte heterocyclische glutaminsäurederivate als antiproliferative mittel
DE1950990A1 (de) Verfahren zur Herstellung von neuen triazacyclischen Verbindungen
DE2903850A1 (de) 2-amino-8-cyclopropyl-5-oxo-5,8- dihydro-pyrido eckige klammer auf 2,3-d eckige klammer zu -pyrimidin-6-carnonsaeuren, verfahren zu ihrer herstellung sowie ihrer verwendung als antibakterielle mittel
EP0377437B1 (de) Verfahren zur Herstellung von 2,4-Diamino-6-piperidinyl-pyrimidin-3-N-oxid

Legal Events

Date Code Title Description
OHJ Non-payment of the annual fee