DE2443950B2 - Verfahren zur bestimmung des anomalen verhaltens von saeugetier-zellen - Google Patents
Verfahren zur bestimmung des anomalen verhaltens von saeugetier-zellenInfo
- Publication number
- DE2443950B2 DE2443950B2 DE19742443950 DE2443950A DE2443950B2 DE 2443950 B2 DE2443950 B2 DE 2443950B2 DE 19742443950 DE19742443950 DE 19742443950 DE 2443950 A DE2443950 A DE 2443950A DE 2443950 B2 DE2443950 B2 DE 2443950B2
- Authority
- DE
- Germany
- Prior art keywords
- cells
- polarization
- fluorescence
- measured
- excitation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 230000037427 ion transport Effects 0.000 description 1
- 229940057995 liquid paraffin Drugs 0.000 description 1
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- 208000003747 lymphoid leukemia Diseases 0.000 description 1
- 230000036210 malignancy Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- VSQYNPJPULBZKU-UHFFFAOYSA-N mercury xenon Chemical compound [Xe].[Hg] VSQYNPJPULBZKU-UHFFFAOYSA-N 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000000693 micelle Substances 0.000 description 1
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- 230000000717 retained effect Effects 0.000 description 1
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- 230000007306 turnover Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6445—Measuring fluorescence polarisation
Landscapes
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL43224A IL43224A (en) | 1973-09-14 | 1973-09-14 | Fluorescence polarization measurements |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2443950A1 DE2443950A1 (de) | 1975-03-27 |
| DE2443950B2 true DE2443950B2 (de) | 1976-12-02 |
Family
ID=11047351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19742443950 Granted DE2443950B2 (de) | 1973-09-14 | 1974-09-13 | Verfahren zur bestimmung des anomalen verhaltens von saeugetier-zellen |
Country Status (7)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2953524A1 (de) * | 1978-04-20 | 1981-08-06 | Howard Maurice West Newton Mass. Shapiro | Biologisches messverfahren |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL49130A (en) * | 1976-03-02 | 1979-07-25 | Elscint Ltd | Method for rapid diagnosis of fetus maturity |
| IL49622A0 (en) * | 1976-05-21 | 1976-07-30 | Elscint Ltd | A method and apparatus for classifying biological cells |
| IL49776A (en) * | 1976-06-13 | 1979-05-31 | Elscint Ltd | Method and appararus for differentiating of normal and abnormal mammalian cells |
| US4198123A (en) * | 1977-03-23 | 1980-04-15 | Baxter Travenol Laboratories, Inc. | Optical scrambler for depolarizing light |
| JPS55109949A (en) * | 1979-02-16 | 1980-08-23 | Hitachi Ltd | Spectro-fluorophotometer |
| US4419583A (en) * | 1980-05-31 | 1983-12-06 | Noeller Hans Guenter | Polarization fluoroimmunoassay with pulsed light source |
| CA1165585A (en) * | 1981-01-09 | 1984-04-17 | Susan R. Popelka | Optical apparatus for a fluorescence polarization instrument |
| US4640898A (en) * | 1983-08-01 | 1987-02-03 | University Of Health Sciences/The Chicago Medical School | Homogeneous fluorescence ligang binding assay based upon preferential alteration of the respective intensities of bound and free label by solvent components |
| US8192026B2 (en) | 2007-06-20 | 2012-06-05 | Tearscience, Inc. | Tear film measurement |
| US7758190B2 (en) | 2007-06-20 | 2010-07-20 | Tearscience, Inc. | Tear film measurement |
| US9642520B2 (en) | 2009-04-01 | 2017-05-09 | Tearscience, Inc. | Background reduction apparatuses and methods of ocular surface interferometry (OSI) employing polarization for imaging, processing, and/or displaying an ocular tear film |
| US8888286B2 (en) | 2009-04-01 | 2014-11-18 | Tearscience, Inc. | Full-eye illumination ocular surface imaging of an ocular tear film for determining tear film thickness and/or providing ocular topography |
| US9888839B2 (en) | 2009-04-01 | 2018-02-13 | Tearscience, Inc. | Methods and apparatuses for determining contact lens intolerance in contact lens wearer patients based on dry eye tear film characteristic analysis and dry eye symptoms |
| WO2010115008A1 (en) | 2009-04-01 | 2010-10-07 | Tearscience, Inc. | Ocular surface interferometry (osi) devices, systems, and methods for imaging, processing, and/or displaying an ocular tear film and/or measuring ocular tear film layer thickness (es) |
| US8915592B2 (en) | 2009-04-01 | 2014-12-23 | Tearscience, Inc. | Apparatuses and methods of ocular surface interferometry (OSI) employing polarization and subtraction for imaging, processing, and/or displaying an ocular tear film |
| DE102009031194A1 (de) * | 2009-06-29 | 2010-12-30 | Evgeny Pavlovich Germanov Et Al | Verfahren und Einrichtung zur Bestimmung der Malignität von Zell-und Gewebestrukturen(-gefügen) und des Grads der Isotropie (Symmetrie) von biologischem Material (Objekt) |
| US9339177B2 (en) | 2012-12-21 | 2016-05-17 | Tearscience, Inc. | Full-eye illumination ocular surface imaging of an ocular tear film for determining tear film thickness and/or providing ocular topography |
| CA2911294C (en) | 2013-05-03 | 2022-08-30 | Tearscience, Inc. | Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis |
| US9795290B2 (en) | 2013-11-15 | 2017-10-24 | Tearscience, Inc. | Ocular tear film peak detection and stabilization detection systems and methods for determining tear film layer characteristics |
| KR102116232B1 (ko) * | 2019-11-12 | 2020-05-28 | (주)로고스바이오시스템스 | 시료 검출 장치 및 이를 이용한 시료 검출 방법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3864571A (en) * | 1971-02-10 | 1975-02-04 | Wheeler International Inc | Method and Apparatus for Automatically, Identifying and Counting Various Cells in Body Fluids |
| US3857033A (en) * | 1972-04-26 | 1974-12-24 | American Science & Eng Inc | Detecting malignant cells |
| US3854050A (en) * | 1973-09-11 | 1974-12-10 | Department Of Health Education | High precision fluorometer for measuring enzymatic substrates in tissue |
-
1973
- 1973-09-14 IL IL43224A patent/IL43224A/xx unknown
-
1974
- 1974-09-11 GB GB39598/74A patent/GB1481605A/en not_active Expired
- 1974-09-12 US US05/505,530 patent/US3971952A/en not_active Expired - Lifetime
- 1974-09-13 JP JP49106584A patent/JPS5075869A/ja active Pending
- 1974-09-13 DE DE19742443950 patent/DE2443950B2/de active Granted
- 1974-09-13 CA CA209,181A patent/CA1008266A/en not_active Expired
- 1974-09-13 FR FR7431129A patent/FR2244175A1/fr not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2953524A1 (de) * | 1978-04-20 | 1981-08-06 | Howard Maurice West Newton Mass. Shapiro | Biologisches messverfahren |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2443950A1 (de) | 1975-03-27 |
| IL43224A0 (en) | 1973-11-28 |
| US3971952A (en) | 1976-07-27 |
| GB1481605A (en) | 1977-08-03 |
| IL43224A (en) | 1979-07-25 |
| JPS5075869A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-06-21 |
| CA1008266A (en) | 1977-04-12 |
| FR2244175A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-04-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C3 | Grant after two publication steps (3rd publication) | ||
| E77 | Valid patent as to the heymanns-index 1977 | ||
| EHJ | Ceased/non-payment of the annual fee |