DE2264193A1 - Verfahren zur herstellung von lysin enthaltenden peptiden - Google Patents

Verfahren zur herstellung von lysin enthaltenden peptiden

Info

Publication number
DE2264193A1
DE2264193A1 DE2264193A DE2264193A DE2264193A1 DE 2264193 A1 DE2264193 A1 DE 2264193A1 DE 2264193 A DE2264193 A DE 2264193A DE 2264193 A DE2264193 A DE 2264193A DE 2264193 A1 DE2264193 A1 DE 2264193A1
Authority
DE
Germany
Prior art keywords
lysine
pyridyl
group
methyloxycarbonyl
amino acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE2264193A
Other languages
German (de)
English (en)
Inventor
Ralph Franz Hirschmann
Daniel Frank Veber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE2264193A1 publication Critical patent/DE2264193A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/064—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for omega-amino or -guanidino functions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE2264193A 1971-12-30 1972-12-29 Verfahren zur herstellung von lysin enthaltenden peptiden Ceased DE2264193A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21438471A 1971-12-30 1971-12-30

Publications (1)

Publication Number Publication Date
DE2264193A1 true DE2264193A1 (de) 1973-07-05

Family

ID=22798896

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2264193A Ceased DE2264193A1 (de) 1971-12-30 1972-12-29 Verfahren zur herstellung von lysin enthaltenden peptiden

Country Status (7)

Country Link
US (1) US3780015A (enExample)
JP (1) JPS5058015A (enExample)
CH (1) CH590824A5 (enExample)
DE (1) DE2264193A1 (enExample)
FR (1) FR2167175A5 (enExample)
GB (1) GB1379937A (enExample)
NL (1) NL7216799A (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4126628A (en) * 1977-03-28 1978-11-21 Canadian Patents And Development Limited Acylation of amino acids
US5556939A (en) * 1994-10-13 1996-09-17 Merck Frosst Canada, Inc. TC or RE radionuclide labelled chelate, hexapeptide complexes useful for diagnostic or therapeutic applications
WO2022020711A1 (en) * 2020-07-24 2022-01-27 The Texas A&M University System Sars-cov-2 main protease inhibitors

Also Published As

Publication number Publication date
US3780015A (en) 1973-12-18
FR2167175A5 (enExample) 1973-08-17
CH590824A5 (enExample) 1977-08-31
GB1379937A (en) 1975-01-08
NL7216799A (enExample) 1973-07-03
JPS5058015A (enExample) 1975-05-20

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Legal Events

Date Code Title Description
OD Request for examination
8131 Rejection