DE20203103U1 - Serotonin-Wiederaufnahme-Inhibitoren - Google Patents

Serotonin-Wiederaufnahme-Inhibitoren

Info

Publication number
DE20203103U1
DE20203103U1 DE20203103U DE20203103U DE20203103U1 DE 20203103 U1 DE20203103 U1 DE 20203103U1 DE 20203103 U DE20203103 U DE 20203103U DE 20203103 U DE20203103 U DE 20203103U DE 20203103 U1 DE20203103 U1 DE 20203103U1
Authority
DE
Germany
Prior art keywords
group
compound
carbomethoxy
octane
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE20203103U
Other languages
German (de)
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harvard College
Organix Inc
Original Assignee
Harvard College
Organix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College, Organix Inc filed Critical Harvard College
Publication of DE20203103U1 publication Critical patent/DE20203103U1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/753Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of polycyclic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/757Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/36Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/44Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing eight carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE20203103U 2001-10-11 2002-02-27 Serotonin-Wiederaufnahme-Inhibitoren Expired - Lifetime DE20203103U1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32853201P 2001-10-11 2001-10-11

Publications (1)

Publication Number Publication Date
DE20203103U1 true DE20203103U1 (de) 2002-07-11

Family

ID=23281370

Family Applications (1)

Application Number Title Priority Date Filing Date
DE20203103U Expired - Lifetime DE20203103U1 (de) 2001-10-11 2002-02-27 Serotonin-Wiederaufnahme-Inhibitoren

Country Status (5)

Country Link
JP (1) JP4071012B2 (ko)
KR (2) KR20030030817A (ko)
CA (2) CA2373559C (ko)
DE (1) DE20203103U1 (ko)
GB (1) GB2380733A (ko)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1429811A1 (en) * 2001-08-17 2004-06-23 President And Fellows Of Harvard College Theurapeutic tropane compounds
EP1478356A2 (en) * 2002-02-08 2004-11-24 President And Fellows Of Harvard College Therapeutic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5496953A (en) * 1990-08-09 1996-03-05 Research Triangle Institute Cocaine receptor binding ligands
US5770180A (en) * 1992-08-24 1998-06-23 Organix, Inc. Bridge-substituted tropanes for methods of imaging and therapy
US5948933A (en) * 1997-07-11 1999-09-07 Organix, Inc. Tropane analogs and methods for inhibition of monoamine transport
KR100446571B1 (ko) * 1996-02-22 2004-11-03 뉴로서치 에이/에스 트로판-유도체,이의제조방법및이를포함하는약제학적조성물

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1429811A1 (en) * 2001-08-17 2004-06-23 President And Fellows Of Harvard College Theurapeutic tropane compounds
EP1429811A4 (en) * 2001-08-17 2006-05-17 Harvard College THEURAPEUTIC TROPICAL COMPOUNDS
EP1478356A2 (en) * 2002-02-08 2004-11-24 President And Fellows Of Harvard College Therapeutic compounds
EP1478356A4 (en) * 2002-02-08 2005-03-16 Harvard College THERAPEUTIC COMPOUNDS
US7439264B2 (en) 2002-02-08 2008-10-21 President And Fellows Of Harvard College Therapeutic compounds

Also Published As

Publication number Publication date
GB2380733A (en) 2003-04-16
CA2373559A1 (en) 2003-04-11
KR20090010133A (ko) 2009-01-28
KR20030030817A (ko) 2003-04-18
JP2003176254A (ja) 2003-06-24
JP4071012B2 (ja) 2008-04-02
CA2373559C (en) 2010-07-27
GB0204596D0 (en) 2002-04-10
CA2506646A1 (en) 2003-04-11

Similar Documents

Publication Publication Date Title
DE69226624T3 (de) Zusammensetzung, die eine tramadol-verbindung und acetaminophen enthält, und ihre verwendung
US3879555A (en) Method of treating drug addicts
CA2143864A1 (en) Morphinan derivatives and pharmaceutical use thereof
Costello et al. A novel series of potent and selective agonists at the opioid κ-receptor
HK18696A (en) Peptides having tachykinin antagonist activity a process for preparation thereof and pharmaceutical compositions comprising the same
CA2233285A1 (en) Pyrazolopyrimidines as crf receptor antagonists
CA2358998A1 (en) Substituted bicyclic derivatives useful as anticancer agents
HK1003708A1 (en) Peripheral vasodilating agent containing n-acylated 4-amino piperidine derivatives as active ingredients
CA2341690A1 (en) Alkynyl-substituted quinolin-2-one derivatives useful as anticancer agents
CA2098076A1 (en) Imidate prodrugs of pharmaceutically useful anticonvulsant sulfamates
CA2073981A1 (en) 2-arylthiazole derivatives and pharmaceutical composition thereof
CA2333703A1 (en) Isothiazole derivatives useful as anticancer agents
WO2001055119A3 (en) Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
EP0915094A4 (en) MORPHINANE DERIVATIVES AND MEDICAL USE THEREOF
Fredericks et al. Comparative in vitro effects of imipramine, oxybutynin, and flavoxate on rabbit detrusor
IE780515L (en) Morphine derivatives
CA2463264A1 (en) 3-azabicyclo (3.1.0) hexane derivatives as opioid receptor antagonists
PL313480A1 (en) Crystalline anhydrous mophethyl mycophenolate and pharmaceutical agent for intravenous administration
CA2036716A1 (en) Disinfectant concentrate and its use as a mycobactericide viricide
DK0458207T3 (ko)
EP1219624A4 (en) REMEDIES AGAINST NEUROPATHIC PAIN AND ANIMAL MODELS OF NEUROPATHIC PAIN
CA2109435A1 (en) Compositions of N-(Phosphonoacetyl)-L-Aspartic Acid and Methods of Their Use as Broad Spectrum Antivirals
DE20203103U1 (de) Serotonin-Wiederaufnahme-Inhibitoren
GR3025207T3 (en) 2-Formylpyridine thiosemicarbazone derivatives, their preparation and their use as antitumor agents
EP0801065A4 (en) 1,4-DIHYDROPYRIDINE COMPOUNDS AND MEDICAL COMPOSITIONS CONTAINING THEM

Legal Events

Date Code Title Description
R207 Utility model specification

Effective date: 20020814

R150 Utility model maintained after payment of first maintenance fee after three years

Effective date: 20050415

R151 Utility model maintained after payment of second maintenance fee after six years

Effective date: 20080424

R152 Utility model maintained after payment of third maintenance fee after eight years

Effective date: 20100319

R071 Expiry of right
R071 Expiry of right