DE19854147A1 - Verwendung von N-substituierten Azabicycloalkan-Derivaten zur Verwendung bei der Bekämpfung der Cocainsucht - Google Patents

Verwendung von N-substituierten Azabicycloalkan-Derivaten zur Verwendung bei der Bekämpfung der Cocainsucht

Info

Publication number
DE19854147A1
DE19854147A1 DE19854147A DE19854147A DE19854147A1 DE 19854147 A1 DE19854147 A1 DE 19854147A1 DE 19854147 A DE19854147 A DE 19854147A DE 19854147 A DE19854147 A DE 19854147A DE 19854147 A1 DE19854147 A1 DE 19854147A1
Authority
DE
Germany
Prior art keywords
azabicyclo
exo
ethyl
fluorophenyl
heptan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19854147A
Other languages
German (de)
English (en)
Inventor
Gerd Steiner
Rainer Munschauer
Gerhard Gross
Martin Traut
Liliane Unger
Hans-Juergen Teschendorf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Priority to DE19854147A priority Critical patent/DE19854147A1/de
Priority to HU0104416A priority patent/HUP0104416A3/hu
Priority to CA002352526A priority patent/CA2352526A1/fr
Priority to CZ20011796A priority patent/CZ20011796A3/cs
Priority to PL99348758A priority patent/PL348758A1/xx
Priority to PCT/EP1999/008734 priority patent/WO2000030639A1/fr
Priority to AU17753/00A priority patent/AU1775300A/en
Priority to TR2001/01476T priority patent/TR200101476T2/xx
Priority to KR1020017006445A priority patent/KR20010080535A/ko
Priority to JP2000583522A priority patent/JP2002530333A/ja
Priority to BR9915589-3A priority patent/BR9915589A/pt
Priority to IL14318199A priority patent/IL143181A0/xx
Priority to SK711-2001A priority patent/SK7112001A3/sk
Priority to EP99960974A priority patent/EP1133293A1/fr
Priority to CN99813559A priority patent/CN1328455A/zh
Priority to ARP990105979A priority patent/AR021502A1/es
Publication of DE19854147A1 publication Critical patent/DE19854147A1/de
Priority to ZA200103976A priority patent/ZA200103976B/en
Priority to NO20012538A priority patent/NO20012538L/no
Priority to BG105549A priority patent/BG105549A/xx
Priority to HR20010472A priority patent/HRP20010472A2/hr
Priority to HK02102768.4A priority patent/HK1040933A1/zh
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
DE19854147A 1998-11-24 1998-11-24 Verwendung von N-substituierten Azabicycloalkan-Derivaten zur Verwendung bei der Bekämpfung der Cocainsucht Withdrawn DE19854147A1 (de)

Priority Applications (21)

Application Number Priority Date Filing Date Title
DE19854147A DE19854147A1 (de) 1998-11-24 1998-11-24 Verwendung von N-substituierten Azabicycloalkan-Derivaten zur Verwendung bei der Bekämpfung der Cocainsucht
IL14318199A IL143181A0 (en) 1998-11-24 1999-11-12 Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system
SK711-2001A SK7112001A3 (en) 1998-11-24 1999-11-12 Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system
CA002352526A CA2352526A1 (fr) 1998-11-24 1999-11-12 Utilisation de derives d'azabicycloalcane substitues par un azote destines au traitement de maladies du systeme nerveux central
PL99348758A PL348758A1 (en) 1998-11-24 1999-11-12 Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system
PCT/EP1999/008734 WO2000030639A1 (fr) 1998-11-24 1999-11-12 Utilisation de derives d'azabicycloalcane substitues par un azote destines au traitement de maladies du systeme nerveux central
AU17753/00A AU1775300A (en) 1998-11-24 1999-11-12 Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system
TR2001/01476T TR200101476T2 (tr) 1998-11-24 1999-11-12 N-ikameli azabisikloaklan türevlerinin merkezi sinir sistemi bozukluklarının tedavisinde kullanılması
KR1020017006445A KR20010080535A (ko) 1998-11-24 1999-11-12 중추신경계 질환의 치료를 위한 ｎ-치환 아자비시클로알칸유도체의 용도
EP99960974A EP1133293A1 (fr) 1998-11-24 1999-11-12 Utilisation de derives d'azabicycloalcane substitues par un azote destines au traitement de maladies du systeme nerveux central
BR9915589-3A BR9915589A (pt) 1998-11-24 1999-11-12 Uso de derivados de azabicicloalcano n-substituìdo
HU0104416A HUP0104416A3 (en) 1998-11-24 1999-11-12 Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system and medicaments containing the compounds
CZ20011796A CZ20011796A3 (cs) 1998-11-24 1999-11-12 Pouľití N-substituovaných azabicycloalkanových derivátů pro léčení poruch centrálního nervového systému
JP2000583522A JP2002530333A (ja) 1998-11-24 1999-11-12 中枢神経系障害の治療用薬剤を製造するためのｎ−置換３−アザビシクロアルカン誘導体使用
CN99813559A CN1328455A (zh) 1998-11-24 1999-11-12 N－取代的氮杂二环烷衍生物在治疗中枢神经系统疾病中的应用
ARP990105979A AR021502A1 (es) 1998-11-24 1999-11-24 Uso de derivados de azabicicloalcanos n-sustituidos para el tratamiento de enfermedades del sistema central nervioso
ZA200103976A ZA200103976B (en) 1998-11-24 2001-05-16 Use of N-substituted azabicycloalkane derivatives for treating diseases of the central nervous system.
NO20012538A NO20012538L (no) 1998-11-24 2001-05-23 Anvendelse av N-substituerte azabicycloalkanderivater for behandling av forstyrrelser i sentralnervesystemet
BG105549A BG105549A (en) 1998-11-24 2001-05-30 Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system
HR20010472A HRP20010472A2 (en) 1998-11-24 2001-06-21 Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system
HK02102768.4A HK1040933A1 (zh) 1998-11-24 2002-04-12 N-取代的氮雜二環烷衍生物在治療中樞神經系統疾病中的應用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19854147A DE19854147A1 (de) 1998-11-24 1998-11-24 Verwendung von N-substituierten Azabicycloalkan-Derivaten zur Verwendung bei der Bekämpfung der Cocainsucht

Publications (1)

Publication Number Publication Date
DE19854147A1 true DE19854147A1 (de) 2000-05-25

Family

ID=7888824

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19854147A Withdrawn DE19854147A1 (de) 1998-11-24 1998-11-24 Verwendung von N-substituierten Azabicycloalkan-Derivaten zur Verwendung bei der Bekämpfung der Cocainsucht

Country Status (21)

Country Link
EP (1) EP1133293A1 (fr)
JP (1) JP2002530333A (fr)
KR (1) KR20010080535A (fr)
CN (1) CN1328455A (fr)
AR (1) AR021502A1 (fr)
AU (1) AU1775300A (fr)
BG (1) BG105549A (fr)
BR (1) BR9915589A (fr)
CA (1) CA2352526A1 (fr)
CZ (1) CZ20011796A3 (fr)
DE (1) DE19854147A1 (fr)
HK (1) HK1040933A1 (fr)
HR (1) HRP20010472A2 (fr)
HU (1) HUP0104416A3 (fr)
IL (1) IL143181A0 (fr)
NO (1) NO20012538L (fr)
PL (1) PL348758A1 (fr)
SK (1) SK7112001A3 (fr)
TR (1) TR200101476T2 (fr)
WO (1) WO2000030639A1 (fr)
ZA (1) ZA200103976B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7576094B2 (en) 2004-12-13 2009-08-18 Eli Lilly And Company Spiro derivatives as lipoxygenase inhibitors

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0812310D0 (en) 2008-07-03 2008-08-13 Syngenta Ltd Novel herbicides
WO2014111837A1 (fr) * 2013-01-15 2014-07-24 Novartis Ag Utilisation d'agonistes des récepteurs nicotiniques de l'acétylcholine alpha 7

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989004311A1 (fr) * 1987-11-12 1989-05-18 American Home Products Corporation Amines polycycliques a activite psychotrope
DE4427648A1 (de) * 1994-08-04 1996-02-08 Basf Ag N-Stubstituierte 3-Azabicyclo[3,2,0,]heptan-Derivate, ihre Herstellung und Verwendung
DE4341403A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
DE4427647A1 (de) * 1994-08-04 1996-02-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7576094B2 (en) 2004-12-13 2009-08-18 Eli Lilly And Company Spiro derivatives as lipoxygenase inhibitors

Also Published As

Publication number Publication date
WO2000030639A1 (fr) 2000-06-02
AU1775300A (en) 2000-06-13
CZ20011796A3 (cs) 2002-05-15
ZA200103976B (en) 2002-05-16
BR9915589A (pt) 2001-08-07
HK1040933A1 (zh) 2002-06-28
JP2002530333A (ja) 2002-09-17
PL348758A1 (en) 2002-06-03
HUP0104416A2 (hu) 2002-04-29
SK7112001A3 (en) 2001-12-03
BG105549A (en) 2001-12-29
EP1133293A1 (fr) 2001-09-19
IL143181A0 (en) 2002-04-21
HUP0104416A3 (en) 2002-11-28
NO20012538D0 (no) 2001-05-23
KR20010080535A (ko) 2001-08-22
TR200101476T2 (tr) 2001-10-22
AR021502A1 (es) 2002-07-24
HRP20010472A2 (en) 2003-04-30
CA2352526A1 (fr) 2000-06-02
CN1328455A (zh) 2001-12-26
NO20012538L (no) 2001-07-04

Similar Documents

Publication Publication Date Title
US11464781B2 (en) PDE1 inhibitors for ophthalmic disorders
EP2021006B1 (fr) Utilisation de flibanserine pour le traitement des troubles de la libido post-menopausiques
DE60200492T2 (de) Kombination eines Inhibitoren der Serotoninwiederaufnahme und eines atypischen Antipsychotikums zur Behandlung von Depression, Zwangsneurosen und Psychosen
KR20160005341A (ko) Ampk 활성인자 및 세로토닌성 제제를 포함하는 약학 조성물 및 이의 사용 방법
JP3076065B2 (ja) ドパミン系の障害を治療するためのフェノキシピペラジン誘導体
KR20150034209A (ko) 디안하이드로갈락티톨, 디아세틸디안하이드로갈락티톨, 디브로모둘시톨, 또는 그의 유사체 또는 유도체를 이용하여 유전학적 다형성이 있는 환자에 있어서 티로신-키나아제-억제제 내성 악성종양, ahi1 조절곤란 또는 돌연변이를 치료하는 방법
JP2004504376A (ja) 医薬製剤としてのセロトニンアゴニスト（５ｈｔ２）とアンタゴニスト（５ｈｔ６）の新規組み合わせ
WO2022030428A1 (fr) Composition pharmaceutique pour la prévention, la suppression ou le traitement de symptômes associés à une réaction allergique
US20040029972A1 (en) Combination treatment for depression
US20030235631A1 (en) Combination treatment for depression and anxiety
US20040048869A1 (en) Combination treatment for depression, anxiety and psychosis
US20020049211A1 (en) Combination treatment for depression and anxiety
WO2018148737A1 (fr) Agonistes inverses du récepteur 5-ht2a de la sérotonine utiles pour la prophylaxie et le traitement de symptômes parkinsoniens associés à une maladie neurodégénérative
AU600852B2 (en) Treatment of alcoholism using 2-pyrimidinyl-1-piperazine derivative
US4208417A (en) Indole derivatives and their use as anxiolytics
KR20080107429A (ko) 정신병적 장애의 치료 또는 예방용의 신규한 치료학적 배합물
DE19854147A1 (de) Verwendung von N-substituierten Azabicycloalkan-Derivaten zur Verwendung bei der Bekämpfung der Cocainsucht
SK1652004A3 (sk) Použitie inhibítorov fosfodiesterázy IV
ZA200209272B (en) Aromatic polyurethane polyol.
GB2303303A (en) 5HT-1A and 5HT-2 antagonists for treating side-effects of serotonin re-uptake inhibitors
MXPA01005104A (en) Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system
HU205855B (en) Process for producing anxciety-solving pharmaceutical composition
Land et al. Risperidone: a novel antipsychotic medication
Micheletto et al. Antipsychotics 17
CA2489791A1 (fr) Combinaisons d'inhibiteurs de pde-v et d'antagonistes du recepteur nk1 pour le traitement de l'anxiete ou de la depression

Legal Events

Date Code Title Description
8130 Withdrawal